Integration of transcriptomic and metabolic data reveals hub transcription factors involved in drought stress response in sunflower (Helianthus annuus L.)

Autores: Moschen, Sebastian Nicolas; Di Rienzo, Julio A.; Higgins, Janet; Tohge, Takayuki; Watanabe, Mutsumi; Gonzalez, Sergio Alberto; Rivarola, Maximo Lisandro; García-García, Francisco; Dopazo, Joaquín; Hopp, Horacio Esteban; Hoefgen, Rainer; Fernie, Alisdair R.; Paniego, Norma Beatriz; Fernandez, Paula Del Carmen; Heinz, Ruth Amelia
Año de publicación: 2017
Idioma: inglés
Tipo de recurso: artículo
Estado: versión publicada
Descripción: Drought is one of the most important environmental stresses that effects crop productivity in many agricultural regions. Sunflower is tolerant to drought conditions but the mechanisms involved in this tolerance remain unclear at the molecular level. The aim of this study was to characterize and integrate transcriptional and metabolic pathways related to drought stress in sunflower plants, by using a system biology approach. Our results showed a delay in plant senescence with an increase in the expression level of photosynthesis related genes as well as higher levels of sugars, osmoprotectant amino acids and ionic nutrients under drought conditions. In addition, we identified transcription factors that were upregulated during drought conditions and that may act as hubs in the transcriptional network. Many of these transcription factors belong to families implicated in the drought response in model species. The integration of transcriptomic and metabolomic data in this study, together with physiological measurements, has improved our understanding of the biological responses during droughts and contributes to elucidate the molecular mechanisms involved under this environmental condition. These findings will provide useful biotechnological tools to improve stress tolerance while maintaining crop yield under restricted water availability.
Instituto de Biotecnología
Fil: Moschen, Sebastian Nicolas. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Di Rienzo, Julio A.Universidad Nacional de Córdoba. Facultad de Ciencias Agropecuarias; Argentina
Fil: Higgins, Janet. Norwich Research Park. Earlham Institute; Reino Unido
Fil: Tohge, Takayuki. Max-Planck-Institut fur Molekulare Pflanzenphysiologie; Alemania
Fil: Watanabe, Mutsumi Max-Planck-Institut fur Molekulare Pflanzenphysiologie; Alemania
Fil: Gonzalez, Sergio Alberto. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Rivarola, Maximo Lisandro. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: García-García, Francisco. Centro de Investigación Príncipe Felipe. Department of Bioinformatics and Genomics; España. Centro de Investigación Príncipe Felipe . National Institute of Bioinformatics. Functional Genomics Node; España
Fil: Dopazo, Joaquín. Centro de Investigación Príncipe Felipe. Department of Bioinformatics and Genomics; España. Centro de Investigación Príncipe Felipe . National Institute of Bioinformatics. Functional Genomics Node; España
Fil: Hopp, Horacio Esteban. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina
Fil: Hoefgen, Rainer Max-Planck-Institut fur Molekulare Pflanzenphysiologie; Alemania
Fil: Fernie, Alisdair R. Max-Planck-Institut fur Molekulare Pflanzenphysiologie; Alemania
Fil: Paniego, Norma Beatriz. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Fernandez, Paula Del Carmen. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de San Martín. Escuela de Ciencia y Tecnología; Argentina
Fil: Heinz, Ruth Amelia. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina
Fuente: Plant molecular biology 94 (4–5) : 549–564. (July 2017)
Materia: Helianthus Annuus
Metabolismo
Genética
Sequía
Estrés de Sequia
Metabolism
Genetics
Drought
Drought Stress
Girasol
Nivel de accesibilidad: acceso restringido
Condiciones de uso
Repositorio
Institución: Instituto Nacional de Tecnología Agropecuaria
OAI Identificador: oai:localhost:20.500.12123/1960

Acceder

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spelling	Integration of transcriptomic and metabolic data reveals hub transcription factors involved in drought stress response in sunflower (Helianthus annuus L.)Moschen, Sebastian NicolasDi Rienzo, Julio A.Higgins, JanetTohge, TakayukiWatanabe, MutsumiGonzalez, Sergio AlbertoRivarola, Maximo LisandroGarcía-García, FranciscoDopazo, JoaquínHopp, Horacio EstebanHoefgen, RainerFernie, Alisdair R.Paniego, Norma BeatrizFernandez, Paula Del CarmenHeinz, Ruth AmeliaHelianthus AnnuusMetabolismoGenéticaSequíaEstrés de SequiaMetabolismGeneticsDroughtDrought StressGirasolDrought is one of the most important environmental stresses that effects crop productivity in many agricultural regions. Sunflower