Multidrug resistance in Escherichia coli carrying integrons isolated from a pig farm with moderate antibiotic use

Autores
Torre, Eulalia de la; Colello, Rocío; Fernández, Daniel; Etcheverría, Analía Inés; Di Conza, José; Gutkind, Gabriel O.; Tapia, María Ofelia; Dieguez, Susana Nelly; Soraci, Alejandro Luis; Padola, Nora Lía
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The emergence and dissemination of antimicrobial resistance in bacteria derived from food-producing animals is a consequence of intensive agricultural and veterinary use of antimicrobial compounds. The inappropriate use and prescribing of antibiotics, along with their use as growth promoters, is the main cause of the development of resistance. The potential risk of the transfer of this resistance through the food chain by bacteria such as Escherichia coli (E. coli), including food borne pathogens such as Shiga toxin-producing E. coli, implies a problem for public health (van den Bogaard and Stobberingh, 2000). Horizontal gene transfer is an important route of the dissemination. Integrons are genetic elements able to capture gene cassettes encoding antibiotic resistance from the environment and incorporate them by site-specific recombination. Integrons are gene-capture and expression systems characterized by the presence of an intI gene encoding an integrase, a recombination site (attI), and a promoter. The most frequently reported mobile integrons are class 1 and class 2 integrons, which have been shown to contribute to the spread of antimicrobial resistance genes. It is important to remark that the presence of integrase is potentially indicative of strains capable of recruiting antibiotic resistance genes (Cambray et al., 2010). Moreover, resistance genes and resistant bacteria in the environment are considered an ecological problem. Therefore, the investigation of commensal bacteria is important in order to assess the extent of the drug resistance problem. The aim of the present study was to evaluate the susceptibility to antibiotics in commensal integron-positive E. coli isolated from pigs from a pig farm in Argentina.
Materia
Ciencias Veterinarias
antibioticos
Escherichia coli
cerdos
Integrones
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc/4.0/
Repositorio
CIC Digital (CICBA)
Institución
Comisión de Investigaciones Científicas de la Provincia de Buenos Aires
OAI Identificador
oai:digital.cic.gba.gob.ar:11746/5745

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network_acronym_str CICBA
repository_id_str 9441
network_name_str CIC Digital (CICBA)
spelling Multidrug resistance in Escherichia coli carrying integrons isolated from a pig farm with moderate antibiotic useTorre, Eulalia de laColello, RocíoFernández, DanielEtcheverría, Analía InésDi Conza, JoséGutkind, Gabriel O.Tapia, María OfeliaDieguez, Susana NellySoraci, Alejandro LuisPadola, Nora LíaCiencias VeterinariasantibioticosEscherichia colicerdosIntegronesThe emergence and dissemination of antimicrobial resistance in bacteria derived from food-producing animals is a consequence of intensive agricultural and veterinary use of antimicrobial compounds. The inappropriate use and prescribing of antibiotics, along with their use as growth promoters, is the main cause of the development of resistance. The potential risk of the transfer of this resistance through the food chain by bacteria such as Escherichia coli (E. coli), including food borne pathogens such as Shiga toxin-producing E. coli, implies a problem for public health (van den Bogaard and Stobberingh, 2000). Horizontal gene transfer is an important route of the dissemination. Integrons are genetic elements able to capture gene cassettes encoding antibiotic resistance from the environment and incorporate them by site-specific recombination. Integrons are gene-capture and expression systems characterized by the presence of an intI gene encoding an integrase, a recombination site (attI), and a promoter. The most frequently reported mobile integrons are class 1 and class 2 integrons, which have been shown to contribute to the spread of antimicrobial resistance genes. It is important to remark that the presence of integrase is potentially indicative of strains capable of recruiting antibiotic resistance genes (Cambray et al., 2010). Moreover, resistance genes and resistant bacteria in the environment are considered an ecological problem. Therefore, the investigation of commensal bacteria is important in order to assess the extent of the drug resistance problem. The aim of the present study was to evaluate the susceptibility to antibiotics in commensal integron-positive E. coli isolated from pigs from a pig farm in Argentina.Japan Science and Technology Information Aggregator, Electronic (J-STAGE)2015info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttps://digital.cic.gba.gob.ar/handle/11746/5745enginfo:eu-repo/semantics/altIdentifier/doi/10.2323/jgam.61.270Argentinainfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc/4.0/reponame:CIC Digital (CICBA)instname:Comisión de Investigaciones Científicas de la Provincia de Buenos Airesinstacron:CICBA2025-09-29T13:40:02Zoai:digital.cic.gba.gob.ar:11746/5745Institucionalhttp://digital.cic.gba.gob.arOrganismo científico-tecnológicoNo correspondehttp://digital.cic.gba.gob.ar/oai/snrdmarisa.degiusti@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:94412025-09-29 13:40:02.664CIC Digital (CICBA) - Comisión de Investigaciones Científicas de la Provincia de Buenos Airesfalse
dc.title.none.fl_str_mv Multidrug resistance in Escherichia coli carrying integrons isolated from a pig farm with moderate antibiotic use
title Multidrug resistance in Escherichia coli carrying integrons isolated from a pig farm with moderate antibiotic use
spellingShingle Multidrug resistance in Escherichia coli carrying integrons isolated from a pig farm with moderate antibiotic use
Torre, Eulalia de la
Ciencias Veterinarias
antibioticos
Escherichia coli
cerdos
Integrones
title_short Multidrug resistance in Escherichia coli carrying integrons isolated from a pig farm with moderate antibiotic use
title_full Multidrug resistance in Escherichia coli carrying integrons isolated from a pig farm with moderate antibiotic use
title_fullStr Multidrug resistance in Escherichia coli carrying integrons isolated from a pig farm with moderate antibiotic use
title_full_unstemmed Multidrug resistance in Escherichia coli carrying integrons isolated from a pig farm with moderate antibiotic use
title_sort Multidrug resistance in Escherichia coli carrying integrons isolated from a pig farm with moderate antibiotic use
dc.creator.none.fl_str_mv Torre, Eulalia de la
Colello, Rocío
Fernández, Daniel
Etcheverría, Analía Inés
Di Conza, José
Gutkind, Gabriel O.
