Toxicities of glyphosate- and cypermethrin-based pesticides are antagonic in the tenspotted livebearer fish (Cnesterodon decemmaculatus)

Autores
Brodeur, Celine Marie Julie; Malpel, Solene; Anglesio, Ana Belén; Cristos, Diego Sebastian; D'Andrea, María Florencia; Poliserpi, Maria Belen
Año de publicación
2016
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Although pesticide contamination of surface waters normally occurs in the form of mixtures, the toxicity and interactions displayed by such mixtures have been little characterized until now. The present study examined the interactions prevailing in equitoxic and non-equitoxic binary mixtures of formulations of glyphosate (Glifoglex®) and cypermethrin (Glextrin®) to the tenspotted livebearer (Cnesterodon decemmaculatus), a widely distributed South American fish. The following 96 h-LC50s were obtained when pesticide formulations were tested individually: Glifoglex® 41.4 and 53 mg ae glyphosate/L; Glextrin® 1.89 and 2.60 mg cypermethrin/L. Equitoxic and non-equitoxic mixtures were significantly antagonic in all combinations tested. The magnitude of the antagonism (factor by which toxicity differed from concentration addition) varied between 1.37 and 3.09 times in the different non-equitoxic mixtures tested. Antagonism was due to a strong inhibition of cypermethrin toxicity by the glyphosate formulation, the toxicity of the cypermethrin-based pesticide being almost completely overridden by the glyphosate formulation. Results obtained in the current study with fish are radically opposite to those previously observed in tadpoles where synergy was observed when Glifoglex® and Glextrin® were present in mixtures (Brodeur et al., 2014).
Fil: Brodeur, Celine Marie Julie. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Recursos Bilológicos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.
Fil: Malpe, Solene. Université Paul Sabatier. Département Génie Biologique. Institut Universitaire de Technologie; Francia
Fil: Anglesio, Ana Belen. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Recursos Biológicos; Argentina
Fil: Cristos, Diego. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Tecnología de Alimentos; Argentina
Fil: D'Andrea, María Florencia. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Recursos Biológicos; Argentina
Fil: Poliserpi, María Belen. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Recursos Biológicos; Argentina
Fuente
Chemosphere 155 : 429-435. (2016)
Materia
Glifosato
Cipermetrin
Toxicidad de los Pesticidas
Peces
Glyphosate
Cypermethrin
Pesticide Toxicity
Fishes
Cnesterodon Decemmaculatus
Nivel de accesibilidad
acceso restringido
Condiciones de uso
Repositorio
INTA Digital (INTA)
Institución
Instituto Nacional de Tecnología Agropecuaria
OAI Identificador
oai:localhost:20.500.12123/2099
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oai_identifier_str oai:localhost:20.500.12123/2099
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spelling Toxicities of glyphosate- and cypermethrin-based pesticides are antagonic in the tenspotted livebearer fish (Cnesterodon decemmaculatus)Brodeur, Celine Marie JulieMalpel, SoleneAnglesio, Ana BelénCristos, Diego SebastianD'Andrea, María FlorenciaPoliserpi, Maria BelenGlifosatoCipermetrinToxicidad de los PesticidasPecesGlyphosateCypermethrinPesticide ToxicityFishesCnesterodon DecemmaculatusAlthough pesticide contamination of surface waters normally occurs in the form of mixtures, the toxicity and interactions displayed by such mixtures have been little characterized until now. The present study examined the interactions prevailing in equitoxic and non-equitoxic binary mixtures of formulations of glyphosate (Glifoglex®) and cypermethrin (Glextrin®) to the tenspotted livebearer (Cnesterodon decemmaculatus), a widely distributed South American fish. The following 96 h-LC50s were obtained when pesticide formulations were tested individually: Glifoglex® 41.4 and 53 mg ae glyphosate/L; Glextrin® 1.89 and 2.60 mg cypermethrin/L. Equitoxic and non-equitoxic mixtures were significantly antagonic in all combinations tested. The magnitude of the antagonism (factor by which toxicity differed from concentration addition) varied between 1.37 and 3.09 times in the different non-equitoxic mixtures tested. Antagonism was due to a strong inhibition of cypermethrin toxicity by the glyphosate formulation, the toxicity of the cypermethrin-based pesticide being almost completely overridden by the glyphosate formulation. Results obtained in the current study with fish are radically opposite to those previously observed in tadpoles where synergy was observed when Glifoglex® and Glextrin® were present in mixtures (Brodeur et al., 2014).Fil: Brodeur, Celine Marie Julie. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Recursos Bilológicos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.Fil: Malpe, Solene. Université Paul Sabatier. Département Génie Biologique. Institut Universitaire de Technologie; FranciaFil: Anglesio, Ana Belen. