Recent applications of superresolution microscopy in neurobiology

Autores
Willig, Katrin I.; Barrantes, Francisco José
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Fil: Willig, Katrin I. Center for Nanoscale Microscopy and Molecular Physiology of the Brain; Alemania
Fil: Willig, Katrin I. Max Planck Institute for Biophysical Chemistry. Department of NanoBiophotonics; Alemania
Fil: Barrantes, Francisco José. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas. Laboratorio de Neurobiología Molecular; Argentina
Fil: Barrantes, Francisco José. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Abstract: Chemical synapses in brain are structural differentiations where excitatory or inhibitory signals are vectorially transmitted between two neurons. Excitatory synapses occur mostly on dendritic spines, submicron sized protrusions of the neuronal dendritic arborizations. Axons establish contacts with these tiny specializations purported to be the smallest functional processing units in the central nervous system. The minute size of synapses and their macromolecular constituents creates an inherent difficulty for imaging but makes them an ideal object for superresolution microscopy. Here we discuss some representative examples of nanoscopy studies, ranging from quantification of receptors and scaffolding proteins in postsynaptic densities and their dynamic behavior, to imaging of synaptic vesicle proteins and dendritic spines in living neurons or even live animals.
Fuente
Current Opinion in Chemical Biology. 2014. 20
Materia
CEREBRO
NEUROBIOLOGIA
PROTEINAS
SINAPSIS
MICROSCOPIA
Nivel de accesibilidad
acceso embargado
Condiciones de uso
Repositorio
Repositorio Institucional (UCA)
Institución
Pontificia Universidad Católica Argentina
OAI Identificador
oai:ucacris:123456789/15338
Acceder
id RIUCA_3ddc1b8f176130797140bea0e336b67e
oai_identifier_str oai:ucacris:123456789/15338
network_acronym_str RIUCA
repository_id_str 2585
network_name_str Repositorio Institucional (UCA)
spelling Recent applications of superresolution microscopy in neurobiologyWillig, Katrin I.Barrantes, Francisco JoséCEREBRONEUROBIOLOGIAPROTEINASSINAPSISMICROSCOPIAFil: Willig, Katrin I. Center for Nanoscale Microscopy and Molecular Physiology of the Brain; AlemaniaFil: Willig, Katrin I. Max Planck Institute for Biophysical Chemistry. Department of NanoBiophotonics; AlemaniaFil: Barrantes, Francisco José. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas. Laboratorio de Neurobiología Molecular; ArgentinaFil: Barrantes, Francisco José. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaAbstract: Chemical synapses in brain are structural differentiations where excitatory or inhibitory signals are vectorially transmitted between two neurons. Excitatory synapses occur mostly on dendritic spines, submicron sized protrusions of the neuronal dendritic arborizations. Axons establish contacts with these tiny specializations purported to be the smallest functional processing units in the central nervous system. The minute size of synapses and their macromolecular constituents creates an inherent difficulty for imaging but makes them an ideal object for superresolution microscopy. Here we discuss some representative examples of nanoscopy studies, ranging from quantification of receptors and scaffolding proteins in postsynaptic densities and their dynamic behavior, to imaging of synaptic vesicle proteins and dendritic spines in living neurons or even live animals.Elsevierinfo:eu-repo/date/embargoEnd/2100-01-012014info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttps://repositorio.uca.edu.ar/handle/123456789/153381367-593110.1016/j.cbpa.2014.03.02124793373Willig, K.I., Barrantes, F.J. Recent applications of superresolution microscopy in neurobiology [en línea]. Current Opinion in Chemical Biology. 2014. 20 doi:10.1016/j.cbpa.2014.03.021 Disponible en: https://repositorio.uca.edu.ar/handle/123456789/15338Current Opinion in Chemical Biology. 2014. 20reponame:Repositorio Institucional (UCA)instname:Pontificia Universidad Católica Argentinaenginfo:eu-repo/semantics/embargoedAccess2025-07-03T10:58:55Zoai:ucacris:123456789/15338instacron:UCAInstitucionalhttps://repositorio.uca.edu.ar/Universidad privadaNo correspondehttps://repositorio.uca.edu.ar/oaiclaudia_fernandez@uca.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:25852025-07-03 10:58:55.94Repositorio Institucional (UCA) - Pontificia Universidad Católica Argentinafalse
dc.title.none.fl_str_mv Recent applications of superresolution microscopy in neurobiology
title Recent applications of superresolution microscopy in neurobiology
spellingShingle Recent applications of superresolution microscopy in neurobiology
Willig, Katrin I.
