Insights into the non-coding RNome of nitrogen-fixing endosymbiotic α-proteobacteria

Autores
Jiménez Zurdo, José I.; Valverde, Claudio Fabián; Becker, Anke
Año de publicación
2013
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Symbiotic chronic infection of legumes by rhizobia involves transition of invading bacteria from a free-living environment in soil to an intracellular state as differentiated nitrogen-fixing bacteroids within the nodules elicited in the host plant. The adaptive flexibility demanded by this complex lifestyle is likely facilitated by the large set of regulatory proteins encoded by rhizobial genomes. However, proteins are not the only relevant players in the regulation of gene expression in bacteria. Large-scale high-throughput analysis of prokaryotic genomes is evidencing the expression of an unexpected plethora of small untranslated transcripts (sRNAs) with housekeeping or regulatory roles. sRNAs mostly act in response to environmental cues as post-transcriptional regulators of gene expression through protein-assisted base-pairing interactions with target mRNAs. Riboregulation contributes to fine-tune a wide range of bacterial processes which, in intracellular animal pathogens, largely compromise virulence traits. Here we summarize the incipient knowledge about the non-coding RNome structure of nitrogen-fixing endosymbiotic bacteria as inferred from genome-wide searches for sRNA genes in the alfalfa partner Sinorhizobium meliloti and further comparative genomics analysis. The biology of relevant S. meliloti RNA chaperones (e.g. Hfq) is also reviewed as a first global indicator of the impact of riboregulation in the establishment of the symbiotic interaction.
Fil: Jiménez Zurdo, José I.. Consejo Superior de Investigaciones Científicas. Estación Experimental del Zaidín; España
Fil: Valverde, Claudio Fabián. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; Argentina
Fil: Becker, Anke. Philipps-Universität Marburg; Alemania
Materia
Riboregulation
sRNAs
Hfq
rhizobia
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/22744
Acceder
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network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Insights into the non-coding RNome of nitrogen-fixing endosymbiotic α-proteobacteriaJiménez Zurdo, José I.Valverde, Claudio FabiánBecker, AnkeRiboregulationsRNAsHfqrhizobiahttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Symbiotic chronic infection of legumes by rhizobia involves transition of invading bacteria from a free-living environment in soil to an intracellular state as differentiated nitrogen-fixing bacteroids within the nodules elicited in the host plant. The adaptive flexibility demanded by this complex lifestyle is likely facilitated by the large set of regulatory proteins encoded by rhizobial genomes. However, proteins are not the only relevant players in the regulation of gene expression in bacteria. Large-scale high-throughput analysis of prokaryotic genomes is evidencing the expression of an unexpected plethora of small untranslated transcripts (sRNAs) with housekeeping or regulatory roles. sRNAs mostly act in response to environmental cues as post-transcriptional regulators of gene expression through protein-assisted base-pairing interactions with target mRNAs. Riboregulation contributes to fine-tune a wide range of bacterial processes which, in intracellular animal pathogens, largely compromise virulence traits. Here we summarize the incipient knowledge about the non-coding RNome structure of nitrogen-fixing endosymbiotic bacteria as inferred from genome-wide searches for sRNA genes in the alfalfa partner Sinorhizobium meliloti and further comparative genomics analysis. The biology of relevant S. meliloti RNA chaperones (e.g. Hfq) is also reviewed as a first global indicator of the impact of riboregulation in the establishment of the symbiotic interaction.Fil: Jiménez Zurdo, José I.. Consejo Superior de Investigaciones Científicas. Estación Experimental del Zaidín; EspañaFil: Valverde, Claudio Fabián. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; ArgentinaFil: Becker, Anke. Philipps-Universität Marburg; AlemaniaAmerican Phytopathological Society2013-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/22744Jiménez Zurdo, José I.; Valverde, Claudio Fabián; Becker, Anke; Insights into the non-coding RNome of nitrogen-fixing endosymbiotic α-proteobacteria; American Phytopathological Society; Molecular Plant-Microbe Interactions; 26; 2; 2-2013; 160-1670894-0282CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://apsjournals.apsnet.org/loi/mpmiinfo:eu-repo/semantics/altIdentifier/doi/10.1094/MPMI-07-12-0186-CRinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T15:29:07Zoai:ri.conicet.gov.ar:11336/22744instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 15:29:07.635CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Insights into the non-coding RNome of nitrogen-fixing endosymbiotic α-proteobacteria
title Insights into the non-coding RNome of nitrogen-fixing endosymbiotic α-proteobacteria
spellingShingle Insights into the non-coding RNome of nitrogen-fixing endosymbiotic α-proteobacteria
Jiménez Zurdo, José I.
