Antiviral treatment of Argentine hemorrhagic fever

Autores
Enria, Delia; Maiztegui, Julio I.
Año de publicación
1994
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Fil: Enria, Delia. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Virales Humanas; Argentina.
Fil: Maiztegui, Julio I. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Virales Humanas; Argentina.
Argentine hemorrhagic fever is a systemic viral disease caused by Junin virus, with a mortality of 15-30% in untreated individuals. Current specific therapy is highly effective in reducing mortality, and consists of the early administration of immune plasma in defined doses of specific neutralizing antibodies per kg of body weight. However, several reasons suggest the need to investigate alternative therapies. Ribavirin, a broad spectrum antiviral agent, is effective in the treatment of other viral hemorrhagic fevers, and the studies done with Junin virus infections to date indicate that this drug may also have a beneficial effect in Argentine hemorrhagic fever.
Fuente
Antiviral Research 1994; 23(1):23-31.
Materia
Fiebre Hemorrágica Americana
Argentina
Antivirales
Nivel de accesibilidad
acceso abierto
Condiciones de uso
Repositorio
Sistema de Gestión del Conocimiento ANLIS MALBRÁN
Institución
Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"
OAI Identificador
oai:sgc.anlis.gob.ar:123456789/1952
Acceder
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network_acronym_str SGCANLIS
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spelling Antiviral treatment of Argentine hemorrhagic feverEnria, DeliaMaiztegui, Julio I.Fiebre Hemorrágica AmericanaArgentinaAntiviralesFil: Enria, Delia. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Virales Humanas; Argentina.Fil: Maiztegui, Julio I. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Virales Humanas; Argentina.Argentine hemorrhagic fever is a systemic viral disease caused by Junin virus, with a mortality of 15-30% in untreated individuals. Current specific therapy is highly effective in reducing mortality, and consists of the early administration of immune plasma in defined doses of specific neutralizing antibodies per kg of body weight. However, several reasons suggest the need to investigate alternative therapies. Ribavirin, a broad spectrum antiviral agent, is effective in the treatment of other viral hemorrhagic fevers, and the studies done with Junin virus infections to date indicate that this drug may also have a beneficial effect in Argentine hemorrhagic fever.Elsevier1994-01info:ar-repo/semantics/articuloinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdf0166-3542http://sgc.anlis.gob.ar/handle/123456789/195210.1016/0166-3542(94)90030-2Antiviral Research 1994; 23(1):23-31.reponame:Sistema de Gestión del Conocimiento ANLIS MALBRÁNinstname:Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"instacron:ANLISAntiviral researchenginfo:eu-repo/semantics/openAccess2025-09-29T14:30:33Zoai:sgc.anlis.gob.ar:123456789/1952Institucionalhttp://sgc.anlis.gob.ar/Organismo científico-tecnológicoNo correspondehttp://sgc.anlis.gob.ar/oai/biblioteca@anlis.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:a2025-09-29 14:30:33.55Sistema de Gestión del Conocimiento ANLIS MALBRÁN - Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"false
dc.title.none.fl_str_mv Antiviral treatment of Argentine hemorrhagic fever
title Antiviral treatment of Argentine hemorrhagic fever
spellingShingle Antiviral treatment of Argentine hemorrhagic fever
Enria, Delia
Fiebre Hemorrágica Americana
Argentina
Antivirales
title_short Antiviral treatment of Argentine hemorrhagic fever
title_full Antiviral treatment of Argentine hemorrhagic fever
title_fullStr Antiviral treatment of Argentine hemorrhagic fever
title_full_unstemmed Antiviral treatment of Argentine hemorrhagic fever
title_sort Antiviral treatment of Argentine hemorrhagic fever
dc.creator.none.fl_str_mv Enria, Delia
Maiztegui, Julio I.
author Enria, Delia
author_facet Enria, Delia
Maiztegui, Julio I.
author_role author
author2 Maiztegui, Julio I.
author2_role author
dc.subject.none.fl_str_mv Fiebre Hemorrágica Americana
Argentina
Antivirales
topic Fiebre Hemorrágica Americana
Argentina
Antivirales
dc.description.none.fl_txt_mv Fil: Enria, Delia. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Virales Humanas; Argentina.
Fil: Maiztegui, Julio I. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Virales Humanas; Argentina.
Argentine hemorrhagic fever is a systemic viral disease caused by Junin virus, with a mortality of 15-30% in untreated individuals. Current specific therapy is highly effective in reducing mortality, and consists of the early administration of immune plasma in defined doses of specific neutralizing antibodies per kg of body weight. However, several reasons suggest the need to investigate alternative therapies. Ribavirin, a broad spectrum antiviral agent, is effective in the treatment of other viral hemorrhagic fevers, and the studies done with Junin virus infections to date indicate that this drug may also have a beneficial effect in Argentine hemorrhagic fever.
description Fil: Enria, Delia. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Virales Humanas; Argentina.
publishDate 1994
dc.date.none.fl_str_mv 1994-01
dc.type.none.fl_str_mv info:ar-repo/semantics/articulo
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv 0166-3542
http://sgc.anlis.gob.ar/handle/123456789/1952
10.1016/0166-3542(94)90030-2
identifier_str_mv 0166-3542
10.1016/0166-3542(94)90030-2
url http://sgc.anlis.gob.ar/handle/123456789/1952
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Antiviral research
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv Antiviral Research 1994; 23(1):23-31.
reponame:Sistema de Gestión del Conocimiento ANLIS MALBRÁN
instname:Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"
instacron:ANLIS
reponame_str Sistema de Gestión del Conocimiento ANLIS MALBRÁN
collection Sistema de Gestión del Conocimiento ANLIS MALBRÁN
instname_str Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"
instacron_str ANLIS
institution ANLIS
repository.name.fl_str_mv Sistema de Gestión del Conocimiento ANLIS MALBRÁN - Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"
repository.mail.fl_str_mv biblioteca@anlis.gov.ar
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