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Recursos Biológicos; ArgentinaFil: Cristos, Diego. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Tecnología de Alimentos; ArgentinaFil: D'Andrea, María Florencia. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Recursos Biológicos; ArgentinaFil: Poliserpi, María Belen. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Recursos Biológicos; Argentina2018-03-22T17:19:14Z2018-03-22T17:19:14Z2016info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://hdl.handle.net/20.500.12123/2099https://www.sciencedirect.com/science/article/pii/S00456535163056160045-6535https://doi.org/10.1016/j.chemosphere.2016.04.075Chemosphere 155 : 429-435. (2016)reponame:INTA Digital (INTA)instname:Instituto Nacional de Tecnología Agropecuariaenginfo:eu-repograntAgreement/INTA/PNNAT/1128041/AR./Gestion de sistemas agropecuarios y agroindustriales para reducir la contaminación.info:eu-repograntAgreement/INTA/PNNAT/1128043/AR./Los agroquímicos como fuente de contaminación difusa en agroecosistemas.info:eu-repo/semantics/restrictedAccess2025-09-29T13:44:16Zoai:localhost:20.500.12123/2099instacron:INTAInstitucionalhttp://repositorio.inta.gob.ar/Organismo científico-tecnológicoNo correspondehttp://repositorio.inta.gob.ar/oai/requesttripaldi.nicolas@inta.gob.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:l2025-09-29 13:44:16.706INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuariafalse
dc.title.none.fl_str_mv Toxicities of glyphosate- and cypermethrin-based pesticides are antagonic in the tenspotted livebearer fish (Cnesterodon decemmaculatus)
title Toxicities of glyphosate- and cypermethrin-based pesticides are antagonic in the tenspotted livebearer fish (Cnesterodon decemmaculatus)
spellingShingle Toxicities of glyphosate- and cypermethrin-based pesticides are antagonic in the tenspotted livebearer fish (Cnesterodon decemmaculatus)
Brodeur, Celine Marie Julie
Glifosato
Cipermetrin
Toxicidad de los Pesticidas
Peces
Glyphosate
Cypermethrin
Pesticide Toxicity
Fishes
Cnesterodon Decemmaculatus
title_short Toxicities of glyphosate- and cypermethrin-based pesticides are antagonic in the tenspotted livebearer fish (Cnesterodon decemmaculatus)
title_full Toxicities of glyphosate- and cypermethrin-based pesticides are antagonic in the tenspotted livebearer fish (Cnesterodon decemmaculatus)
title_fullStr Toxicities of glyphosate- and cypermethrin-based pesticides are antagonic in the tenspotted livebearer fish (Cnesterodon decemmaculatus)
title_full_unstemmed Toxicities of glyphosate- and cypermethrin-based pesticides are antagonic in the tenspotted livebearer fish (Cnesterodon decemmaculatus)
title_sort Toxicities of glyphosate- and cypermethrin-based pesticides are antagonic in the tenspotted livebearer fish (Cnesterodon decemmaculatus)
dc.creator.none.fl_str_mv Brodeur, Celine Marie Julie
Malpel, Solene
Anglesio, Ana Belén
Cristos, Diego Sebastian
D'Andrea, María Florencia
Poliserpi, Maria Belen
author Brodeur, Celine Marie Julie
author_facet Brodeur, Celine Marie Julie
Malpel, Solene
Anglesio, Ana Belén
Cristos, Diego Sebastian
D'Andrea, María Florencia
Poliserpi, Maria Belen
author_role author
author2 Malpel, Solene
Anglesio, Ana Belén
Cristos, Diego Sebastian
D'Andrea, María Florencia
Poliserpi, Maria Belen
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Glifosato
Cipermetrin
Toxicidad de los Pesticidas
Peces
Glyphosate
Cypermethrin
Pesticide Toxicity
Fishes
Cnesterodon Decemmaculatus
topic Glifosato
Cipermetrin
Toxicidad de los Pesticidas
Peces
Glyphosate
Cypermethrin
Pesticide Toxicity
Fishes
Cnesterodon Decemmaculatus
dc.description.none.fl_txt_mv Although pesticide contamination of surface waters normally occurs in the form of mixtures, the toxicity and interactions displayed by such mixtures have been little characterized until now. The present study examined the interactions prevailing in equitoxic and non-equitoxic binary mixtures of formulations of glyphosate (Glifoglex®) and cypermethrin (Glextrin®) to the tenspotted livebearer (Cnesterodon decemmaculatus), a widely distributed South American fish. The following 96 h-LC50s were obtained when pesticide formulations were tested individually: Glifoglex® 41.4 and 53 mg ae glyphosate/L; Glextrin® 1.89 and 2.60 mg cypermethrin/L. Equitoxic and non-equitoxic mixtures were significantly antagonic in all combinations tested. The magnitude of the antagonism (factor by which toxicity differed from concentration addition) varied between 1.37 and 3.09 times in the different non-equitoxic mixtures tested. Antagonism was due to a strong inhibition of cypermethrin toxicity by the glyphosate formulation, the toxicity of the cypermethrin-based pesticide being almost completely overridden by the glyphosate formulation. Results obtained in the current study with fish are radically opposite to those previously observed in tadpoles where synergy was observed when Glifoglex® and Glextrin® were present in mixtures (Brodeur et al., 2014).
