Biological Control of the Chagas Disease Vector <i>Triatoma infestans</i> with the Entomopathogenic Fungus <i>Beauveria bassiana</i> Combined with an Aggregation Cue: Field, Labora...

Autores
Forlani, Lucas; Pedrini, Nicolás; Girotti, Juan Roberto; Mijailovsky, Sergio Javier; Cardozo, Rubén M.; Gentile, Alberto G.; Hernández Suárez, Carlos M.; Rabinovich, Jorge Eduardo; Juárez, Marta Patricia
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Current Chagas disease vector control strategies, based on chemical insecticide spraying, are growingly threatened by the emergence of pyrethroid-resistant Triatoma infestans populations in the Gran Chaco region of South America. We have already shown that the entomopathogenic fungus Beauveria bassiana has the ability to breach the insect cuticle and is effective both against pyrethroid-susceptible and pyrethroid-resistant T. infestans, in laboratory as well as field assays. It is also known that T. infestans cuticle lipids play a major role as contact aggregation pheromones. We estimated the effectiveness of pheromone-based infection boxes containing B. bassiana spores to kill indoor bugs, and its effect on the vector population dynamics. Laboratory assays were performed to estimate the effect of fungal infection on female reproductive parameters. The effect of insect exuviae as an aggregation signal in the performance of the infection boxes was estimated both in the laboratory and in the field. We developed a stage-specific matrix model of T. infestans to describe the fungal infection effects on insect population dynamics, and to analyze the performance of the biopesticide device in vector biological control. The pheromone-containing infective box is a promising new tool against indoor populations of this Chagas disease vector, with the number of boxes per house being the main driver of the reduction of the total domestic bug population. This ecologically safe approach is the first proven alternative to chemical insecticides in the control of T. infestans. The advantageous reduction in vector population by delayed-action fungal biopesticides in a contained environment is here shown supported by mathematical modeling.
Instituto de Investigaciones Bioquímicas de La Plata
Facultad de Ciencias Médicas
Centro de Estudios Parasitológicos y de Vectores
Materia
Ciencias Médicas
Triatoma infestans
Beauveria bassiana
Chagas disease
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/86190
Acceder
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spelling Biological Control of the Chagas Disease Vector <i>Triatoma infestans</i> with the Entomopathogenic Fungus <i>Beauveria bassiana</i> Combined with an Aggregation Cue: Field, Laboratory and Mathematical Modeling AssessmentForlani, LucasPedrini, NicolásGirotti, Juan RobertoMijailovsky, Sergio JavierCardozo, Rubén M.Gentile, Alberto G.Hernández Suárez, Carlos M.Rabinovich, Jorge EduardoJuárez, Marta PatriciaCiencias MédicasTriatoma infestansBeauveria bassianaChagas diseaseCurrent Chagas disease vector control strategies, based on chemical insecticide spraying, are growingly threatened by the emergence of pyrethroid-resistant <i>Triatoma infestans</i> populations in the Gran Chaco region of South America. We have already shown that the entomopathogenic fungus <i>Beauveria bassiana</i> has the ability to breach the insect cuticle and is effective both against pyrethroid-susceptible and pyrethroid-resistant <i>T. infestans</i>, in laboratory as well as field assays. It is also known that <i>T. infestans</i> cuticle lipids play a major role as contact aggregation pheromones. We estimated the effectiveness of pheromone-based infection boxes containing <i>B. bassiana</i> spores to kill indoor bugs, and its effect on the vector population dynamics. Laboratory assays were performed to estimate the effect of fungal infection on female reproductive parameters. The effect of insect exuviae as an aggregation signal in the performance of the infection boxes was estimated both in the