Effect of silver nanoparticles on the photophysics of riboflavin: consequences on the ROS generation

Autores
Rivas Aiello, María Belén; Romero, Juan José; Bertolotti, Sonia G.; González, Mónica Cristina; Mártire, Daniel Osvaldo
Año de publicación
2016
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Metal-enhanced singlet oxygen, O₂(¹Δg), generation is a desirable effect to augment the amount of O₂(¹Δg) produced upon irradiation of organic sensitizers. Herein, we employed pectin for stabilizing 9 nm silver nanoparticles and showed that these particles are able to form a ground-sate complex with riboflavin (Rf). Pump–probe transient absorption spectroscopy and laser flash-photolysis experiments proved that the excited state of the riboflavin–Ag complex feeds the triplet state of the sensitizer, which results in an enhanced intersystem crossing process. The higher amounts of riboflavin triplet states formed in the presence of the nanoparticles result in higher yields of singlet oxygen and hydrogen peroxide produced in the irradiated colloidal suspensions. As a result, not only the effect on singlet oxygen but also the effect on superoxide radical ion should contribute to a better performance of Riboflavin as a sensitizer applied to the photodynamic therapy of tumors.
Este documento tiene una corrección (ver documento relacionado).
Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas
Materia
Física
Química
Silver Nanoparticles
Photophysics of Riboflavin
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/145978
Acceder
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oai_identifier_str oai:sedici.unlp.edu.ar:10915/145978
network_acronym_str SEDICI
repository_id_str 1329
network_name_str SEDICI (UNLP)
spelling Effect of silver nanoparticles on the photophysics of riboflavin: consequences on the ROS generationRivas Aiello, María BelénRomero, Juan JoséBertolotti, Sonia G.González, Mónica CristinaMártire, Daniel OsvaldoFísicaQuímicaSilver NanoparticlesPhotophysics of RiboflavinMetal-enhanced singlet oxygen, O₂(¹Δg), generation is a desirable effect to augment the amount of O₂(¹Δg) produced upon irradiation of organic sensitizers. Herein, we employed pectin for stabilizing 9 nm silver nanoparticles and showed that these particles are able to form a ground-sate complex with riboflavin (Rf). Pump–probe transient absorption spectroscopy and laser flash-photolysis experiments proved that the excited state of the riboflavin–Ag complex feeds the triplet state of the sensitizer, which results in an enhanced intersystem crossing process. The higher amounts of riboflavin triplet states formed in the presence of the nanoparticles result in higher yields of singlet oxygen and hydrogen peroxide produced in the irradiated colloidal suspensions. As a result, not only the effect on singlet oxygen but also the effect on superoxide radical ion should contribute to a better performance of Riboflavin as a sensitizer applied to the photodynamic therapy of tumors.Este documento tiene una corrección (ver documento relacionado).Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas2016-09-14info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdf21975-21975http://sedici.unlp.edu.ar/handle/10915/145978enginfo:eu-repo/semantics/altIdentifier/issn/1932-7447info:eu-repo/semantics/altIdentifier/issn/1932-7455info:eu-repo/semantics/altIdentifier/doi/10.1021/acs.jpcc.6b06385info:eu-repo/semantics/reference/hdl/10915/145979info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-29T11:32:26Zoai:sedici.unlp.edu.ar:10915/145978Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-29 11:32:26.976SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv Effect of silver nanoparticles on the photophysics of riboflavin: consequences on the ROS generation
title Effect of silver nanoparticles on the photophysics of riboflavin: consequences on the ROS generation
spellingShingle Effect of silver nanoparticles on the photophysics of riboflavin: consequences on the ROS generation
Rivas Aiello, María Belén
Física
Química
Silver Nanoparticles
Photophysics of Riboflavin
title_short Effect of silver nanoparticles on the photophysics of riboflavin: consequences on the ROS generation
title_full Effect of silver nanoparticles on the photophysics of riboflavin: consequences on the ROS generation
title_fullStr Effect of silver nanoparticles on the photophysics of riboflavin: consequences on the ROS generation
title_full_unstemmed Effect of silver nanoparticles on the photophysics of riboflavin: consequences on the ROS generation
title_sort Effect of silver nanoparticles on the photophysics of riboflavin: consequences on the ROS generation
dc.creator.none.fl_str_mv Rivas Aiello, María Belén
Romero, Juan José
Bertolotti, Sonia G.
González, Mónica Cristina
Mártire, Daniel Osvaldo
author Rivas Aiello, María Belén
author_facet Rivas Aiello, María Belén
Romero, Juan José
Bertolotti, Sonia G.
González, Mónica Cristina
Mártire, Daniel Osvaldo
author_role author
author2 Romero, Juan José
Bertolotti, Sonia G.
González, Mónica Cristina
Mártire, Daniel Osvaldo
author2_role author
author
author
author
dc.subject.none.fl_str_mv Física
Química
Silver Nanoparticles
Photophysics of Riboflavin
topic Física
Química
Silver Nanoparticles
Photophysics of Riboflavin
dc.description.none.fl_txt_mv Metal-enhanced singlet oxygen, O₂(¹Δg), generation is a desirable effect to augment the amount of O₂(¹Δg) produced upon irradiation of organic sensitizers. Herein, we employed pectin for stabilizing 9 nm silver nanoparticles and showed that these particles are able to form a ground-sate complex with riboflavin (Rf). Pump–probe transient absorption spectroscopy and laser flash-photolysis experiments proved that the excited state of the riboflavin–Ag complex feeds the triplet state of the sensitizer, which results in an enhanced intersystem crossing process. The higher amounts of riboflavin triplet states formed in the presence of the nanoparticles result in higher yields of singlet oxygen and hydrogen peroxide produced in the irradiated colloidal suspensions. As a result, not only the effect on singlet oxygen but also the effect on superoxide radical ion should contribute to a better performance of Riboflavin as a sensitizer applied to the photodynamic therapy of tumors.
Este documento tiene una corrección (ver documento relacionado).
Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas
description Metal-enhanced singlet oxygen, O₂(¹Δg), generation is a desirable effect to augment the amount of O₂(¹Δg) produced upon irradiation of organic sensitizers. Herein, we employed pectin for stabilizing 9 nm silver nanoparticles and showed that these particles are able to form a ground-sate complex with riboflavin (Rf). Pump–probe transient absorption spectroscopy and laser flash-photolysis experiments proved that the excited state of the riboflavin–Ag complex feeds the triplet state of the sensitizer, which results in an enhanced intersystem crossing process. The higher amounts of riboflavin triplet states formed in the presence of the nanoparticles result in higher yields of singlet oxygen and hydrogen peroxide produced in the irradiated colloidal suspensions. As a result, not only the effect on singlet oxygen but also the effect on superoxide radical ion should contribute to a better performance of Riboflavin as a sensitizer applied to the photodynamic therapy of tumors.
publishDate 2016
dc.date.none.fl_str_mv 2016-09-14
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Articulo
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/145978
url http://sedici.unlp.edu.ar/handle/10915/145978
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/issn/1932-7447
info:eu-repo/semantics/altIdentifier/issn/1932-7455
info:eu-repo/semantics/altIdentifier/doi/10.1021/acs.jpcc.6b06385
info:eu-repo/semantics/reference/hdl/10915/145979
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv application/pdf
21975-21975
dc.source.none.fl_str_mv reponame:SEDICI (UNLP)
instname:Universidad Nacional de La Plata
instacron:UNLP
reponame_str SEDICI (UNLP)
collection SEDICI (UNLP)
instname_str Universidad Nacional de La Plata
instacron_str UNLP
institution UNLP
repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
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score 13.069144

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