Tapia, María Ofelia
Dieguez, Susana Nelly
Soraci, Alejandro Luis
Padola, Nora Lía
author Torre, Eulalia de la
author_facet Torre, Eulalia de la
Colello, Rocío
Fernández, Daniel
Etcheverría, Analía Inés
Di Conza, José
Gutkind, Gabriel O.
Tapia, María Ofelia
Dieguez, Susana Nelly
Soraci, Alejandro Luis
Padola, Nora Lía
author_role author
author2 Colello, Rocío
Fernández, Daniel
Etcheverría, Analía Inés
Di Conza, José
Gutkind, Gabriel O.
Tapia, María Ofelia
Dieguez, Susana Nelly
Soraci, Alejandro Luis
Padola, Nora Lía
author2_role author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Ciencias Veterinarias
antibioticos
Escherichia coli
cerdos
Integrones
topic Ciencias Veterinarias
antibioticos
Escherichia coli
cerdos
Integrones
dc.description.none.fl_txt_mv The emergence and dissemination of antimicrobial resistance in bacteria derived from food-producing animals is a consequence of intensive agricultural and veterinary use of antimicrobial compounds. The inappropriate use and prescribing of antibiotics, along with their use as growth promoters, is the main cause of the development of resistance. The potential risk of the transfer of this resistance through the food chain by bacteria such as Escherichia coli (E. coli), including food borne pathogens such as Shiga toxin-producing E. coli, implies a problem for public health (van den Bogaard and Stobberingh, 2000). Horizontal gene transfer is an important route of the dissemination. Integrons are genetic elements able to capture gene cassettes encoding antibiotic resistance from the environment and incorporate them by site-specific recombination. Integrons are gene-capture and expression systems characterized by the presence of an intI gene encoding an integrase, a recombination site (attI), and a promoter. The most frequently reported mobile integrons are class 1 and class 2 integrons, which have been shown to contribute to the spread of antimicrobial resistance genes. It is important to remark that the presence of integrase is potentially indicative of strains capable of recruiting antibiotic resistance genes (Cambray et al., 2010). Moreover, resistance genes and resistant bacteria in the environment are considered an ecological problem. Therefore, the investigation of commensal bacteria is important in order to assess the extent of the drug resistance problem. The aim of the present study was to evaluate the susceptibility to antibiotics in commensal integron-positive E. coli isolated from pigs from a pig farm in Argentina.
description The emergence and dissemination of antimicrobial resistance in bacteria derived from food-producing animals is a consequence of intensive agricultural and veterinary use of antimicrobial compounds. The inappropriate use and prescribing of antibiotics, along with their use as growth promoters, is the main cause of the development of resistance. The potential risk of the transfer of this resistance through the food chain by bacteria such as Escherichia coli (E. coli), including food borne pathogens such as Shiga toxin-producing E. coli, implies a problem for public health (van den Bogaard and Stobberingh, 2000). Horizontal gene transfer is an important route of the dissemination. Integrons are genetic elements able to capture gene cassettes encoding antibiotic resistance from the environment and incorporate them by site-specific recombination. Integrons are gene-capture and expression systems characterized by the presence of an intI gene encoding an integrase, a recombination site (attI), and a promoter. The most frequently reported mobile integrons are class 1 and class 2 integrons, which have been shown to contribute to the spread of antimicrobial resistance genes. It is important to remark that the presence of integrase is potentially indicative of strains capable of recruiting antibiotic resistance genes (Cambray et al., 2010). Moreover, resistance genes and resistant bacteria in the environment are considered an ecological problem. Therefore, the investigation of commensal bacteria is important in order to assess the extent of the drug resistance problem. The aim of the present study was to evaluate the susceptibility to antibiotics in commensal integron-positive E. coli isolated from pigs from a pig farm in Argentina.
publishDate 2015
dc.date.none.fl_str_mv 2015
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://digital.cic.gba.gob.ar/handle/11746/5745
url https://digital.cic.gba.gob.ar/handle/11746/5745
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.2323/jgam.61.270
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc/4.0/
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc/4.0/
dc.format.none.fl_str_mv application/pdf
dc.coverage.none.fl_str_mv Argentina
dc.publisher.none.fl_str_mv Japan Science and Technology Information Aggregator, Electronic (J-STAGE)
publisher.none.fl_str_mv Japan Science and Technology Information Aggregator, Electronic (J-STAGE)
dc.source.none.fl_str_mv reponame:CIC Digital (CICBA)
instname:Comisión de Investigaciones Científicas de la Provincia de Buenos Aires
instacron:CICBA
reponame_str CIC Digital (CICBA)
collection CIC Digital (CICBA)
instname_str Comisión de Investigaciones Científicas de la Provincia de Buenos Aires
instacron_str CICBA
institution CICBA
repository.name.fl_str_mv CIC Digital (CICBA) - Comisión de Investigaciones Científicas de la Provincia de Buenos Aires
repository.mail.fl_str_mv marisa.degiusti@sedici.unlp.edu.ar
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