Tracheal remodelling in response to hypoxia

Autores
Centanin, L.; Gorr, T.A.; Wappner, P.
Año de publicación
2010
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The insect tracheal system is a continuous tubular network that ramifies into progressively thinner branches to provide air directly to every organ and tissue throughout the body. During embryogenesis the basic architecture of the tracheal system develops in a stereotypical and genetically controlled manner. Later, in larval stages, the tracheal system becomes plastic, and adapts to particular oxygen needs of the different tissues of the body. Oxygen sensing is mediated by specific prolyl-4-hydroxylases that regulate protein stability of the alpha subunit of oxygen-responsive transcription factors from the HIF family. Tracheal cells are exquisitely sensitive to oxygen levels, modulating the expression of hypoxia-inducible proteins that mediate sprouting of tracheal branches in direction to oxygen-deprived tissues. © 2009 Elsevier Ltd. All rights reserved.
Fil:Centanin, L. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina.
Fil:Wappner, P. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina.
Fuente
J. Insect Physiol. 2010;56(5):447-454
Materia
Cell autonomy
HIF
Hypoxia
Plasticity
Tracheae
embryonic development
enzyme
hypoxia
insect
larval development
adaptation
animal
animal anatomy
anoxia
growth, development and aging
histology
insect
larva
physiology
review
Adaptation, Physiological
Animal Structures
Animals
Anoxia
Insects
Larva
Hexapoda
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by/2.5/ar
Repositorio
Biblioteca Digital (UBA-FCEN)
Institución
Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales
OAI Identificador
paperaa:paper_00221910_v56_n5_p447_Centanin
Acceder
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oai_identifier_str paperaa:paper_00221910_v56_n5_p447_Centanin
network_acronym_str BDUBAFCEN
repository_id_str 1896
network_name_str Biblioteca Digital (UBA-FCEN)
spelling Tracheal remodelling in response to hypoxiaCentanin, L.Gorr, T.A.Wappner, P.Cell autonomyHIFHypoxiaPlasticityTracheaeembryonic developmentenzymehypoxiainsectlarval developmentadaptationanimalanimal anatomyanoxiagrowth, development and aginghistologyinsectlarvaphysiologyreviewAdaptation, PhysiologicalAnimal StructuresAnimalsAnoxiaInsectsLarvaHexapodaThe insect tracheal system is a continuous tubular network that ramifies into progressively thinner branches to provide air directly to every organ and tissue throughout the body. During embryogenesis the basic architecture of the tracheal system develops in a stereotypical and genetically controlled manner. Later, in larval stages, the tracheal system becomes plastic, and adapts to particular oxygen needs of the different tissues of the body. Oxygen sensing is mediated by specific prolyl-4-hydroxylases that regulate protein stability of the alpha subunit of oxygen-responsive transcription factors from the HIF family. Tracheal cells are exquisitely sensitive to oxygen levels, modulating the expression of hypoxia-inducible proteins that mediate sprouting of tracheal branches in direction to oxygen-deprived tissues. © 2009 Elsevier Ltd. All rights reserved.Fil:Centanin, L. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina.Fil:Wappner, P. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina.2010info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://hdl.handle.net/20.500.12110/paper_00221910_v56_n5_p447_CentaninJ. Insect Physiol. 2010;56(5):447-454reponame:Biblioteca Digital (UBA-FCEN)instname:Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturalesinstacron:UBA-FCENenginfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/2.5/ar2026-02-05T12:42:37Zpaperaa:paper_00221910_v56_n5_p447_CentaninInstitucionalhttps://digital.bl.fcen.uba.ar/Universidad públicaNo correspondehttps://digital.bl.fcen.uba.ar/cgi-bin/oaiserver.cgiana@bl.fcen.uba.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:18962026-02-05 12:42:38.512Biblioteca Digital (UBA-FCEN) - Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturalesfalse
dc.title.none.fl_str_mv Tracheal remodelling in response to hypoxia
title Tracheal remodelling in response to hypoxia
spellingShingle Tracheal remodelling in response to hypoxia
Centanin, L.