is tolerant to drought conditions but the mechanisms involved in this tolerance remain unclear at the molecular level. The aim of this study was to characterize and integrate transcriptional and metabolic pathways related to drought stress in sunflower plants, by using a system biology approach. Our results showed a delay in plant senescence with an increase in the expression level of photosynthesis related genes as well as higher levels of sugars, osmoprotectant amino acids and ionic nutrients under drought conditions. In addition, we identified transcription factors that were upregulated during drought conditions and that may act as hubs in the transcriptional network. Many of these transcription factors belong to families implicated in the drought response in model species. The integration of transcriptomic and metabolomic data in this study, together with physiological measurements, has improved our understanding of the biological responses during droughts and contributes to elucidate the molecular mechanisms involved under this environmental condition. These findings will provide useful biotechnological tools to improve stress tolerance while maintaining crop yield under restricted water availability.Instituto de BiotecnologíaFil: Moschen, Sebastian Nicolas. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Di Rienzo, Julio A.Universidad Nacional de Córdoba. Facultad de Ciencias Agropecuarias; ArgentinaFil: Higgins, Janet. Norwich Research Park. Earlham Institute; Reino UnidoFil: Tohge, Takayuki. Max-Planck-Institut fur Molekulare Pflanzenphysiologie; AlemaniaFil: Watanabe, Mutsumi Max-Planck-Institut fur Molekulare Pflanzenphysiologie; AlemaniaFil: Gonzalez, Sergio Alberto. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Rivarola, Maximo Lisandro. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: García-García, Francisco. Centro de Investigación Príncipe Felipe. Department of Bioinformatics and Genomics; España. Centro de Investigación Príncipe Felipe . National Institute of Bioinformatics. Functional Genomics Node; EspañaFil: Dopazo, Joaquín. Centro de Investigación Príncipe Felipe. Department of Bioinformatics and Genomics; España. Centro de Investigación Príncipe Felipe . National Institute of Bioinformatics. Functional Genomics Node; EspañaFil: Hopp, Horacio Esteban. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; ArgentinaFil: Hoefgen, Rainer Max-Planck-Institut fur Molekulare Pflanzenphysiologie; AlemaniaFil: Fernie, Alisdair R. Max-Planck-Institut fur Molekulare Pflanzenphysiologie; AlemaniaFil: Paniego, Norma Beatriz. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Fernandez, Paula Del Carmen. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de San Martín. Escuela de Ciencia y Tecnología; ArgentinaFil: Heinz, Ruth Amelia. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina2018-03-05T15:34:08Z2018-03-05T15:34:08Z2017-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://hdl.handle.net/20.500.12123/1960https://link.springer.com/article/10.1007/s11103-017-0625-50167-4412 (Print)1573-5028 (Online)https://doi.org/10.1007/s11103-017-0625-5Plant molecular biology 94 (4–5) : 549–564. 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dc.title.none.fl_str_mv	Integration of transcriptomic and metabolic data reveals hub transcription factors involved in drought stress response in sunflower (Helianthus annuus L.)
title	Integration of transcriptomic and metabolic data reveals hub transcription factors involved in drought stress response in sunflower (Helianthus annuus L.)
spellingShingle	Integration of transcriptomic and metabolic data reveals hub transcription factors involved in drought stress response in sunflower (Helianthus annuus L.) Moschen, Sebastian Nicolas Helianthus Annuus Metabolismo Genética Sequía Estrés de Sequia Metabolism Genetics Drought Drought Stress Girasol
title_short	Integration of transcriptomic and metabolic data reveals hub transcription factors involved in drought stress response in sunflower (Helianthus annuus L.)
title_full	Integration of transcriptomic and metabolic data reveals hub transcription factors involved in drought stress response in sunflower (Helianthus annuus L.)
title_fullStr	Integration of transcriptomic and metabolic data reveals hub transcription factors involved in drought stress response in sunflower (Helianthus annuus L.)
title_full_unstemmed	Integration of transcriptomic and metabolic data reveals hub transcription factors involved in drought stress response in sunflower (Helianthus annuus L.)
title_sort	Integration of transcriptomic and metabolic data reveals hub transcription factors involved in drought stress response in sunflower (Helianthus annuus L.)