Fil: Brodeur, Celine Marie Julie. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Recursos Bilológicos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.
Fil: Malpe, Solene. Université Paul Sabatier. Département Génie Biologique. Institut Universitaire de Technologie; Francia
Fil: Anglesio, Ana Belen. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Recursos Biológicos; Argentina
Fil: Cristos, Diego. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Tecnología de Alimentos; Argentina
Fil: D'Andrea, María Florencia. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Recursos Biológicos; Argentina
Fil: Poliserpi, María Belen. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Recursos Biológicos; Argentina
description Although pesticide contamination of surface waters normally occurs in the form of mixtures, the toxicity and interactions displayed by such mixtures have been little characterized until now. The present study examined the interactions prevailing in equitoxic and non-equitoxic binary mixtures of formulations of glyphosate (Glifoglex®) and cypermethrin (Glextrin®) to the tenspotted livebearer (Cnesterodon decemmaculatus), a widely distributed South American fish. The following 96 h-LC50s were obtained when pesticide formulations were tested individually: Glifoglex® 41.4 and 53 mg ae glyphosate/L; Glextrin® 1.89 and 2.60 mg cypermethrin/L. Equitoxic and non-equitoxic mixtures were significantly antagonic in all combinations tested. The magnitude of the antagonism (factor by which toxicity differed from concentration addition) varied between 1.37 and 3.09 times in the different non-equitoxic mixtures tested. Antagonism was due to a strong inhibition of cypermethrin toxicity by the glyphosate formulation, the toxicity of the cypermethrin-based pesticide being almost completely overridden by the glyphosate formulation. Results obtained in the current study with fish are radically opposite to those previously observed in tadpoles where synergy was observed when Glifoglex® and Glextrin® were present in mixtures (Brodeur et al., 2014).
publishDate 2016
dc.date.none.fl_str_mv 2016
2018-03-22T17:19:14Z
2018-03-22T17:19:14Z
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12123/2099
https://www.sciencedirect.com/science/article/pii/S0045653516305616
0045-6535
https://doi.org/10.1016/j.chemosphere.2016.04.075
url http://hdl.handle.net/20.500.12123/2099
https://www.sciencedirect.com/science/article/pii/S0045653516305616
https://doi.org/10.1016/j.chemosphere.2016.04.075
identifier_str_mv 0045-6535
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repograntAgreement/INTA/PNNAT/1128041/AR./Gestion de sistemas agropecuarios y agroindustriales para reducir la contaminación.
info:eu-repograntAgreement/INTA/PNNAT/1128043/AR./Los agroquímicos como fuente de contaminación difusa en agroecosistemas.
dc.rights.none.fl_str_mv info:eu-repo/semantics/restrictedAccess
eu_rights_str_mv restrictedAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv Chemosphere 155 : 429-435. (2016)
reponame:INTA Digital (INTA)
instname:Instituto Nacional de Tecnología Agropecuaria
reponame_str INTA Digital (INTA)
collection INTA Digital (INTA)
instname_str Instituto Nacional de Tecnología Agropecuaria
repository.name.fl_str_mv INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuaria
repository.mail.fl_str_mv tripaldi.nicolas@inta.gob.ar
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score 12.559606

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