Neuroprotection in metabolic syndrome by environmental enrichment. A lifespan perspective

Autores
Kobiec, Tamara; Mardaraz, Claudia; Toro Urrego, Nicolas; Kolliker Frers, Rodolfo Alberto; Capani, Francisco; Otero losada, Matilde Estela
Año de publicación
2023
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Metabolic syndrome (MetS) is defined by the concurrence of different metabolic conditions: obesity, hypertension, dyslipidemia, and hyperglycemia. Its incidence has been increasingly rising over the past decades and has become a global health problem. MetS has deleterious consequences on the central nervous system (CNS) and neurological development. MetS can last several years or be lifelong, affecting the CNS in different ways and treatments can help manage condition, though there is no known cure. The early childhood years are extremely important in neurodevelopment, which extends beyond, encompassing a lifetime. Neuroplastic changes take place all life through — childhood, adolescence, adulthood, and old age — are highly sensitive to environmental input. Environmental factors have an important role in the etiopathogenesis and treatment of MetS, so environmental enrichment (EE) stands as a promising non-invasive therapeutic approach. While the EE paradigm has been designed for animal housing, its principles can be and actually are applied in cognitive, sensory, social, and physical stimulation programs for humans. Here, we briefly review the central milestones in neurodevelopment at each life stage, along with the research studies carried out on how MetS affects neurodevelopment at each life stage and the contributions that EE models can provide to improve health over the lifespan.
Fil: Kobiec, Tamara. Universidad Abierta Interamericana; Argentina. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Mardaraz, Claudia. Universidad Abierta Interamericana; Argentina
Fil: Toro Urrego, Nicolas. Universidad Abierta Interamericana; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Kolliker Frers, Rodolfo Alberto. Universidad Abierta Interamericana; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Capani, Francisco. Universidad Abierta Interamericana; Argentina. Universidad Argentina "John F. Kennedy"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; Argentina
Fil: Otero losada, Matilde Estela. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Abierta Interamericana; Argentina
Materia
ENVIRONMENTAL ENRICHMENT
HEALTHSPAN
LIFESPAN
METABOLIC SYNDROME
NEURODEVELOPMENT
NEUROPROTECTION
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/220722
Acceder
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repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Neuroprotection in metabolic syndrome by environmental enrichment. A lifespan perspectiveKobiec, TamaraMardaraz, ClaudiaToro Urrego, NicolasKolliker Frers, Rodolfo AlbertoCapani, FranciscoOtero losada, Matilde EstelaENVIRONMENTAL ENRICHMENTHEALTHSPANLIFESPANMETABOLIC SYNDROMENEURODEVELOPMENTNEUROPROTECTIONhttps://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3Metabolic syndrome (MetS) is defined by the concurrence of different metabolic conditions: obesity, hypertension, dyslipidemia, and hyperglycemia. Its incidence has been increasingly rising over the past decades and has become a global health problem. MetS has deleterious consequences on the central nervous system (CNS) and neurological development. MetS can last several years or be lifelong, affecting the CNS in different ways and treatments can help manage condition, though there is no known cure. The early childhood years are extremely important in neurodevelopment, which extends beyond, encompassing a lifetime. Neuroplastic changes take place all life through — childhood, adolescence, adulthood, and old age — are highly sensitive to environmental input. Environmental factors have an important role in the etiopathogenesis and treatment of MetS, so environmental enrichment (EE) stands as a promising non-invasive therapeutic approach. While the EE paradigm has been designed for animal housing, its principles can be and actually are applied in cognitive, sensory, social, and physical stimulation programs for humans. Here, we briefly review the central milestones in neurodevelopment at each life stage, along with the research studies carried out on how MetS affects neurodevelopment at each life stage and the contributions that EE models can provide to improve health over the lifespan.Fil: Kobiec, Tamara. Universidad Abierta Interamericana; Argentina. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Mardaraz, Claudia. Universidad Abierta Interamericana; ArgentinaFil: Toro Urrego, Nicolas. Universidad Abierta Interamericana; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Kolliker Frers, Rodolfo Alberto. Universidad Abierta Interamericana; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Capani, Francisco. Universidad Abierta Interamericana; Argentina. Universidad Argentina "John F. Kennedy"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; ArgentinaFil: Otero losada, Matilde Estela. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Abierta Interamericana; ArgentinaFrontiers Media2023-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/220722Kobiec, Tamara; Mardaraz, Claudia; Toro Urrego, Nicolas; Kolliker Frers, Rodolfo Alberto; Capani, Francisco; et al.; Neuroprotection in metabolic syndrome by environmental enrichment. A lifespan perspective; Frontiers Media; Frontiers in Neuroscience; 17; 8-2023; 1-271662-45481662-453XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.3389/fnins.2023.1214468info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:57:33Zoai:ri.conicet.gov.ar:11336/220722instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:57:33.957CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Neuroprotection in metabolic syndrome by environmental enrichment. A lifespan perspective
title Neuroprotection in metabolic syndrome by environmental enrichment. A lifespan perspective
