Beating the odds: Sustained Chagas disease vector control in remote indigenous communities of the Argentine Chaco over a seven-year period

Autores
Gaspe, Maria Sol; Provecho, Yael Mariana; Fernández, María P.; Vassena, Claudia Viviana; Santo Orihuela, Pablo Luis; Gurtler, Ricardo Esteban
Año de publicación
2018
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
BACKGROUND: Rapid reinfestation of insecticide-treated dwellings hamper the sustained elimination of Triatoma infestans, the main vector of Chagas disease in the Gran Chaco region. We conducted a seven-year longitudinal study including community-wide spraying with pyrethroid insecticides combined with periodic vector surveillance to investigate the house reinfestation process in connection with baseline pyrethroid resistance, housing quality and household mobility in a rural section of Pampa del Indio mainly inhabited by deprived indigenous people (Qom). METHODOLOGY/PRINCIPAL FINDINGS: Despite evidence of moderate pyrethroid resistance in local T. infestans populations, house infestation dropped from 31.9% at baseline to 0.7% at 10 months post-spraying (MPS), with no triatomine found at 59 and 78 MPS. Household-based surveillance corroborated the rare occurrence of T. infestans and the house invasion of other four triatomine species. The annual rates of loss of initially occupied houses and of household mobility were high (4.6-8.0%). Housing improvements did not translate into a significant reduction of mud-walled houses and refuges for triatomines because most households kept the former dwelling or built new ones with mud walls. CONCLUSIONS/SIGNIFICANCE: Our results refute the assumption that vector control actions performed in marginalized communities of the Gran Chaco are doomed to fail. The larger-than-expected impacts of the intervention program were likely associated with the combined effects of high-coverage, professional insecticide spraying followed by systematic vector surveillance-and-response, broad geographic coverage creating a buffer zone, frequent housing replacement and residential mobility. The dynamical interactions among housing quality, mobility and insecticide-based control largely affect the chances of vector elimination.
Fil: M. Sol Gaspe. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales, Laboratorio de EcoEpidemiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas-Universidad de Buenos Aires. Instituto de Ecología, Genética y Evolución de Buenos Aires (IEGEBA); Argentina
Fil: Yael M. Provecho. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales, Laboratorio de EcoEpidemiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas-Universidad de Buenos Aires. Instituto de Ecología, Genética y Evolución de Buenos Aires (IEGEBA); Argentina. Coordinación de Vectores, Dirección Nacional de Epidemiología y Análisis de la Situación de Salud, Ministerio de Salud de la Nación; Argentina
Fil: María P. Fernández. Universidad de Buenos Aires; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas-Universidad de Buenos Aires. Instituto de Ecología, Genética y Evolución de Buenos Aires (IEGEBA); Argentina. Earth Institute, Columbia University; Estados Unidos
Fil: Claudia V. Vassena. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Centro de Investigaciones de Plagas e Insecticidas (UNIDEF, CITEDEF, CONICET, CIPEIN); Argentina. Cátedra de Química Analítica Instrumental, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires; Argentina
Fil: Pablo L. Santo Orihuela. Centro de Investigaciones de Plagas e Insecticidas (UNIDEF, CITEDEF, CONICET, CIPEIN); Argentina. Departamento de Investigación e Ingeniería Ambiental (3iA), Universidad Nacional de San Martín; Argentina
Fil: Ricardo E. Gu¨rtler. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales, Laboratorio de EcoEpidemiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas-Universidad de Buenos Aires. Instituto de Ecología, Genética y Evolución de Buenos Aires (IEGEBA); Argentina
Materia
TRIATOMA INFESTANS
ENTOMOLOGICAL SURVEILLANCE
POPULATION MOBILITY
GRAN CHACO
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/94884
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Beating the odds: Sustained Chagas disease vector control in remote indigenous communities of the Argentine Chaco over a seven-year periodGaspe, Maria SolProvecho, Yael MarianaFernández, María P.Vassena, Claudia VivianaSanto Orihuela, Pablo LuisGurtler, Ricardo EstebanTRIATOMA INFESTANSENTOMOLOGICAL SURVEILLANCEPOPULATION MOBILITYGRAN CHACOhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1BACKGROUND: Rapid reinfestation of insecticide-treated dwellings hamper the sustained elimination of Triatoma infestans, the main vector of Chagas disease in the Gran Chaco region. We conducted a seven-year longitudinal study including community-wide spraying with pyrethroid insecticides combined with periodic vector surveillance to investigate the house reinfestation process in connection with baseline pyrethroid resistance, housing quality and household mobility in a rural section of Pampa del Indio mainly inhabited by deprived indigenous people (Qom). METHODOLOGY/PRINCIPAL FINDINGS: Despite