Assessing Urban Yellow Fever Transmission Risk: Aedes aegypti Vector Competence in Argentina

Autores
Boaglio, Estefanía R.; Muttis, Evangelina; Feroci, Mariel; Fabbri, Cintia; Minardi, Graciela; Sánchez, Juliana Patricia; Micieli, María Victoria; Goenaga, Silvina
Año de publicación
2025
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Yellow fever is a viral disease with historical importance since epidemics caused thousands of deaths at the end of the 19th century in Argentina. That event was associated with the presence of Aedes aegypti. After the mosquito eradication in South America in the 1960–1970 decade, no epidemic was detected related to this species but epizootics have occurred due to sylvatic vectors belonging to Haemagogus and Sabethes genera. Due to the recolonization of Ae. aegypti and its expanded distribution, the risk of the urbanization of yellow fever has increased over time. However, the reasons why the urban cycle of the yellow fever virus (YFV) has not occurred in South America so far are unknown. We explore the vector competence of Ae. aegypti for YFV transmission. The mosquitos evaluated belonged to colonies from center and northwest cities from Argentina, taking into account the particular genetic features of this mosquito species detected in this country from 2016. We used a viral strain originally isolated in 2009 from Sabethes albiprivus in the country. Viral infection in mosquito body, legs, and saliva was evaluated to estimate the rates of infection, dissemination, and transmission. Our results indicate that both mosquito colonies are competent vectors in the transmission of the YFV but with differences between them. Regarding the infection timeline, we observed a very early infection in the La Plata colony at 3 DPI in contrast to previous studies. This research improves our understanding of the risks of urban YFV transmission in Argentina, highlighting the need for surveillance and specialized vector control strategies in urban settings to prevent yellow fever outbreaks.
Centro de Estudios Parasitológicos y de Vectores
Materia
Biología
yellow fever virus
Argentina
Aedes aegypti
vector competence
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/181447
Acceder
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spelling Assessing Urban Yellow Fever Transmission Risk: Aedes aegypti Vector Competence in ArgentinaBoaglio, Estefanía R.Muttis, EvangelinaFeroci, MarielFabbri, CintiaMinardi, GracielaSánchez, Juliana PatriciaMicieli, María VictoriaGoenaga, SilvinaBiologíayellow fever virusArgentinaAedes aegyptivector competenceYellow fever is a viral disease with historical importance since epidemics caused thousands of deaths at the end of the 19th century in Argentina. That event was associated with the presence of Aedes aegypti. After the mosquito eradication in South America in the 1960–1970 decade, no epidemic was detected related to this species but epizootics have occurred due to sylvatic vectors belonging to Haemagogus and Sabethes genera. Due to the recolonization of Ae. aegypti and its expanded distribution, the risk of the urbanization of yellow fever has increased over time. However, the reasons why the urban cycle of the yellow fever virus (YFV) has not occurred in South America so far are unknown. We explore the vector competence of Ae. aegypti for YFV transmission. The mosquitos evaluated belonged to colonies from center and northwest cities from Argentina, taking into account the particular genetic features of this mosquito species detected in this country from 2016. We used a viral strain originally isolated in 2009 from Sabethes albiprivus in the country. Viral infection in mosquito body, legs, and saliva was evaluated to estimate the rates of infection, dissemination, and transmission. Our results indicate that both mosquito colonies are competent vectors in the transmission of the YFV but with differences between them. Regarding the infection timeline, we observed a very early infection in the La Plata colony at 3 DPI in contrast to previous studies. This research improves our understanding of the risks of urban YFV transmission in Argentina, highlighting the need for surveillance and specialized vector control strategies in urban settings to prevent yellow fever outbreaks.Centro de Estudios Parasitológicos y de Vectores2025-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://sedici.unlp.edu.ar/handle/10915/181447enginfo:eu-repo/semantics/altIdentifier/issn/1999-4915info:eu-repo/semantics/altIdentifier/doi/10.3390/v17050718info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/4.0/Creative Commons Attribution 4.0 International (CC BY 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-03T11:21:22Zoai:sedici.unlp.edu.ar:10915/181447Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-03 11:21:22.864SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv Assessing Urban Yellow Fever Transmission Risk: Aedes aegypti Vector Competence in Argentina
title Assessing Urban Yellow Fever Transmission Risk: Aedes aegypti Vector Competence in Argentina
spellingShingle Assessing Urban Yellow Fever Transmission Risk: Aedes aegypti Vector Competence in Argentina
Boaglio, Estefanía R.
