First total synthesis of (+)-Neplanocin B

Autores
Comin, M.J.; Pellegrinet, S.C.; Rodriguez, J.B.
Año de publicación
2005
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
(+)-Neplanocin B ((+)-5), the unnatural isomer of a minor component of the neplanocin family of antibiotics was enantioselectively synthesized starting from D-ribono-1,4-lactone. This synthetic strategy employed (+)-9-[(1R, 2R, 5S)-5-Benzyloxy-3-(benzyloxy)methyl-2-hydroxycyclopent-3-en-1-yl] -6-chloropurine (compound 7) as an advanced synthetic intermediate. ©ARKAT.
Fil:Comin, M.J. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina.
Fil:Rodriguez, J.B. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina.
Fuente
Arkivoc 2005;2005(12):205-213
Materia
6-oxabicyclo[3.1.0]hexane
Ampullariella regularis
Carbocyclic nucleosides
Conformationally locked nucleosides
Neplanocin B
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by/2.5/ar
Repositorio
Biblioteca Digital (UBA-FCEN)
Institución
Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales
OAI Identificador
paperaa:paper_14246376_v2005_n12_p205_Comin
Acceder
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oai_identifier_str paperaa:paper_14246376_v2005_n12_p205_Comin
network_acronym_str BDUBAFCEN
repository_id_str 1896
network_name_str Biblioteca Digital (UBA-FCEN)
spelling First total synthesis of (+)-Neplanocin BComin, M.J.Pellegrinet, S.C.Rodriguez, J.B.6-oxabicyclo[3.1.0]hexaneAmpullariella regularisCarbocyclic nucleosidesConformationally locked nucleosidesNeplanocin B(+)-Neplanocin B ((+)-5), the unnatural isomer of a minor component of the neplanocin family of antibiotics was enantioselectively synthesized starting from D-ribono-1,4-lactone. This synthetic strategy employed (+)-9-[(1R, 2R, 5S)-5-Benzyloxy-3-(benzyloxy)methyl-2-hydroxycyclopent-3-en-1-yl] -6-chloropurine (compound 7) as an advanced synthetic intermediate. ©ARKAT.Fil:Comin, M.J. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina.Fil:Rodriguez, J.B. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina.2005info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://hdl.handle.net/20.500.12110/paper_14246376_v2005_n12_p205_CominArkivoc 2005;2005(12):205-213reponame:Biblioteca Digital (UBA-FCEN)instname:Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturalesinstacron:UBA-FCENenginfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/2.5/ar2025-09-04T09:48:27Zpaperaa:paper_14246376_v2005_n12_p205_CominInstitucionalhttps://digital.bl.fcen.uba.ar/Universidad públicaNo correspondehttps://digital.bl.fcen.uba.ar/cgi-bin/oaiserver.cgiana@bl.fcen.uba.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:18962025-09-04 09:48:31.445Biblioteca Digital (UBA-FCEN) - Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturalesfalse
dc.title.none.fl_str_mv First total synthesis of (+)-Neplanocin B
title First total synthesis of (+)-Neplanocin B
spellingShingle First total synthesis of (+)-Neplanocin B
Comin, M.J.
6-oxabicyclo[3.1.0]hexane
Ampullariella regularis
Carbocyclic nucleosides
Conformationally locked nucleosides
Neplanocin B
title_short First total synthesis of (+)-Neplanocin B
title_full First total synthesis of (+)-Neplanocin B
title_fullStr First total synthesis of (+)-Neplanocin B
title_full_unstemmed First total synthesis of (+)-Neplanocin B
title_sort First total synthesis of (+)-Neplanocin B
dc.creator.none.fl_str_mv Comin, M.J.
Pellegrinet, S.C.
Rodriguez, J.B.
author Comin, M.J.
author_facet Comin, M.J.
Pellegrinet, S.C.
Rodriguez, J.B.
author_role author
author2 Pellegrinet, S.C.
Rodriguez, J.B.
author2_role author
author
dc.subject.none.fl_str_mv 6-oxabicyclo[3.1.0]hexane
Ampullariella regularis
Carbocyclic nucleosides
Conformationally locked nucleosides
Neplanocin B
topic 6-oxabicyclo[3.1.0]hexane
Ampullariella regularis
Carbocyclic nucleosides
Conformationally locked nucleosides
Neplanocin B
dc.description.none.fl_txt_mv (+)-Neplanocin B ((+)-5), the unnatural isomer of a minor component of the neplanocin family of antibiotics was enantioselectively synthesized starting from D-ribono-1,4-lactone. This synthetic strategy employed (+)-9-[(1R, 2R, 5S)-5-Benzyloxy-3-(benzyloxy)methyl-2-hydroxycyclopent-3-en-1-yl] -6-chloropurine (compound 7) as an advanced synthetic intermediate. ©ARKAT.
Fil:Comin, M.J. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina.
Fil:Rodriguez, J.B. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina.
description (+)-Neplanocin B ((+)-5), the unnatural isomer of a minor component of the neplanocin family of antibiotics was enantioselectively synthesized starting from D-ribono-1,4-lactone. This synthetic strategy employed (+)-9-[(1R, 2R, 5S)-5-Benzyloxy-3-(benzyloxy)methyl-2-hydroxycyclopent-3-en-1-yl] -6-chloropurine (compound 7) as an advanced synthetic intermediate. ©ARKAT.
publishDate 2005
dc.date.none.fl_str_mv 2005
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12110/paper_14246376_v2005_n12_p205_Comin
url http://hdl.handle.net/20.500.12110/paper_14246376_v2005_n12_p205_Comin
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/2.5/ar
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/2.5/ar
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv Arkivoc 2005;2005(12):205-213
reponame:Biblioteca Digital (UBA-FCEN)
instname:Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales
instacron:UBA-FCEN
reponame_str Biblioteca Digital (UBA-FCEN)
collection Biblioteca Digital (UBA-FCEN)
instname_str Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales
instacron_str UBA-FCEN
institution UBA-FCEN
repository.name.fl_str_mv Biblioteca Digital (UBA-FCEN) - Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales
repository.mail.fl_str_mv ana@bl.fcen.uba.ar
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score 12.623145

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