Riboregulation
sRNAs
Hfq
rhizobia
title_short Insights into the non-coding RNome of nitrogen-fixing endosymbiotic α-proteobacteria
title_full Insights into the non-coding RNome of nitrogen-fixing endosymbiotic α-proteobacteria
title_fullStr Insights into the non-coding RNome of nitrogen-fixing endosymbiotic α-proteobacteria
title_full_unstemmed Insights into the non-coding RNome of nitrogen-fixing endosymbiotic α-proteobacteria
title_sort Insights into the non-coding RNome of nitrogen-fixing endosymbiotic α-proteobacteria
dc.creator.none.fl_str_mv Jiménez Zurdo, José I.
Valverde, Claudio Fabián
Becker, Anke
author Jiménez Zurdo, José I.
author_facet Jiménez Zurdo, José I.
Valverde, Claudio Fabián
Becker, Anke
author_role author
author2 Valverde, Claudio Fabián
Becker, Anke
author2_role author
author
dc.subject.none.fl_str_mv Riboregulation
sRNAs
Hfq
rhizobia
topic Riboregulation
sRNAs
Hfq
rhizobia
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Symbiotic chronic infection of legumes by rhizobia involves transition of invading bacteria from a free-living environment in soil to an intracellular state as differentiated nitrogen-fixing bacteroids within the nodules elicited in the host plant. The adaptive flexibility demanded by this complex lifestyle is likely facilitated by the large set of regulatory proteins encoded by rhizobial genomes. However, proteins are not the only relevant players in the regulation of gene expression in bacteria. Large-scale high-throughput analysis of prokaryotic genomes is evidencing the expression of an unexpected plethora of small untranslated transcripts (sRNAs) with housekeeping or regulatory roles. sRNAs mostly act in response to environmental cues as post-transcriptional regulators of gene expression through protein-assisted base-pairing interactions with target mRNAs. Riboregulation contributes to fine-tune a wide range of bacterial processes which, in intracellular animal pathogens, largely compromise virulence traits. Here we summarize the incipient knowledge about the non-coding RNome structure of nitrogen-fixing endosymbiotic bacteria as inferred from genome-wide searches for sRNA genes in the alfalfa partner Sinorhizobium meliloti and further comparative genomics analysis. The biology of relevant S. meliloti RNA chaperones (e.g. Hfq) is also reviewed as a first global indicator of the impact of riboregulation in the establishment of the symbiotic interaction.
Fil: Jiménez Zurdo, José I.. Consejo Superior de Investigaciones Científicas. Estación Experimental del Zaidín; España
Fil: Valverde, Claudio Fabián. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Quilmes. Departamento de Ciencia y Tecnología; Argentina
Fil: Becker, Anke. Philipps-Universität Marburg; Alemania
description Symbiotic chronic infection of legumes by rhizobia involves transition of invading bacteria from a free-living environment in soil to an intracellular state as differentiated nitrogen-fixing bacteroids within the nodules elicited in the host plant. The adaptive flexibility demanded by this complex lifestyle is likely facilitated by the large set of regulatory proteins encoded by rhizobial genomes. However, proteins are not the only relevant players in the regulation of gene expression in bacteria. Large-scale high-throughput analysis of prokaryotic genomes is evidencing the expression of an unexpected plethora of small untranslated transcripts (sRNAs) with housekeeping or regulatory roles. sRNAs mostly act in response to environmental cues as post-transcriptional regulators of gene expression through protein-assisted base-pairing interactions with target mRNAs. Riboregulation contributes to fine-tune a wide range of bacterial processes which, in intracellular animal pathogens, largely compromise virulence traits. Here we summarize the incipient knowledge about the non-coding RNome structure of nitrogen-fixing endosymbiotic bacteria as inferred from genome-wide searches for sRNA genes in the alfalfa partner Sinorhizobium meliloti and further comparative genomics analysis. The biology of relevant S. meliloti RNA chaperones (e.g. Hfq) is also reviewed as a first global indicator of the impact of riboregulation in the establishment of the symbiotic interaction.
publishDate 2013
dc.date.none.fl_str_mv 2013-02
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/22744
Jiménez Zurdo, José I.; Valverde, Claudio Fabián; Becker, Anke; Insights into the non-coding RNome of nitrogen-fixing endosymbiotic α-proteobacteria; American Phytopathological Society; Molecular Plant-Microbe Interactions; 26; 2; 2-2013; 160-167
0894-0282
CONICET Digital
CONICET
url http://hdl.handle.net/11336/22744
identifier_str_mv Jiménez Zurdo, José I.; Valverde, Claudio Fabián; Becker, Anke; Insights into the non-coding RNome of nitrogen-fixing endosymbiotic α-proteobacteria; American Phytopathological Society; Molecular Plant-Microbe Interactions; 26; 2; 2-2013; 160-167
0894-0282
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://apsjournals.apsnet.org/loi/mpmi
info:eu-repo/semantics/altIdentifier/doi/10.1094/MPMI-07-12-0186-CR
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv American Phytopathological Society
publisher.none.fl_str_mv American Phytopathological Society
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.891075

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