Novel potential nanostructures for photodynamic therapy

Autores
Garcia, Pablo Facundo; Pérez, Luis Alberto; Coronado, Eduardo A.; Arguello, Gerardo
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Dimers could be very effective for generating photothermal damage because the excitation of the surface plasmon resonance (SPR) results in a temperature increase near the NP surface. In addition they present the advantage that the frequency of the SPR resonance can be tuned by using different NPs sizes or interparticle separations. The surface enhanced Raman scattering (SERS) response of the complex located in the gap of the NP aggregates results in an analytical SERS enhancement factor of 100,000. This feature corroborates that the ruthenium complex is indeed located between nanoparticles. An additional confirmation of this fact has been performed using Transmission Electron Microscopy (TEM), in which dimers, trimers and other aggregates where found. A kinetic study of the NP aggregation process, followed by the evolution of the UV vis extinction spectra, has been also performed. The results show that in a first stage it exist isolated NPs, later we can see the formation of dimers and trimers and in a third stage we observe NP-chains. We also perform fluorescence quenching experiments, finding Stern Volmer constants around Ksv = 4 × 1011 M−1. These constants involved a phenomenon called superquenching, which means a massive deactivation of the emission of the complex.
Fil: Garcia, Pablo Facundo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
Fil: Pérez, Luis Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
Fil: Coronado, Eduardo A.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
Fil: Arguello, Gerardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
Materia
Pdt
Gold
Nanoparticles
Plasmonics
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/47383
Acceder
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repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Novel potential nanostructures for photodynamic therapyGarcia, Pablo FacundoPérez, Luis AlbertoCoronado, Eduardo A.Arguello, GerardoPdtGoldNanoparticlesPlasmonicshttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1Dimers could be very effective for generating photothermal damage because the excitation of the surface plasmon resonance (SPR) results in a temperature increase near the NP surface. In addition they present the advantage that the frequency of the SPR resonance can be tuned by using different NPs sizes or interparticle separations. The surface enhanced Raman scattering (SERS) response of the complex located in the gap of the NP aggregates results in an analytical SERS enhancement factor of 100,000. This feature corroborates that the ruthenium complex is indeed located between nanoparticles. An additional confirmation of this fact has been performed using Transmission Electron Microscopy (TEM), in which dimers, trimers and other aggregates where found. A kinetic study of the NP aggregation process, followed by the evolution of the UV vis extinction spectra, has been also performed. The results show that in a first stage it exist isolated NPs, later we can see the formation of dimers and trimers and in a third stage we observe NP-chains. We also perform fluorescence quenching experiments, finding Stern Volmer constants around Ksv = 4 × 1011 M−1. These constants involved a phenomenon called superquenching, which means a massive deactivation of the emission of the complex.Fil: Garcia, Pablo Facundo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; ArgentinaFil: Pérez, Luis Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; ArgentinaFil: Coronado, Eduardo A.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; ArgentinaFil: Arguello, Gerardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; ArgentinaElsevier Science2015-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/47383Garcia, Pablo Facundo; Pérez, Luis Alberto; Coronado, Eduardo A.; Arguello, Gerardo; Novel potential nanostructures for photodynamic therapy; Elsevier Science; Photodiagnosis Photodynamic Therapy; 12; 3; 7-2015; 329-3291572-1000CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.pdpdt.2015.07.022info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T15:08:59Zoai:ri.conicet.gov.ar:11336/47383instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 15:09:00.16CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Novel potential nanostructures for photodynamic therapy
title Novel potential nanostructures for photodynamic therapy
spellingShingle Novel potential nanostructures for photodynamic therapy
Garcia, Pablo Facundo
Pdt
Gold
Nanoparticles
Plasmonics
title_short Novel potential nanostructures for photodynamic therapy
title_full Novel potential nanostructures for photodynamic therapy
title_fullStr Novel potential nanostructures for photodynamic therapy
title_full_unstemmed Novel potential nanostructures for photodynamic therapy
title_sort Novel potential nanostructures for photodynamic therapy
dc.creator.none.fl_str_mv Garcia, Pablo Facundo
Pérez, Luis Alberto
Coronado, Eduardo A.
