Bioresorbable poly(ester-ether urethane)s fromL-lysine diisocyanate and triblock copolymers with different hydrophilic character

Autores
Abraham, Gustavo Abel; Marcos Fernández, Angél; San Román, Julio
Año de publicación
2006
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Bioresorbable linear poly(ester‐ether urethane)s with different hydrophilic character were synthesized from block copolymers of poly(ϵ‐caprolactone)‐poly(ethylene oxide)‐poly(ϵ‐caprolactone) (PCL‐PEO‐PCL) as macrodiols, and L‐lysine diisocyanate (LDI). A series of PCL‐PEO‐PCL triblock copolymers with different PEO and PCL chain length was obtained by reacting PEO with ϵ‐caprolactone. Polyurethanes were synthesized by reacting the triblock copolymers with LDI in solution using stannous 2‐ethylhexanoate as catalyst. The prepared triblock copolymers and polyurethanes were fully characterized by proton nuclear magnetic resonance spectroscopy, size exclusion chromatography, differential scanning calorimetry, and wide‐angle X‐ray diffraction. Water uptake, hydrolytic stability, and tensile properties of polyurethanes with different composition were evaluated and discussed in terms of the chain length and molecular weight of the polymers and its block components. Water uptake seems to depend on the ethylene oxide unit content of the polyurethane regardless of the triblock structure. Mechanical properties of the synthesized polymers were strongly affected by the molecular weight achieved during polymerization. The use of triblock macrodiols with different hydrophilicity allowed the preparation of a series of polyurethanes having a broad range of properties
Fil: Abraham, Gustavo Abel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; Argentina
Fil: Marcos Fernández, Angél. Instituto en Ciencia y Tecnología de Polímeros; España
Fil: San Román, Julio. Instituto en Ciencia y Tecnología de Polímeros; España
Materia
Polyurethanes
Biomedical Polymers
Macrodiols
Bioresorbable Polyurethanes
Lysine Diisocyanate
Triblock Copolymers
Poly(Ethylene Oxide)
Poly( -Caprolactone)
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/41689
Acceder
id CONICETDig_02691a007aa6e7ec6084205711c43285
oai_identifier_str oai:ri.conicet.gov.ar:11336/41689
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Bioresorbable poly(ester-ether urethane)s fromL-lysine diisocyanate and triblock copolymers with different hydrophilic characterAbraham, Gustavo AbelMarcos Fernández, AngélSan Román, JulioPolyurethanesBiomedical PolymersMacrodiolsBioresorbable PolyurethanesLysine DiisocyanateTriblock CopolymersPoly(Ethylene Oxide)Poly( -Caprolactone)https://purl.org/becyt/ford/3.4https://purl.org/becyt/ford/3https://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1Bioresorbable linear poly(ester‐ether urethane)s with different hydrophilic character were synthesized from block copolymers of poly(ϵ‐caprolactone)‐poly(ethylene oxide)‐poly(ϵ‐caprolactone) (PCL‐PEO‐PCL) as macrodiols, and L‐lysine diisocyanate (LDI). A series of PCL‐PEO‐PCL triblock copolymers with different PEO and PCL chain length was obtained by reacting PEO with ϵ‐caprolactone. Polyurethanes were synthesized by reacting the triblock copolymers with LDI in solution using stannous 2‐ethylhexanoate as catalyst. The prepared triblock copolymers and polyurethanes were fully characterized by proton nuclear magnetic resonance spectroscopy, size exclusion chromatography, differential scanning calorimetry, and wide‐angle X‐ray diffraction. Water uptake, hydrolytic stability, and tensile properties of polyurethanes with different composition were evaluated and discussed in terms of the chain length and molecular weight of the polymers and its block components. Water uptake seems to depend on the ethylene oxide unit content of the polyurethane regardless of the triblock structure. Mechanical properties of the synthesized polymers were strongly affected by the molecular weight achieved during polymerization. The use of triblock macrodiols with different hydrophilicity allowed the preparation of a series of polyurethanes having a broad range of propertiesFil: Abraham, Gustavo Abel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; ArgentinaFil: Marcos Fernández, Angél. Instituto en Ciencia y Tecnología de Polímeros; EspañaFil: San Román, Julio. Instituto en Ciencia y Tecnología de Polímeros; EspañaWiley-liss, Div John Wiley & Sons Inc2006-03-29info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/41689Abraham, Gustavo Abel; Marcos Fernández, Angél; San Román, Julio; Bioresorbable poly(ester-ether urethane)s fromL-lysine diisocyanate and triblock copolymers with different hydrophilic character; Wiley-liss, Div John Wiley & Sons Inc; Journal of Biomedical Materials Research Part A; 76A; 4; 29-3-2006; 729-7361549-3296CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/pdf/10.1002/jbm.a.30540info:eu-repo/semantics/altIdentifier/doi/10.1002/jbm.a.30540info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:11:19Zoai:ri.conicet.gov.ar:11336/41689instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:11:19.788CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Bioresorbable poly(ester-ether urethane)s fromL-lysine diisocyanate and triblock copolymers with different hydrophilic character
title Bioresorbable poly(ester-ether urethane)s fromL-lysine diisocyanate and triblock copolymers with different hydrophilic character
spellingShingle Bioresorbable poly(ester-ether urethane)s fromL-lysine diisocyanate and triblock copolymers with different hydrophilic character
Abraham, Gustavo Abel
Polyurethanes
Biomedical Polymers
Macrodiols
Bioresorbable Polyurethanes
Lysine Diisocyanate
Triblock Copolymers
Poly(Ethylene Oxide)
Poly( -Caprolactone)