laboratory and in the field. We developed a stage-specific matrix model of <i>T. infestans</i> to describe the fungal infection effects on insect population dynamics, and to analyze the performance of the biopesticide device in vector biological control. The pheromone-containing infective box is a promising new tool against indoor populations of this Chagas disease vector, with the number of boxes per house being the main driver of the reduction of the total domestic bug population. This ecologically safe approach is the first proven alternative to chemical insecticides in the control of <i>T. infestans</i>. The advantageous reduction in vector population by delayed-action fungal biopesticides in a contained environment is here shown supported by mathematical modeling.Instituto de Investigaciones Bioquímicas de La PlataFacultad de Ciencias MédicasCentro de Estudios Parasitológicos y de Vectores2015info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://sedici.unlp.edu.ar/handle/10915/86190enginfo:eu-repo/semantics/altIdentifier/issn/1935-2727info:eu-repo/semantics/altIdentifier/doi/10.1371/journal.pntd.0003778info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/4.0/Creative Commons Attribution 4.0 International (CC BY 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-29T11:16:55Zoai:sedici.unlp.edu.ar:10915/86190Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-29 11:16:55.472SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv Biological Control of the Chagas Disease Vector <i>Triatoma infestans</i> with the Entomopathogenic Fungus <i>Beauveria bassiana</i> Combined with an Aggregation Cue: Field, Laboratory and Mathematical Modeling Assessment
title Biological Control of the Chagas Disease Vector <i>Triatoma infestans</i> with the Entomopathogenic Fungus <i>Beauveria bassiana</i> Combined with an Aggregation Cue: Field, Laboratory and Mathematical Modeling Assessment
spellingShingle Biological Control of the Chagas Disease Vector <i>Triatoma infestans</i> with the Entomopathogenic Fungus <i>Beauveria bassiana</i> Combined with an Aggregation Cue: Field, Laboratory and Mathematical Modeling Assessment
Forlani, Lucas
Ciencias Médicas
Triatoma infestans
Beauveria bassiana
Chagas disease
title_short Biological Control of the Chagas Disease Vector <i>Triatoma infestans</i> with the Entomopathogenic Fungus <i>Beauveria bassiana</i> Combined with an Aggregation Cue: Field, Laboratory and Mathematical Modeling Assessment
title_full Biological Control of the Chagas Disease Vector <i>Triatoma infestans</i> with the Entomopathogenic Fungus <i>Beauveria bassiana</i> Combined with an Aggregation Cue: Field, Laboratory and Mathematical Modeling Assessment
title_fullStr Biological Control of the Chagas Disease Vector <i>Triatoma infestans</i> with the Entomopathogenic Fungus <i>Beauveria bassiana</i> Combined with an Aggregation Cue: Field, Laboratory and Mathematical Modeling Assessment
title_full_unstemmed Biological Control of the Chagas Disease Vector <i>Triatoma infestans</i> with the Entomopathogenic Fungus <i>Beauveria bassiana</i> Combined with an Aggregation Cue: Field, Laboratory and Mathematical Modeling Assessment
title_sort Biological Control of the Chagas Disease Vector <i>Triatoma infestans</i> with the Entomopathogenic Fungus <i>Beauveria bassiana</i> Combined with an Aggregation Cue: Field, Laboratory and Mathematical Modeling Assessment
dc.creator.none.fl_str_mv Forlani, Lucas
Pedrini, Nicolás
Girotti, Juan Roberto
Mijailovsky, Sergio Javier
Cardozo, Rubén M.
Gentile, Alberto G.
Hernández Suárez, Carlos M.
Rabinovich, Jorge Eduardo
Juárez, Marta Patricia
author Forlani, Lucas
author_facet Forlani, Lucas
Pedrini, Nicolás
Girotti, Juan Roberto
Mijailovsky, Sergio Javier
Cardozo, Rubén M.
Gentile, Alberto G.
Hernández Suárez, Carlos M.
Rabinovich, Jorge Eduardo
Juárez, Marta Patricia
author_role author
author2 Pedrini, Nicolás
Girotti, Juan Roberto
Mijailovsky, Sergio Javier
Cardozo, Rubén M.
Gentile, Alberto G.
Hernández Suárez, Carlos M.
