Mycobacterium bovis infection in cats: Zoonotic transmission

Autores
Barandiaran, Soledad; Marfil, Maria Jimena; Yaafar, Natalia; Ferrer, María Fernanda; Fajardo, Sandra; Salvador, María Fernanda; Biscia, Mariana; Zumarraga, Martin Jose; Sarradell, Javier Eduardo
Año de publicación
2025
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Tuberculosis caused by Mycobacterium bovis is an infectious disease of worldwide relevance, with a growing concern for its zoonotic potential. Although cattle are the primary host, infections in companion animals have been reported, raising new public health concerns. Methods: Four cases of M. bovis infection in two cohabiting cats and two humans, one being the pet owner and the other a veterinarian, are analysed. Microbiological and molecular diagnostic techniques were employed, including culture, PCR, and genotyping through spoligotyping. Results: The presence of M. bovis was confirmed in both felines, identifying the same spoligotype (SB0140). Subsequently, the infection was documented in the pet owner, who had no history of contact with livestock, and in a veterinarian who sustained a needlestick injury during sample collection. Conclusions: These findings highlight the risk of zoonotic tuberculosis originating from companion animals, even in the absence of direct exposure to livestock. The results underscore the need to strengthen diagnostic and surveillance strategies in non-traditional species and emphasise the importance of adopting a comprehensive One Health approach to prevent and mitigate transmission between animals and humans, particularly in regions where bovine tuberculosis is endemic.
Instituto de Biotecnología
Fil: Barandiaran, Soledad. Universidad de Buenos Aires (UBA). Instituto de Investigaciones en Producción Animal (INPA); Argentina
Fil: Barandiaran, Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET). Instituto de Investigaciones en Producción Animal (INPA); Argentina
Fil: Barandiaran, Soledad. Universidad de Buenos Aires (UBA). Facultad de Ciencias Veterinarias; Argentina
Fil: Marfil, Maria Jimena. Universidad de Buenos Aires (UBA). Facultad de Ciencias Veterinarias; Argentina
Fil: Yaafar, Natalia. Universidad Nacional de Rosario (UNR). Facultad Ciencias Veterinarias; Argentina
Fil: Ferrer, María Fernanda. Programa de Epidemiología de la Provincia de Santa Fe; Argentina
Fil: Ferrer, María Fernanda. Hospital Privado de Rosario; Argentina
Fil: Fajardo, Sandra. Centro Regional de Estudios bioquímicos de la Tuberculosis de Rosario; Argentina
Fil: Salvador, María Fernanda. Laboratorio Veterinario Salvador; Argentina
Fil: Biscia, Mariana. Universidad Nacional de Rosario (UNR). Facultad de Ciencias Veterinarias; Argentina
Fil: Zumarraga, Martin Jose. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular; Argentina
Fil: Zumarraga, Martin Jose. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET). Instituto de Agrobiotecnología y Biología Molecular; Argentina
Fil: Sarradell, Javier Eduardo. Universidad Nacional de Rosario (UNR). Facultad de Ciencias Veterinarias; Argentina
Fuente
Zoonoses and Public Health 72 (7) : 683-689 (First published: 25 August 2025)
Materia
Gato
Mycobacterium bovis
Zoonosis
Tuberculosis
Transmisión de Enfermedades
Cats
Zoonoses
Disease Transmission
Zoonotic Transmission
Nivel de accesibilidad
acceso restringido
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
INTA Digital (INTA)
Institución
Instituto Nacional de Tecnología Agropecuaria
OAI Identificador
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spelling Mycobacterium bovis infection in cats: Zoonotic transmissionBarandiaran, SoledadMarfil, Maria JimenaYaafar, NataliaFerrer, María FernandaFajardo, SandraSalvador, María FernandaBiscia, MarianaZumarraga, Martin JoseSarradell, Javier EduardoGatoMycobacterium bovisZoonosisTuberculosisTransmisión de EnfermedadesCatsZoonosesDisease TransmissionZoonotic TransmissionTuberculosis caused by Mycobacterium bovis is an infectious disease of worldwide relevance, with a growing concern for its zoonotic potential. Although cattle are the primary host, infections in companion animals have been reported, raising new public health concerns. Methods: Four cases of M. bovis infection in two cohabiting cats and two humans, one being the pet owner and the other a veterinarian, are analysed. Microbiological and molecular diagnostic techniques were employed, including culture, PCR, and genotyping through spoligotyping. Results: The presence of M. bovis was confirmed in both felines, identifying the same spoligotype (SB0140). Subsequently, the infection was documented in the pet owner, who had no history of contact with livestock, and in a veterinarian who sustained a needlestick injury during sample collection. Conclusions: These findings highlight the risk of zoonotic tuberculosis originating from companion animals, even in the absence of direct exposure to livestock. The results underscore the need to strengthen diagnostic and surveillance strategies in non-traditional species and emphasise the importance of adopting a comprehensive One Health approach to prevent and mitigate transmission between animals and humans, particularly in regions where bovine tuberculosis is endemic.Instituto de BiotecnologíaFil: Barandiaran, Soledad. Universidad