Consequences of smoking during pregnancy for mother and child

Autores
Marín, Gustavo Horacio; Delgado, Liliana; Sager, Gustavo; Visentín, Silvana Beatriz; Azzaro, Sebastiana; Tozzi, Mabel
Año de publicación
2003
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Objective: to evaluate the consequences of maternal smoking. Methods: a prospective study of 1.103 pregnant women. A survey in the state Hospital San Martin, de La Plata, Buenos Aires determined general data. Newborn and placenta data were also reported. Mother and child cord samples were obtained to determine blood elements and flow cytometry analysis of lymphocyte subsets performed. Data from smoking (S) and non-smoking (NS) groups were evaluated through relative risk, chi square and Student's t test. Results: of all patients, 887 were NS and 226 said they smoked over five-cigarettes/day (S). The S group showed a higher probability of premature deliveries when compared to the NS group, with newborns weighing under 2,5kg, small in relation to gestational age, with Apgar scores at the 5th minute under six and hyaline membrane syndrome; intrauterine death risk was higher in this group who attended less medical appointments than scheduled. Umbilical cord blood analysis indicated lower reticulocyte index for S mothers, neutrophil count and CD4/CD8 ratio and increased erythroblast, eosinophil, basophil, total and CD8+T lymphocyte counts. Conclusions: data could explain the observations by other authors related to an increased incidence of allergy and infections in newborns caused by maternal smoking.
Objetivos: avaliar as conseqüências para a mãe e para o filho do hábito de fumar durante a gestação. Métodos: é um estudo prospectivo com 1.103 gestantes a partir de inquérito em mulheres atendidas no Hospital San Martin de La Plata, Buenos Aires. Amostras foram obtidas para determinação de elementos sangüineos e citometria de fluxo. O risco relativo entre fumantes e não fumantes foi calculado e se usou ainda o c2 e o teste "t" de Student. Resultados: 887 gestantes eram não fumantes e 226 não fumantes. O grupo fumante teve maior probalidade do que o não fumante para: partos prematuros, recém-natos com peso baixo, pequenos em relação à idade gestacional, maior risco de morte intra-uterina, Apgar abaixo de seis aos cinco minutos, síndrome da membrana hialina, menor número de consultas do que as programadas. A análise do sangue do cordão umbelical mostrou nas fumantes: menor número de reticulocitos, diminuição da relação CD4/CD8 e maior número de eritroblastos, eosinófilos, basófilos, linfócitos totais e CD8. Conclusões: os dados poderiam explicar observações de outros autores indicando maior incidência de alergias e infecções em recém-natos causadas por tabagismo materno.
Facultad de Ciencias Médicas
Materia
Medicina
Pregnancy
Smoking
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/123044

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oai_identifier_str oai:sedici.unlp.edu.ar:10915/123044
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network_name_str SEDICI (UNLP)
spelling Consequences of smoking during pregnancy for mother and childEfeitos do tabagismo na gestação para a mãe e para a criançaMarín, Gustavo HoracioDelgado, LilianaSager, GustavoVisentín, Silvana BeatrizAzzaro, SebastianaTozzi, MabelMedicinaPregnancySmokingObjective: to evaluate the consequences of maternal smoking. Methods: a prospective study of 1.103 pregnant women. A survey in the state Hospital San Martin, de La Plata, Buenos Aires determined general data. Newborn and placenta data were also reported. Mother and child cord samples were obtained to determine blood elements and flow cytometry analysis of lymphocyte subsets performed. Data from smoking (S) and non-smoking (NS) groups were evaluated through relative risk, chi square and Student's t test. Results: of all patients, 887 were NS and 226 said they smoked over five-cigarettes/day (S). The S group showed a higher probability of premature deliveries when compared to the NS group, with newborns weighing under 2,5kg, small in relation to gestational age, with Apgar scores at the 5th minute under six and hyaline membrane syndrome; intrauterine death risk was higher in this group who attended less medical appointments than scheduled. Umbilical cord blood analysis indicated lower reticulocyte index for S mothers, neutrophil count and CD4/CD8 ratio and increased erythroblast, eosinophil, basophil, total and CD8+T lymphocyte counts. Conclusions: data could explain the observations by other authors related to an increased incidence of allergy and infections in newborns caused by maternal smoking.Objetivos: avaliar as conseqüências para a mãe e para o filho do hábito de fumar durante a gestação. Métodos: é um estudo prospectivo com 1.103 gestantes a partir de inquérito em mulheres atendidas no Hospital San Martin de La Plata, Buenos Aires. Amostras foram obtidas para determinação de elementos sangüineos e citometria de fluxo. O risco relativo entre fumantes e não fumantes foi calculado e se usou ainda o c2 e o teste "t" de Student. Resultados: 887 gestantes eram não fumantes e 226 não fumantes. O grupo fumante teve maior probalidade do que o não fumante para: partos prematuros, recém-natos com peso baixo, pequenos em relação à idade gestacional, maior risco de morte intra-uterina, Apgar abaixo de seis aos cinco minutos, síndrome da membrana hialina, menor número de consultas do que as programadas. A análise do sangue do cordão umbelical mostrou nas fumantes: menor número de reticulocitos, diminuição da relação CD4/CD8 e maior número de eritroblastos, eosinófilos, basófilos, linfócitos totais e CD8. Conclusões: os dados poderiam explicar observações de outros autores indicando maior incidência de alergias e infecções em recém-natos causadas por tabagismo materno.Facultad de Ciencias Médicas2003-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdf159-164http://sedici.unlp.edu.ar/handle/10915/123044enginfo:eu-repo/semantics/altIdentifier/issn/1806-9304info:eu-repo/semantics/altIdentifier/doi/10.1590/S1519-38292003000200005info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc/4.0/Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-29T11:29:23Zoai:sedici.unlp.edu.ar:10915/123044Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-29 11:29:24.028SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv Consequences of smoking during pregnancy for mother and child