Rabinovich, Jorge Eduardo
Juárez, Marta Patricia
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Ciencias Médicas
Triatoma infestans
Beauveria bassiana
Chagas disease
topic Ciencias Médicas
Triatoma infestans
Beauveria bassiana
Chagas disease
dc.description.none.fl_txt_mv Current Chagas disease vector control strategies, based on chemical insecticide spraying, are growingly threatened by the emergence of pyrethroid-resistant <i>Triatoma infestans</i> populations in the Gran Chaco region of South America. We have already shown that the entomopathogenic fungus <i>Beauveria bassiana</i> has the ability to breach the insect cuticle and is effective both against pyrethroid-susceptible and pyrethroid-resistant <i>T. infestans</i>, in laboratory as well as field assays. It is also known that <i>T. infestans</i> cuticle lipids play a major role as contact aggregation pheromones. We estimated the effectiveness of pheromone-based infection boxes containing <i>B. bassiana</i> spores to kill indoor bugs, and its effect on the vector population dynamics. Laboratory assays were performed to estimate the effect of fungal infection on female reproductive parameters. The effect of insect exuviae as an aggregation signal in the performance of the infection boxes was estimated both in the laboratory and in the field. We developed a stage-specific matrix model of <i>T. infestans</i> to describe the fungal infection effects on insect population dynamics, and to analyze the performance of the biopesticide device in vector biological control. The pheromone-containing infective box is a promising new tool against indoor populations of this Chagas disease vector, with the number of boxes per house being the main driver of the reduction of the total domestic bug population. This ecologically safe approach is the first proven alternative to chemical insecticides in the control of <i>T. infestans</i>. The advantageous reduction in vector population by delayed-action fungal biopesticides in a contained environment is here shown supported by mathematical modeling.
Instituto de Investigaciones Bioquímicas de La Plata
Facultad de Ciencias Médicas
Centro de Estudios Parasitológicos y de Vectores
description Current Chagas disease vector control strategies, based on chemical insecticide spraying, are growingly threatened by the emergence of pyrethroid-resistant <i>Triatoma infestans</i> populations in the Gran Chaco region of South America. We have already shown that the entomopathogenic fungus <i>Beauveria bassiana</i> has the ability to breach the insect cuticle and is effective both against pyrethroid-susceptible and pyrethroid-resistant <i>T. infestans</i>, in laboratory as well as field assays. It is also known that <i>T. infestans</i> cuticle lipids play a major role as contact aggregation pheromones. We estimated the effectiveness of pheromone-based infection boxes containing <i>B. bassiana</i> spores to kill indoor bugs, and its effect on the vector population dynamics. Laboratory assays were performed to estimate the effect of fungal infection on female reproductive parameters. The effect of insect exuviae as an aggregation signal in the performance of the infection boxes was estimated both in the laboratory and in the field. We developed a stage-specific matrix model of <i>T. infestans</i> to describe the fungal infection effects on insect population dynamics, and to analyze the performance of the biopesticide device in vector biological control. The pheromone-containing infective box is a promising new tool against indoor populations of this Chagas disease vector, with the number of boxes per house being the main driver of the reduction of the total domestic bug population. This ecologically safe approach is the first proven alternative to chemical insecticides in the control of <i>T. infestans</i>. The advantageous reduction in vector population by delayed-action fungal biopesticides in a contained environment is here shown supported by mathematical modeling.
publishDate 2015
dc.date.none.fl_str_mv 2015
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Articulo
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info:ar-repo/semantics/articulo
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status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/86190
url http://sedici.unlp.edu.ar/handle/10915/86190
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/issn/1935-2727
info:eu-repo/semantics/altIdentifier/doi/10.1371/journal.pntd.0003778
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/4.0/
Creative Commons Attribution 4.0 International (CC BY 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
Creative Commons Attribution 4.0 International (CC BY 4.0)
dc.format.none.fl_str_mv application/pdf
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repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
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