Electrochemical sensor for amino acids and glucose based on glassy carbon electrodes modified with multi-walled carbon nanotubes and copper microparticles dispersed in polyethyleni...

Autores: Gutierrez, Fabiana Andrea; Rubianes, María Dolores; Rivas, Gustavo Adolfo
Año de publicación: 2016
Idioma: inglés
Tipo de recurso: artículo
Estado: versión publicada
Descripción: This work reports the analytical performance of glassy carbon electrodes (GCE) modified with multi-walled carbon nanotubes (CNT) and copper microparticles dispersed in polyethylenimine (PEI) (GCE/CNT-PEI-Cu) for the quantification of amino acids, albumin and glucose. The best analytical performance was obtained with CNT-PEI-Cu prepared by sonicating for 15.0 min a mixture of 1.0 mg mL-1 PEI, 1.0 mg mL-1 CNT and 3.0 mg mL-1 copper microparticles. In the case of amino acids and albumin, the analytical signals were obtained from the increase of the copper oxidation signal produced as a consequence of the complex formation between Cu(II) and the amino acids. The sensor allowed the highly sensitive (submicromolar levels) and reproducible (3.9%) amperometric quantification of histidine, serine and cysteine at very low potentials (0.000 V) and pH 7.40. Albumin was quantified by Square Wave Voltammetry after 10.0 min interaction at - 0.100 V with detection limits of 1.2 mg mL-1. GCE/CNT-PEI-Cu was also used for the quantification of glucose by amperometry at 0.700 V in a 0.100 M sodium hydroxide solution through the known catalytic activity of copper towards the oxidation of glucose, with highly competitive detection limits (182 nM). GCE/CNT-PEI-Cu was successfully used for the quantification of amino acids and albumin in pharmaceutical products and carbohydrates in beverages.
Fil: Gutierrez, Fabiana Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
Fil: Rubianes, María Dolores. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
Fil: Rivas, Gustavo Adolfo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
Materia: Amino Acids
Carbon Nanotubes
Copper
Cysteine
Electrochemical Sensor
Glucose
Hystidine
Polyethylenimine
Serine
Nivel de accesibilidad: acceso abierto
Condiciones de uso: https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
Institución: Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador: oai:ri.conicet.gov.ar:11336/52592

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repository_id_str	3498
network_name_str	CONICET Digital (CONICET)
spelling	Electrochemical sensor for amino acids and glucose based on glassy carbon electrodes modified with multi-walled carbon nanotubes and copper microparticles dispersed in polyethylenimineGutierrez, Fabiana AndreaRubianes, María DoloresRivas, Gustavo AdolfoAmino AcidsCarbon NanotubesCopperCysteineElectrochemical SensorGlucoseHystidinePolyethylenimineSerinehttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1This work reports the analytical performance of glassy carbon electrodes (GCE) modified with multi-walled carbon nanotubes (CNT) and copper microparticles dispersed in polyethylenimine (PEI) (GCE/CNT-PEI-Cu) for the quantification of amino acids, albumin and glucose. The best analytical performance was obtained with CNT-PEI-Cu prepared by sonicating for 15.0 min a mixture of 1.0 mg mL-1 PEI, 1.0 mg mL-1 CNT and 3.0 mg mL-1 copper microparticles. In the case of amino acids and albumin, the analytical signals were obtained from the increase of the copper oxidation signal produced as a consequence of the complex formation between Cu(II) and the amino acids. The sensor allowed the highly sensitive (submicromolar levels) and reproducible (3.9%) amperometric quantification of histidine, serine and cysteine at very low potentials (0.000 V) and pH 7.40. Albumin was quantified by Square Wave Voltammetry after 10.0 min interaction at - 0.100 V with detection limits of 1.2 mg mL-1. GCE/CNT-PEI-Cu was also used for the quantification of glucose by amperometry at 0.700 V in a 0.100 M sodium hydroxide solution through the known catalytic activity of copper towards the oxidation of glucose, with highly competitive detection limits (182 nM). GCE/CNT-PEI-Cu was successfully used for the quantification of amino acids and albumin in pharmaceutical products and carbohydrates in beverages.Fil: Gutierrez, Fabiana Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; ArgentinaFil: Rubianes, María Dolores. