The kidney in aging

Autores
Ferder, Leon
Año de publicación
2007
Idioma
inglés
Tipo de recurso
reseña artículo
Estado
versión publicada
Descripción
Aging is a slow, inflammatory biological process that affects many organs of which the kidney is one of the main targets. Aging is associated with a decline in renal function coincident with a progressive loss of nephrons, with glomerular and tubulointerstitial scarring. These changes begin in the fourth decade of life and accelerate between the 5th and 6th decade, resulting in alterations in glomerular and tubular function, systemic hemodynamics and body homeostasis. While aging-related changes begin in mid-life, most of the discussion will revolve around the management of the older population, defined as > 65 years of age. It is important to realize that aging-associated renal disease may not be an inevitable consequence of life. Some subjects do not show age-related decline in GFR, and in some populations hypertension does not increase with aging, the latter occurring primarily in non-Westernized groups habitually on low sodium diets. This has led some to hypothesize that aging-associated renal disease may be an active process that is potentially preventable.
Sociedad Argentina de Fisiología
Materia
Ciencias Médicas
Aging
Renal disease
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/147321
Acceder
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spelling The kidney in agingFerder, LeonCiencias MédicasAgingRenal diseaseAging is a slow, inflammatory biological process that affects many organs of which the kidney is one of the main targets. Aging is associated with a decline in renal function coincident with a progressive loss of nephrons, with glomerular and tubulointerstitial scarring. These changes begin in the fourth decade of life and accelerate between the 5th and 6th decade, resulting in alterations in glomerular and tubular function, systemic hemodynamics and body homeostasis. While aging-related changes begin in mid-life, most of the discussion will revolve around the management of the older population, defined as > 65 years of age. It is important to realize that aging-associated renal disease may not be an inevitable consequence of life. Some subjects do not show age-related decline in GFR, and in some populations hypertension does not increase with aging, the latter occurring primarily in non-Westernized groups habitually on low sodium diets. This has led some to hypothesize that aging-associated renal disease may be an active process that is potentially preventable.Sociedad Argentina de Fisiología2007-02info:eu-repo/semantics/reviewinfo:eu-repo/semantics/publishedVersionRevisionhttp://purl.org/coar/resource_type/c_dcae04bcinfo:ar-repo/semantics/resenaArticuloapplication/pdf43-47http://sedici.unlp.edu.ar/handle/10915/147321enginfo:eu-repo/semantics/altIdentifier/url/https://pmr.safisiol.org.ar/wp-content/uploads/2022/08/vol2_n7_february.pdfinfo:eu-repo/semantics/altIdentifier/issn/1669-5410info:eu-repo/semantics/altIdentifier/issn/1669-5402info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/4.0/Creative Commons Attribution 4.0 International (CC BY 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-29T11:37:37Zoai:sedici.unlp.edu.ar:10915/147321Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-29 11:37:37.711SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv The kidney in aging
title The kidney in aging
spellingShingle The kidney in aging
Ferder, Leon
Ciencias Médicas
Aging
Renal disease
title_short The kidney in aging
title_full The kidney in aging
title_fullStr The kidney in aging
title_full_unstemmed The kidney in aging
title_sort The kidney in aging
dc.creator.none.fl_str_mv Ferder, Leon
author Ferder, Leon
author_facet Ferder, Leon
author_role author
dc.subject.none.fl_str_mv Ciencias Médicas
Aging
Renal disease
topic Ciencias Médicas
Aging
Renal disease
dc.description.none.fl_txt_mv Aging is a slow, inflammatory biological process that affects many organs of which the kidney is one of the main targets. Aging is associated with a decline in renal function coincident with a progressive loss of nephrons, with glomerular and tubulointerstitial scarring. These changes begin in the fourth decade of life and accelerate between the 5th and 6th decade, resulting in alterations in glomerular and tubular function, systemic hemodynamics and body homeostasis. While aging-related changes begin in mid-life, most of the discussion will revolve around the management of the older population, defined as > 65 years of age. It is important to realize that aging-associated renal disease may not be an inevitable consequence of life. Some subjects do not show age-related decline in GFR, and in some populations hypertension does not increase with aging, the latter occurring primarily in non-Westernized groups habitually on low sodium diets. This has led some to hypothesize that aging-associated renal disease may be an active process that is potentially preventable.
Sociedad Argentina de Fisiología
description Aging is a slow, inflammatory biological process that affects many organs of which the kidney is one of the main targets. Aging is associated with a decline in renal function coincident with a progressive loss of nephrons, with glomerular and tubulointerstitial scarring. These changes begin in the fourth decade of life and accelerate between the 5th and 6th decade, resulting in alterations in glomerular and tubular function, systemic hemodynamics and body homeostasis. While aging-related changes begin in mid-life, most of the discussion will revolve around the management of the older population, defined as > 65 years of age. It is important to realize that aging-associated renal disease may not be an inevitable consequence of life. Some subjects do not show age-related decline in GFR, and in some populations hypertension does not increase with aging, the latter occurring primarily in non-Westernized groups habitually on low sodium diets. This has led some to hypothesize that aging-associated renal disease may be an active process that is potentially preventable.
publishDate 2007
dc.date.none.fl_str_mv 2007-02
dc.type.none.fl_str_mv info:eu-repo/semantics/review
info:eu-repo/semantics/publishedVersion
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info:ar-repo/semantics/resenaArticulo
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status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/147321
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dc.language.none.fl_str_mv eng
language eng
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info:eu-repo/semantics/altIdentifier/issn/1669-5410
info:eu-repo/semantics/altIdentifier/issn/1669-5402
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/4.0/
Creative Commons Attribution 4.0 International (CC BY 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
Creative Commons Attribution 4.0 International (CC BY 4.0)
dc.format.none.fl_str_mv application/pdf
43-47
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instname:Universidad Nacional de La Plata
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reponame_str SEDICI (UNLP)
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instname_str Universidad Nacional de La Plata
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repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
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