Molecular identification and characterization of two proposed new enterovirus serotypes, EV74 and EV75

Autores
Oberste, M. Steven; Michele, Suzanne M.; Maher, Kaija; Schnurr, David; Cisterna, Daniel; Junttila, Nina; Uddin, Moyez; Chomel, Jean-Jacques; Lau, Chi-Shan; Ridha, Walid; Al-Busaidy, Suleiman; Norder, Helene; Magnius, Lars O.; Pallansch, Mark A.
Año de publicación
2004
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Fil: Oberste, M. Steven. Centers for Disease Control and Prevention. Respiratory and Enteric Viruses Branch; Estados Unidos.
Fil: Michele, Suzanne M. Centers for Disease Control and Prevention. Respiratory and Enteric Viruses Branch; Estados Unidos.
Fil: Maher, Kaija. Centers for Disease Control and Prevention. Respiratory and Enteric Viruses Branch; Estados Unidos.
Fil: Schnurr, David. California Department of Health Services. Viral and Rickettsial Disease Laboratory; Estados Unidos.
Fil: Cisterna, Daniel. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina.
Fil: Junttila, Nina. Swedish Institute for Disease Control. Department of Virology; Suecia.
Fil: Uddin, Moyez. Institute of Public Health; Bangladesh.
Fil: Chomel, Jean-Jacques. Centre National de Référence des Entérovirus; Francia.
Fil: Lau, Chi-Shan. Queen Mary Hospital. Department of Health; China.
Fil: Ridha, Walid. National Polio Laboratory; Irak.
Fil: Al-Busaidy, Suleiman. Ministry of Health. Department of Laboratories; Oman.
Fil: Norder, Helene. Swedish Institute for Disease Control. Department of Virology; Suecia.
Fil: Magnius, Lars O. Swedish Institute for Disease Control. Department of Virology; Suecia.
Fil: Pallansch, Mark A. Centers for Disease Control and Prevention. Respiratory and Enteric Viruses Branch; Estados Unidos.
Sequencing of the gene that encodes the capsid protein VP1 has been used as a surrogate for antigenic typing in order to distinguish enterovirus serotypes; three new serotypes were identified recently by this method. In this study, 14 enterovirus isolates from six countries were characterized as members of two new types within the species Human enterovirus B, based on sequencing of the complete capsid-encoding (P1) region. Isolates within each of these two types differed significantly from one another and from all other known enterovirus serotypes on the basis of sequences that encode either VP1 alone or the entire P1 region. Members of each type were greater than or equal to 77(.)2% identical to one another (89(.)5% amino acid identity) in VP1, but members of the two different types differed from one another and from other enteroviruses by greater than or equal to 31% in nucleotide sequence (25% amino acid sequence difference), indicating that the two groups represent separate new candidate enterovirus types. The complete P1 sequences differed from those of all other enterovirus serotypes by greater than or equal to 31% (26% amino acid sequence difference), but were highly conserved within a serotype (< 8% amino acid sequence difference). Phylogenetic analyses demonstrated that isolates of the same serotype were monophyletic in both VP1 and the capsid as a whole, as shown previously for other enterovirus serotypes. This paper proposes that these 14 isolates should be classified as members of two new human enterovirus types, enteroviruses 74 and 75 (EV74 and EV75).
Fuente
Journal of General Virology 2004;85(11):3205-3212
Materia
Enterovirus
Enterovirus Humano B
Picornaviridae
Nivel de accesibilidad
acceso abierto
Condiciones de uso
Repositorio
Sistema de Gestión del Conocimiento ANLIS MALBRÁN
Institución
Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"
OAI Identificador
oai:sgc.anlis.gob.ar:Publications/123456789/396

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oai_identifier_str oai:sgc.anlis.gob.ar:Publications/123456789/396
network_acronym_str SGCANLIS
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network_name_str Sistema de Gestión del Conocimiento ANLIS MALBRÁN
spelling Molecular identification and characterization of two proposed new enterovirus serotypes, EV74 and EV75Oberste, M. StevenMichele, Suzanne M.Maher, KaijaSchnurr, DavidCisterna, DanielJunttila, NinaUddin, MoyezChomel, Jean-JacquesLau, Chi-ShanRidha, WalidAl-Busaidy, SuleimanNorder, HeleneMagnius, Lars O.Pallansch, Mark A.EnterovirusEnterovirus Humano BPicornaviridaeFil: Oberste, M. Steven. Centers for Disease Control and Prevention. Respiratory and Enteric Viruses Branch; Estados Unidos.Fil: Michele, Suzanne M. Centers for Disease Control and Prevention. Respiratory and Enteric Viruses Branch; Estados Unidos.Fil: Maher, Kaija. Centers for Disease Control and Prevention. Respiratory and Enteric Viruses Branch; Estados Unidos.Fil: Schnurr, David. California Department of Health Services. Viral and Rickettsial Disease Laboratory; Estados Unidos.Fil: Cisterna, Daniel. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina.Fil: Junttila, Nina. Swedish Institute for Disease Control. Department of Virology; Suecia.Fil: Uddin, Moyez. Institute of Public Health; Bangladesh.Fil: Chomel, Jean-Jacques. Centre National de Référence des Entérovirus; Francia.Fil: Lau, Chi-Shan. Queen Mary Hospital. Department of Health; China.Fil: Ridha, Walid. National Polio Laboratory; Irak.Fil: Al-Busaidy, Suleiman. Ministry of Health. Department of Laboratories; Oman.Fil: Norder, Helene. Swedish Institute for Disease Control. Department of Virology; Suecia.Fil: Magnius, Lars O. Swedish Institute for Disease Control. Department of Virology; Suecia.Fil: Pallansch, Mark A. Centers for Disease Control and Prevention. Respiratory and Enteric Viruses Branch; Estados Unidos.Sequencing of the gene that encodes the capsid protein VP1 has been used as a surrogate for antigenic typing in order to distinguish enterovirus serotypes; three new serotypes were identified recently by this method. In this study, 14 enterovirus isolates from six countries were characterized as members of two new types within the species Human enterovirus B, based on sequencing of the complete capsid-encoding (P1) region. Isolates within each of these two types differed significantly from one another and from all other known enterovirus serotypes on the basis of sequences that encode either VP1 alone or the entire P1 region. Members of each type were greater than or equal to 77(.)2% identical to one another (89(.)5% amino acid identity) in VP1, but members of the two different types differed from one another and from other enteroviruses by greater than or equal to 31% in nucleotide sequence (25% amino acid sequence difference), indicating that the two groups represent separate new candidate enterovirus types. The complete P1 sequences differed from those of all other enterovirus serotypes by greater than or equal to 31% (26% amino acid sequence difference), but were highly conserved within a serotype (< 8% amino acid sequence difference). Phylogenetic analyses demonstrated that isolates of the same serotype were monophyletic in both VP1 and the capsid as a whole, as shown previously for other enterovirus serotypes. This paper proposes that these 14 isolates should be classified as members of two new human enterovirus types, enteroviruses 74 and 75 (EV74 and EV75).2004info:ar-repo/semantics/articuloinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdf0022-1317http://sgc.anlis.gob.ar/handle/123456789/396http://vir.sgmjournals.org/content/85/11/3205.full.pdf10.1099/vir.0.80148-0Journal of General Virology 2004;85(11):3205-3212reponame:Sistema de Gestión del Conocimiento ANLIS MALBRÁNinstname:Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"instacron:ANLISThe Journal of general virologyenginfo:eu-repo/semantics/openAccess2025-09-04T11:15:47Zoai:sgc.anlis.gob.ar:Publications/123456789/396Institucionalhttp://sgc.anlis.gob.ar/Organismo científico-tecnológicoNo correspondehttp://sgc.anlis.gob.ar/oai/biblioteca@anlis.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:a2025-09-04 11:15:47.615Sistema de Gestión del Conocimiento ANLIS MALBRÁN - Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"false
dc.title.none.fl_str_mv Molecular identification and characterization of two proposed new enterovirus serotypes, EV74 and EV75
title Molecular identification and characterization of two proposed new enterovirus serotypes, EV74 and EV75
spellingShingle Molecular identification and characterization of two proposed new enterovirus serotypes, EV74 and EV75
Oberste, M. Steven
Enterovirus
Enterovirus Humano B
Picornaviridae
title_short Molecular identification and characterization of two proposed new enterovirus serotypes, EV74 and EV75
title_full Molecular identification and characterization of two proposed new enterovirus serotypes, EV74 and EV75
title_fullStr Molecular identification and characterization of two proposed new enterovirus serotypes, EV74 and EV75
title_full_unstemmed Molecular identification and characterization of two proposed new enterovirus serotypes, EV74 and EV75
title_sort Molecular identification and characterization of two proposed new enterovirus serotypes, EV74 and EV75
dc.creator.none.fl_str_mv Oberste, M. Steven
Michele, Suzanne M.
Maher, Kaija
Schnurr, David
Cisterna, Daniel
Junttila, Nina
Uddin, Moyez
Chomel, Jean-Jacques
Lau, Chi-Shan
Ridha, Walid
Al-Busaidy, Suleiman
Norder, Helene
Magnius, Lars O.
Pallansch, Mark A.
author Oberste, M. Steven
author_facet Oberste, M. Steven
Michele, Suzanne M.
Maher, Kaija
Schnurr, David
Cisterna, Daniel
Junttila, Nina
Uddin, Moyez
Chomel, Jean-Jacques
Lau, Chi-Shan
Ridha, Walid
Al-Busaidy, Suleiman
Norder, Helene
Magnius, Lars O.
