Ploidy in bone marrow cells from healthy donors: a MAC (morphology antibody chromosomes) study

Autores
Larramendy, Marcelo Luis; Nylund, S. J.; Wessman, M.; Ruutu, T.; Knuutila, S.
Año de publicación
1994
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The ploidy of human bone marrow cells belonging to the megakaryocytic, granulocytic-monocytic and erythrocytic lineages was studied by in situ hybridization using the biotin-labelled Y chromosome-specific DNA probe pY431 and the chromosome 1-specific probe pUC1.77 on cells identified morphologically and immunologically by the MAC procedure. Cells of the granulocytic-monocytic and erythrocytic lineages were seen to be 2N in ploidy, whereas the ploidy of the megakaryocytic lineage ranged from 2N to 32N, with the ploidy classes 4N and 8N being predominant. The frequency of megakaryocytes with 2N chromosomes was also high.
Facultad de Ciencias Naturales y Museo
Materia
Ciencias Naturales
Ploidy
Bone Marrow Cells
Morphology antibody chromosomes technique
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/122969
Acceder
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oai_identifier_str oai:sedici.unlp.edu.ar:10915/122969
network_acronym_str SEDICI
repository_id_str 1329
network_name_str SEDICI (UNLP)
spelling Ploidy in bone marrow cells from healthy donors: a MAC (morphology antibody chromosomes) studyLarramendy, Marcelo LuisNylund, S. J.Wessman, M.Ruutu, T.Knuutila, S.Ciencias NaturalesPloidyBone Marrow CellsMorphology antibody chromosomes techniqueThe ploidy of human bone marrow cells belonging to the megakaryocytic, granulocytic-monocytic and erythrocytic lineages was studied by in situ hybridization using the biotin-labelled Y chromosome-specific DNA probe pY431 and the chromosome 1-specific probe pUC1.77 on cells identified morphologically and immunologically by the MAC procedure. Cells of the granulocytic-monocytic and erythrocytic lineages were seen to be 2N in ploidy, whereas the ploidy of the megakaryocytic lineage ranged from 2N to 32N, with the ploidy classes 4N and 8N being predominant. The frequency of megakaryocytes with 2N chromosomes was also high.Facultad de Ciencias Naturales y Museo1994info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdf203-206http://sedici.unlp.edu.ar/handle/10915/122969enginfo:eu-repo/semantics/altIdentifier/issn/0007-1048info:eu-repo/semantics/altIdentifier/issn/1365-2141info:eu-repo/semantics/altIdentifier/pmid/8011532info:eu-repo/semantics/altIdentifier/doi/10.1111/j.1365-2141.1994.tb03279.xinfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-29T11:29:14Zoai:sedici.unlp.edu.ar:10915/122969Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-29 11:29:15.065SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv Ploidy in bone marrow cells from healthy donors: a MAC (morphology antibody chromosomes) study
title Ploidy in bone marrow cells from healthy donors: a MAC (morphology antibody chromosomes) study
spellingShingle Ploidy in bone marrow cells from healthy donors: a MAC (morphology antibody chromosomes) study
Larramendy, Marcelo Luis
Ciencias Naturales
Ploidy
Bone Marrow Cells
Morphology antibody chromosomes technique
title_short Ploidy in bone marrow cells from healthy donors: a MAC (morphology antibody chromosomes) study
title_full Ploidy in bone marrow cells from healthy donors: a MAC (morphology antibody chromosomes) study
title_fullStr Ploidy in bone marrow cells from healthy donors: a MAC (morphology antibody chromosomes) study
title_full_unstemmed Ploidy in bone marrow cells from healthy donors: a MAC (morphology antibody chromosomes) study
title_sort Ploidy in bone marrow cells from healthy donors: a MAC (morphology antibody chromosomes) study
dc.creator.none.fl_str_mv Larramendy, Marcelo Luis
Nylund, S. J.
Wessman, M.
Ruutu, T.
Knuutila, S.
author Larramendy, Marcelo Luis
author_facet Larramendy, Marcelo Luis
Nylund, S. J.
Wessman, M.
Ruutu, T.
Knuutila, S.
author_role author
author2 Nylund, S. J.
Wessman, M.
Ruutu, T.
Knuutila, S.
author2_role author
author
author
author
dc.subject.none.fl_str_mv Ciencias Naturales
Ploidy
Bone Marrow Cells
Morphology antibody chromosomes technique
topic Ciencias Naturales
Ploidy
Bone Marrow Cells
Morphology antibody chromosomes technique
dc.description.none.fl_txt_mv The ploidy of human bone marrow cells belonging to the megakaryocytic, granulocytic-monocytic and erythrocytic lineages was studied by in situ hybridization using the biotin-labelled Y chromosome-specific DNA probe pY431 and the chromosome 1-specific probe pUC1.77 on cells identified morphologically and immunologically by the MAC procedure. Cells of the granulocytic-monocytic and erythrocytic lineages were seen to be 2N in ploidy, whereas the ploidy of the megakaryocytic lineage ranged from 2N to 32N, with the ploidy classes 4N and 8N being predominant. The frequency of megakaryocytes with 2N chromosomes was also high.
Facultad de Ciencias Naturales y Museo
description The ploidy of human bone marrow cells belonging to the megakaryocytic, granulocytic-monocytic and erythrocytic lineages was studied by in situ hybridization using the biotin-labelled Y chromosome-specific DNA probe pY431 and the chromosome 1-specific probe pUC1.77 on cells identified morphologically and immunologically by the MAC procedure. Cells of the granulocytic-monocytic and erythrocytic lineages were seen to be 2N in ploidy, whereas the ploidy of the megakaryocytic lineage ranged from 2N to 32N, with the ploidy classes 4N and 8N being predominant. The frequency of megakaryocytes with 2N chromosomes was also high.
publishDate 1994
dc.date.none.fl_str_mv 1994
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Articulo
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/122969
url http://sedici.unlp.edu.ar/handle/10915/122969
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/issn/0007-1048
info:eu-repo/semantics/altIdentifier/issn/1365-2141
info:eu-repo/semantics/altIdentifier/pmid/8011532
info:eu-repo/semantics/altIdentifier/doi/10.1111/j.1365-2141.1994.tb03279.x
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv application/pdf
203-206
dc.source.none.fl_str_mv reponame:SEDICI (UNLP)
instname:Universidad Nacional de La Plata
instacron:UNLP
reponame_str SEDICI (UNLP)
collection SEDICI (UNLP)
instname_str Universidad Nacional de La Plata
instacron_str UNLP
institution UNLP
repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
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score 13.070432

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