Sulfated Zirconia: An Efficient and Reusable Heterogeneous Catalyst in the Friedel-Crafts Acylation Reaction of 3-Methylindole

Autores
Vargas, Darío Andrés; Méndez, Leticia Jesica; Cánepa, Alicia Susana; Bravo, Rodolfo Daniel
Año de publicación
2017
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
An efficient process for the Friedel–Crafts acylation of 3-methylindole with acid anhydrides in the presence of sulfated zirconia was developed. This catalyst shows excellent catalytic activity with good conversion and selectivity towards formation of the products of 2-acylation (3-methyl-1H-indol-2-yl)ketones. Other advantages related to this process are the simple work-up procedure and smaller production of chemical waste. The catalyst was easily recycled and reused with a minimal loss in activity through three reaction cycles. The catalyst was characterized by FT-IR spectroscopy, X-Ray diffraction and superficial acidity.
Centro de Estudios de Compuestos Orgánicos
Centro de Investigación y Desarrollo en Ciencias Aplicadas
Materia
Química
Sulfated zirconia
3-Methylindole
Ketones
Recyclability
Acylation reaction
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/118678
Acceder
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oai_identifier_str oai:sedici.unlp.edu.ar:10915/118678
network_acronym_str SEDICI
repository_id_str 1329
network_name_str SEDICI (UNLP)
spelling Sulfated Zirconia: An Efficient and Reusable Heterogeneous Catalyst in the Friedel-Crafts Acylation Reaction of 3-MethylindoleVargas, Darío AndrésMéndez, Leticia JesicaCánepa, Alicia SusanaBravo, Rodolfo DanielQuímicaSulfated zirconia3-MethylindoleKetonesRecyclabilityAcylation reactionAn efficient process for the Friedel–Crafts acylation of 3-methylindole with acid anhydrides in the presence of sulfated zirconia was developed. This catalyst shows excellent catalytic activity with good conversion and selectivity towards formation of the products of 2-acylation (3-methyl-1H-indol-2-yl)ketones. Other advantages related to this process are the simple work-up procedure and smaller production of chemical waste. The catalyst was easily recycled and reused with a minimal loss in activity through three reaction cycles. The catalyst was characterized by FT-IR spectroscopy, X-Ray diffraction and superficial acidity.Centro de Estudios de Compuestos OrgánicosCentro de Investigación y Desarrollo en Ciencias Aplicadas2017info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://sedici.unlp.edu.ar/handle/10915/118678enginfo:eu-repo/semantics/altIdentifier/issn/1572-879Xinfo:eu-repo/semantics/altIdentifier/doi/10.1007/s10562-017-2057-xinfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/4.0/Creative Commons Attribution 4.0 International (CC BY 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-29T11:27:55Zoai:sedici.unlp.edu.ar:10915/118678Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-29 11:27:55.926SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv Sulfated Zirconia: An Efficient and Reusable Heterogeneous Catalyst in the Friedel-Crafts Acylation Reaction of 3-Methylindole
title Sulfated Zirconia: An Efficient and Reusable Heterogeneous Catalyst in the Friedel-Crafts Acylation Reaction of 3-Methylindole
spellingShingle Sulfated Zirconia: An Efficient and Reusable Heterogeneous Catalyst in the Friedel-Crafts Acylation Reaction of 3-Methylindole
Vargas, Darío Andrés
Química
Sulfated zirconia
3-Methylindole
Ketones
Recyclability
Acylation reaction
title_short Sulfated Zirconia: An Efficient and Reusable Heterogeneous Catalyst in the Friedel-Crafts Acylation Reaction of 3-Methylindole
title_full Sulfated Zirconia: An Efficient and Reusable Heterogeneous Catalyst in the Friedel-Crafts Acylation Reaction of 3-Methylindole
title_fullStr Sulfated Zirconia: An Efficient and Reusable Heterogeneous Catalyst in the Friedel-Crafts Acylation Reaction of 3-Methylindole
title_full_unstemmed Sulfated Zirconia: An Efficient and Reusable Heterogeneous Catalyst in the Friedel-Crafts Acylation Reaction of 3-Methylindole
title_sort Sulfated Zirconia: An Efficient and Reusable Heterogeneous Catalyst in the Friedel-Crafts Acylation Reaction of 3-Methylindole
dc.creator.none.fl_str_mv Vargas, Darío Andrés
Méndez, Leticia Jesica
Cánepa, Alicia Susana
Bravo, Rodolfo Daniel
author Vargas, Darío Andrés
author_facet Vargas, Darío Andrés
Méndez, Leticia Jesica
Cánepa, Alicia Susana
Bravo, Rodolfo Daniel
author_role author
author2 Méndez, Leticia Jesica
Cánepa, Alicia Susana
Bravo, Rodolfo Daniel
author2_role author
author
author
dc.subject.none.fl_str_mv Química
Sulfated zirconia
3-Methylindole
Ketones
Recyclability
Acylation reaction
topic Química
Sulfated zirconia
3-Methylindole
Ketones
Recyclability
Acylation reaction
dc.description.none.fl_txt_mv An efficient process for the Friedel–Crafts acylation of 3-methylindole with acid anhydrides in the presence of sulfated zirconia was developed. This catalyst shows excellent catalytic activity with good conversion and selectivity towards formation of the products of 2-acylation (3-methyl-1H-indol-2-yl)ketones. Other advantages related to this process are the simple work-up procedure and smaller production of chemical waste. The catalyst was easily recycled and reused with a minimal loss in activity through three reaction cycles. The catalyst was characterized by FT-IR spectroscopy, X-Ray diffraction and superficial acidity.
Centro de Estudios de Compuestos Orgánicos
Centro de Investigación y Desarrollo en Ciencias Aplicadas
description An efficient process for the Friedel–Crafts acylation of 3-methylindole with acid anhydrides in the presence of sulfated zirconia was developed. This catalyst shows excellent catalytic activity with good conversion and selectivity towards formation of the products of 2-acylation (3-methyl-1H-indol-2-yl)ketones. Other advantages related to this process are the simple work-up procedure and smaller production of chemical waste. The catalyst was easily recycled and reused with a minimal loss in activity through three reaction cycles. The catalyst was characterized by FT-IR spectroscopy, X-Ray diffraction and superficial acidity.
publishDate 2017
dc.date.none.fl_str_mv 2017
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Articulo
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/118678
url http://sedici.unlp.edu.ar/handle/10915/118678
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/issn/1572-879X
info:eu-repo/semantics/altIdentifier/doi/10.1007/s10562-017-2057-x
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/4.0/
Creative Commons Attribution 4.0 International (CC BY 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
Creative Commons Attribution 4.0 International (CC BY 4.0)
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:SEDICI (UNLP)
instname:Universidad Nacional de La Plata
instacron:UNLP
reponame_str SEDICI (UNLP)
collection SEDICI (UNLP)
instname_str Universidad Nacional de La Plata
instacron_str UNLP
institution UNLP
repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
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