evidence of moderate pyrethroid resistance in local T. infestans populations, house infestation dropped from 31.9% at baseline to 0.7% at 10 months post-spraying (MPS), with no triatomine found at 59 and 78 MPS. Household-based surveillance corroborated the rare occurrence of T. infestans and the house invasion of other four triatomine species. The annual rates of loss of initially occupied houses and of household mobility were high (4.6-8.0%). Housing improvements did not translate into a significant reduction of mud-walled houses and refuges for triatomines because most households kept the former dwelling or built new ones with mud walls. CONCLUSIONS/SIGNIFICANCE: Our results refute the assumption that vector control actions performed in marginalized communities of the Gran Chaco are doomed to fail. The larger-than-expected impacts of the intervention program were likely associated with the combined effects of high-coverage, professional insecticide spraying followed by systematic vector surveillance-and-response, broad geographic coverage creating a buffer zone, frequent housing replacement and residential mobility. The dynamical interactions among housing quality, mobility and insecticide-based control largely affect the chances of vector elimination.Fil: M. Sol Gaspe. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales, Laboratorio de EcoEpidemiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas-Universidad de Buenos Aires. Instituto de Ecología, Genética y Evolución de Buenos Aires (IEGEBA); ArgentinaFil: Yael M. Provecho. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales, Laboratorio de EcoEpidemiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas-Universidad de Buenos Aires. Instituto de Ecología, Genética y Evolución de Buenos Aires (IEGEBA); Argentina. Coordinación de Vectores, Dirección Nacional de Epidemiología y Análisis de la Situación de Salud, Ministerio de Salud de la Nación; ArgentinaFil: María P. Fernández. Universidad de Buenos Aires; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas-Universidad de Buenos Aires. Instituto de Ecología, Genética y Evolución de Buenos Aires (IEGEBA); Argentina. Earth Institute, Columbia University; Estados UnidosFil: Claudia V. Vassena. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Centro de Investigaciones de Plagas e Insecticidas (UNIDEF, CITEDEF, CONICET, CIPEIN); Argentina. Cátedra de Química Analítica Instrumental, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires; ArgentinaFil: Pablo L. Santo Orihuela. Centro de Investigaciones de Plagas e Insecticidas (UNIDEF, CITEDEF, CONICET, CIPEIN); Argentina. Departamento de Investigación e Ingeniería Ambiental (3iA), Universidad Nacional de San Martín; ArgentinaFil: Ricardo E. Gu¨rtler. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales, Laboratorio de EcoEpidemiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas-Universidad de Buenos Aires. Instituto de Ecología, Genética y Evolución de Buenos Aires (IEGEBA); ArgentinaPublic Library of Science2018-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/94884Gaspe, Maria Sol; Provecho, Yael Mariana; Fernández, María P.; Vassena, Claudia Viviana; Santo Orihuela, Pablo Luis; et al.; Beating the odds: Sustained Chagas disease vector control in remote indigenous communities of the Argentine Chaco over a seven-year period; Public Library of Science; Neglected Tropical Diseases; 12; 10; 10-2018; 1-261935-2735CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0006804info:eu-repo/semantics/altIdentifier/doi/10.1371/journal.pntd.0006804info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:42:44Zoai:ri.conicet.gov.ar:11336/94884instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:42:44.751CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Beating the odds: Sustained Chagas disease vector control in remote indigenous communities of the Argentine Chaco over a seven-year period
title Beating the odds: Sustained Chagas disease vector control in remote indigenous communities of the Argentine Chaco over a seven-year period
spellingShingle Beating the odds: Sustained Chagas disease vector control in remote indigenous communities of the Argentine Chaco over a seven-year period
Gaspe, Maria Sol
TRIATOMA INFESTANS
ENTOMOLOGICAL SURVEILLANCE
POPULATION MOBILITY
GRAN CHACO
title_short Beating the odds: Sustained Chagas disease vector control in remote indigenous communities of the Argentine Chaco over a seven-year period
title_full Beating the odds: Sustained Chagas disease vector control in remote indigenous communities of the Argentine Chaco over a seven-year period
title_fullStr Beating the odds: Sustained Chagas disease vector control in remote indigenous communities of the Argentine Chaco over a seven-year period
title_full_unstemmed Beating the odds: Sustained Chagas disease vector control in remote indigenous communities of the Argentine Chaco over a seven-year period
title_sort Beating the odds: Sustained Chagas disease vector control in remote indigenous communities of the Argentine Chaco over a seven-year period
dc.creator.none.fl_str_mv Gaspe, Maria Sol
Provecho, Yael Mariana
Fernández, María P.