Biología
yellow fever virus
Argentina
Aedes aegypti
vector competence
title_short Assessing Urban Yellow Fever Transmission Risk: Aedes aegypti Vector Competence in Argentina
title_full Assessing Urban Yellow Fever Transmission Risk: Aedes aegypti Vector Competence in Argentina
title_fullStr Assessing Urban Yellow Fever Transmission Risk: Aedes aegypti Vector Competence in Argentina
title_full_unstemmed Assessing Urban Yellow Fever Transmission Risk: Aedes aegypti Vector Competence in Argentina
title_sort Assessing Urban Yellow Fever Transmission Risk: Aedes aegypti Vector Competence in Argentina
dc.creator.none.fl_str_mv Boaglio, Estefanía R.
Muttis, Evangelina
Feroci, Mariel
Fabbri, Cintia
Minardi, Graciela
Sánchez, Juliana Patricia
Micieli, María Victoria
Goenaga, Silvina
author Boaglio, Estefanía R.
author_facet Boaglio, Estefanía R.
Muttis, Evangelina
Feroci, Mariel
Fabbri, Cintia
Minardi, Graciela
Sánchez, Juliana Patricia
Micieli, María Victoria
Goenaga, Silvina
author_role author
author2 Muttis, Evangelina
Feroci, Mariel
Fabbri, Cintia
Minardi, Graciela
Sánchez, Juliana Patricia
Micieli, María Victoria
Goenaga, Silvina
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Biología
yellow fever virus
Argentina
Aedes aegypti
vector competence
topic Biología
yellow fever virus
Argentina
Aedes aegypti
vector competence
dc.description.none.fl_txt_mv Yellow fever is a viral disease with historical importance since epidemics caused thousands of deaths at the end of the 19th century in Argentina. That event was associated with the presence of Aedes aegypti. After the mosquito eradication in South America in the 1960–1970 decade, no epidemic was detected related to this species but epizootics have occurred due to sylvatic vectors belonging to Haemagogus and Sabethes genera. Due to the recolonization of Ae. aegypti and its expanded distribution, the risk of the urbanization of yellow fever has increased over time. However, the reasons why the urban cycle of the yellow fever virus (YFV) has not occurred in South America so far are unknown. We explore the vector competence of Ae. aegypti for YFV transmission. The mosquitos evaluated belonged to colonies from center and northwest cities from Argentina, taking into account the particular genetic features of this mosquito species detected in this country from 2016. We used a viral strain originally isolated in 2009 from Sabethes albiprivus in the country. Viral infection in mosquito body, legs, and saliva was evaluated to estimate the rates of infection, dissemination, and transmission. Our results indicate that both mosquito colonies are competent vectors in the transmission of the YFV but with differences between them. Regarding the infection timeline, we observed a very early infection in the La Plata colony at 3 DPI in contrast to previous studies. This research improves our understanding of the risks of urban YFV transmission in Argentina, highlighting the need for surveillance and specialized vector control strategies in urban settings to prevent yellow fever outbreaks.
Centro de Estudios Parasitológicos y de Vectores
description Yellow fever is a viral disease with historical importance since epidemics caused thousands of deaths at the end of the 19th century in Argentina. That event was associated with the presence of Aedes aegypti. After the mosquito eradication in South America in the 1960–1970 decade, no epidemic was detected related to this species but epizootics have occurred due to sylvatic vectors belonging to Haemagogus and Sabethes genera. Due to the recolonization of Ae. aegypti and its expanded distribution, the risk of the urbanization of yellow fever has increased over time. However, the reasons why the urban cycle of the yellow fever virus (YFV) has not occurred in South America so far are unknown. We explore the vector competence of Ae. aegypti for YFV transmission. The mosquitos evaluated belonged to colonies from center and northwest cities from Argentina, taking into account the particular genetic features of this mosquito species detected in this country from 2016. We used a viral strain originally isolated in 2009 from Sabethes albiprivus in the country. Viral infection in mosquito body, legs, and saliva was evaluated to estimate the rates of infection, dissemination, and transmission. Our results indicate that both mosquito colonies are competent vectors in the transmission of the YFV but with differences between them. Regarding the infection timeline, we observed a very early infection in the La Plata colony at 3 DPI in contrast to previous studies. This research improves our understanding of the risks of urban YFV transmission in Argentina, highlighting the need for surveillance and specialized vector control strategies in urban settings to prevent yellow fever outbreaks.
publishDate 2025
dc.date.none.fl_str_mv 2025-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Articulo
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
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status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/181447
url http://sedici.unlp.edu.ar/handle/10915/181447
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/issn/1999-4915
info:eu-repo/semantics/altIdentifier/doi/10.3390/v17050718
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/4.0/
Creative Commons Attribution 4.0 International (CC BY 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
Creative Commons Attribution 4.0 International (CC BY 4.0)
dc.format.none.fl_str_mv application/pdf
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instname_str Universidad Nacional de La Plata
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institution UNLP
repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
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