Host–guest supramolecular chemistry in solid-state nanopores: potassium-driven modulation of ionic transport in nanofluidic diodes

Autores
Pérez Mitta, Gonzalo; Albesa, Alberto Gustavo; Knoll, Wolfgang; Trautmann, Christina; Toimil-Molares, María Eugenia; Azzaroni, Omar
Año de publicación
2015
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
We describe the use of asymmetric nanopores decorated with crown ethers for constructing robust signal-responsive chemical devices. The modification of single conical nanopores with 18-crown-6 units led to a nanodevice whose electronic readout, derived from the transmembrane ion current, can be finely tuned over a wide range of K⁺ concentrations. The electrostatic characteristics of the nanopore environment arising from host–guest ion-recognition processes taking place on the pore walls are responsible for tuning the transmembrane ionic transport and the rectification properties of the pore. This work illustrates the potential and versatility of host–guest chemistry, in combination with nanofluidic elements, as a key enabler to achieve addressable chemical nanodevices mimicking the ion transport properties and gating functions of specific biological channels.
Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas
Materia
Ciencias Exactas
Química
asymmetric nanopores
chemical nanodevices
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/147625
Acceder
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oai_identifier_str oai:sedici.unlp.edu.ar:10915/147625
network_acronym_str SEDICI
repository_id_str 1329
network_name_str SEDICI (UNLP)
spelling Host–guest supramolecular chemistry in solid-state nanopores: potassium-driven modulation of ionic transport in nanofluidic diodesPérez Mitta, GonzaloAlbesa, Alberto GustavoKnoll, WolfgangTrautmann, ChristinaToimil-Molares, María EugeniaAzzaroni, OmarCiencias ExactasQuímicaasymmetric nanoporeschemical nanodevicesWe describe the use of asymmetric nanopores decorated with crown ethers for constructing robust signal-responsive chemical devices. The modification of single conical nanopores with 18-crown-6 units led to a nanodevice whose electronic readout, derived from the transmembrane ion current, can be finely tuned over a wide range of K⁺ concentrations. The electrostatic characteristics of the nanopore environment arising from host–guest ion-recognition processes taking place on the pore walls are responsible for tuning the transmembrane ionic transport and the rectification properties of the pore. This work illustrates the potential and versatility of host–guest chemistry, in combination with nanofluidic elements, as a key enabler to achieve addressable chemical nanodevices mimicking the ion transport properties and gating functions of specific biological channels.Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas2015info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdf15594-15598http://sedici.unlp.edu.ar/handle/10915/147625enginfo:eu-repo/semantics/altIdentifier/issn/2040-3364info:eu-repo/semantics/altIdentifier/issn/2040-3372info:eu-repo/semantics/altIdentifier/doi/10.1039/c5nr04645ainfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/4.0/Creative Commons Attribution 4.0 International (CC BY 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2025-09-03T11:09:45Zoai:sedici.unlp.edu.ar:10915/147625Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292025-09-03 11:09:45.586SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv Host–guest supramolecular chemistry in solid-state nanopores: potassium-driven modulation of ionic transport in nanofluidic diodes
title Host–guest supramolecular chemistry in solid-state nanopores: potassium-driven modulation of ionic transport in nanofluidic diodes
spellingShingle Host–guest supramolecular chemistry in solid-state nanopores: potassium-driven modulation of ionic transport in nanofluidic diodes
Pérez Mitta, Gonzalo
Ciencias Exactas
Química
asymmetric nanopores
chemical nanodevices
title_short Host–guest supramolecular chemistry in solid-state nanopores: potassium-driven modulation of ionic transport in nanofluidic diodes
title_full Host–guest supramolecular chemistry in solid-state nanopores: potassium-driven modulation of ionic transport in nanofluidic diodes
title_fullStr Host–guest supramolecular chemistry in solid-state nanopores: potassium-driven modulation of ionic transport in nanofluidic diodes
title_full_unstemmed Host–guest supramolecular chemistry in solid-state nanopores: potassium-driven modulation of ionic transport in nanofluidic diodes
title_sort Host–guest supramolecular chemistry in solid-state nanopores: potassium-driven modulation of ionic transport in nanofluidic diodes
dc.creator.none.fl_str_mv Pérez Mitta, Gonzalo
Albesa, Alberto Gustavo
Knoll, Wolfgang
Trautmann, Christina
Toimil-Molares, María Eugenia
Azzaroni, Omar
author Pérez Mitta, Gonzalo
author_facet Pérez Mitta, Gonzalo
Albesa, Alberto Gustavo
Knoll, Wolfgang
Trautmann, Christina
Toimil-Molares, María Eugenia
Azzaroni, Omar
author_role author
author2 Albesa, Alberto Gustavo
Knoll, Wolfgang
Trautmann, Christina
Toimil-Molares, María Eugenia
Azzaroni, Omar
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Ciencias Exactas
Química
asymmetric nanopores
chemical nanodevices
topic Ciencias Exactas
Química
asymmetric nanopores
chemical nanodevices
dc.description.none.fl_txt_mv We describe the use of asymmetric nanopores decorated with crown ethers for constructing robust signal-responsive chemical devices. The modification of single conical nanopores with 18-crown-6 units led to a nanodevice whose electronic readout, derived from the transmembrane ion current, can be finely tuned over a wide range of K⁺ concentrations. The electrostatic characteristics of the nanopore environment arising from host–guest ion-recognition processes taking place on the pore walls are responsible for tuning the transmembrane ionic transport and the rectification properties of the pore. This work illustrates the potential and versatility of host–guest chemistry, in combination with nanofluidic elements, as a key enabler to achieve addressable chemical nanodevices mimicking the ion transport properties and gating functions of specific biological channels.
Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas
description We describe the use of asymmetric nanopores decorated with crown ethers for constructing robust signal-responsive chemical devices. The modification of single conical nanopores with 18-crown-6 units led to a nanodevice whose electronic readout, derived from the transmembrane ion current, can be finely tuned over a wide range of K⁺ concentrations. The electrostatic characteristics of the nanopore environment arising from host–guest ion-recognition processes taking place on the pore walls are responsible for tuning the transmembrane ionic transport and the rectification properties of the pore. This work illustrates the potential and versatility of host–guest chemistry, in combination with nanofluidic elements, as a key enabler to achieve addressable chemical nanodevices mimicking the ion transport properties and gating functions of specific biological channels.
publishDate 2015
dc.date.none.fl_str_mv 2015
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Articulo
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/147625
url http://sedici.unlp.edu.ar/handle/10915/147625
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/issn/2040-3364
info:eu-repo/semantics/altIdentifier/issn/2040-3372
info:eu-repo/semantics/altIdentifier/doi/10.1039/c5nr04645a
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/4.0/
Creative Commons Attribution 4.0 International (CC BY 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
Creative Commons Attribution 4.0 International (CC BY 4.0)
dc.format.none.fl_str_mv application/pdf
15594-15598
dc.source.none.fl_str_mv reponame:SEDICI (UNLP)
instname:Universidad Nacional de La Plata
instacron:UNLP
reponame_str SEDICI (UNLP)
collection SEDICI (UNLP)
instname_str Universidad Nacional de La Plata
instacron_str UNLP
institution UNLP
repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
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score 13.13397

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