A commentary on the interplay of biomaterials and cell adhesion: new insights in bone tissue regeneration

Autores
Gravina, Noel; D'elía, Noelia Laura; Benedini, Luciano Alejandro; Messina, Paula Verónica
Año de publicación
2024
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
This article navigates the relationship between biomaterials and osteogenic cell adhesion, highlighting theimportance of mimicking the physiological response for bone tissue regeneration. Within this spirit is an initialdescription of the interaction between osteoblasts and osteoprogenitor cells with the extracellular matrix, explainingthe leading role of integrins and cadherins in cell adhesion, and the intracellular signaling pathways elicited.Additionally, there is a focus on the strategies of advanced biomaterials that foster osteogenesis by replicating thenative environment, taking advantage of these known specific signaling pathways. The final remarks lay on the needfor careful consideration of in-vitro and in-vivo complexities in biomaterial development.
Fil: Gravina, Noel. Universidad Nacional del Sur. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; Argentina
Fil: D'elía, Noelia Laura. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; Argentina. Universidad Nacional del Sur. Departamento de Química; Argentina
Fil: Benedini, Luciano Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; Argentina
Fil: Messina, Paula Verónica. Universidad Nacional del Sur. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; Argentina
Materia
Osteogenesis
Cadherins
Integrins
Extracellular cell matrix
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/257689
Acceder
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network_name_str CONICET Digital (CONICET)
spelling A commentary on the interplay of biomaterials and cell adhesion: new insights in bone tissue regenerationGravina, NoelD'elía, Noelia LauraBenedini, Luciano AlejandroMessina, Paula VerónicaOsteogenesisCadherinsIntegrinsExtracellular cell matrixhttps://purl.org/becyt/ford/1.7https://purl.org/becyt/ford/1This article navigates the relationship between biomaterials and osteogenic cell adhesion, highlighting theimportance of mimicking the physiological response for bone tissue regeneration. Within this spirit is an initialdescription of the interaction between osteoblasts and osteoprogenitor cells with the extracellular matrix, explainingthe leading role of integrins and cadherins in cell adhesion, and the intracellular signaling pathways elicited.Additionally, there is a focus on the strategies of advanced biomaterials that foster osteogenesis by replicating thenative environment, taking advantage of these known specific signaling pathways. The final remarks lay on the needfor careful consideration of in-vitro and in-vivo complexities in biomaterial development.Fil: Gravina, Noel. Universidad Nacional del Sur. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; ArgentinaFil: D'elía, Noelia Laura. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; Argentina. Universidad Nacional del Sur. Departamento de Química; ArgentinaFil: Benedini, Luciano Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; ArgentinaFil: Messina, Paula Verónica. Universidad Nacional del Sur. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; ArgentinaTech Science Press2024-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/257689Gravina, Noel; D'elía, Noelia Laura; Benedini, Luciano Alejandro; Messina, Paula Verónica; A commentary on the interplay of biomaterials and cell adhesion: new insights in bone tissue regeneration; Tech Science Press; Biocell; 48; 11; 8-2024; 1517-15201667-5746CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.32604/biocell.2024.055513info:eu-repo/semantics/altIdentifier/url/https://www.techscience.com/biocell/v48n11/58595info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:18:47Zoai:ri.conicet.gov.ar:11336/257689instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:18:47.583CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv A commentary on the interplay of biomaterials and cell adhesion: new insights in bone tissue regeneration
title A commentary on the interplay of biomaterials and cell adhesion: new insights in bone tissue regeneration
spellingShingle A commentary on the interplay of biomaterials and cell adhesion: new insights in bone tissue regeneration
Gravina, Noel
Osteogenesis
Cadherins
Integrins
Extracellular cell matrix
title_short A commentary on the interplay of biomaterials and cell adhesion: new insights in bone tissue regeneration
title_full A commentary on the interplay of biomaterials and cell adhesion: new insights in bone tissue regeneration
title_fullStr A commentary on the interplay of biomaterials and cell adhesion: new insights in bone tissue regeneration
title_full_unstemmed A commentary on the interplay of biomaterials and cell adhesion: new insights in bone tissue regeneration
title_sort A commentary on the interplay of biomaterials and cell adhesion: new insights in bone tissue regeneration
dc.creator.none.fl_str_mv Gravina, Noel
D'elía, Noelia Laura
Benedini, Luciano Alejandro
Messina, Paula Verónica
author Gravina, Noel
author_facet Gravina, Noel
D'elía, Noelia Laura
Benedini, Luciano Alejandro
Messina, Paula Verónica
author_role author
author2 D'elía, Noelia Laura
Benedini, Luciano Alejandro
Messina, Paula Verónica
author2_role author
author
author
dc.subject.none.fl_str_mv Osteogenesis
Cadherins
Integrins
Extracellular cell matrix
topic Osteogenesis
Cadherins
Integrins
Extracellular cell matrix
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.7
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv This article navigates the relationship between biomaterials and osteogenic cell adhesion, highlighting theimportance of mimicking the physiological response for bone tissue regeneration. Within this spirit is an initialdescription of the interaction between osteoblasts and osteoprogenitor cells with the extracellular matrix, explainingthe leading role of integrins and cadherins in cell adhesion, and the intracellular signaling pathways elicited.Additionally, there is a focus on the strategies of advanced biomaterials that foster osteogenesis by replicating thenative environment, taking advantage of these known specific signaling pathways. The final remarks lay on the needfor careful consideration of in-vitro and in-vivo complexities in biomaterial development.
Fil: Gravina, Noel. Universidad Nacional del Sur. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; Argentina
Fil: D'elía, Noelia Laura. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; Argentina. Universidad Nacional del Sur. Departamento de Química; Argentina
Fil: Benedini, Luciano Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; Argentina
Fil: Messina, Paula Verónica. Universidad Nacional del Sur. Departamento de Química; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; Argentina
description This article navigates the relationship between biomaterials and osteogenic cell adhesion, highlighting theimportance of mimicking the physiological response for bone tissue regeneration. Within this spirit is an initialdescription of the interaction between osteoblasts and osteoprogenitor cells with the extracellular matrix, explainingthe leading role of integrins and cadherins in cell adhesion, and the intracellular signaling pathways elicited.Additionally, there is a focus on the strategies of advanced biomaterials that foster osteogenesis by replicating thenative environment, taking advantage of these known specific signaling pathways. The final remarks lay on the needfor careful consideration of in-vitro and in-vivo complexities in biomaterial development.
publishDate 2024
dc.date.none.fl_str_mv 2024-08
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/257689
Gravina, Noel; D'elía, Noelia Laura; Benedini, Luciano Alejandro; Messina, Paula Verónica; A commentary on the interplay of biomaterials and cell adhesion: new insights in bone tissue regeneration; Tech Science Press; Biocell; 48; 11; 8-2024; 1517-1520
1667-5746
CONICET Digital
CONICET
url http://hdl.handle.net/11336/257689
identifier_str_mv Gravina, Noel; D'elía, Noelia Laura; Benedini, Luciano Alejandro; Messina, Paula Verónica; A commentary on the interplay of biomaterials and cell adhesion: new insights in bone tissue regeneration; Tech Science Press; Biocell; 48; 11; 8-2024; 1517-1520
1667-5746
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.32604/biocell.2024.055513
info:eu-repo/semantics/altIdentifier/url/https://www.techscience.com/biocell/v48n11/58595
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Tech Science Press
publisher.none.fl_str_mv Tech Science Press
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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