A discriminatory study of a pharmacokinetic model for intramuscular gentamicin in sheep

Autores
Errecalde, Jorge Oscar; Mariño, Eduardo L.
Año de publicación
1990
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The resulting serum concentrations were measured in six ewes after intramuscular administration of 10 mg/kg of gentamicin. The model providing the best fit for the experimental data was determined both by linear regression analysis between the experimental and theoretical values and by means of the Minimum Akaike Information Criterion Estimation (MAICE) test. Linear regression analysis showed certain differences favouring the monocompartmental model although the advantage was not conclusive. The MAICE test, however, permitted a clear discrimination in favour of the same model. When linear regression analysis is not conclusive, the MAICE test represents a good alternative.
Facultad de Ciencias Veterinarias
Materia
Ciencias Veterinarias
Gentamicin
Models
Pharmacokinetics
Sheep
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/143250
Acceder
id SEDICI_56d72693eced71552ba552a88d34b161
oai_identifier_str oai:sedici.unlp.edu.ar:10915/143250
network_acronym_str SEDICI
repository_id_str 1329
network_name_str SEDICI (UNLP)
spelling A discriminatory study of a pharmacokinetic model for intramuscular gentamicin in sheepErrecalde, Jorge OscarMariño, Eduardo L.Ciencias VeterinariasGentamicinModelsPharmacokineticsSheepThe resulting serum concentrations were measured in six ewes after intramuscular administration of 10 mg/kg of gentamicin. The model providing the best fit for the experimental data was determined both by linear regression analysis between the experimental and theoretical values and by means of the Minimum Akaike Information Criterion Estimation (MAICE) test. Linear regression analysis showed certain differences favouring the monocompartmental model although the advantage was not conclusive. The MAICE test, however, permitted a clear discrimination in favour of the same model. When linear regression analysis is not conclusive, the MAICE test represents a good alternative.Facultad de Ciencias Veterinarias1990info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdf53-58http://sedici.unlp.edu.ar/handle/10915/143250enginfo:eu-repo/semantics/altIdentifier/issn/0165-7380info:eu-repo/semantics/altIdentifier/issn/1573-7446info:eu-repo/semantics/altIdentifier/doi/10.1007/bf00346384info:eu-repo/semantics/altIdentifier/pmid/2316193info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-03T11:04:18Zoai:sedici.unlp.edu.ar:10915/143250Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-03 11:04:18.458SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv A discriminatory study of a pharmacokinetic model for intramuscular gentamicin in sheep
title A discriminatory study of a pharmacokinetic model for intramuscular gentamicin in sheep
spellingShingle A discriminatory study of a pharmacokinetic model for intramuscular gentamicin in sheep
Errecalde, Jorge Oscar
Ciencias Veterinarias
Gentamicin
Models
Pharmacokinetics
Sheep
title_short A discriminatory study of a pharmacokinetic model for intramuscular gentamicin in sheep
title_full A discriminatory study of a pharmacokinetic model for intramuscular gentamicin in sheep
title_fullStr A discriminatory study of a pharmacokinetic model for intramuscular gentamicin in sheep
title_full_unstemmed A discriminatory study of a pharmacokinetic model for intramuscular gentamicin in sheep
title_sort A discriminatory study of a pharmacokinetic model for intramuscular gentamicin in sheep
dc.creator.none.fl_str_mv Errecalde, Jorge Oscar
Mariño, Eduardo L.
author Errecalde, Jorge Oscar
author_facet Errecalde, Jorge Oscar
Mariño, Eduardo L.
author_role author
author2 Mariño, Eduardo L.
author2_role author
dc.subject.none.fl_str_mv Ciencias Veterinarias
Gentamicin
Models
Pharmacokinetics
Sheep
topic Ciencias Veterinarias
Gentamicin
Models
Pharmacokinetics
Sheep
dc.description.none.fl_txt_mv The resulting serum concentrations were measured in six ewes after intramuscular administration of 10 mg/kg of gentamicin. The model providing the best fit for the experimental data was determined both by linear regression analysis between the experimental and theoretical values and by means of the Minimum Akaike Information Criterion Estimation (MAICE) test. Linear regression analysis showed certain differences favouring the monocompartmental model although the advantage was not conclusive. The MAICE test, however, permitted a clear discrimination in favour of the same model. When linear regression analysis is not conclusive, the MAICE test represents a good alternative.
Facultad de Ciencias Veterinarias
description The resulting serum concentrations were measured in six ewes after intramuscular administration of 10 mg/kg of gentamicin. The model providing the best fit for the experimental data was determined both by linear regression analysis between the experimental and theoretical values and by means of the Minimum Akaike Information Criterion Estimation (MAICE) test. Linear regression analysis showed certain differences favouring the monocompartmental model although the advantage was not conclusive. The MAICE test, however, permitted a clear discrimination in favour of the same model. When linear regression analysis is not conclusive, the MAICE test represents a good alternative.
publishDate 1990
dc.date.none.fl_str_mv 1990
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Articulo
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/143250
url http://sedici.unlp.edu.ar/handle/10915/143250
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/issn/0165-7380
info:eu-repo/semantics/altIdentifier/issn/1573-7446
info:eu-repo/semantics/altIdentifier/doi/10.1007/bf00346384
info:eu-repo/semantics/altIdentifier/pmid/2316193
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv application/pdf
53-58
dc.source.none.fl_str_mv reponame:SEDICI (UNLP)
instname:Universidad Nacional de La Plata
instacron:UNLP
reponame_str SEDICI (UNLP)
collection SEDICI (UNLP)
instname_str Universidad Nacional de La Plata
instacron_str UNLP
institution UNLP
repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
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score 13.13397

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