Single-step procedure for trace element determination in synovial fluid by dynamic reaction cell-inductively coupled plasma mass spectrometry

Autores
Moyano, Mario Franco; Verni, Ernesto Ricardo; Tamashiro, Héctor; Di Genaro, Maria Silvia; Martinez, Luis Dante; Gil, Raul Andres
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
A fast and single-step procedure for the dissolution of human synovial fluid in formic acid and further determination by dynamic reaction cell-inductively coupled plasma mass spectrometry (DRC-ICPMS) with a high-efficiency sample introduction system was developed. The samples were collected, treated and analyzed in the same screwcapped tubes. In order to overcome the effect of considerable carbon content, the sample introduction, nebulization and ICP operating conditions were carefully optimized. Furthermore, DRC technology with CH4 as reaction gas was used for the elimination of spectral interferences due to polyatomic ions. The effect of the sample matrix was evaluated and mitigated through comparison of direct calibration against aqueous standards, direct calibration in formic acid media and analyte addition calibration. The recommended procedure involved low dilution and low detection limits (from0.003 μg L−1 for U to 13.3 μg L−1 for Ti) with adequate precision (from 0.6% for Co to 6.6% for Ti). The proposedmethodwas successfully applied to determine 16 trace elements in concentrations from 0.03 μg L−1 (Cd) to 88.2 μg L−1 (Cu) in human synovial fluid samples.
Fil: Moyano, Mario Franco. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Química de San Luis; Argentina
Fil: Verni, Ernesto Ricardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Química de San Luis; Argentina
Fil: Tamashiro, Héctor. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto Multidisciplinario de Investigaciones Biológicas de San Luis; Argentina
Fil: Di Genaro, Maria Silvia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto Multidisciplinario de Investigaciones Biológicas de San Luis; Argentina
Fil: Martinez, Luis Dante. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Química de San Luis; Argentina
Fil: Gil, Raul Andres. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Química de San Luis; Argentina
Materia
Trace Elements
Human Synovial Fluid
Human Synovial Fluid Formic Acid Solubilization
High Efficiency Sample Introduction Drc-Icpms
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/7493
Acceder
id CONICETDig_0917aacd07b0be1990d6176ddbeeb73a
oai_identifier_str oai:ri.conicet.gov.ar:11336/7493
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Single-step procedure for trace element determination in synovial fluid by dynamic reaction cell-inductively coupled plasma mass spectrometryMoyano, Mario FrancoVerni, Ernesto RicardoTamashiro, HéctorDi Genaro, Maria SilviaMartinez, Luis DanteGil, Raul AndresTrace ElementsHuman Synovial FluidHuman Synovial Fluid Formic Acid SolubilizationHigh Efficiency Sample Introduction Drc-Icpmshttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1A fast and single-step procedure for the dissolution of human synovial fluid in formic acid and further determination by dynamic reaction cell-inductively coupled plasma mass spectrometry (DRC-ICPMS) with a high-efficiency sample introduction system was developed. The samples were collected, treated and analyzed in the same screwcapped tubes. In order to overcome the effect of considerable carbon content, the sample introduction, nebulization and ICP operating conditions were carefully optimized. Furthermore, DRC technology with CH4 as reaction gas was used for the elimination of spectral interferences due to polyatomic ions. The effect of the sample matrix was evaluated and mitigated through comparison of direct calibration against aqueous standards, direct calibration in formic acid media and analyte addition calibration. The recommended procedure involved low dilution and low detection limits (from0.003 μg L−1 for U to 13.3 μg L−1 for Ti) with adequate precision (from 0.6% for Co to 6.6% for Ti). The proposedmethodwas successfully applied to determine 16 trace elements in concentrations from 0.03 μg L−1 (Cd) to 88.2 μg L−1 (Cu) in human synovial fluid samples.Fil: Moyano, Mario Franco. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Química de San Luis; ArgentinaFil: Verni, Ernesto Ricardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Química de San Luis; ArgentinaFil: Tamashiro, Héctor. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto Multidisciplinario de Investigaciones Biológicas de San Luis; ArgentinaFil: Di Genaro, Maria Silvia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto Multidisciplinario de Investigaciones Biológicas de San Luis; ArgentinaFil: Martinez, Luis Dante. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Química de San Luis; ArgentinaFil: Gil, Raul Andres. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Química de San Luis; ArgentinaElsevier2014-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/7493Moyano, Mario Franco; Verni, Ernesto Ricardo; Tamashiro, Héctor; Di Genaro, Maria Silvia; Martinez, Luis Dante; et al.; Single-step procedure for trace element determination in synovial fluid by dynamic reaction cell-inductively coupled plasma mass spectrometry; Elsevier; Microchemical Journal; 112; 2-2014; 17-240026-265Xenginfo:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0026265X13001707info:eu-repo/semantics/altIdentifier/doi/10.1016/j.microc.2013.09.015info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:16:31Zoai:ri.conicet.gov.ar:11336/7493instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:16:32.232CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Single-step procedure for trace element determination in synovial fluid by dynamic reaction cell-inductively coupled plasma mass spectrometry
title Single-step procedure for trace element determination in synovial fluid by dynamic reaction cell-inductively coupled plasma mass spectrometry
