Partial molecular characterization of different proviral strains of bovine leukemia virus
- Autores
- Juliarena, Marcela A.; Lendez, Pamela A.; Gutierrez, Silvina E.; Forletti, Agustina; Rensetti, Daniel Ernesto; Ceriani, Maria Carolina
- Año de publicación
- 2012
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión enviada
- Descripción
- Bovine leukemia virus (BLV)-infected cattle were classified by their proviral load into low and high proviral load profiles (LPL and HPL, respectively). Blood from these animals was used to infect sheep to obtain multiple identical copies of integrated provirus. An env fragment of BLV was amplified from all infected sheep and sequenced. The sequences that were obtained were compared to already published BLV genome sequence, resulting in three clusters. Mutations could not be attributed to the passage of provirus from cattle to sheep and subsequent amplification and sequencing. The description of two different proviral load profiles, the association of the BoLA-DRB3.2 0902 allele with the LPL profile, the availability of complete BLV sequences, and the comparison of a variable region of the env gene from carefully characterized cattle are still not enough to explain the presence of animals in every herd that are resistant to BLV dissemination.
- Materia
-
Ciencias Veterinarias
Bovine leukemia virus (BLV)
BoLA-DRB3.2*0902 allele
env gene - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- http://creativecommons.org/licenses/by/4.0/
- Repositorio
- Institución
- Comisión de Investigaciones Científicas de la Provincia de Buenos Aires
- OAI Identificador
- oai:digital.cic.gba.gob.ar:11746/5331
Ver los metadatos del registro completo
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oai:digital.cic.gba.gob.ar:11746/5331 |
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network_name_str |
CIC Digital (CICBA) |
spelling |
Partial molecular characterization of different proviral strains of bovine leukemia virusJuliarena, Marcela A.Lendez, Pamela A.Gutierrez, Silvina E.Forletti, AgustinaRensetti, Daniel ErnestoCeriani, Maria CarolinaCiencias VeterinariasBovine leukemia virus (BLV)BoLA-DRB3.2*0902 alleleenv geneBovine leukemia virus (BLV)-infected cattle were classified by their proviral load into low and high proviral load profiles (LPL and HPL, respectively). Blood from these animals was used to infect sheep to obtain multiple identical copies of integrated provirus. An env fragment of BLV was amplified from all infected sheep and sequenced. The sequences that were obtained were compared to already published BLV genome sequence, resulting in three clusters. Mutations could not be attributed to the passage of provirus from cattle to sheep and subsequent amplification and sequencing. The description of two different proviral load profiles, the association of the BoLA-DRB3.2 0902 allele with the LPL profile, the availability of complete BLV sequences, and the comparison of a variable region of the env gene from carefully characterized cattle are still not enough to explain the presence of animals in every herd that are resistant to BLV dissemination.2012info:eu-repo/semantics/articleinfo:eu-repo/semantics/submittedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttps://digital.cic.gba.gob.ar/handle/11746/5331enginfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/4.0/reponame:CIC Digital (CICBA)instname:Comisión de Investigaciones Científicas de la Provincia de Buenos Airesinstacron:CICBA2025-09-29T13:40:18Zoai:digital.cic.gba.gob.ar:11746/5331Institucionalhttp://digital.cic.gba.gob.arOrganismo científico-tecnológicoNo correspondehttp://digital.cic.gba.gob.ar/oai/snrdmarisa.degiusti@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:94412025-09-29 13:40:18.98CIC Digital (CICBA) - Comisión de Investigaciones Científicas de la Provincia de Buenos Airesfalse |
dc.title.none.fl_str_mv |
Partial molecular characterization of different proviral strains of bovine leukemia virus |
title |
Partial molecular characterization of different proviral strains of bovine leukemia virus |
spellingShingle |
Partial molecular characterization of different proviral strains of bovine leukemia virus Juliarena, Marcela A. Ciencias Veterinarias Bovine leukemia virus (BLV) BoLA-DRB3.2*0902 allele env gene |
