Which are important targets in development of S. aureus mastitis vaccine?
- Autores
- Scali, F.; Camussone, Cecilia; Calvinho, Luis Fernando; Cipolla, M.; Zecconi, A.
- Año de publicación
- 2015
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Staphylococcus aureus represents one of the leading causes of mastitis in dairy cows worldwide. S. aureus IMI have variable outcomes due to virulence of the strain involved, immune defenses of the host, and by antibiotic resistance. The difficulty in eradication and the increasing concerns on antibiotics usages underscore the interest in developing new tools to control S. aureus mastitis. Vaccination represents one of the most studied of these tools but, so far, no vaccine seems to provide reliable protection. This review summarizes current knowledge on the major vaccine targets, including surface proteins, capsular polysaccharides, biofilm, and toxins. Finally, the present status of vaccination against S. aureus and the future of vaccine design were discussed, including how differences among in vivo models may influence vaccines development.
EEA Rafaela
Fil: Scali, F. Universita Degli Studi Di Milano. Department of Veterinary Sciences and Public Health; Italia
Fil: Camussone, Cecilia. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.
Fil: Calvinho, Luis Fernando. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias; Argentina
Fil: Cipolla, M. Universita Degli Studi Di Milano. Department of Veterinary Sciences and Public Health; Italia
Fil: Zecconi, A. Universita Degli Studi Di Milano. Department of Veterinary Sciences and Public Health; Italia - Fuente
- Research in Veterinary Science 100 : 88-99 (June 2015)
- Materia
-
Mastítis Bovina
Enfermedades de los Animales
Ganado Bovino
Control de Enfermedades
Vacuna
Staphylococcus aureus
Bovine Mastitis
Animal Diseases
Cattle
Disease Control
Vaccines - Nivel de accesibilidad
- acceso restringido
- Condiciones de uso
- Repositorio
- Institución
- Instituto Nacional de Tecnología Agropecuaria
- OAI Identificador
- oai:localhost:20.500.12123/2825
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Which are important targets in development of S. aureus mastitis vaccine?Scali, F.Camussone, CeciliaCalvinho, Luis FernandoCipolla, M.Zecconi, A.Mastítis BovinaEnfermedades de los AnimalesGanado BovinoControl de EnfermedadesVacunaStaphylococcus aureusBovine MastitisAnimal DiseasesCattleDisease ControlVaccinesStaphylococcus aureus represents one of the leading causes of mastitis in dairy cows worldwide. S. aureus IMI have variable outcomes due to virulence of the strain involved, immune defenses of the host, and by antibiotic resistance. The difficulty in eradication and the increasing concerns on antibiotics usages underscore the interest in developing new tools to control S. aureus mastitis. Vaccination represents one of the most studied of these tools but, so far, no vaccine seems to provide reliable protection. This review summarizes current knowledge on the major vaccine targets, including surface proteins, capsular polysaccharides, biofilm, and toxins. Finally, the present status of vaccination against S. aureus and the future of vaccine design were discussed, including how differences among in vivo models may influence vaccines development.EEA RafaelaFil: Scali, F. Universita Degli Studi Di Milano. Department of Veterinary Sciences and Public Health; ItaliaFil: Camussone, Cecilia. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina.Fil: Calvinho, Luis Fernando. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias; ArgentinaFil: Cipolla, M. Universita Degli Studi Di Milano. Department of Veterinary Sciences and Public Health; ItaliaFil: Zecconi, A. Universita Degli Studi Di Milano. Department of Veterinary Sciences and Public Health; Italia2018-07-19T13:46:49Z2018-07-19T13:46:49Z2015-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttps://www.sciencedirect.com/science/article/pii/S0034528815000934?via%3Dihubhttp://hdl.handle.net/20.500.12123/28250034-5288https://doi.org/10.1016/j.rvsc.2015.03.019Research in Veterinary Science 100 : 88-99 (June 2015)reponame:INTA Digital (INTA)instname:Instituto Nacional de Tecnología Agropecuariaenginfo:eu-repo/semantics/restrictedAccess2025-09-29T13:44:21Zoai:localhost:20.500.12123/2825instacron:INTAInstitucionalhttp://repositorio.inta.gob.ar/Organismo científico-tecnológicoNo correspondehttp://repositorio.inta.gob.ar/oai/requesttripaldi.nicolas@inta.gob.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:l2025-09-29 13:44:22.281INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuariafalse |
dc.title.none.fl_str_mv |
Which are important targets in development of S. aureus mastitis vaccine? |
title |
Which are important targets in development of S. aureus mastitis vaccine? |
spellingShingle |