spellingShingle Single-step procedure for trace element determination in synovial fluid by dynamic reaction cell-inductively coupled plasma mass spectrometry
Moyano, Mario Franco
Trace Elements
Human Synovial Fluid
Human Synovial Fluid Formic Acid Solubilization
High Efficiency Sample Introduction Drc-Icpms
title_short Single-step procedure for trace element determination in synovial fluid by dynamic reaction cell-inductively coupled plasma mass spectrometry
title_full Single-step procedure for trace element determination in synovial fluid by dynamic reaction cell-inductively coupled plasma mass spectrometry
title_fullStr Single-step procedure for trace element determination in synovial fluid by dynamic reaction cell-inductively coupled plasma mass spectrometry
title_full_unstemmed Single-step procedure for trace element determination in synovial fluid by dynamic reaction cell-inductively coupled plasma mass spectrometry
title_sort Single-step procedure for trace element determination in synovial fluid by dynamic reaction cell-inductively coupled plasma mass spectrometry
dc.creator.none.fl_str_mv Moyano, Mario Franco
Verni, Ernesto Ricardo
Tamashiro, Héctor
Di Genaro, Maria Silvia
Martinez, Luis Dante
Gil, Raul Andres
author Moyano, Mario Franco
author_facet Moyano, Mario Franco
Verni, Ernesto Ricardo
Tamashiro, Héctor
Di Genaro, Maria Silvia
Martinez, Luis Dante
Gil, Raul Andres
author_role author
author2 Verni, Ernesto Ricardo
Tamashiro, Héctor
Di Genaro, Maria Silvia
Martinez, Luis Dante
Gil, Raul Andres
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Trace Elements
Human Synovial Fluid
Human Synovial Fluid Formic Acid Solubilization
High Efficiency Sample Introduction Drc-Icpms
topic Trace Elements
Human Synovial Fluid
Human Synovial Fluid Formic Acid Solubilization
High Efficiency Sample Introduction Drc-Icpms
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv A fast and single-step procedure for the dissolution of human synovial fluid in formic acid and further determination by dynamic reaction cell-inductively coupled plasma mass spectrometry (DRC-ICPMS) with a high-efficiency sample introduction system was developed. The samples were collected, treated and analyzed in the same screwcapped tubes. In order to overcome the effect of considerable carbon content, the sample introduction, nebulization and ICP operating conditions were carefully optimized. Furthermore, DRC technology with CH4 as reaction gas was used for the elimination of spectral interferences due to polyatomic ions. The effect of the sample matrix was evaluated and mitigated through comparison of direct calibration against aqueous standards, direct calibration in formic acid media and analyte addition calibration. The recommended procedure involved low dilution and low detection limits (from0.003 μg L−1 for U to 13.3 μg L−1 for Ti) with adequate precision (from 0.6% for Co to 6.6% for Ti). The proposedmethodwas successfully applied to determine 16 trace elements in concentrations from 0.03 μg L−1 (Cd) to 88.2 μg L−1 (Cu) in human synovial fluid samples.
Fil: Moyano, Mario Franco. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Química de San Luis; Argentina
Fil: Verni, Ernesto Ricardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Química de San Luis; Argentina
Fil: Tamashiro, Héctor. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto Multidisciplinario de Investigaciones Biológicas de San Luis; Argentina
Fil: Di Genaro, Maria Silvia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto Multidisciplinario de Investigaciones Biológicas de San Luis; Argentina
Fil: Martinez, Luis Dante. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Química de San Luis; Argentina
Fil: Gil, Raul Andres. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Química de San Luis; Argentina
description A fast and single-step procedure for the dissolution of human synovial fluid in formic acid and further determination by dynamic reaction cell-inductively coupled plasma mass spectrometry (DRC-ICPMS) with a high-efficiency sample introduction system was developed. The samples were collected, treated and analyzed in the same screwcapped tubes. In order to overcome the effect of considerable carbon content, the sample introduction, nebulization and ICP operating conditions were carefully optimized. Furthermore, DRC technology with CH4 as reaction gas was used for the elimination of spectral interferences due to polyatomic ions. The effect of the sample matrix was evaluated and mitigated through comparison of direct calibration against aqueous standards, direct calibration in formic acid media and analyte addition calibration. The recommended procedure involved low dilution and low detection limits (from0.003 μg L−1 for U to 13.3 μg L−1 for Ti) with adequate precision (from 0.6% for Co to 6.6% for Ti). The proposedmethodwas successfully applied to determine 16 trace elements in concentrations from 0.03 μg L−1 (Cd) to 88.2 μg L−1 (Cu) in human synovial fluid samples.
publishDate 2014
dc.date.none.fl_str_mv 2014-02
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/7493
Moyano, Mario Franco; Verni, Ernesto Ricardo; Tamashiro, Héctor; Di Genaro, Maria Silvia; Martinez, Luis Dante; et al.; Single-step procedure for trace element determination in synovial fluid by dynamic reaction cell-inductively coupled plasma mass spectrometry; Elsevier; Microchemical Journal; 112; 2-2014; 17-24
0026-265X
url http://hdl.handle.net/11336/7493
identifier_str_mv Moyano, Mario Franco; Verni, Ernesto Ricardo; Tamashiro, Héctor; Di Genaro, Maria Silvia; Martinez, Luis Dante; et al.; Single-step procedure for trace element determination in synovial fluid by dynamic reaction cell-inductively coupled plasma mass spectrometry; Elsevier; Microchemical Journal; 112; 2-2014; 17-24
0026-265X
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0026265X13001707
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.microc.2013.09.015
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1844614111110889472
score 13.070432

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