Arguello, Gerardo
author Garcia, Pablo Facundo
author_facet Garcia, Pablo Facundo
Pérez, Luis Alberto
Coronado, Eduardo A.
Arguello, Gerardo
author_role author
author2 Pérez, Luis Alberto
Coronado, Eduardo A.
Arguello, Gerardo
author2_role author
author
author
dc.subject.none.fl_str_mv Pdt
Gold
Nanoparticles
Plasmonics
topic Pdt
Gold
Nanoparticles
Plasmonics
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Dimers could be very effective for generating photothermal damage because the excitation of the surface plasmon resonance (SPR) results in a temperature increase near the NP surface. In addition they present the advantage that the frequency of the SPR resonance can be tuned by using different NPs sizes or interparticle separations. The surface enhanced Raman scattering (SERS) response of the complex located in the gap of the NP aggregates results in an analytical SERS enhancement factor of 100,000. This feature corroborates that the ruthenium complex is indeed located between nanoparticles. An additional confirmation of this fact has been performed using Transmission Electron Microscopy (TEM), in which dimers, trimers and other aggregates where found. A kinetic study of the NP aggregation process, followed by the evolution of the UV vis extinction spectra, has been also performed. The results show that in a first stage it exist isolated NPs, later we can see the formation of dimers and trimers and in a third stage we observe NP-chains. We also perform fluorescence quenching experiments, finding Stern Volmer constants around Ksv = 4 × 1011 M−1. These constants involved a phenomenon called superquenching, which means a massive deactivation of the emission of the complex.
Fil: Garcia, Pablo Facundo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
Fil: Pérez, Luis Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina
Fil: Coronado, Eduardo A.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
Fil: Arguello, Gerardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
description Dimers could be very effective for generating photothermal damage because the excitation of the surface plasmon resonance (SPR) results in a temperature increase near the NP surface. In addition they present the advantage that the frequency of the SPR resonance can be tuned by using different NPs sizes or interparticle separations. The surface enhanced Raman scattering (SERS) response of the complex located in the gap of the NP aggregates results in an analytical SERS enhancement factor of 100,000. This feature corroborates that the ruthenium complex is indeed located between nanoparticles. An additional confirmation of this fact has been performed using Transmission Electron Microscopy (TEM), in which dimers, trimers and other aggregates where found. A kinetic study of the NP aggregation process, followed by the evolution of the UV vis extinction spectra, has been also performed. The results show that in a first stage it exist isolated NPs, later we can see the formation of dimers and trimers and in a third stage we observe NP-chains. We also perform fluorescence quenching experiments, finding Stern Volmer constants around Ksv = 4 × 1011 M−1. These constants involved a phenomenon called superquenching, which means a massive deactivation of the emission of the complex.
publishDate 2015
dc.date.none.fl_str_mv 2015-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/47383
Garcia, Pablo Facundo; Pérez, Luis Alberto; Coronado, Eduardo A.; Arguello, Gerardo; Novel potential nanostructures for photodynamic therapy; Elsevier Science; Photodiagnosis Photodynamic Therapy; 12; 3; 7-2015; 329-329
1572-1000
CONICET Digital
CONICET
url http://hdl.handle.net/11336/47383
identifier_str_mv Garcia, Pablo Facundo; Pérez, Luis Alberto; Coronado, Eduardo A.; Arguello, Gerardo; Novel potential nanostructures for photodynamic therapy; Elsevier Science; Photodiagnosis Photodynamic Therapy; 12; 3; 7-2015; 329-329
1572-1000
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.pdpdt.2015.07.022
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier Science
publisher.none.fl_str_mv Elsevier Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.22299

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