CEREBRO
NEUROBIOLOGIA
PROTEINAS
SINAPSIS
MICROSCOPIA
title_short Recent applications of superresolution microscopy in neurobiology
title_full Recent applications of superresolution microscopy in neurobiology
title_fullStr Recent applications of superresolution microscopy in neurobiology
title_full_unstemmed Recent applications of superresolution microscopy in neurobiology
title_sort Recent applications of superresolution microscopy in neurobiology
dc.creator.none.fl_str_mv Willig, Katrin I.
Barrantes, Francisco José
author Willig, Katrin I.
author_facet Willig, Katrin I.
Barrantes, Francisco José
author_role author
author2 Barrantes, Francisco José
author2_role author
dc.subject.none.fl_str_mv CEREBRO
NEUROBIOLOGIA
PROTEINAS
SINAPSIS
MICROSCOPIA
topic CEREBRO
NEUROBIOLOGIA
PROTEINAS
SINAPSIS
MICROSCOPIA
dc.description.none.fl_txt_mv Fil: Willig, Katrin I. Center for Nanoscale Microscopy and Molecular Physiology of the Brain; Alemania
Fil: Willig, Katrin I. Max Planck Institute for Biophysical Chemistry. Department of NanoBiophotonics; Alemania
Fil: Barrantes, Francisco José. Pontificia Universidad Católica Argentina. Facultad de Ciencias Médicas. Instituto de Investigaciones Biomédicas. Laboratorio de Neurobiología Molecular; Argentina
Fil: Barrantes, Francisco José. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Abstract: Chemical synapses in brain are structural differentiations where excitatory or inhibitory signals are vectorially transmitted between two neurons. Excitatory synapses occur mostly on dendritic spines, submicron sized protrusions of the neuronal dendritic arborizations. Axons establish contacts with these tiny specializations purported to be the smallest functional processing units in the central nervous system. The minute size of synapses and their macromolecular constituents creates an inherent difficulty for imaging but makes them an ideal object for superresolution microscopy. Here we discuss some representative examples of nanoscopy studies, ranging from quantification of receptors and scaffolding proteins in postsynaptic densities and their dynamic behavior, to imaging of synaptic vesicle proteins and dendritic spines in living neurons or even live animals.
description Fil: Willig, Katrin I. Center for Nanoscale Microscopy and Molecular Physiology of the Brain; Alemania
publishDate 2014
dc.date.none.fl_str_mv 2014
info:eu-repo/date/embargoEnd/2100-01-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://repositorio.uca.edu.ar/handle/123456789/15338
1367-5931
10.1016/j.cbpa.2014.03.021
24793373
Willig, K.I., Barrantes, F.J. Recent applications of superresolution microscopy in neurobiology [en línea]. Current Opinion in Chemical Biology. 2014. 20 doi:10.1016/j.cbpa.2014.03.021 Disponible en: https://repositorio.uca.edu.ar/handle/123456789/15338
url https://repositorio.uca.edu.ar/handle/123456789/15338
identifier_str_mv 1367-5931
10.1016/j.cbpa.2014.03.021
24793373
Willig, K.I., Barrantes, F.J. Recent applications of superresolution microscopy in neurobiology [en línea]. Current Opinion in Chemical Biology. 2014. 20 doi:10.1016/j.cbpa.2014.03.021 Disponible en: https://repositorio.uca.edu.ar/handle/123456789/15338
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/embargoedAccess
eu_rights_str_mv embargoedAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv Current Opinion in Chemical Biology. 2014. 20
reponame:Repositorio Institucional (UCA)
instname:Pontificia Universidad Católica Argentina
reponame_str Repositorio Institucional (UCA)
collection Repositorio Institucional (UCA)
instname_str Pontificia Universidad Católica Argentina
repository.name.fl_str_mv Repositorio Institucional (UCA) - Pontificia Universidad Católica Argentina
repository.mail.fl_str_mv claudia_fernandez@uca.edu.ar
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score 13.13397

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