Chemometrical-electrochemical investigation for comparing inhibitory effects of quercetin and its sulfonamide derivative on human carbonic anhydrase II: Theoretical and experimenta...

Autores
Khodarahmi, Reza; Khateri, Shaya; Adibi, Hadi; Nasirian, Vahid; Hedayati, Mehdi; Faramarzi, Elahe; Soleimani, Shokoufeh; Goicoechea, Hector Casimiro; Jalalvand, Ali Reza
Año de publicación
2019
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
This paper reports results of a valuable study on investigation of inhibitory effects of the sulfonamide derivative of quercetin (QD) on human carbonic anhydrase II (CA-II) by electrochemical and chemometrical approaches. To achieve this goal, a glassy carbon electrode (GCE) was chosen as the sensing platform and different electrochemical techniques such as cyclic voltammetry (CV), differential pulse voltammetry (DPV), linear sweep voltammetry (LSV) and electrochemical impedance spectroscopy (EIS) were used to investigate and comparing inhibitory effects of quercetin (Q) and QD on CA-II. By the use of EQUISPEC, SPECFIT, SQUAD and REACTLAB as efficient hard-modeling algorithms, bindings of Q and QD with CA-II were investigated and the results confirmed that the QD inhibited the CA-II stronger than Q suggesting a highly relevant role of QD's-SO2NH2 group in inhibiting activity and also was confirmed by docking studies. Finally, a novel EIS technique based on interaction of Q and CA-II was developed for sensitive electroanalytical determination of CA-II and in this section of our study, the sensitivity of the developed electroanalytical methodology was improved by the modification of the GCE was with multi-walled carbon nanotubes-ionic liquid.
Fil: Khodarahmi, Reza. Kermanshah University of Medical Sciences; Irán
Fil: Khateri, Shaya. Kermanshah University of Medical Sciences; Irán
Fil: Adibi, Hadi. Kermanshah University of Medical Sciences; Irán
Fil: Nasirian, Vahid. State University of Louisiana; Estados Unidos
Fil: Hedayati, Mehdi. Kermanshah University of Medical Sciences; Irán
Fil: Faramarzi, Elahe. Kermanshah University of Medical Sciences; Irán
Fil: Soleimani, Shokoufeh. Kermanshah University of Medical Sciences; Irán
Fil: Goicoechea, Hector Casimiro. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Laboratorio de Desarrollo Analítico y Quimiometría; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste; Argentina
Fil: Jalalvand, Ali Reza. Kermanshah University Of Medical Sciences; Irán
Materia
HUMAN CARBONIC ANHYDRASE II
QUERCETIN
QUERCETIN DERIVATIVE
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/127048
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/127048
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Chemometrical-electrochemical investigation for comparing inhibitory effects of quercetin and its sulfonamide derivative on human carbonic anhydrase II: Theoretical and experimental evidenceKhodarahmi, RezaKhateri, ShayaAdibi, HadiNasirian, VahidHedayati, MehdiFaramarzi, ElaheSoleimani, ShokoufehGoicoechea, Hector CasimiroJalalvand, Ali RezaHUMAN CARBONIC ANHYDRASE IIQUERCETINQUERCETIN DERIVATIVEhttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1This paper reports results of a valuable study on investigation of inhibitory effects of the sulfonamide derivative of quercetin (QD) on human carbonic anhydrase II (CA-II) by electrochemical and chemometrical approaches. To achieve this goal, a glassy carbon electrode (GCE) was chosen as the sensing platform and different electrochemical techniques such as cyclic voltammetry (CV), differential pulse voltammetry (DPV), linear sweep voltammetry (LSV) and electrochemical impedance spectroscopy (EIS) were used to investigate and comparing inhibitory effects of quercetin (Q) and QD on CA-II. By the use of EQUISPEC, SPECFIT, SQUAD and REACTLAB as efficient hard-modeling algorithms, bindings of Q and QD with CA-II were investigated and the results confirmed that the QD inhibited the CA-II stronger than Q suggesting a highly relevant role of QD's-SO2NH2 group in inhibiting activity and also was confirmed by docking studies. Finally, a novel EIS technique based on interaction of Q and CA-II was developed for sensitive electroanalytical determination of CA-II and in this section of our study, the sensitivity of the developed electroanalytical methodology was improved by the modification of the GCE was with multi-walled carbon nanotubes-ionic liquid.Fil: Khodarahmi, Reza. Kermanshah University of Medical Sciences; IránFil: Khateri, Shaya. Kermanshah University of Medical Sciences; IránFil: Adibi, Hadi. Kermanshah University of Medical Sciences; IránFil: Nasirian, Vahid. State University of Louisiana; Estados UnidosFil: Hedayati, Mehdi. Kermanshah University of Medical Sciences; IránFil: Faramarzi, Elahe. Kermanshah University of Medical Sciences; IránFil: Soleimani, Shokoufeh. Kermanshah University of Medical Sciences; IránFil: Goicoechea, Hector Casimiro. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Laboratorio de Desarrollo Analítico y Quimiometría; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste; ArgentinaFil: Jalalvand, Ali Reza. Kermanshah University Of Medical Sciences; IránElsevier Science2019-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/127048Khodarahmi, Reza; Khateri, Shaya; Adibi, Hadi; Nasirian, Vahid; Hedayati, Mehdi; et al.; Chemometrical-electrochemical investigation for comparing inhibitory effects of quercetin and its sulfonamide derivative on human carbonic anhydrase II: Theoretical and experimental evidence; Elsevier Science; International Journal of Biological Macromolecules; 136; 1-9-2019; 377-3850141-8130CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://linkinghub.elsevier.com/retrieve/pii/S0141813019335317info:eu-repo/semantics/altIdentifier/doi/10.1016/j.ijbiomac.2019.06.093info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:01:50Zoai:ri.conicet.gov.ar:11336/127048instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:01:50.923CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Chemometrical-electrochemical investigation for comparing inhibitory effects of quercetin and its sulfonamide derivative on human carbonic anhydrase II: Theoretical and experimental evidence
title Chemometrical-electrochemical investigation for comparing inhibitory effects of quercetin and its sulfonamide derivative on human carbonic anhydrase II: Theoretical and experimental evidence
spellingShingle Chemometrical-electrochemical investigation for comparing inhibitory effects of quercetin and its sulfonamide derivative on human carbonic anhydrase II: Theoretical and experimental evidence
Khodarahmi, Reza
HUMAN CARBONIC ANHYDRASE II
QUERCETIN
QUERCETIN DERIVATIVE
title_short Chemometrical-electrochemical investigation for comparing inhibitory effects of quercetin and its sulfonamide derivative on human carbonic anhydrase II: Theoretical and experimental evidence
title_full Chemometrical-electrochemical investigation for comparing inhibitory effects of quercetin and its sulfonamide derivative on human carbonic anhydrase II: Theoretical and experimental evidence
title_fullStr Chemometrical-electrochemical investigation for comparing inhibitory effects of quercetin and its sulfonamide derivative on human carbonic anhydrase II: Theoretical and experimental evidence
title_full_unstemmed Chemometrical-electrochemical investigation for comparing inhibitory effects of quercetin and its sulfonamide derivative on human carbonic anhydrase II: Theoretical and experimental evidence
title_sort Chemometrical-electrochemical investigation for comparing inhibitory effects of quercetin and its sulfonamide derivative on human carbonic anhydrase II: Theoretical and experimental evidence
dc.creator.none.fl_str_mv Khodarahmi, Reza
Khateri, Shaya
Adibi, Hadi
Nasirian, Vahid
Hedayati, Mehdi
Faramarzi, Elahe
Soleimani, Shokoufeh
Goicoechea, Hector Casimiro
Jalalvand, Ali Reza
author Khodarahmi, Reza
author_facet Khodarahmi, Reza
Khateri, Shaya
Adibi, Hadi
Nasirian, Vahid
Hedayati, Mehdi
Faramarzi, Elahe
Soleimani, Shokoufeh
Goicoechea, Hector Casimiro
Jalalvand, Ali Reza
author_role author
author2 Khateri, Shaya
Adibi, Hadi
Nasirian, Vahid
Hedayati, Mehdi
Faramarzi, Elahe
Soleimani, Shokoufeh
Goicoechea, Hector Casimiro
Jalalvand, Ali Reza
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv HUMAN CARBONIC ANHYDRASE II
QUERCETIN
QUERCETIN DERIVATIVE
topic HUMAN CARBONIC ANHYDRASE II
QUERCETIN
QUERCETIN DERIVATIVE
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv This paper reports results of a valuable study on investigation of inhibitory effects of the sulfonamide derivative of quercetin (QD) on human carbonic anhydrase II (CA-II) by electrochemical and chemometrical approaches. To achieve this goal, a glassy carbon electrode (GCE) was chosen as the sensing platform and different electrochemical techniques such as cyclic voltammetry (CV), differential pulse voltammetry (DPV), linear sweep voltammetry (LSV) and electrochemical impedance spectroscopy (EIS) were used to investigate and comparing inhibitory effects of quercetin (Q) and QD on CA-II. By the use of EQUISPEC, SPECFIT, SQUAD and REACTLAB as efficient hard-modeling algorithms, bindings of Q and QD with CA-II were investigated and the results confirmed that the QD inhibited the CA-II stronger than Q suggesting a highly relevant role of QD's-SO2NH2 group in inhibiting activity and also was confirmed by docking studies. Finally, a novel EIS technique based on interaction of Q and CA-II was developed for sensitive electroanalytical determination of CA-II and in this section of our study, the sensitivity of the developed electroanalytical methodology was improved by the modification of the GCE was with multi-walled carbon nanotubes-ionic liquid.
