Liver and heart mitochondria obtained from Adelie penguin (<i>Pygoscelis adeliae</i>) offers high resistance to lipid peroxidation

Autores
Gavazza, Mariana Beatriz; Marmunti, Monica Edith; Montalti, Diego; Gutiérrez, Ana María
Año de publicación
2008
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Lipid peroxidation is generally thought to be a major mechanism of cell injury in aerobic organisms subjected to oxidative stress. All cellular membranes are especially vulnerable to oxidation due to their high concentration of polyunsaturated fatty acids. However, birds have special adaptations for preventing membrane damage caused by reactive oxygen species. This study examines fatty acid profiles and susceptibility to lipid peroxidation in liver and heart mitochondria obtained from Adelie penguin (Pygoscelis adeliae). The saturated fatty acids in these organelles represent approximately 40–50% of total fatty acids whereas the polyunsaturated fatty acid composition was highly distinctive, characterized by almost equal amounts of 18:2 n-6; 20:4n-6 and 22:6 n-3 in liver mitochondria, and a higher proportion of 18:2 n-6 compared to 20:4n-6 and 22:6 n-3 in heart mitochondria. The concentration of total unsaturated fatty acids of liver and heart mitochondria was approximately 50% and 60%, respectively, with a prevalence of oleic acid C18:1 n9. The rate C20:4 n6 / C18:2 n6 and the unsaturation index was similar in liver and heart mitochondria; 104.33 ± 6.73 and 100.09 ± 3.07, respectively. Light emission originating from these organelles showed no statistically significant differences and the polyunsaturated fatty acid profiles did not change during the lipid peroxidation process.
Facultad de Ciencias Veterinarias
Facultad de Ciencias Naturales y Museo
Materia
Veterinaria
Ciencias Naturales
penguin
lipid peroxidation
liver
heart-mitochondria
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/131273

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spelling Liver and heart mitochondria obtained from Adelie penguin (<i>Pygoscelis adeliae</i>) offers high resistance to lipid peroxidationGavazza, Mariana BeatrizMarmunti, Monica EdithMontalti, DiegoGutiérrez, Ana MaríaVeterinariaCiencias Naturalespenguinlipid peroxidationliverheart-mitochondriaLipid peroxidation is generally thought to be a major mechanism of cell injury in aerobic organisms subjected to oxidative stress. All cellular membranes are especially vulnerable to oxidation due to their high concentration of polyunsaturated fatty acids. However, birds have special adaptations for preventing membrane damage caused by reactive oxygen species. This study examines fatty acid profiles and susceptibility to lipid peroxidation in liver and heart mitochondria obtained from Adelie penguin (<i>Pygoscelis adeliae</i>). The saturated fatty acids in these organelles represent approximately 40–50% of total fatty acids whereas the polyunsaturated fatty acid composition was highly distinctive, characterized by almost equal amounts of 18:2 n-6; 20:4n-6 and 22:6 n-3 in liver mitochondria, and a higher proportion of 18:2 n-6 compared to 20:4n-6 and 22:6 n-3 in heart mitochondria. The concentration of total unsaturated fatty acids of liver and heart mitochondria was approximately 50% and 60%, respectively, with a prevalence of oleic acid C18:1 n9. The rate C20:4 n6 / C18:2 n6 and the unsaturation index was similar in liver and heart mitochondria; 104.33 ± 6.73 and 100.09 ± 3.07, respectively. Light emission originating from these organelles showed no statistically significant differences and the polyunsaturated fatty acid profiles did not change during the lipid peroxidation process.Facultad de Ciencias VeterinariasFacultad de Ciencias Naturales y Museo2008info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdf185-194http://sedici.unlp.edu.ar/handle/10915/131273enginfo:eu-repo/semantics/altIdentifier/issn/0236-5383info:eu-repo/semantics/altIdentifier/issn/1588-256Xinfo:eu-repo/semantics/altIdentifier/doi/10.1556/abiol.59.2008.2.5info:eu-repo/semantics/altIdentifier/pmid/18637558info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-29T11:32:26Zoai:sedici.unlp.edu.ar:10915/131273Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-29 11:32:27.233SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv Liver and heart mitochondria obtained from Adelie penguin (<i>Pygoscelis adeliae</i>) offers high resistance to lipid peroxidation
title Liver and heart mitochondria obtained from Adelie penguin (<i>Pygoscelis adeliae</i>) offers high resistance to lipid peroxidation
spellingShingle Liver and heart mitochondria obtained from Adelie penguin (<i>Pygoscelis adeliae</i>) offers high resistance to lipid peroxidation
Gavazza, Mariana Beatriz
Veterinaria
Ciencias Naturales
penguin
lipid peroxidation
liver
heart-mitochondria
title_short Liver and heart mitochondria obtained from Adelie penguin (<i>Pygoscelis adeliae</i>) offers high resistance to lipid peroxidation