title_short |
Partial molecular characterization of different proviral strains of bovine leukemia virus |
title_full |
Partial molecular characterization of different proviral strains of bovine leukemia virus |
title_fullStr |
Partial molecular characterization of different proviral strains of bovine leukemia virus |
title_full_unstemmed |
Partial molecular characterization of different proviral strains of bovine leukemia virus |
title_sort |
Partial molecular characterization of different proviral strains of bovine leukemia virus |
dc.creator.none.fl_str_mv |
Juliarena, Marcela A. Lendez, Pamela A. Gutierrez, Silvina E. Forletti, Agustina Rensetti, Daniel Ernesto Ceriani, Maria Carolina |
author |
Juliarena, Marcela A. |
author_facet |
Juliarena, Marcela A. Lendez, Pamela A. Gutierrez, Silvina E. Forletti, Agustina Rensetti, Daniel Ernesto Ceriani, Maria Carolina |
author_role |
author |
author2 |
Lendez, Pamela A. Gutierrez, Silvina E. Forletti, Agustina Rensetti, Daniel Ernesto Ceriani, Maria Carolina |
author2_role |
author author author author author |
dc.subject.none.fl_str_mv |
Ciencias Veterinarias Bovine leukemia virus (BLV) BoLA-DRB3.2*0902 allele env gene |
topic |
Ciencias Veterinarias Bovine leukemia virus (BLV) BoLA-DRB3.2*0902 allele env gene |
dc.description.none.fl_txt_mv |
Bovine leukemia virus (BLV)-infected cattle were classified by their proviral load into low and high proviral load profiles (LPL and HPL, respectively). Blood from these animals was used to infect sheep to obtain multiple identical copies of integrated provirus. An env fragment of BLV was amplified from all infected sheep and sequenced. The sequences that were obtained were compared to already published BLV genome sequence, resulting in three clusters. Mutations could not be attributed to the passage of provirus from cattle to sheep and subsequent amplification and sequencing. The description of two different proviral load profiles, the association of the BoLA-DRB3.2 0902 allele with the LPL profile, the availability of complete BLV sequences, and the comparison of a variable region of the env gene from carefully characterized cattle are still not enough to explain the presence of animals in every herd that are resistant to BLV dissemination. |
description |
Bovine leukemia virus (BLV)-infected cattle were classified by their proviral load into low and high proviral load profiles (LPL and HPL, respectively). Blood from these animals was used to infect sheep to obtain multiple identical copies of integrated provirus. An env fragment of BLV was amplified from all infected sheep and sequenced. The sequences that were obtained were compared to already published BLV genome sequence, resulting in three clusters. Mutations could not be attributed to the passage of provirus from cattle to sheep and subsequent amplification and sequencing. The description of two different proviral load profiles, the association of the BoLA-DRB3.2 0902 allele with the LPL profile, the availability of complete BLV sequences, and the comparison of a variable region of the env gene from carefully characterized cattle are still not enough to explain the presence of animals in every herd that are resistant to BLV dissemination. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/submittedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
submittedVersion |
dc.identifier.none.fl_str_mv |
https://digital.cic.gba.gob.ar/handle/11746/5331 |
url |
https://digital.cic.gba.gob.ar/handle/11746/5331 |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/4.0/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
http://creativecommons.org/licenses/by/4.0/ |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:CIC Digital (CICBA) instname:Comisión de Investigaciones Científicas de la Provincia de Buenos Aires instacron:CICBA |
reponame_str |
CIC Digital (CICBA) |
collection |
CIC Digital (CICBA) |
instname_str |
Comisión de Investigaciones Científicas de la Provincia de Buenos Aires |
instacron_str |
CICBA |
institution |
CICBA |
repository.name.fl_str_mv |
CIC Digital (CICBA) - Comisión de Investigaciones Científicas de la Provincia de Buenos Aires |
repository.mail.fl_str_mv |
marisa.degiusti@sedici.unlp.edu.ar |
_version_ |
1844618615752491008 |
score |
13.070432 |