Congenital hypovitaminosis A in dairy cattle

Autores
Sosa, Emiliano; Morrell, Eleonora Lidia; Llada, Ignacio Mariano; Odriozola, Ernesto Raul; Canton, German Jose
Año de publicación
2023
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Hypovitaminosis A negatively impacts the health of ruminants feeding on low-fresh forage diets for long periods of time. Although this disease is characterised by different clinical presentations, its congenital form is underreported. Here, we describe an outbreak of vitamin A deficiency that affected 30% of calves born in a dairy heifer herd. At birth, the affected animals showed weakness, ataxia, mydriasis, bluish coloration of the tapetum lacidum and blindness as the main clinical signs. The gross pathological findings at postmortem examination revealed cerebellar herniation, flattened gyri and narrowed sulci of the cerebral cortex in an affected calf. Histopathology showed squamous metaplasia of the efferent ducts in the parotid gland and hyperkeratosis of the ruminal mucosa. In addition, the plasma levels of vitamin A in the heifers and calves were below the reference values. These results confirmed the first reported case of congenital hypovitaminosis A in cattle in Argentina.
EEA Balcarce
Fil: Sosa, Emiliano. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina.
Fil: Sosa, Emiliano. Universidad Nacional de La Pampa. Facultad de Ciencias Veterinarias; Argentina.
Fil: Morrell, Eleonora L. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina.
Fil: Llada, Ignacio. University of Georgia. Department of Physiology and Pharmacology. Interdisciplinary Toxicology Program; Estados Unidos.
Fil: Odriozola, Ernesto Raúl. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina.
Fil: Cantón Germán José. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina.
Fuente
Veterinary Record Case Reports : e744 (2023)
Materia
Ceguera
Ternero
Deficiencia de Vitaminas
Ganado de Leche
Blindness
Calves
Vitamin Deficiencies
Metaplasia
Dairy Cattle
Nivel de accesibilidad
acceso restringido
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
INTA Digital (INTA)
Institución
Instituto Nacional de Tecnología Agropecuaria
OAI Identificador
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spelling Congenital hypovitaminosis A in dairy cattleSosa, EmilianoMorrell, Eleonora LidiaLlada, Ignacio MarianoOdriozola, Ernesto RaulCanton, German JoseCegueraTerneroDeficiencia de VitaminasGanado de LecheBlindnessCalvesVitamin DeficienciesMetaplasiaDairy CattleHypovitaminosis A negatively impacts the health of ruminants feeding on low-fresh forage diets for long periods of time. Although this disease is characterised by different clinical presentations, its congenital form is underreported. Here, we describe an outbreak of vitamin A deficiency that affected 30% of calves born in a dairy heifer herd. At birth, the affected animals showed weakness, ataxia, mydriasis, bluish coloration of the tapetum lacidum and blindness as the main clinical signs. The gross pathological findings at postmortem examination revealed cerebellar herniation, flattened gyri and narrowed sulci of the cerebral cortex in an affected calf. Histopathology showed squamous metaplasia of the efferent ducts in the parotid gland and hyperkeratosis of the ruminal mucosa. In addition, the plasma levels of vitamin A in the heifers and calves were below the reference values. These results confirmed the first reported case of congenital hypovitaminosis A in cattle in Argentina.EEA BalcarceFil: Sosa, Emiliano. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina.Fil: Sosa, Emiliano. Universidad Nacional de La Pampa. Facultad de Ciencias Veterinarias; Argentina.Fil: Morrell, Eleonora L. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina.Fil: Llada, Ignacio. University of Georgia. Department of Physiology and Pharmacology. Interdisciplinary Toxicology Program; Estados Unidos.Fil: Odriozola, Ernesto Raúl. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina.Fil: Cantón Germán José. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina.British Veterinary Association2023-10-09T15:55:10Z2023-10-09T15:55:10Z2023-10-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://hdl.handle.net/20.500.12123/15484https://bvajournals.onlinelibrary.wiley.com/doi/10.1002/vrc2.7442052-6121https://doi.org/10.1002/vrc2.744Veterinary Record Case Reports : e744 (2023)reponame:INTA Digital (INTA)instname:Instituto Nacional de Tecnología Agropecuariaenginfo:eu-repograntAgreement/INTA/2019-RIST-E5-I111-001, Laboratorios de Diagnóstico Veterinarioinfo:eu-repo/semantics/restrictedAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)2025-10-16T09:31:19Zoai:localhost:20.500.12123/15484instacron:INTAInstitucionalhttp://repositorio.inta.gob.ar/Organismo científico-tecnológicoNo correspondehttp://repositorio.inta.gob.ar/oai/requesttripaldi.nicolas@inta.gob.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:l2025-10-16 09:31:19.666INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuariafalse
dc.title.none.fl_str_mv Congenital hypovitaminosis A in dairy cattle
title Congenital hypovitaminosis A in dairy cattle
