Fluidized Bed Design Parameters Affecting Novel Lactic Acid Downstream Processing

Autores
Sosa, Ana V.; Córdoba, Pedro R.; Perotti, Nora Ines
Año de publicación
2001
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Lactic acid purification was directly done from fermentation utilizing a fluidized bed column refilled with a strong anionic exchange resin. The purpose of this work was to study the influence of two important design parameters, bed‐diameter (D) and bed‐height (H), in the lactic acid binding and elution capacity of the matrix. By changing the settled bed height from 2.5 to 5 cm for each diameter of column analyzed it was possible to obtain an 50% increase in the binding capacity of the resin in all experiments. This fact was attributed to a higher contact time between the culture broth and the anionic resin produced by the increase of back mixing and lactic acid residence time.
Fil: Sosa, Ana V.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Planta Piloto de Procesos Industriales Microbiológicos; Argentina
Fil: Córdoba, Pedro R.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Planta Piloto de Procesos Industriales Microbiológicos; Argentina
Fil: Perotti, Nora Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Planta Piloto de Procesos Industriales Microbiológicos; Argentina
Materia
Lactic Acid
Fluidized Bed
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/41698
Acceder
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network_acronym_str CONICETDig
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network_name_str CONICET Digital (CONICET)
spelling Fluidized Bed Design Parameters Affecting Novel Lactic Acid Downstream ProcessingSosa, Ana V.Córdoba, Pedro R.Perotti, Nora InesLactic AcidFluidized Bedhttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1Lactic acid purification was directly done from fermentation utilizing a fluidized bed column refilled with a strong anionic exchange resin. The purpose of this work was to study the influence of two important design parameters, bed‐diameter (D) and bed‐height (H), in the lactic acid binding and elution capacity of the matrix. By changing the settled bed height from 2.5 to 5 cm for each diameter of column analyzed it was possible to obtain an 50% increase in the binding capacity of the resin in all experiments. This fact was attributed to a higher contact time between the culture broth and the anionic resin produced by the increase of back mixing and lactic acid residence time.Fil: Sosa, Ana V.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Planta Piloto de Procesos Industriales Microbiológicos; ArgentinaFil: Córdoba, Pedro R.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Planta Piloto de Procesos Industriales Microbiológicos; ArgentinaFil: Perotti, Nora Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Planta Piloto de Procesos Industriales Microbiológicos; ArgentinaAmerican Chemical Society2001-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/41698Sosa, Ana V.; Córdoba, Pedro R.; Perotti, Nora Ines; Fluidized Bed Design Parameters Affecting Novel Lactic Acid Downstream Processing; American Chemical Society; Biotechnology Progress; 17; 6; 12-2001; 1079-10838756-7938CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1021/bp010089sinfo:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/abs/10.1021/bp010089sinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:08:09Zoai:ri.conicet.gov.ar:11336/41698instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:08:09.837CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Fluidized Bed Design Parameters Affecting Novel Lactic Acid Downstream Processing
title Fluidized Bed Design Parameters Affecting Novel Lactic Acid Downstream Processing
spellingShingle Fluidized Bed Design Parameters Affecting Novel Lactic Acid Downstream Processing
Sosa, Ana V.
Lactic Acid
Fluidized Bed
title_short Fluidized Bed Design Parameters Affecting Novel Lactic Acid Downstream Processing
title_full Fluidized Bed Design Parameters Affecting Novel Lactic Acid Downstream Processing
title_fullStr Fluidized Bed Design Parameters Affecting Novel Lactic Acid Downstream Processing
title_full_unstemmed Fluidized Bed Design Parameters Affecting Novel Lactic Acid Downstream Processing
title_sort Fluidized Bed Design Parameters Affecting Novel Lactic Acid Downstream Processing
dc.creator.none.fl_str_mv Sosa, Ana V.
Córdoba, Pedro R.
Perotti, Nora Ines
author Sosa, Ana V.
author_facet Sosa, Ana V.
Córdoba, Pedro R.
Perotti, Nora Ines
author_role author
author2 Córdoba, Pedro R.
Perotti, Nora Ines
author2_role author
author
dc.subject.none.fl_str_mv Lactic Acid
Fluidized Bed
topic Lactic Acid
Fluidized Bed
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Lactic acid purification was directly done from fermentation utilizing a fluidized bed column refilled with a strong anionic exchange resin. The purpose of this work was to study the influence of two important design parameters, bed‐diameter (D) and bed‐height (H), in the lactic acid binding and elution capacity of the matrix. By changing the settled bed height from 2.5 to 5 cm for each diameter of column analyzed it was possible to obtain an 50% increase in the binding capacity of the resin in all experiments. This fact was attributed to a higher contact time between the culture broth and the anionic resin produced by the increase of back mixing and lactic acid residence time.
Fil: Sosa, Ana V.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Planta Piloto de Procesos Industriales Microbiológicos; Argentina
Fil: Córdoba, Pedro R.. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Planta Piloto de Procesos Industriales Microbiológicos; Argentina
Fil: Perotti, Nora Ines. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Planta Piloto de Procesos Industriales Microbiológicos; Argentina
description Lactic acid purification was directly done from fermentation utilizing a fluidized bed column refilled with a strong anionic exchange resin. The purpose of this work was to study the influence of two important design parameters, bed‐diameter (D) and bed‐height (H), in the lactic acid binding and elution capacity of the matrix. By changing the settled bed height from 2.5 to 5 cm for each diameter of column analyzed it was possible to obtain an 50% increase in the binding capacity of the resin in all experiments. This fact was attributed to a higher contact time between the culture broth and the anionic resin produced by the increase of back mixing and lactic acid residence time.
publishDate 2001
dc.date.none.fl_str_mv 2001-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/41698
Sosa, Ana V.; Córdoba, Pedro R.; Perotti, Nora Ines; Fluidized Bed Design Parameters Affecting Novel Lactic Acid Downstream Processing; American Chemical Society; Biotechnology Progress; 17; 6; 12-2001; 1079-1083
8756-7938
CONICET Digital
CONICET
url http://hdl.handle.net/11336/41698
identifier_str_mv Sosa, Ana V.; Córdoba, Pedro R.; Perotti, Nora Ines; Fluidized Bed Design Parameters Affecting Novel Lactic Acid Downstream Processing; American Chemical Society; Biotechnology Progress; 17; 6; 12-2001; 1079-1083
8756-7938
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1021/bp010089s
info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/abs/10.1021/bp010089s
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv American Chemical Society
publisher.none.fl_str_mv American Chemical Society
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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