de Buenos Aires (UBA). Instituto de Investigaciones en Producción Animal (INPA); ArgentinaFil: Barandiaran, Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET). Instituto de Investigaciones en Producción Animal (INPA); ArgentinaFil: Barandiaran, Soledad. Universidad de Buenos Aires (UBA). Facultad de Ciencias Veterinarias; ArgentinaFil: Marfil, Maria Jimena. Universidad de Buenos Aires (UBA). Facultad de Ciencias Veterinarias; ArgentinaFil: Yaafar, Natalia. Universidad Nacional de Rosario (UNR). Facultad Ciencias Veterinarias; ArgentinaFil: Ferrer, María Fernanda. Programa de Epidemiología de la Provincia de Santa Fe; ArgentinaFil: Ferrer, María Fernanda. Hospital Privado de Rosario; ArgentinaFil: Fajardo, Sandra. Centro Regional de Estudios bioquímicos de la Tuberculosis de Rosario; ArgentinaFil: Salvador, María Fernanda. Laboratorio Veterinario Salvador; ArgentinaFil: Biscia, Mariana. Universidad Nacional de Rosario (UNR). Facultad de Ciencias Veterinarias; ArgentinaFil: Zumarraga, Martin Jose. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular; ArgentinaFil: Zumarraga, Martin Jose. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET). Instituto de Agrobiotecnología y Biología Molecular; ArgentinaFil: Sarradell, Javier Eduardo. Universidad Nacional de Rosario (UNR). Facultad de Ciencias Veterinarias; ArgentinaWiley2025-12-26T16:54:38Z2025-12-26T16:54:38Z2025-08-25info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://hdl.handle.net/20.500.12123/24776https://onlinelibrary.wiley.com/doi/full/10.1111/zph.700081863-2378 (online)1863-1959 (impreso)https://doi.org/10.1111/zph.70008Zoonoses and Public Health 72 (7) : 683-689 (First published: 25 August 2025)reponame:INTA Digital (INTA)instname:Instituto Nacional de Tecnología Agropecuariaenginfo:eu-repo/semantics/restrictedAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)2026-02-26T11:47:38Zoai:localhost:20.500.12123/24776instacron:INTAInstitucionalhttp://repositorio.inta.gob.ar/Organismo científico-tecnológicoNo correspondehttp://repositorio.inta.gob.ar/oai/requesttripaldi.nicolas@inta.gob.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:l2026-02-26 11:47:38.86INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuariafalse
dc.title.none.fl_str_mv Mycobacterium bovis infection in cats: Zoonotic transmission
title Mycobacterium bovis infection in cats: Zoonotic transmission
spellingShingle Mycobacterium bovis infection in cats: Zoonotic transmission
Barandiaran, Soledad
Gato
Mycobacterium bovis
Zoonosis
Tuberculosis
Transmisión de Enfermedades
Cats
Zoonoses
Disease Transmission
Zoonotic Transmission
title_short Mycobacterium bovis infection in cats: Zoonotic transmission
title_full Mycobacterium bovis infection in cats: Zoonotic transmission
title_fullStr Mycobacterium bovis infection in cats: Zoonotic transmission
title_full_unstemmed Mycobacterium bovis infection in cats: Zoonotic transmission
title_sort Mycobacterium bovis infection in cats: Zoonotic transmission
dc.creator.none.fl_str_mv Barandiaran, Soledad
Marfil, Maria Jimena
Yaafar, Natalia
Ferrer, María Fernanda
Fajardo, Sandra
Salvador, María Fernanda
Biscia, Mariana
Zumarraga, Martin Jose
Sarradell, Javier Eduardo
author Barandiaran, Soledad
author_facet Barandiaran, Soledad
Marfil, Maria Jimena
Yaafar, Natalia
Ferrer, María Fernanda
Fajardo, Sandra
Salvador, María Fernanda
Biscia, Mariana
Zumarraga, Martin Jose
Sarradell, Javier Eduardo
author_role author
author2 Marfil, Maria Jimena
Yaafar, Natalia
Ferrer, María Fernanda
Fajardo, Sandra
Salvador, María Fernanda
Biscia, Mariana
Zumarraga, Martin Jose
Sarradell, Javier Eduardo
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Gato
Mycobacterium bovis
Zoonosis
Tuberculosis
Transmisión de Enfermedades
Cats
Zoonoses
Disease Transmission
Zoonotic Transmission
topic Gato
Mycobacterium bovis
Zoonosis
Tuberculosis
Transmisión de Enfermedades
Cats
Zoonoses
Disease Transmission
Zoonotic Transmission
dc.description.none.fl_txt_mv Tuberculosis caused by Mycobacterium bovis is an infectious disease of worldwide relevance, with a growing concern for its zoonotic potential. Although cattle are the primary host, infections in companion animals have been reported, raising new public health concerns. Methods: Four cases of M. bovis infection in two cohabiting cats and two humans, one being the pet owner and the other a veterinarian, are analysed. Microbiological and molecular diagnostic techniques were employed, including culture, PCR, and genotyping through spoligotyping. Results: The presence of M. bovis was confirmed in both felines, identifying the same spoligotype (SB0140). Subsequently, the infection was documented in the pet owner, who had no history of contact with livestock, and in a veterinarian who sustained a needlestick injury during sample collection. Conclusions: These findings highlight the risk of zoonotic tuberculosis originating from companion animals, even in the absence of direct exposure to livestock. The results underscore the need to strengthen diagnostic and surveillance strategies in non-traditional species and emphasise the importance of adopting a comprehensive One Health approach to prevent and mitigate transmission between animals and humans, particularly in regions where bovine tuberculosis is endemic.