Fil: Khodarahmi, Reza. Kermanshah University of Medical Sciences; Irán
Fil: Khateri, Shaya. Kermanshah University of Medical Sciences; Irán
Fil: Adibi, Hadi. Kermanshah University of Medical Sciences; Irán
Fil: Nasirian, Vahid. State University of Louisiana; Estados Unidos
Fil: Hedayati, Mehdi. Kermanshah University of Medical Sciences; Irán
Fil: Faramarzi, Elahe. Kermanshah University of Medical Sciences; Irán
Fil: Soleimani, Shokoufeh. Kermanshah University of Medical Sciences; Irán
Fil: Goicoechea, Hector Casimiro. Universidad Nacional del Litoral. Facultad de Bioquímica y Ciencias Biológicas. Laboratorio de Desarrollo Analítico y Quimiometría; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste; Argentina
Fil: Jalalvand, Ali Reza. Kermanshah University Of Medical Sciences; Irán
description This paper reports results of a valuable study on investigation of inhibitory effects of the sulfonamide derivative of quercetin (QD) on human carbonic anhydrase II (CA-II) by electrochemical and chemometrical approaches. To achieve this goal, a glassy carbon electrode (GCE) was chosen as the sensing platform and different electrochemical techniques such as cyclic voltammetry (CV), differential pulse voltammetry (DPV), linear sweep voltammetry (LSV) and electrochemical impedance spectroscopy (EIS) were used to investigate and comparing inhibitory effects of quercetin (Q) and QD on CA-II. By the use of EQUISPEC, SPECFIT, SQUAD and REACTLAB as efficient hard-modeling algorithms, bindings of Q and QD with CA-II were investigated and the results confirmed that the QD inhibited the CA-II stronger than Q suggesting a highly relevant role of QD's-SO2NH2 group in inhibiting activity and also was confirmed by docking studies. Finally, a novel EIS technique based on interaction of Q and CA-II was developed for sensitive electroanalytical determination of CA-II and in this section of our study, the sensitivity of the developed electroanalytical methodology was improved by the modification of the GCE was with multi-walled carbon nanotubes-ionic liquid.
publishDate 2019
dc.date.none.fl_str_mv 2019-09-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/127048
Khodarahmi, Reza; Khateri, Shaya; Adibi, Hadi; Nasirian, Vahid; Hedayati, Mehdi; et al.; Chemometrical-electrochemical investigation for comparing inhibitory effects of quercetin and its sulfonamide derivative on human carbonic anhydrase II: Theoretical and experimental evidence; Elsevier Science; International Journal of Biological Macromolecules; 136; 1-9-2019; 377-385
0141-8130
CONICET Digital
CONICET
url http://hdl.handle.net/11336/127048
identifier_str_mv Khodarahmi, Reza; Khateri, Shaya; Adibi, Hadi; Nasirian, Vahid; Hedayati, Mehdi; et al.; Chemometrical-electrochemical investigation for comparing inhibitory effects of quercetin and its sulfonamide derivative on human carbonic anhydrase II: Theoretical and experimental evidence; Elsevier Science; International Journal of Biological Macromolecules; 136; 1-9-2019; 377-385
0141-8130
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://linkinghub.elsevier.com/retrieve/pii/S0141813019335317
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.ijbiomac.2019.06.093
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Science
publisher.none.fl_str_mv Elsevier Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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