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; ArgentinaFil: Rivas, Gustavo Adolfo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; ArgentinaElsevier Science Sa2016-03-15info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/52592Gutierrez, Fabiana Andrea; Rubianes, María Dolores; Rivas, Gustavo Adolfo; Electrochemical sensor for amino acids and glucose based on glassy carbon electrodes modified with multi-walled carbon nanotubes and copper microparticles dispersed in polyethylenimine; Elsevier Science Sa; Journal of Electroanalytical Chemistry; 765; 15-3-2016; 16-210022-07281572-6657CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S1572665715301685info:eu-repo/semantics/altIdentifier/doi/10.1016/j.jelechem.2015.10.029info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:13:31Zoai:ri.conicet.gov.ar:11336/52592instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:13:31.251CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv	Electrochemical sensor for amino acids and glucose based on glassy carbon electrodes modified with multi-walled carbon nanotubes and copper microparticles dispersed in polyethylenimine
title	Electrochemical sensor for amino acids and glucose based on glassy carbon electrodes modified with multi-walled carbon nanotubes and copper microparticles dispersed in polyethylenimine
spellingShingle	Electrochemical sensor for amino acids and glucose based on glassy carbon electrodes modified with multi-walled carbon nanotubes and copper microparticles dispersed in polyethylenimine Gutierrez, Fabiana Andrea Amino Acids Carbon Nanotubes Copper Cysteine Electrochemical Sensor Glucose Hystidine Polyethylenimine Serine
title_short	Electrochemical sensor for amino acids and glucose based on glassy carbon electrodes modified with multi-walled carbon nanotubes and copper microparticles dispersed in polyethylenimine
title_full	Electrochemical sensor for amino acids and glucose based on glassy carbon electrodes modified with multi-walled carbon nanotubes and copper microparticles dispersed in polyethylenimine
title_fullStr	Electrochemical sensor for amino acids and glucose based on glassy carbon electrodes modified with multi-walled carbon nanotubes and copper microparticles dispersed in polyethylenimine
title_full_unstemmed	Electrochemical sensor for amino acids and glucose based on glassy carbon electrodes modified with multi-walled carbon nanotubes and copper microparticles dispersed in polyethylenimine
title_sort	Electrochemical sensor for amino acids and glucose based on glassy carbon electrodes modified with multi-walled carbon nanotubes and copper microparticles dispersed in polyethylenimine
dc.creator.none.fl_str_mv	Gutierrez, Fabiana Andrea Rubianes, María Dolores Rivas, Gustavo Adolfo
author	Gutierrez, Fabiana Andrea
author_facet	Gutierrez, Fabiana Andrea Rubianes, María Dolores Rivas, Gustavo Adolfo
author_role	author
author2	Rubianes, María Dolores Rivas, Gustavo Adolfo
author2_role	author author
dc.subject.none.fl_str_mv	Amino Acids Carbon Nanotubes Copper Cysteine Electrochemical Sensor Glucose Hystidine Polyethylenimine Serine
topic	Amino Acids Carbon Nanotubes Copper Cysteine Electrochemical Sensor Glucose Hystidine Polyethylenimine Serine
purl_subject.fl_str_mv	https://purl.org/becyt/ford/1.4 https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv	This work reports the analytical performance of glassy carbon electrodes (GCE) modified with multi-walled carbon nanotubes (CNT) and copper microparticles dispersed in polyethylenimine (PEI) (GCE/CNT-PEI-Cu) for the quantification of amino acids, albumin and glucose. The best analytical performance was obtained with CNT-PEI-Cu prepared by sonicating for 15.0 min a mixture of 1.0 mg mL-1 PEI, 1.0 mg mL-1 CNT and 3.0 mg mL-1 copper microparticles. In the case of amino acids and albumin, the analytical signals were obtained from the increase of the copper oxidation signal produced as a consequence of the complex formation between Cu(II) and the amino acids. The sensor allowed the highly sensitive (submicromolar levels) and reproducible (3.9%) amperometric quantification of histidine, serine and cysteine at very low potentials (0.000 V) and pH 7.40. Albumin was quantified by Square Wave Voltammetry after 10.0 min interaction at - 0.100 V with detection limits of 1.2 mg mL-1. GCE/CNT-PEI-Cu was also used for the quantification of glucose by amperometry at 0.700 V in a 0.100 M sodium hydroxide solution through the known catalytic activity of copper towards the oxidation of glucose, with highly competitive detection limits (182 nM). GCE/CNT-PEI-Cu was successfully used for the quantification of amino acids and albumin in pharmaceutical products and carbohydrates in beverages. Fil: Gutierrez, Fabiana Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina Fil: Rubianes, María Dolores. