Necrotic Enteritis in Young Calves

Autores
Morris, Winston Eduardo; Venzano, Agustin Jose; Elizondo, Ana Maria; Vilte, Daniel Alejandro; Mercado, Elsa Cristina; Fernandez Miyakawa, Mariano Enrique
Año de publicación
2011
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Non–enterotoxin (CPE)–producing Clostridium perfringens type A has been associated with enteritis in calves. Recent evidence has suggested that a novel toxin, named beta2 (CPB2), is implicated in the pathogenesis of this disease, although there is little evidence supporting this. In the current study, the role of C. perfringens type A in an outbreak of enteritis in calves was studied. Two 20-day-old dairy calves exhibiting apathy and reluctance to eat, with paresis of the anterior limbs, were euthanized for postmortem examination. Gross and histological changes compatible with acute enteritis, rumenitis, meningitis, and pneumonia were seen in both calves. Clostridium perfringens type A non-CPE, non-CPB2 was isolated from the abomasum and the small intestine. Escherichia coli ONT:H8 (with cdtBIII and f17 virulence genes detected by polymerase chain reaction) was also isolated from the brain, abomasum, and intestine from both calves. All the samples were negative for Salmonella spp. When the C. perfringens strain was inoculated into bovine ligated small and large intestinal loops, cell detachment, erosion, and hemorrhage of the lamina propria were observed, predominantly in the small intestine. The results suggest that non-CPE, non-CPB2 C. perfringens type A is able to induce pathologic changes in the intestine of calves, probably enhanced by other pathogens, such as some pathogenic E. coli strains.
Instituto de Patobiología
Fil: Morris, Winston Eduardo. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina
Fil: Venzano, Agustin Jose. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina
Fil: Elizondo, Ana Maria. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina
Fil: Vilte, Daniel Alejandro. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina
Fil: Mercado, Elsa Cristina. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina
Fil: Fernandez Miyakawa, Mariano Enrique. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina.
Fuente
Journal of Veterinary Diagnostic Investigation 23 (2) : 254-259. (March 2011)
Materia
Ganado Bovino
Ternero
Enfermedades de los Animales
Enterítis
Clostridium perfringens
Cattle
Calves
Animal Diseases
Enteritis
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
INTA Digital (INTA)
Institución
Instituto Nacional de Tecnología Agropecuaria
OAI Identificador
oai:localhost:20.500.12123/14430
Acceder
id INTADig_95e662a1671487abce240d8d776e82f8
oai_identifier_str oai:localhost:20.500.12123/14430
network_acronym_str INTADig
repository_id_str l
network_name_str INTA Digital (INTA)
spelling Necrotic Enteritis in Young CalvesMorris, Winston EduardoVenzano, Agustin JoseElizondo, Ana MariaVilte, Daniel AlejandroMercado, Elsa CristinaFernandez Miyakawa, Mariano EnriqueGanado BovinoTerneroEnfermedades de los AnimalesEnterítisClostridium perfringensCattleCalvesAnimal DiseasesEnteritisNon–enterotoxin (CPE)–producing Clostridium perfringens type A has been associated with enteritis in calves. Recent evidence has suggested that a novel toxin, named beta2 (CPB2), is implicated in the pathogenesis of this disease, although there is little evidence supporting this. In the current study, the role of C. perfringens type A in an outbreak of enteritis in calves was studied. Two 20-day-old dairy calves exhibiting apathy and reluctance to eat, with paresis of the anterior limbs, were euthanized for postmortem examination. Gross and histological changes compatible with acute enteritis, rumenitis, meningitis, and pneumonia were seen in both calves. Clostridium perfringens type A non-CPE, non-CPB2 was isolated from the abomasum and the small intestine. Escherichia coli ONT:H8 (with cdtBIII and f17 virulence genes detected by polymerase chain reaction) was also isolated from the brain, abomasum, and intestine from both calves. All the samples were negative for Salmonella spp. When the C. perfringens strain was inoculated into bovine ligated small and large intestinal loops, cell detachment, erosion, and hemorrhage of the lamina propria were observed, predominantly in the small intestine. The results suggest that non-CPE, non-CPB2 C. perfringens type A is able to induce pathologic changes in the intestine of calves, probably enhanced by other pathogens, such as some pathogenic E. coli strains.Instituto de PatobiologíaFil: Morris, Winston Eduardo. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; ArgentinaFil: Venzano, Agustin Jose. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; ArgentinaFil: Elizondo, Ana Maria. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; ArgentinaFil: Vilte, Daniel Alejandro. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; ArgentinaFil: Mercado, Elsa Cristina. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; ArgentinaFil: Fernandez Miyakawa, Mariano Enrique. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina.Sage Publishing2023-04-10T14:02:35Z2023-04-10T14:02:35Z2011-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://hdl.handle.net/20.500.12123/14430https://journals.sagepub.com/doi/full/10.1177/1040638711023002091040-63871943-4936https://doi.org/10.1177/104063871102300209Journal of Veterinary Diagnostic Investigation 23 (2) : 254-259. (March 2011)reponame:INTA Digital (INTA)instname:Instituto Nacional de Tecnología Agropecuariaenginfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)2025-09-04T09:49:47Zoai:localhost:20.500.12123/14430instacron:INTAInstitucionalhttp://repositorio.inta.gob.ar/Organismo científico-tecnológicoNo correspondehttp://repositorio.inta.gob.ar/oai/requesttripaldi.nicolas@inta.gob.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:l2025-09-04 09:49:47.992INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuariafalse
dc.title.none.fl_str_mv Necrotic Enteritis in Young Calves
title Necrotic Enteritis in Young Calves
spellingShingle Necrotic Enteritis in Young Calves
Morris, Winston Eduardo
Ganado Bovino
Ternero
Enfermedades de los Animales
Enterítis
Clostridium perfringens
Cattle
Calves
Animal Diseases
Enteritis
title_short Necrotic Enteritis in Young Calves
title_full Necrotic Enteritis in Young Calves
title_fullStr Necrotic Enteritis in Young Calves
title_full_unstemmed Necrotic Enteritis in Young Calves
title_sort Necrotic Enteritis in Young Calves
dc.creator.none.fl_str_mv Morris, Winston Eduardo
Venzano, Agustin Jose
Elizondo, Ana Maria
Vilte, Daniel Alejandro
Mercado, Elsa Cristina
Fernandez Miyakawa, Mariano Enrique
author Morris, Winston Eduardo
author_facet Morris, Winston Eduardo
Venzano, Agustin Jose
Elizondo, Ana Maria
Vilte, Daniel Alejandro
Mercado, Elsa Cristina
Fernandez Miyakawa, Mariano Enrique
author_role author
author2 Venzano, Agustin Jose
Elizondo, Ana Maria
Vilte, Daniel Alejandro
Mercado, Elsa Cristina
Fernandez Miyakawa, Mariano Enrique
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Ganado Bovino
Ternero
Enfermedades de los Animales
Enterítis
Clostridium perfringens
Cattle
Calves
Animal Diseases
Enteritis
topic Ganado Bovino
Ternero
Enfermedades de los Animales
Enterítis
Clostridium perfringens
Cattle
Calves
Animal Diseases
Enteritis
dc.description.none.fl_txt_mv Non–enterotoxin (CPE)–producing Clostridium perfringens type A has been associated with enteritis in calves. Recent evidence has suggested that a novel toxin, named beta2 (CPB2), is implicated in the pathogenesis of this disease, although there is little evidence supporting this. In the current study, the role of C. perfringens type A in an outbreak of enteritis in calves was studied. Two 20-day-old dairy calves exhibiting apathy and reluctance to eat, with paresis of the anterior limbs, were euthanized for postmortem examination. Gross and histological changes compatible with acute enteritis, rumenitis, meningitis, and pneumonia were seen in both calves. Clostridium perfringens type A non-CPE, non-CPB2 was isolated from the abomasum and the small intestine. Escherichia coli ONT:H8 (with cdtBIII and f17 virulence genes detected by polymerase chain reaction) was also isolated from the brain, abomasum, and intestine from both calves. All the samples were negative for Salmonella spp. When the C. perfringens strain was inoculated into bovine ligated small and large intestinal loops, cell detachment, erosion, and hemorrhage of the lamina propria were observed, predominantly in the small intestine. The results suggest that non-CPE, non-CPB2 C. perfringens type A is able to induce pathologic changes in the intestine of calves, probably enhanced by other pathogens, such as some pathogenic E. coli strains.
Instituto de Patobiología
Fil: Morris, Winston Eduardo. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina
Fil: Venzano, Agustin Jose. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina
Fil: Elizondo, Ana Maria. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina
Fil: Vilte, Daniel Alejandro. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina
Fil: Mercado, Elsa Cristina. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina
Fil: Fernandez Miyakawa, Mariano Enrique. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina.
description Non–enterotoxin (CPE)–producing Clostridium perfringens type A has been associated with enteritis in calves. Recent evidence has suggested that a novel toxin, named beta2 (CPB2), is implicated in the pathogenesis of this disease, although there is little evidence supporting this. In the current study, the role of C. perfringens type A in an outbreak of enteritis in calves was studied. Two 20-day-old dairy calves exhibiting apathy and reluctance to eat, with paresis of the anterior limbs, were euthanized for postmortem examination. Gross and histological changes compatible with acute enteritis, rumenitis, meningitis, and pneumonia were seen in both calves. Clostridium perfringens type A non-CPE, non-CPB2 was isolated from the abomasum and the small intestine. Escherichia coli ONT:H8 (with cdtBIII and f17 virulence genes detected by polymerase chain reaction) was also isolated from the brain, abomasum, and intestine from both calves. All the samples were negative for Salmonella spp. When the C. perfringens strain was inoculated into bovine ligated small and large intestinal loops, cell detachment, erosion, and hemorrhage of the lamina propria were observed, predominantly in the small intestine. The results suggest that non-CPE, non-CPB2 C. perfringens type A is able to induce pathologic changes in the intestine of calves, probably enhanced by other pathogens, such as some pathogenic E. coli strains.
publishDate 2011
dc.date.none.fl_str_mv 2011-03
2023-04-10T14:02:35Z
2023-04-10T14:02:35Z
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12123/14430
https://journals.sagepub.com/doi/full/10.1177/104063871102300209
1040-6387
1943-4936
https://doi.org/10.1177/104063871102300209
url http://hdl.handle.net/20.500.12123/14430
https://journals.sagepub.com/doi/full/10.1177/104063871102300209
https://doi.org/10.1177/104063871102300209
identifier_str_mv 1040-6387
1943-4936
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sage Publishing
publisher.none.fl_str_mv Sage Publishing
dc.source.none.fl_str_mv Journal of Veterinary Diagnostic Investigation 23 (2) : 254-259. (March 2011)
reponame:INTA Digital (INTA)
instname:Instituto Nacional de Tecnología Agropecuaria
reponame_str INTA Digital (INTA)
collection INTA Digital (INTA)
instname_str Instituto Nacional de Tecnología Agropecuaria
repository.name.fl_str_mv INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuaria
repository.mail.fl_str_mv tripaldi.nicolas@inta.gob.ar
_version_ 1842341409980416000
score 12.623145

Publicaciones similares