Identification of novel chemical scaffolds Inhibiting trypanothione synthetase from pathogenic trypanosomatids

Autores
Benítez, Diego; Medeiros, Andrea; Fiestas, Lucía; Panozzo Zénere, Esteban Andrés; Maiwald, Franziska; Prousis, Kyriakos C.; Roussaki, Marina; Calogeropoulou, Theodora; Detsi, Anastasia; Jaeger, Timo; Šarlauskas, Jonas; Peterlin Mašič, Lucíja; Kunick, Conrad; Labadie, Guillermo Roberto; Flohé, Leopold; Comini, Marcelo A.
Año de publicación
2016
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Fil: Fil: Benítez, Diego. Institut Pasteur de Montevideo. Laboratorio de Biologia Redox de Tripanosomátidos; Uruguay.
Fil: Fil: Medeiros, Andrea. Institut Pasteur de Montevideo. Laboratorio de Biología Redox de Tripanosomátidos; Uruguay.
Fil: Fil: Medeiros, Andrea. Universidad de la República. Departamento de Bioquímica; Uruguay.
Fil: Fil: Fiestas, Lucía. Institut Pasteur de Montevideo. Laboratorio de Biologia Redox de Tripanosomátidos; Uruguay.
Fil: Fil: Panozzo Zénere, Esteban Andrés. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario (IQUIR-CONICET); Argentina
Fil: Fil: Maiwald, Franziska. Technische Universität Braunschweig. Institut für Medizinische und Pharmazeutische Chemie; Deutschland.
Fil: Fil: Prousis, Kyriakos C. National Hellenic Research Foundation. Institute of Biology, Medicinal Chemistry and Biotechnology; Greece.
Fil: Fil: Roussaki, Marina. National Technical University of Athens. School of Chemical Engineering. Laboratory of Organic Chemistry; Greece.
Fil: Fil: Calogeropoulou, Theodora. National Hellenic Research Foundation. Institute of Biology, Medicinal Chemistry and Biotechnology; Greece.
Fil: Fil: Detsi, Anastasia. National Technical University of Athens. School of Chemical Engineering. Laboratory of Organic Chemistry; Greece.
Fil: Fil: Jaeger, Timo. German Centre for Infection Research, Braunschweig; Germany.
Fil: Fil: Šarlauskas, Jonas. Vilnius University. Department of the Biochemistry of Xenobiotics Institute of Biochemistry; Lithuania.
Fil: Fil: Peterlin Mašič, Lucíja. University of Ljubljana. Faculty of Pharmacy. Department for Medicinal Chemistry; Slovenia.
Fil: Fil: Kunick, Conrad. Technische Universität Braunschweig. Institut für Medizinische und Pharmazeutische Chemie; Deutschland.
Fil: Fil: Labadie, Guillermo Roberto. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario (IQUIR -CONICET); Argentina.
Fil: Fil: Flohé, Leopold. Universidad de la República. Departamento de Bioquímica; Uruguay.
Fil: Fil: Flohé, Leopold. Università degli Studi di Padova. Department of Molecular Medicine; Italy.
Fil: Fil: Comini, Marcelo A. Institut Pasteur de Montevideo. Laboratorio de Biologia Redox de Tripanosomátidos; Uruguay.
Materia
Neglected Diseases
Trypanothione Synthetase Inhibitors
Pathogenic Trypanosomatids
Leishmania
Trypanosoma
Nivel de accesibilidad
acceso abierto
Condiciones de uso
Attribution 4.0 International (CC BY 4.0)
Repositorio
RepHipUNR (UNR)
Institución
Universidad Nacional de Rosario
OAI Identificador
oai:rephip.unr.edu.ar:2133/19536
Acceder
id RepHipUNR_a2dcdcf8c8dfe95568cf440e54c4987e
oai_identifier_str oai:rephip.unr.edu.ar:2133/19536
network_acronym_str RepHipUNR
repository_id_str 1550
network_name_str RepHipUNR (UNR)
spelling Identification of novel chemical scaffolds Inhibiting trypanothione synthetase from pathogenic trypanosomatidsBenítez, DiegoMedeiros, AndreaFiestas, LucíaPanozzo Zénere, Esteban AndrésMaiwald, FranziskaProusis, Kyriakos C.Roussaki, MarinaCalogeropoulou, TheodoraDetsi, AnastasiaJaeger, TimoŠarlauskas, JonasPeterlin Mašič, LucíjaKunick, ConradLabadie, Guillermo RobertoFlohé, LeopoldComini, Marcelo A.Neglected DiseasesTrypanothione Synthetase InhibitorsPathogenic TrypanosomatidsLeishmaniaTrypanosomaFil: Fil: Benítez, Diego. Institut Pasteur de Montevideo. Laboratorio de Biologia Redox de Tripanosomátidos; Uruguay.Fil: Fil: Medeiros, Andrea. Institut Pasteur de Montevideo. Laboratorio de Biología Redox de Tripanosomátidos; Uruguay.Fil: Fil: Medeiros, Andrea. Universidad de la República. Departamento de Bioquímica; Uruguay.Fil: Fil: Fiestas, Lucía. Institut Pasteur de Montevideo. Laboratorio de Biologia Redox de Tripanosomátidos; Uruguay.Fil: Fil: Panozzo Zénere, Esteban Andrés. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario (IQUIR-CONICET); ArgentinaFil: Fil: Maiwald, Franziska. Technische Universität Braunschweig. Institut für Medizinische und Pharmazeutische Chemie; Deutschland.Fil: Fil: Prousis, Kyriakos C. National Hellenic Research Foundation. Institute of Biology, Medicinal Chemistry and Biotechnology; Greece.Fil: Fil: Roussaki, Marina. National Technical University of Athens. School of Chemical Engineering. Laboratory of Organic Chemistry; Greece.Fil: Fil: Calogeropoulou, Theodora. National Hellenic Research Foundation. Institute of Biology, Medicinal Chemistry and Biotechnology; Greece.Fil: Fil: Detsi, Anastasia. National Technical University of Athens. School of Chemical Engineering. Laboratory of Organic Chemistry; Greece.Fil: Fil: Jaeger, Timo. German Centre for Infection Research, Braunschweig; Germany.Fil: Fil: Šarlauskas, Jonas. Vilnius University. Department of the Biochemistry of Xenobiotics Institute of Biochemistry; Lithuania.Fil: Fil: Peterlin Mašič, Lucíja. University of Ljubljana. Faculty of Pharmacy. Department for Medicinal Chemistry; Slovenia.Fil: Fil: Kunick, Conrad. Technische Universität Braunschweig. Institut für Medizinische und Pharmazeutische Chemie; Deutschland.Fil: Fil: Labadie, Guillermo Roberto. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario (IQUIR -CONICET); Argentina.Fil: Fil: Flohé, Leopold. Universidad de la República. Departamento de Bioquímica; Uruguay.Fil: Fil: Flohé, Leopold. Università degli Studi di Padova. Department of Molecular Medicine; Italy.Fil: Fil: Comini, Marcelo A. Institut Pasteur de Montevideo. Laboratorio de Biologia Redox de Tripanosomátidos; Uruguay.Public Library of Science (PLOS)2016-04-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://hdl.handle.net/2133/19536urn:issn: 1935-2735enghttps://doi.org/10.1371/journal.pntd.0004617https://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0004617info:eu-repo/semantics/openAccessAttribution 4.0 International (CC BY 4.0)https://creativecommons.org/licenses/by/4.0/Licencia RepHipreponame:RepHipUNR (UNR)instname:Universidad Nacional de Rosario2025-10-16T09:27:45Zoai:rephip.unr.edu.ar:2133/19536instacron:UNRInstitucionalhttps://rephip.unr.edu.ar/Universidad públicaNo correspondehttps://rephip.unr.edu.ar/oai/requestrephip@unr.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:15502025-10-16 09:27:45.758RepHipUNR (UNR) - Universidad Nacional de Rosariofalse
dc.title.none.fl_str_mv Identification of novel chemical scaffolds Inhibiting trypanothione synthetase from pathogenic trypanosomatids
title Identification of novel chemical scaffolds Inhibiting trypanothione synthetase from pathogenic trypanosomatids
spellingShingle Identification of novel chemical scaffolds Inhibiting trypanothione synthetase from pathogenic trypanosomatids
Benítez, Diego
Neglected Diseases
Trypanothione Synthetase Inhibitors
Pathogenic Trypanosomatids
Leishmania
Trypanosoma
title_short Identification of novel chemical scaffolds Inhibiting trypanothione synthetase from pathogenic trypanosomatids
title_full Identification of novel chemical scaffolds Inhibiting trypanothione synthetase from pathogenic trypanosomatids
title_fullStr Identification of novel chemical scaffolds Inhibiting trypanothione synthetase from pathogenic trypanosomatids
title_full_unstemmed Identification of novel chemical scaffolds Inhibiting trypanothione synthetase from pathogenic trypanosomatids
title_sort Identification of novel chemical scaffolds Inhibiting trypanothione synthetase from pathogenic trypanosomatids
dc.creator.none.fl_str_mv Benítez, Diego
Medeiros, Andrea
Fiestas, Lucía
Panozzo Zénere, Esteban Andrés
Maiwald, Franziska
Prousis, Kyriakos C.
Roussaki, Marina
Calogeropoulou, Theodora
Detsi, Anastasia
Jaeger, Timo
Šarlauskas, Jonas
Peterlin Mašič, Lucíja
Kunick, Conrad
Labadie, Guillermo Roberto
Flohé, Leopold
Comini, Marcelo A.
author Benítez, Diego
author_facet Benítez, Diego
Medeiros, Andrea
Fiestas, Lucía
Panozzo Zénere, Esteban Andrés
Maiwald, Franziska
Prousis, Kyriakos C.