spellingShingle Congenital hypovitaminosis A in dairy cattle
Sosa, Emiliano
Ceguera
Ternero
Deficiencia de Vitaminas
Ganado de Leche
Blindness
Calves
Vitamin Deficiencies
Metaplasia
Dairy Cattle
title_short Congenital hypovitaminosis A in dairy cattle
title_full Congenital hypovitaminosis A in dairy cattle
title_fullStr Congenital hypovitaminosis A in dairy cattle
title_full_unstemmed Congenital hypovitaminosis A in dairy cattle
title_sort Congenital hypovitaminosis A in dairy cattle
dc.creator.none.fl_str_mv Sosa, Emiliano
Morrell, Eleonora Lidia
Llada, Ignacio Mariano
Odriozola, Ernesto Raul
Canton, German Jose
author Sosa, Emiliano
author_facet Sosa, Emiliano
Morrell, Eleonora Lidia
Llada, Ignacio Mariano
Odriozola, Ernesto Raul
Canton, German Jose
author_role author
author2 Morrell, Eleonora Lidia
Llada, Ignacio Mariano
Odriozola, Ernesto Raul
Canton, German Jose
author2_role author
author
author
author
dc.subject.none.fl_str_mv Ceguera
Ternero
Deficiencia de Vitaminas
Ganado de Leche
Blindness
Calves
Vitamin Deficiencies
Metaplasia
Dairy Cattle
topic Ceguera
Ternero
Deficiencia de Vitaminas
Ganado de Leche
Blindness
Calves
Vitamin Deficiencies
Metaplasia
Dairy Cattle
dc.description.none.fl_txt_mv Hypovitaminosis A negatively impacts the health of ruminants feeding on low-fresh forage diets for long periods of time. Although this disease is characterised by different clinical presentations, its congenital form is underreported. Here, we describe an outbreak of vitamin A deficiency that affected 30% of calves born in a dairy heifer herd. At birth, the affected animals showed weakness, ataxia, mydriasis, bluish coloration of the tapetum lacidum and blindness as the main clinical signs. The gross pathological findings at postmortem examination revealed cerebellar herniation, flattened gyri and narrowed sulci of the cerebral cortex in an affected calf. Histopathology showed squamous metaplasia of the efferent ducts in the parotid gland and hyperkeratosis of the ruminal mucosa. In addition, the plasma levels of vitamin A in the heifers and calves were below the reference values. These results confirmed the first reported case of congenital hypovitaminosis A in cattle in Argentina.
EEA Balcarce
Fil: Sosa, Emiliano. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina.
Fil: Sosa, Emiliano. Universidad Nacional de La Pampa. Facultad de Ciencias Veterinarias; Argentina.
Fil: Morrell, Eleonora L. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina.
Fil: Llada, Ignacio. University of Georgia. Department of Physiology and Pharmacology. Interdisciplinary Toxicology Program; Estados Unidos.
Fil: Odriozola, Ernesto Raúl. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina.
Fil: Cantón Germán José. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina.
description Hypovitaminosis A negatively impacts the health of ruminants feeding on low-fresh forage diets for long periods of time. Although this disease is characterised by different clinical presentations, its congenital form is underreported. Here, we describe an outbreak of vitamin A deficiency that affected 30% of calves born in a dairy heifer herd. At birth, the affected animals showed weakness, ataxia, mydriasis, bluish coloration of the tapetum lacidum and blindness as the main clinical signs. The gross pathological findings at postmortem examination revealed cerebellar herniation, flattened gyri and narrowed sulci of the cerebral cortex in an affected calf. Histopathology showed squamous metaplasia of the efferent ducts in the parotid gland and hyperkeratosis of the ruminal mucosa. In addition, the plasma levels of vitamin A in the heifers and calves were below the reference values. These results confirmed the first reported case of congenital hypovitaminosis A in cattle in Argentina.
publishDate 2023
dc.date.none.fl_str_mv 2023-10-09T15:55:10Z
2023-10-09T15:55:10Z
2023-10-03
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12123/15484
https://bvajournals.onlinelibrary.wiley.com/doi/10.1002/vrc2.744
2052-6121
https://doi.org/10.1002/vrc2.744
url http://hdl.handle.net/20.500.12123/15484
https://bvajournals.onlinelibrary.wiley.com/doi/10.1002/vrc2.744
https://doi.org/10.1002/vrc2.744
identifier_str_mv 2052-6121
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repograntAgreement/INTA/2019-RIST-E5-I111-001, Laboratorios de Diagnóstico Veterinario
dc.rights.none.fl_str_mv info:eu-repo/semantics/restrictedAccess
http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv restrictedAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv British Veterinary Association
publisher.none.fl_str_mv British Veterinary Association
dc.source.none.fl_str_mv Veterinary Record Case Reports : e744 (2023)
reponame:INTA Digital (INTA)
instname:Instituto Nacional de Tecnología Agropecuaria
reponame_str INTA Digital (INTA)
collection INTA Digital (INTA)
instname_str Instituto Nacional de Tecnología Agropecuaria
repository.name.fl_str_mv INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuaria
repository.mail.fl_str_mv tripaldi.nicolas@inta.gob.ar
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