Which are important targets in development of S. aureus mastitis vaccine? Scali, F. Mastítis Bovina Enfermedades de los Animales Ganado Bovino Control de Enfermedades Vacuna Staphylococcus aureus Bovine Mastitis Animal Diseases Cattle Disease Control Vaccines |
title_short |
Which are important targets in development of S. aureus mastitis vaccine? |
title_full |
Which are important targets in development of S. aureus mastitis vaccine? |
title_fullStr |
Which are important targets in development of S. aureus mastitis vaccine? |
title_full_unstemmed |
Which are important targets in development of S. aureus mastitis vaccine? |
title_sort |
Which are important targets in development of S. aureus mastitis vaccine? |
dc.creator.none.fl_str_mv |
Scali, F. Camussone, Cecilia Calvinho, Luis Fernando Cipolla, M. Zecconi, A. |
author |
Scali, F. |
author_facet |
Scali, F. Camussone, Cecilia Calvinho, Luis Fernando Cipolla, M. Zecconi, A. |
author_role |
author |
author2 |
Camussone, Cecilia Calvinho, Luis Fernando Cipolla, M. Zecconi, A. |
author2_role |
author author author author |
dc.subject.none.fl_str_mv |
Mastítis Bovina Enfermedades de los Animales Ganado Bovino Control de Enfermedades Vacuna Staphylococcus aureus Bovine Mastitis Animal Diseases Cattle Disease Control Vaccines |
topic |
Mastítis Bovina Enfermedades de los Animales Ganado Bovino Control de Enfermedades Vacuna Staphylococcus aureus Bovine Mastitis Animal Diseases Cattle Disease Control Vaccines |
dc.description.none.fl_txt_mv |
Staphylococcus aureus represents one of the leading causes of mastitis in dairy cows worldwide. S. aureus IMI have variable outcomes due to virulence of the strain involved, immune defenses of the host, and by antibiotic resistance. The difficulty in eradication and the increasing concerns on antibiotics usages underscore the interest in developing new tools to control S. aureus mastitis. Vaccination represents one of the most studied of these tools but, so far, no vaccine seems to provide reliable protection. This review summarizes current knowledge on the major vaccine targets, including surface proteins, capsular polysaccharides, biofilm, and toxins. Finally, the present status of vaccination against S. aureus and the future of vaccine design were discussed, including how differences among in vivo models may influence vaccines development. EEA Rafaela Fil: Scali, F. Universita Degli Studi Di Milano. Department of Veterinary Sciences and Public Health; Italia Fil: Camussone, Cecilia. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fil: Calvinho, Luis Fernando. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias; Argentina Fil: Cipolla, M. Universita Degli Studi Di Milano. Department of Veterinary Sciences and Public Health; Italia Fil: Zecconi, A. Universita Degli Studi Di Milano. Department of Veterinary Sciences and Public Health; Italia |
description |
Staphylococcus aureus represents one of the leading causes of mastitis in dairy cows worldwide. S. aureus IMI have variable outcomes due to virulence of the strain involved, immune defenses of the host, and by antibiotic resistance. The difficulty in eradication and the increasing concerns on antibiotics usages underscore the interest in developing new tools to control S. aureus mastitis. Vaccination represents one of the most studied of these tools but, so far, no vaccine seems to provide reliable protection. This review summarizes current knowledge on the major vaccine targets, including surface proteins, capsular polysaccharides, biofilm, and toxins. Finally, the present status of vaccination against S. aureus and the future of vaccine design were discussed, including how differences among in vivo models may influence vaccines development. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-06 2018-07-19T13:46:49Z 2018-07-19T13:46:49Z |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
https://www.sciencedirect.com/science/article/pii/S0034528815000934?via%3Dihub http://hdl.handle.net/20.500.12123/2825 0034-5288 https://doi.org/10.1016/j.rvsc.2015.03.019 |
url |
https://www.sciencedirect.com/science/article/pii/S0034528815000934?via%3Dihub http://hdl.handle.net/20.500.12123/2825 https://doi.org/10.1016/j.rvsc.2015.03.019 |
identifier_str_mv |
0034-5288 |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/restrictedAccess |
eu_rights_str_mv |
restrictedAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
Research in Veterinary Science 100 : 88-99 (June 2015) reponame:INTA Digital (INTA) instname:Instituto Nacional de Tecnología Agropecuaria |
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INTA Digital (INTA) |
collection |
INTA Digital (INTA) |
instname_str |
Instituto Nacional de Tecnología Agropecuaria |
repository.name.fl_str_mv |
INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuaria |
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tripaldi.nicolas@inta.gob.ar |
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