dc.creator.none.fl_str_mv	Moschen, Sebastian Nicolas Di Rienzo, Julio A. Higgins, Janet Tohge, Takayuki Watanabe, Mutsumi Gonzalez, Sergio Alberto Rivarola, Maximo Lisandro García-García, Francisco Dopazo, Joaquín Hopp, Horacio Esteban Hoefgen, Rainer Fernie, Alisdair R. Paniego, Norma Beatriz Fernandez, Paula Del Carmen Heinz, Ruth Amelia
author	Moschen, Sebastian Nicolas
author_facet	Moschen, Sebastian Nicolas Di Rienzo, Julio A. Higgins, Janet Tohge, Takayuki Watanabe, Mutsumi Gonzalez, Sergio Alberto Rivarola, Maximo Lisandro García-García, Francisco Dopazo, Joaquín Hopp, Horacio Esteban Hoefgen, Rainer Fernie, Alisdair R. Paniego, Norma Beatriz Fernandez, Paula Del Carmen Heinz, Ruth Amelia
author_role	author
author2	Di Rienzo, Julio A. Higgins, Janet Tohge, Takayuki Watanabe, Mutsumi Gonzalez, Sergio Alberto Rivarola, Maximo Lisandro García-García, Francisco Dopazo, Joaquín Hopp, Horacio Esteban Hoefgen, Rainer Fernie, Alisdair R. Paniego, Norma Beatriz Fernandez, Paula Del Carmen Heinz, Ruth Amelia
author2_role	author author author author author author author author author author author author author author
dc.subject.none.fl_str_mv	Helianthus Annuus Metabolismo Genética Sequía Estrés de Sequia Metabolism Genetics Drought Drought Stress Girasol
topic	Helianthus Annuus Metabolismo Genética Sequía Estrés de Sequia Metabolism Genetics Drought Drought Stress Girasol
dc.description.none.fl_txt_mv	Drought is one of the most important environmental stresses that effects crop productivity in many agricultural regions. Sunflower is tolerant to drought conditions but the mechanisms involved in this tolerance remain unclear at the molecular level. The aim of this study was to characterize and integrate transcriptional and metabolic pathways related to drought stress in sunflower plants, by using a system biology approach. Our results showed a delay in plant senescence with an increase in the expression level of photosynthesis related genes as well as higher levels of sugars, osmoprotectant amino acids and ionic nutrients under drought conditions. In addition, we identified transcription factors that were upregulated during drought conditions and that may act as hubs in the transcriptional network. Many of these transcription factors belong to families implicated in the drought response in model species. The integration of transcriptomic and metabolomic data in this study, together with physiological measurements, has improved our understanding of the biological responses during droughts and contributes to elucidate the molecular mechanisms involved under this environmental condition. These findings will provide useful biotechnological tools to improve stress tolerance while maintaining crop yield under restricted water availability. Instituto de Biotecnología Fil: Moschen, Sebastian Nicolas. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Di Rienzo, Julio A.Universidad Nacional de Córdoba. Facultad de Ciencias Agropecuarias; Argentina Fil: Higgins, Janet. Norwich Research Park. Earlham Institute; Reino Unido Fil: Tohge, Takayuki. Max-Planck-Institut fur Molekulare Pflanzenphysiologie; Alemania Fil: Watanabe, Mutsumi Max-Planck-Institut fur Molekulare Pflanzenphysiologie; Alemania Fil: Gonzalez, Sergio Alberto. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Rivarola, Maximo Lisandro. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: García-García, Francisco. Centro de Investigación Príncipe Felipe. Department of Bioinformatics and Genomics; España. Centro de Investigación Príncipe Felipe . National Institute of Bioinformatics. Functional Genomics Node; España Fil: Dopazo, Joaquín. Centro de Investigación Príncipe Felipe. Department of Bioinformatics and Genomics; España. Centro de Investigación Príncipe Felipe . National Institute of Bioinformatics. Functional Genomics Node; España Fil: Hopp, Horacio Esteban. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina Fil: Hoefgen, Rainer Max-Planck-Institut fur Molekulare Pflanzenphysiologie; Alemania Fil: Fernie, Alisdair R. Max-Planck-Institut fur Molekulare Pflanzenphysiologie; Alemania Fil: Paniego, Norma Beatriz. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Fernandez, Paula Del Carmen. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de San Martín. Escuela de Ciencia y Tecnología; Argentina Fil: Heinz, Ruth Amelia. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina
description	Drought is one of the most important environmental stresses that effects crop productivity in many agricultural regions. Sunflower is tolerant to drought conditions but the mechanisms involved in this tolerance remain unclear at the molecular level. The aim of this study was to characterize and integrate transcriptional and metabolic pathways related to drought stress in sunflower plants, by using a system biology approach. Our results showed a delay in plant senescence with an increase in the expression level of photosynthesis related genes as well as higher levels of sugars, osmoprotectant amino acids and ionic nutrients under drought conditions. In addition, we identified transcription factors that were upregulated during drought conditions and that may act as hubs in the transcriptional network. Many of these transcription factors belong to families implicated in the drought response in model species. The integration of transcriptomic and metabolomic data in this study, together with physiological measurements, has improved our understanding of the biological responses during droughts and contributes to elucidate the molecular mechanisms involved under this environmental condition. These findings will provide useful biotechnological tools to improve stress tolerance while maintaining crop yield under restricted water availability.
publishDate	2017
dc.date.none.fl_str_mv	2017-07 2018-03-05T15:34:08Z 2018-03-05T15:34:08Z
dc.type.none.fl_str_mv	info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo
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dc.identifier.none.fl_str_mv	http://hdl.handle.net/20.500.12123/1960 https://link.springer.com/article/10.1007/s11103-017-0625-5 0167-4412 (Print) 1573-5028 (Online) https://doi.org/10.1007/s11103-017-0625-5
url	http://hdl.handle.net/20.500.12123/1960 https://link.springer.com/article/10.1007/s11103-017-0625-5 https://doi.org/10.1007/s11103-017-0625-5
identifier_str_mv	0167-4412 (Print) 1573-5028 (Online)
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dc.source.none.fl_str_mv	Plant molecular biology 94 (4–5) : 549–564. (July 2017) reponame:INTA Digital (INTA) instname:Instituto Nacional de Tecnología Agropecuaria
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Integration of transcriptomic and metabolic data reveals hub transcription factors involved in drought stress response in sunflower (Helianthus annuus L.)

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