Instituto de Biotecnología
Fil: Barandiaran, Soledad. Universidad de Buenos Aires (UBA). Instituto de Investigaciones en Producción Animal (INPA); Argentina
Fil: Barandiaran, Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET). Instituto de Investigaciones en Producción Animal (INPA); Argentina
Fil: Barandiaran, Soledad. Universidad de Buenos Aires (UBA). Facultad de Ciencias Veterinarias; Argentina
Fil: Marfil, Maria Jimena. Universidad de Buenos Aires (UBA). Facultad de Ciencias Veterinarias; Argentina
Fil: Yaafar, Natalia. Universidad Nacional de Rosario (UNR). Facultad Ciencias Veterinarias; Argentina
Fil: Ferrer, María Fernanda. Programa de Epidemiología de la Provincia de Santa Fe; Argentina
Fil: Ferrer, María Fernanda. Hospital Privado de Rosario; Argentina
Fil: Fajardo, Sandra. Centro Regional de Estudios bioquímicos de la Tuberculosis de Rosario; Argentina
Fil: Salvador, María Fernanda. Laboratorio Veterinario Salvador; Argentina
Fil: Biscia, Mariana. Universidad Nacional de Rosario (UNR). Facultad de Ciencias Veterinarias; Argentina
Fil: Zumarraga, Martin Jose. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular; Argentina
Fil: Zumarraga, Martin Jose. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET). Instituto de Agrobiotecnología y Biología Molecular; Argentina
Fil: Sarradell, Javier Eduardo. Universidad Nacional de Rosario (UNR). Facultad de Ciencias Veterinarias; Argentina
description Tuberculosis caused by Mycobacterium bovis is an infectious disease of worldwide relevance, with a growing concern for its zoonotic potential. Although cattle are the primary host, infections in companion animals have been reported, raising new public health concerns. Methods: Four cases of M. bovis infection in two cohabiting cats and two humans, one being the pet owner and the other a veterinarian, are analysed. Microbiological and molecular diagnostic techniques were employed, including culture, PCR, and genotyping through spoligotyping. Results: The presence of M. bovis was confirmed in both felines, identifying the same spoligotype (SB0140). Subsequently, the infection was documented in the pet owner, who had no history of contact with livestock, and in a veterinarian who sustained a needlestick injury during sample collection. Conclusions: These findings highlight the risk of zoonotic tuberculosis originating from companion animals, even in the absence of direct exposure to livestock. The results underscore the need to strengthen diagnostic and surveillance strategies in non-traditional species and emphasise the importance of adopting a comprehensive One Health approach to prevent and mitigate transmission between animals and humans, particularly in regions where bovine tuberculosis is endemic.
publishDate 2025
dc.date.none.fl_str_mv 2025-12-26T16:54:38Z
2025-12-26T16:54:38Z
2025-08-25
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12123/24776
https://onlinelibrary.wiley.com/doi/full/10.1111/zph.70008
1863-2378 (online)
1863-1959 (impreso)
https://doi.org/10.1111/zph.70008
url http://hdl.handle.net/20.500.12123/24776
https://onlinelibrary.wiley.com/doi/full/10.1111/zph.70008
https://doi.org/10.1111/zph.70008
identifier_str_mv 1863-2378 (online)
1863-1959 (impreso)
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/restrictedAccess
http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv restrictedAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv Zoonoses and Public Health 72 (7) : 683-689 (First published: 25 August 2025)
reponame:INTA Digital (INTA)
instname:Instituto Nacional de Tecnología Agropecuaria
reponame_str INTA Digital (INTA)
collection INTA Digital (INTA)
instname_str Instituto Nacional de Tecnología Agropecuaria
repository.name.fl_str_mv INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuaria
repository.mail.fl_str_mv tripaldi.nicolas@inta.gob.ar
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