Vassena, Claudia Viviana
Santo Orihuela, Pablo Luis
Gurtler, Ricardo Esteban
author Gaspe, Maria Sol
author_facet Gaspe, Maria Sol
Provecho, Yael Mariana
Fernández, María P.
Vassena, Claudia Viviana
Santo Orihuela, Pablo Luis
Gurtler, Ricardo Esteban
author_role author
author2 Provecho, Yael Mariana
Fernández, María P.
Vassena, Claudia Viviana
Santo Orihuela, Pablo Luis
Gurtler, Ricardo Esteban
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv TRIATOMA INFESTANS
ENTOMOLOGICAL SURVEILLANCE
POPULATION MOBILITY
GRAN CHACO
topic TRIATOMA INFESTANS
ENTOMOLOGICAL SURVEILLANCE
POPULATION MOBILITY
GRAN CHACO
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv BACKGROUND: Rapid reinfestation of insecticide-treated dwellings hamper the sustained elimination of Triatoma infestans, the main vector of Chagas disease in the Gran Chaco region. We conducted a seven-year longitudinal study including community-wide spraying with pyrethroid insecticides combined with periodic vector surveillance to investigate the house reinfestation process in connection with baseline pyrethroid resistance, housing quality and household mobility in a rural section of Pampa del Indio mainly inhabited by deprived indigenous people (Qom). METHODOLOGY/PRINCIPAL FINDINGS: Despite evidence of moderate pyrethroid resistance in local T. infestans populations, house infestation dropped from 31.9% at baseline to 0.7% at 10 months post-spraying (MPS), with no triatomine found at 59 and 78 MPS. Household-based surveillance corroborated the rare occurrence of T. infestans and the house invasion of other four triatomine species. The annual rates of loss of initially occupied houses and of household mobility were high (4.6-8.0%). Housing improvements did not translate into a significant reduction of mud-walled houses and refuges for triatomines because most households kept the former dwelling or built new ones with mud walls. CONCLUSIONS/SIGNIFICANCE: Our results refute the assumption that vector control actions performed in marginalized communities of the Gran Chaco are doomed to fail. The larger-than-expected impacts of the intervention program were likely associated with the combined effects of high-coverage, professional insecticide spraying followed by systematic vector surveillance-and-response, broad geographic coverage creating a buffer zone, frequent housing replacement and residential mobility. The dynamical interactions among housing quality, mobility and insecticide-based control largely affect the chances of vector elimination.