Efeitos do tabagismo na gestação para a mãe e para a criança
title Consequences of smoking during pregnancy for mother and child
spellingShingle Consequences of smoking during pregnancy for mother and child
Marín, Gustavo Horacio
Medicina
Pregnancy
Smoking
title_short Consequences of smoking during pregnancy for mother and child
title_full Consequences of smoking during pregnancy for mother and child
title_fullStr Consequences of smoking during pregnancy for mother and child
title_full_unstemmed Consequences of smoking during pregnancy for mother and child
title_sort Consequences of smoking during pregnancy for mother and child
dc.creator.none.fl_str_mv Marín, Gustavo Horacio
Delgado, Liliana
Sager, Gustavo
Visentín, Silvana Beatriz
Azzaro, Sebastiana
Tozzi, Mabel
author Marín, Gustavo Horacio
author_facet Marín, Gustavo Horacio
Delgado, Liliana
Sager, Gustavo
Visentín, Silvana Beatriz
Azzaro, Sebastiana
Tozzi, Mabel
author_role author
author2 Delgado, Liliana
Sager, Gustavo
Visentín, Silvana Beatriz
Azzaro, Sebastiana
Tozzi, Mabel
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Medicina
Pregnancy
Smoking
topic Medicina
Pregnancy
Smoking
dc.description.none.fl_txt_mv Objective: to evaluate the consequences of maternal smoking. Methods: a prospective study of 1.103 pregnant women. A survey in the state Hospital San Martin, de La Plata, Buenos Aires determined general data. Newborn and placenta data were also reported. Mother and child cord samples were obtained to determine blood elements and flow cytometry analysis of lymphocyte subsets performed. Data from smoking (S) and non-smoking (NS) groups were evaluated through relative risk, chi square and Student's t test. Results: of all patients, 887 were NS and 226 said they smoked over five-cigarettes/day (S). The S group showed a higher probability of premature deliveries when compared to the NS group, with newborns weighing under 2,5kg, small in relation to gestational age, with Apgar scores at the 5th minute under six and hyaline membrane syndrome; intrauterine death risk was higher in this group who attended less medical appointments than scheduled. Umbilical cord blood analysis indicated lower reticulocyte index for S mothers, neutrophil count and CD4/CD8 ratio and increased erythroblast, eosinophil, basophil, total and CD8+T lymphocyte counts. Conclusions: data could explain the observations by other authors related to an increased incidence of allergy and infections in newborns caused by maternal smoking.
Objetivos: avaliar as conseqüências para a mãe e para o filho do hábito de fumar durante a gestação. Métodos: é um estudo prospectivo com 1.103 gestantes a partir de inquérito em mulheres atendidas no Hospital San Martin de La Plata, Buenos Aires. Amostras foram obtidas para determinação de elementos sangüineos e citometria de fluxo. O risco relativo entre fumantes e não fumantes foi calculado e se usou ainda o c2 e o teste "t" de Student. Resultados: 887 gestantes eram não fumantes e 226 não fumantes. O grupo fumante teve maior probalidade do que o não fumante para: partos prematuros, recém-natos com peso baixo, pequenos em relação à idade gestacional, maior risco de morte intra-uterina, Apgar abaixo de seis aos cinco minutos, síndrome da membrana hialina, menor número de consultas do que as programadas. A análise do sangue do cordão umbelical mostrou nas fumantes: menor número de reticulocitos, diminuição da relação CD4/CD8 e maior número de eritroblastos, eosinófilos, basófilos, linfócitos totais e CD8. Conclusões: os dados poderiam explicar observações de outros autores indicando maior incidência de alergias e infecções em recém-natos causadas por tabagismo materno.
Facultad de Ciencias Médicas
description Objective: to evaluate the consequences of maternal smoking. Methods: a prospective study of 1.103 pregnant women. A survey in the state Hospital San Martin, de La Plata, Buenos Aires determined general data. Newborn and placenta data were also reported. Mother and child cord samples were obtained to determine blood elements and flow cytometry analysis of lymphocyte subsets performed. Data from smoking (S) and non-smoking (NS) groups were evaluated through relative risk, chi square and Student's t test. Results: of all patients, 887 were NS and 226 said they smoked over five-cigarettes/day (S). The S group showed a higher probability of premature deliveries when compared to the NS group, with newborns weighing under 2,5kg, small in relation to gestational age, with Apgar scores at the 5th minute under six and hyaline membrane syndrome; intrauterine death risk was higher in this group who attended less medical appointments than scheduled. Umbilical cord blood analysis indicated lower reticulocyte index for S mothers, neutrophil count and CD4/CD8 ratio and increased erythroblast, eosinophil, basophil, total and CD8+T lymphocyte counts. Conclusions: data could explain the observations by other authors related to an increased incidence of allergy and infections in newborns caused by maternal smoking.
publishDate 2003
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