spellingShingle Neuroprotection in metabolic syndrome by environmental enrichment. A lifespan perspective
Kobiec, Tamara
ENVIRONMENTAL ENRICHMENT
HEALTHSPAN
LIFESPAN
METABOLIC SYNDROME
NEURODEVELOPMENT
NEUROPROTECTION
title_short Neuroprotection in metabolic syndrome by environmental enrichment. A lifespan perspective
title_full Neuroprotection in metabolic syndrome by environmental enrichment. A lifespan perspective
title_fullStr Neuroprotection in metabolic syndrome by environmental enrichment. A lifespan perspective
title_full_unstemmed Neuroprotection in metabolic syndrome by environmental enrichment. A lifespan perspective
title_sort Neuroprotection in metabolic syndrome by environmental enrichment. A lifespan perspective
dc.creator.none.fl_str_mv Kobiec, Tamara
Mardaraz, Claudia
Toro Urrego, Nicolas
Kolliker Frers, Rodolfo Alberto
Capani, Francisco
Otero losada, Matilde Estela
author Kobiec, Tamara
author_facet Kobiec, Tamara
Mardaraz, Claudia
Toro Urrego, Nicolas
Kolliker Frers, Rodolfo Alberto
Capani, Francisco
Otero losada, Matilde Estela
author_role author
author2 Mardaraz, Claudia
Toro Urrego, Nicolas
Kolliker Frers, Rodolfo Alberto
Capani, Francisco
Otero losada, Matilde Estela
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv ENVIRONMENTAL ENRICHMENT
HEALTHSPAN
LIFESPAN
METABOLIC SYNDROME
NEURODEVELOPMENT
NEUROPROTECTION
topic ENVIRONMENTAL ENRICHMENT
HEALTHSPAN
LIFESPAN
METABOLIC SYNDROME
NEURODEVELOPMENT
NEUROPROTECTION
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Metabolic syndrome (MetS) is defined by the concurrence of different metabolic conditions: obesity, hypertension, dyslipidemia, and hyperglycemia. Its incidence has been increasingly rising over the past decades and has become a global health problem. MetS has deleterious consequences on the central nervous system (CNS) and neurological development. MetS can last several years or be lifelong, affecting the CNS in different ways and treatments can help manage condition, though there is no known cure. The early childhood years are extremely important in neurodevelopment, which extends beyond, encompassing a lifetime. Neuroplastic changes take place all life through — childhood, adolescence, adulthood, and old age — are highly sensitive to environmental input. Environmental factors have an important role in the etiopathogenesis and treatment of MetS, so environmental enrichment (EE) stands as a promising non-invasive therapeutic approach. While the EE paradigm has been designed for animal housing, its principles can be and actually are applied in cognitive, sensory, social, and physical stimulation programs for humans. Here, we briefly review the central milestones in neurodevelopment at each life stage, along with the research studies carried out on how MetS affects neurodevelopment at each life stage and the contributions that EE models can provide to improve health over the lifespan.
Fil: Kobiec, Tamara. Universidad Abierta Interamericana; Argentina. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Mardaraz, Claudia. Universidad Abierta Interamericana; Argentina
Fil: Toro Urrego, Nicolas. Universidad Abierta Interamericana; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Kolliker Frers, Rodolfo Alberto. Universidad Abierta Interamericana; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Capani, Francisco. Universidad Abierta Interamericana; Argentina. Universidad Argentina "John F. Kennedy"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; Argentina
Fil: Otero losada, Matilde Estela. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Abierta Interamericana; Argentina
description Metabolic syndrome (MetS) is defined by the concurrence of different metabolic conditions: obesity, hypertension, dyslipidemia, and hyperglycemia. Its incidence has been increasingly rising over the past decades and has become a global health problem. MetS has deleterious consequences on the central nervous system (CNS) and neurological development. MetS can last several years or be lifelong, affecting the CNS in different ways and treatments can help manage condition, though there is no known cure. The early childhood years are extremely important in neurodevelopment, which extends beyond, encompassing a lifetime. Neuroplastic changes take place all life through — childhood, adolescence, adulthood, and old age — are highly sensitive to environmental input. Environmental factors have an important role in the etiopathogenesis and treatment of MetS, so environmental enrichment (EE) stands as a promising non-invasive therapeutic approach. While the EE paradigm has been designed for animal housing, its principles can be and actually are applied in cognitive, sensory, social, and physical stimulation programs for humans. Here, we briefly review the central milestones in neurodevelopment at each life stage, along with the research studies carried out on how MetS affects neurodevelopment at each life stage and the contributions that EE models can provide to improve health over the lifespan.
publishDate 2023
dc.date.none.fl_str_mv 2023-08
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/220722
Kobiec, Tamara; Mardaraz, Claudia; Toro Urrego, Nicolas; Kolliker Frers, Rodolfo Alberto; Capani, Francisco; et al.; Neuroprotection in metabolic syndrome by environmental enrichment. A lifespan perspective; Frontiers Media; Frontiers in Neuroscience; 17; 8-2023; 1-27
1662-4548
1662-453X
CONICET Digital
CONICET
url http://hdl.handle.net/11336/220722
identifier_str_mv Kobiec, Tamara; Mardaraz, Claudia; Toro Urrego, Nicolas; Kolliker Frers, Rodolfo Alberto; Capani, Francisco; et al.; Neuroprotection in metabolic syndrome by environmental enrichment. A lifespan perspective; Frontiers Media; Frontiers in Neuroscience; 17; 8-2023; 1-27
1662-4548
1662-453X
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.3389/fnins.2023.1214468
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Frontiers Media
publisher.none.fl_str_mv Frontiers Media
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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