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina Fil: Rivas, Gustavo Adolfo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; Argentina
description	This work reports the analytical performance of glassy carbon electrodes (GCE) modified with multi-walled carbon nanotubes (CNT) and copper microparticles dispersed in polyethylenimine (PEI) (GCE/CNT-PEI-Cu) for the quantification of amino acids, albumin and glucose. The best analytical performance was obtained with CNT-PEI-Cu prepared by sonicating for 15.0 min a mixture of 1.0 mg mL-1 PEI, 1.0 mg mL-1 CNT and 3.0 mg mL-1 copper microparticles. In the case of amino acids and albumin, the analytical signals were obtained from the increase of the copper oxidation signal produced as a consequence of the complex formation between Cu(II) and the amino acids. The sensor allowed the highly sensitive (submicromolar levels) and reproducible (3.9%) amperometric quantification of histidine, serine and cysteine at very low potentials (0.000 V) and pH 7.40. Albumin was quantified by Square Wave Voltammetry after 10.0 min interaction at - 0.100 V with detection limits of 1.2 mg mL-1. GCE/CNT-PEI-Cu was also used for the quantification of glucose by amperometry at 0.700 V in a 0.100 M sodium hydroxide solution through the known catalytic activity of copper towards the oxidation of glucose, with highly competitive detection limits (182 nM). GCE/CNT-PEI-Cu was successfully used for the quantification of amino acids and albumin in pharmaceutical products and carbohydrates in beverages.
publishDate	2016
dc.date.none.fl_str_mv	2016-03-15
dc.type.none.fl_str_mv	info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo
format	article
status_str	publishedVersion
dc.identifier.none.fl_str_mv	http://hdl.handle.net/11336/52592 Gutierrez, Fabiana Andrea; Rubianes, María Dolores; Rivas, Gustavo Adolfo; Electrochemical sensor for amino acids and glucose based on glassy carbon electrodes modified with multi-walled carbon nanotubes and copper microparticles dispersed in polyethylenimine; Elsevier Science Sa; Journal of Electroanalytical Chemistry; 765; 15-3-2016; 16-21 0022-0728 1572-6657 CONICET Digital CONICET
url	http://hdl.handle.net/11336/52592
identifier_str_mv	Gutierrez, Fabiana Andrea; Rubianes, María Dolores; Rivas, Gustavo Adolfo; Electrochemical sensor for amino acids and glucose based on glassy carbon electrodes modified with multi-walled carbon nanotubes and copper microparticles dispersed in polyethylenimine; Elsevier Science Sa; Journal of Electroanalytical Chemistry; 765; 15-3-2016; 16-21 0022-0728 1572-6657 CONICET Digital CONICET
dc.language.none.fl_str_mv	eng
language	eng
dc.relation.none.fl_str_mv	info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S1572665715301685 info:eu-repo/semantics/altIdentifier/doi/10.1016/j.jelechem.2015.10.029
dc.rights.none.fl_str_mv	info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv	openAccess
rights_invalid_str_mv	https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv	application/pdf application/pdf application/pdf
dc.publisher.none.fl_str_mv	Elsevier Science Sa
publisher.none.fl_str_mv	Elsevier Science Sa
dc.source.none.fl_str_mv	reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas
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repository.name.fl_str_mv	CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv	dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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Electrochemical sensor for amino acids and glucose based on glassy carbon electrodes modified with multi-walled carbon nanotubes and copper microparticles dispersed in polyethyleni...

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