Roussaki, Marina
Calogeropoulou, Theodora
Detsi, Anastasia
Jaeger, Timo
Šarlauskas, Jonas
Peterlin Mašič, Lucíja
Kunick, Conrad
Labadie, Guillermo Roberto
Flohé, Leopold
Comini, Marcelo A.
author_role author
author2 Medeiros, Andrea
Fiestas, Lucía
Panozzo Zénere, Esteban Andrés
Maiwald, Franziska
Prousis, Kyriakos C.
Roussaki, Marina
Calogeropoulou, Theodora
Detsi, Anastasia
Jaeger, Timo
Šarlauskas, Jonas
Peterlin Mašič, Lucíja
Kunick, Conrad
Labadie, Guillermo Roberto
Flohé, Leopold
Comini, Marcelo A.
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Neglected Diseases
Trypanothione Synthetase Inhibitors
Pathogenic Trypanosomatids
Leishmania
Trypanosoma
topic Neglected Diseases
Trypanothione Synthetase Inhibitors
Pathogenic Trypanosomatids
Leishmania
Trypanosoma
dc.description.none.fl_txt_mv Fil: Fil: Benítez, Diego. Institut Pasteur de Montevideo. Laboratorio de Biologia Redox de Tripanosomátidos; Uruguay.
Fil: Fil: Medeiros, Andrea. Institut Pasteur de Montevideo. Laboratorio de Biología Redox de Tripanosomátidos; Uruguay.
Fil: Fil: Medeiros, Andrea. Universidad de la República. Departamento de Bioquímica; Uruguay.
Fil: Fil: Fiestas, Lucía. Institut Pasteur de Montevideo. Laboratorio de Biologia Redox de Tripanosomátidos; Uruguay.
Fil: Fil: Panozzo Zénere, Esteban Andrés. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario (IQUIR-CONICET); Argentina
Fil: Fil: Maiwald, Franziska. Technische Universität Braunschweig. Institut für Medizinische und Pharmazeutische Chemie; Deutschland.
Fil: Fil: Prousis, Kyriakos C. National Hellenic Research Foundation. Institute of Biology, Medicinal Chemistry and Biotechnology; Greece.
Fil: Fil: Roussaki, Marina. National Technical University of Athens. School of Chemical Engineering. Laboratory of Organic Chemistry; Greece.
Fil: Fil: Calogeropoulou, Theodora. National Hellenic Research Foundation. Institute of Biology, Medicinal Chemistry and Biotechnology; Greece.
Fil: Fil: Detsi, Anastasia. National Technical University of Athens. School of Chemical Engineering. Laboratory of Organic Chemistry; Greece.
Fil: Fil: Jaeger, Timo. German Centre for Infection Research, Braunschweig; Germany.
Fil: Fil: Šarlauskas, Jonas. Vilnius University. Department of the Biochemistry of Xenobiotics Institute of Biochemistry; Lithuania.
Fil: Fil: Peterlin Mašič, Lucíja. University of Ljubljana. Faculty of Pharmacy. Department for Medicinal Chemistry; Slovenia.
Fil: Fil: Kunick, Conrad. Technische Universität Braunschweig. Institut für Medizinische und Pharmazeutische Chemie; Deutschland.
Fil: Fil: Labadie, Guillermo Roberto. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario (IQUIR -CONICET); Argentina.
Fil: Fil: Flohé, Leopold. Universidad de la República. Departamento de Bioquímica; Uruguay.
Fil: Fil: Flohé, Leopold. Università degli Studi di Padova. Department of Molecular Medicine; Italy.
Fil: Fil: Comini, Marcelo A. Institut Pasteur de Montevideo. Laboratorio de Biologia Redox de Tripanosomátidos; Uruguay.
description Fil: Fil: Benítez, Diego. Institut Pasteur de Montevideo. Laboratorio de Biologia Redox de Tripanosomátidos; Uruguay.
publishDate 2016
dc.date.none.fl_str_mv 2016-04-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article


info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/2133/19536
urn:issn: 1935-2735
url http://hdl.handle.net/2133/19536
identifier_str_mv urn:issn: 1935-2735
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://doi.org/10.1371/journal.pntd.0004617
https://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0004617
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
Attribution 4.0 International (CC BY 4.0)
https://creativecommons.org/licenses/by/4.0/
Licencia RepHip
eu_rights_str_mv openAccess
rights_invalid_str_mv Attribution 4.0 International (CC BY 4.0)
https://creativecommons.org/licenses/by/4.0/
Licencia RepHip
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Public Library of Science (PLOS)
publisher.none.fl_str_mv Public Library of Science (PLOS)
dc.source.none.fl_str_mv reponame:RepHipUNR (UNR)
instname:Universidad Nacional de Rosario
reponame_str RepHipUNR (UNR)
collection RepHipUNR (UNR)
instname_str Universidad Nacional de Rosario
repository.name.fl_str_mv RepHipUNR (UNR) - Universidad Nacional de Rosario
repository.mail.fl_str_mv rephip@unr.edu.ar
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