title_short Bioresorbable poly(ester-ether urethane)s fromL-lysine diisocyanate and triblock copolymers with different hydrophilic character
title_full Bioresorbable poly(ester-ether urethane)s fromL-lysine diisocyanate and triblock copolymers with different hydrophilic character
title_fullStr Bioresorbable poly(ester-ether urethane)s fromL-lysine diisocyanate and triblock copolymers with different hydrophilic character
title_full_unstemmed Bioresorbable poly(ester-ether urethane)s fromL-lysine diisocyanate and triblock copolymers with different hydrophilic character
title_sort Bioresorbable poly(ester-ether urethane)s fromL-lysine diisocyanate and triblock copolymers with different hydrophilic character
dc.creator.none.fl_str_mv Abraham, Gustavo Abel
Marcos Fernández, Angél
San Román, Julio
author Abraham, Gustavo Abel
author_facet Abraham, Gustavo Abel
Marcos Fernández, Angél
San Román, Julio
author_role author
author2 Marcos Fernández, Angél
San Román, Julio
author2_role author
author
dc.subject.none.fl_str_mv Polyurethanes
Biomedical Polymers
Macrodiols
Bioresorbable Polyurethanes
Lysine Diisocyanate
Triblock Copolymers
Poly(Ethylene Oxide)
Poly( -Caprolactone)
topic Polyurethanes
Biomedical Polymers
Macrodiols
Bioresorbable Polyurethanes
Lysine Diisocyanate
Triblock Copolymers
Poly(Ethylene Oxide)
Poly( -Caprolactone)
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.4
https://purl.org/becyt/ford/3
https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Bioresorbable linear poly(ester‐ether urethane)s with different hydrophilic character were synthesized from block copolymers of poly(ϵ‐caprolactone)‐poly(ethylene oxide)‐poly(ϵ‐caprolactone) (PCL‐PEO‐PCL) as macrodiols, and L‐lysine diisocyanate (LDI). A series of PCL‐PEO‐PCL triblock copolymers with different PEO and PCL chain length was obtained by reacting PEO with ϵ‐caprolactone. Polyurethanes were synthesized by reacting the triblock copolymers with LDI in solution using stannous 2‐ethylhexanoate as catalyst. The prepared triblock copolymers and polyurethanes were fully characterized by proton nuclear magnetic resonance spectroscopy, size exclusion chromatography, differential scanning calorimetry, and wide‐angle X‐ray diffraction. Water uptake, hydrolytic stability, and tensile properties of polyurethanes with different composition were evaluated and discussed in terms of the chain length and molecular weight of the polymers and its block components. Water uptake seems to depend on the ethylene oxide unit content of the polyurethane regardless of the triblock structure. Mechanical properties of the synthesized polymers were strongly affected by the molecular weight achieved during polymerization. The use of triblock macrodiols with different hydrophilicity allowed the preparation of a series of polyurethanes having a broad range of properties
Fil: Abraham, Gustavo Abel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; Argentina
Fil: Marcos Fernández, Angél. Instituto en Ciencia y Tecnología de Polímeros; España
Fil: San Román, Julio. Instituto en Ciencia y Tecnología de Polímeros; España
description Bioresorbable linear poly(ester‐ether urethane)s with different hydrophilic character were synthesized from block copolymers of poly(ϵ‐caprolactone)‐poly(ethylene oxide)‐poly(ϵ‐caprolactone) (PCL‐PEO‐PCL) as macrodiols, and L‐lysine diisocyanate (LDI). A series of PCL‐PEO‐PCL triblock copolymers with different PEO and PCL chain length was obtained by reacting PEO with ϵ‐caprolactone. Polyurethanes were synthesized by reacting the triblock copolymers with LDI in solution using stannous 2‐ethylhexanoate as catalyst. The prepared triblock copolymers and polyurethanes were fully characterized by proton nuclear magnetic resonance spectroscopy, size exclusion chromatography, differential scanning calorimetry, and wide‐angle X‐ray diffraction. Water uptake, hydrolytic stability, and tensile properties of polyurethanes with different composition were evaluated and discussed in terms of the chain length and molecular weight of the polymers and its block components. Water uptake seems to depend on the ethylene oxide unit content of the polyurethane regardless of the triblock structure. Mechanical properties of the synthesized polymers were strongly affected by the molecular weight achieved during polymerization. The use of triblock macrodiols with different hydrophilicity allowed the preparation of a series of polyurethanes having a broad range of properties
publishDate 2006
dc.date.none.fl_str_mv 2006-03-29
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/41689
Abraham, Gustavo Abel; Marcos Fernández, Angél; San Román, Julio; Bioresorbable poly(ester-ether urethane)s fromL-lysine diisocyanate and triblock copolymers with different hydrophilic character; Wiley-liss, Div John Wiley & Sons Inc; Journal of Biomedical Materials Research Part A; 76A; 4; 29-3-2006; 729-736
1549-3296
CONICET Digital
CONICET
url http://hdl.handle.net/11336/41689
identifier_str_mv Abraham, Gustavo Abel; Marcos Fernández, Angél; San Román, Julio; Bioresorbable poly(ester-ether urethane)s fromL-lysine diisocyanate and triblock copolymers with different hydrophilic character; Wiley-liss, Div John Wiley & Sons Inc; Journal of Biomedical Materials Research Part A; 76A; 4; 29-3-2006; 729-736
1549-3296
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/pdf/10.1002/jbm.a.30540
info:eu-repo/semantics/altIdentifier/doi/10.1002/jbm.a.30540
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Wiley-liss, Div John Wiley & Sons Inc
publisher.none.fl_str_mv Wiley-liss, Div John Wiley & Sons Inc
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1844614011271774208
score 13.070432

Publicaciones similares