Cell autonomy
HIF
Hypoxia
Plasticity
Tracheae
embryonic development
enzyme
hypoxia
insect
larval development
adaptation
animal
animal anatomy
anoxia
growth, development and aging
histology
insect
larva
physiology
review
Adaptation, Physiological
Animal Structures
Animals
Anoxia
Insects
Larva
Hexapoda
title_short Tracheal remodelling in response to hypoxia
title_full Tracheal remodelling in response to hypoxia
title_fullStr Tracheal remodelling in response to hypoxia
title_full_unstemmed Tracheal remodelling in response to hypoxia
title_sort Tracheal remodelling in response to hypoxia
dc.creator.none.fl_str_mv Centanin, L.
Gorr, T.A.
Wappner, P.
author Centanin, L.
author_facet Centanin, L.
Gorr, T.A.
Wappner, P.
author_role author
author2 Gorr, T.A.
Wappner, P.
author2_role author
author
dc.subject.none.fl_str_mv Cell autonomy
HIF
Hypoxia
Plasticity
Tracheae
embryonic development
enzyme
hypoxia
insect
larval development
adaptation
animal
animal anatomy
anoxia
growth, development and aging
histology
insect
larva
physiology
review
Adaptation, Physiological
Animal Structures
Animals
Anoxia
Insects
Larva
Hexapoda
topic Cell autonomy
HIF
Hypoxia
Plasticity
Tracheae
embryonic development
enzyme
hypoxia
insect
larval development
adaptation
animal
animal anatomy
anoxia
growth, development and aging
histology
insect
larva
physiology
review
Adaptation, Physiological
Animal Structures
Animals
Anoxia
Insects
Larva
Hexapoda
dc.description.none.fl_txt_mv The insect tracheal system is a continuous tubular network that ramifies into progressively thinner branches to provide air directly to every organ and tissue throughout the body. During embryogenesis the basic architecture of the tracheal system develops in a stereotypical and genetically controlled manner. Later, in larval stages, the tracheal system becomes plastic, and adapts to particular oxygen needs of the different tissues of the body. Oxygen sensing is mediated by specific prolyl-4-hydroxylases that regulate protein stability of the alpha subunit of oxygen-responsive transcription factors from the HIF family. Tracheal cells are exquisitely sensitive to oxygen levels, modulating the expression of hypoxia-inducible proteins that mediate sprouting of tracheal branches in direction to oxygen-deprived tissues. © 2009 Elsevier Ltd. All rights reserved.
Fil:Centanin, L. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina.
Fil:Wappner, P. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina.
description The insect tracheal system is a continuous tubular network that ramifies into progressively thinner branches to provide air directly to every organ and tissue throughout the body. During embryogenesis the basic architecture of the tracheal system develops in a stereotypical and genetically controlled manner. Later, in larval stages, the tracheal system becomes plastic, and adapts to particular oxygen needs of the different tissues of the body. Oxygen sensing is mediated by specific prolyl-4-hydroxylases that regulate protein stability of the alpha subunit of oxygen-responsive transcription factors from the HIF family. Tracheal cells are exquisitely sensitive to oxygen levels, modulating the expression of hypoxia-inducible proteins that mediate sprouting of tracheal branches in direction to oxygen-deprived tissues. © 2009 Elsevier Ltd. All rights reserved.
publishDate 2010
dc.date.none.fl_str_mv 2010
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12110/paper_00221910_v56_n5_p447_Centanin
url http://hdl.handle.net/20.500.12110/paper_00221910_v56_n5_p447_Centanin
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/2.5/ar
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/2.5/ar
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv J. Insect Physiol. 2010;56(5):447-454
reponame:Biblioteca Digital (UBA-FCEN)
instname:Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales
instacron:UBA-FCEN
reponame_str Biblioteca Digital (UBA-FCEN)
collection Biblioteca Digital (UBA-FCEN)
instname_str Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales
instacron_str UBA-FCEN
institution UBA-FCEN
repository.name.fl_str_mv Biblioteca Digital (UBA-FCEN) - Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales
repository.mail.fl_str_mv ana@bl.fcen.uba.ar
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score 13.115731

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