Pallansch, Mark A.
author_role author
author2 Michele, Suzanne M.
Maher, Kaija
Schnurr, David
Cisterna, Daniel
Junttila, Nina
Uddin, Moyez
Chomel, Jean-Jacques
Lau, Chi-Shan
Ridha, Walid
Al-Busaidy, Suleiman
Norder, Helene
Magnius, Lars O.
Pallansch, Mark A.
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Enterovirus
Enterovirus Humano B
Picornaviridae
topic Enterovirus
Enterovirus Humano B
Picornaviridae
dc.description.none.fl_txt_mv Fil: Oberste, M. Steven. Centers for Disease Control and Prevention. Respiratory and Enteric Viruses Branch; Estados Unidos.
Fil: Michele, Suzanne M. Centers for Disease Control and Prevention. Respiratory and Enteric Viruses Branch; Estados Unidos.
Fil: Maher, Kaija. Centers for Disease Control and Prevention. Respiratory and Enteric Viruses Branch; Estados Unidos.
Fil: Schnurr, David. California Department of Health Services. Viral and Rickettsial Disease Laboratory; Estados Unidos.
Fil: Cisterna, Daniel. ANLIS Dr.C.G.Malbrán. Instituto Nacional de Enfermedades Infecciosas; Argentina.
Fil: Junttila, Nina. Swedish Institute for Disease Control. Department of Virology; Suecia.
Fil: Uddin, Moyez. Institute of Public Health; Bangladesh.
Fil: Chomel, Jean-Jacques. Centre National de Référence des Entérovirus; Francia.
Fil: Lau, Chi-Shan. Queen Mary Hospital. Department of Health; China.
Fil: Ridha, Walid. National Polio Laboratory; Irak.
Fil: Al-Busaidy, Suleiman. Ministry of Health. Department of Laboratories; Oman.
Fil: Norder, Helene. Swedish Institute for Disease Control. Department of Virology; Suecia.
Fil: Magnius, Lars O. Swedish Institute for Disease Control. Department of Virology; Suecia.
Fil: Pallansch, Mark A. Centers for Disease Control and Prevention. Respiratory and Enteric Viruses Branch; Estados Unidos.
Sequencing of the gene that encodes the capsid protein VP1 has been used as a surrogate for antigenic typing in order to distinguish enterovirus serotypes; three new serotypes were identified recently by this method. In this study, 14 enterovirus isolates from six countries were characterized as members of two new types within the species Human enterovirus B, based on sequencing of the complete capsid-encoding (P1) region. Isolates within each of these two types differed significantly from one another and from all other known enterovirus serotypes on the basis of sequences that encode either VP1 alone or the entire P1 region. Members of each type were greater than or equal to 77(.)2% identical to one another (89(.)5% amino acid identity) in VP1, but members of the two different types differed from one another and from other enteroviruses by greater than or equal to 31% in nucleotide sequence (25% amino acid sequence difference), indicating that the two groups represent separate new candidate enterovirus types. The complete P1 sequences differed from those of all other enterovirus serotypes by greater than or equal to 31% (26% amino acid sequence difference), but were highly conserved within a serotype (< 8% amino acid sequence difference). Phylogenetic analyses demonstrated that isolates of the same serotype were monophyletic in both VP1 and the capsid as a whole, as shown previously for other enterovirus serotypes. This paper proposes that these 14 isolates should be classified as members of two new human enterovirus types, enteroviruses 74 and 75 (EV74 and EV75).
description Fil: Oberste, M. Steven. Centers for Disease Control and Prevention. Respiratory and Enteric Viruses Branch; Estados Unidos.
publishDate 2004
dc.date.none.fl_str_mv 2004
dc.type.none.fl_str_mv info:ar-repo/semantics/articulo
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv 0022-1317
http://sgc.anlis.gob.ar/handle/123456789/396
http://vir.sgmjournals.org/content/85/11/3205.full.pdf
10.1099/vir.0.80148-0
identifier_str_mv 0022-1317
10.1099/vir.0.80148-0
url http://sgc.anlis.gob.ar/handle/123456789/396
http://vir.sgmjournals.org/content/85/11/3205.full.pdf
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv The Journal of general virology
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv Journal of General Virology 2004;85(11):3205-3212
reponame:Sistema de Gestión del Conocimiento ANLIS MALBRÁN
instname:Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"
instacron:ANLIS
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collection Sistema de Gestión del Conocimiento ANLIS MALBRÁN
instname_str Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"
instacron_str ANLIS
institution ANLIS
repository.name.fl_str_mv Sistema de Gestión del Conocimiento ANLIS MALBRÁN - Administración Nacional de Laboratorios e Institutos de Salud "Dr. Carlos G. Malbrán"
repository.mail.fl_str_mv biblioteca@anlis.gov.ar
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