title_full Liver and heart mitochondria obtained from Adelie penguin (<i>Pygoscelis adeliae</i>) offers high resistance to lipid peroxidation
title_fullStr Liver and heart mitochondria obtained from Adelie penguin (<i>Pygoscelis adeliae</i>) offers high resistance to lipid peroxidation
title_full_unstemmed Liver and heart mitochondria obtained from Adelie penguin (<i>Pygoscelis adeliae</i>) offers high resistance to lipid peroxidation
title_sort Liver and heart mitochondria obtained from Adelie penguin (<i>Pygoscelis adeliae</i>) offers high resistance to lipid peroxidation
dc.creator.none.fl_str_mv Gavazza, Mariana Beatriz
Marmunti, Monica Edith
Montalti, Diego
Gutiérrez, Ana María
author Gavazza, Mariana Beatriz
author_facet Gavazza, Mariana Beatriz
Marmunti, Monica Edith
Montalti, Diego
Gutiérrez, Ana María
author_role author
author2 Marmunti, Monica Edith
Montalti, Diego
Gutiérrez, Ana María
author2_role author
author
author
dc.subject.none.fl_str_mv Veterinaria
Ciencias Naturales
penguin
lipid peroxidation
liver
heart-mitochondria
topic Veterinaria
Ciencias Naturales
penguin
lipid peroxidation
liver
heart-mitochondria
dc.description.none.fl_txt_mv Lipid peroxidation is generally thought to be a major mechanism of cell injury in aerobic organisms subjected to oxidative stress. All cellular membranes are especially vulnerable to oxidation due to their high concentration of polyunsaturated fatty acids. However, birds have special adaptations for preventing membrane damage caused by reactive oxygen species. This study examines fatty acid profiles and susceptibility to lipid peroxidation in liver and heart mitochondria obtained from Adelie penguin (<i>Pygoscelis adeliae</i>). The saturated fatty acids in these organelles represent approximately 40–50% of total fatty acids whereas the polyunsaturated fatty acid composition was highly distinctive, characterized by almost equal amounts of 18:2 n-6; 20:4n-6 and 22:6 n-3 in liver mitochondria, and a higher proportion of 18:2 n-6 compared to 20:4n-6 and 22:6 n-3 in heart mitochondria. The concentration of total unsaturated fatty acids of liver and heart mitochondria was approximately 50% and 60%, respectively, with a prevalence of oleic acid C18:1 n9. The rate C20:4 n6 / C18:2 n6 and the unsaturation index was similar in liver and heart mitochondria; 104.33 ± 6.73 and 100.09 ± 3.07, respectively. Light emission originating from these organelles showed no statistically significant differences and the polyunsaturated fatty acid profiles did not change during the lipid peroxidation process.
Facultad de Ciencias Veterinarias
Facultad de Ciencias Naturales y Museo
description Lipid peroxidation is generally thought to be a major mechanism of cell injury in aerobic organisms subjected to oxidative stress. All cellular membranes are especially vulnerable to oxidation due to their high concentration of polyunsaturated fatty acids. However, birds have special adaptations for preventing membrane damage caused by reactive oxygen species. This study examines fatty acid profiles and susceptibility to lipid peroxidation in liver and heart mitochondria obtained from Adelie penguin (<i>Pygoscelis adeliae</i>). The saturated fatty acids in these organelles represent approximately 40–50% of total fatty acids whereas the polyunsaturated fatty acid composition was highly distinctive, characterized by almost equal amounts of 18:2 n-6; 20:4n-6 and 22:6 n-3 in liver mitochondria, and a higher proportion of 18:2 n-6 compared to 20:4n-6 and 22:6 n-3 in heart mitochondria. The concentration of total unsaturated fatty acids of liver and heart mitochondria was approximately 50% and 60%, respectively, with a prevalence of oleic acid C18:1 n9. The rate C20:4 n6 / C18:2 n6 and the unsaturation index was similar in liver and heart mitochondria; 104.33 ± 6.73 and 100.09 ± 3.07, respectively. Light emission originating from these organelles showed no statistically significant differences and the polyunsaturated fatty acid profiles did not change during the lipid peroxidation process.
publishDate 2008
dc.date.none.fl_str_mv 2008
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Articulo
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/131273
url http://sedici.unlp.edu.ar/handle/10915/131273
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/issn/0236-5383
info:eu-repo/semantics/altIdentifier/issn/1588-256X
info:eu-repo/semantics/altIdentifier/doi/10.1556/abiol.59.2008.2.5
info:eu-repo/semantics/altIdentifier/pmid/18637558
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv application/pdf
185-194
dc.source.none.fl_str_mv reponame:SEDICI (UNLP)
instname:Universidad Nacional de La Plata
instacron:UNLP
reponame_str SEDICI (UNLP)
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institution UNLP
repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
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