Fil: M. Sol Gaspe. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales, Laboratorio de EcoEpidemiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas-Universidad de Buenos Aires. Instituto de Ecología, Genética y Evolución de Buenos Aires (IEGEBA); Argentina
Fil: Yael M. Provecho. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales, Laboratorio de EcoEpidemiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas-Universidad de Buenos Aires. Instituto de Ecología, Genética y Evolución de Buenos Aires (IEGEBA); Argentina. Coordinación de Vectores, Dirección Nacional de Epidemiología y Análisis de la Situación de Salud, Ministerio de Salud de la Nación; Argentina
Fil: María P. Fernández. Universidad de Buenos Aires; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas-Universidad de Buenos Aires. Instituto de Ecología, Genética y Evolución de Buenos Aires (IEGEBA); Argentina. Earth Institute, Columbia University; Estados Unidos
Fil: Claudia V. Vassena. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Centro de Investigaciones de Plagas e Insecticidas (UNIDEF, CITEDEF, CONICET, CIPEIN); Argentina. Cátedra de Química Analítica Instrumental, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires; Argentina
Fil: Pablo L. Santo Orihuela. Centro de Investigaciones de Plagas e Insecticidas (UNIDEF, CITEDEF, CONICET, CIPEIN); Argentina. Departamento de Investigación e Ingeniería Ambiental (3iA), Universidad Nacional de San Martín; Argentina
Fil: Ricardo E. Gu¨rtler. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales, Laboratorio de EcoEpidemiología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas-Universidad de Buenos Aires. Instituto de Ecología, Genética y Evolución de Buenos Aires (IEGEBA); Argentina
description BACKGROUND: Rapid reinfestation of insecticide-treated dwellings hamper the sustained elimination of Triatoma infestans, the main vector of Chagas disease in the Gran Chaco region. We conducted a seven-year longitudinal study including community-wide spraying with pyrethroid insecticides combined with periodic vector surveillance to investigate the house reinfestation process in connection with baseline pyrethroid resistance, housing quality and household mobility in a rural section of Pampa del Indio mainly inhabited by deprived indigenous people (Qom). METHODOLOGY/PRINCIPAL FINDINGS: Despite evidence of moderate pyrethroid resistance in local T. infestans populations, house infestation dropped from 31.9% at baseline to 0.7% at 10 months post-spraying (MPS), with no triatomine found at 59 and 78 MPS. Household-based surveillance corroborated the rare occurrence of T. infestans and the house invasion of other four triatomine species. The annual rates of loss of initially occupied houses and of household mobility were high (4.6-8.0%). Housing improvements did not translate into a significant reduction of mud-walled houses and refuges for triatomines because most households kept the former dwelling or built new ones with mud walls. CONCLUSIONS/SIGNIFICANCE: Our results refute the assumption that vector control actions performed in marginalized communities of the Gran Chaco are doomed to fail. The larger-than-expected impacts of the intervention program were likely associated with the combined effects of high-coverage, professional insecticide spraying followed by systematic vector surveillance-and-response, broad geographic coverage creating a buffer zone, frequent housing replacement and residential mobility. The dynamical interactions among housing quality, mobility and insecticide-based control largely affect the chances of vector elimination.
publishDate 2018
dc.date.none.fl_str_mv 2018-10
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/94884
Gaspe, Maria Sol; Provecho, Yael Mariana; Fernández, María P.; Vassena, Claudia Viviana; Santo Orihuela, Pablo Luis; et al.; Beating the odds: Sustained Chagas disease vector control in remote indigenous communities of the Argentine Chaco over a seven-year period; Public Library of Science; Neglected Tropical Diseases; 12; 10; 10-2018; 1-26
1935-2735
CONICET Digital
CONICET
url http://hdl.handle.net/11336/94884
identifier_str_mv Gaspe, Maria Sol; Provecho, Yael Mariana; Fernández, María P.; Vassena, Claudia Viviana; Santo Orihuela, Pablo Luis; et al.; Beating the odds: Sustained Chagas disease vector control in remote indigenous communities of the Argentine Chaco over a seven-year period; Public Library of Science; Neglected Tropical Diseases; 12; 10; 10-2018; 1-26
1935-2735
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
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info:eu-repo/semantics/altIdentifier/doi/10.1371/journal.pntd.0006804
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
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eu_rights_str_mv openAccess
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dc.format.none.fl_str_mv application/pdf
application/pdf
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dc.publisher.none.fl_str_mv Public Library of Science
publisher.none.fl_str_mv Public Library of Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
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reponame_str CONICET Digital (CONICET)
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repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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