Resistance of the cattle tick Rhipicephalus (Boophilus) microplus to ivermectin in Argentina

Autores
Torrents, Jorgelina; Sarli, Macarena; Rossner, Maria Victoria; Toffaletti, Jose Rodolfo; Morel, Nicolas; Martinez, Norberto Claudio; Webster, Anelise; Mangold, Atilio Jose; Guglielmone, Alberto; Nava, Santiago
Año de publicación
2020
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Resistance to ivermectin in populations of the cattle tick Rhipicephalus microplus in Argentina was diagnosed in this work. The in vitro larval immersion test (LIT) was used to determine quantitatively the levels of resistance to ivermectin in different populations of R. microplus. Additionally, field trials to control natural infestations of R. microplus on cattle with a commercial formulation of ivermectin 3.15% were carried and jointly analyzed with the in vitro assays. The phenotypic response of the populations analyzed was not uniform. Five of them were classified as susceptible, four populations as resistant, and one in the category “incipient resistance”. Regarding the field trials, the therapeutic efficacy in a population classified with LIT as susceptible achieved values higher than 94% two weeks after treatment, and no reproductively viable females were observed after the second day post-treatment. Conversely, the values of efficacy percentage in a population (named as “San Martín”) classified with LIT in the category “incipient resistance” never exceeded the 70.8%, and engorged females were collected in practically all counts. The population “San Martín” was classified in the category “incipient resistant” with LIT analysis, but the field trial unambiguously shows that this tick population is resistant. The comparison of the results obtained with LIT in vitro assays and through field trials shows that biased estimations of resistance levels may occur when resistance ratios (RR) values are ≤2, and additional field efficacy trials could be needed to know with precision the status of the tick populations evaluated.
EEA Rafaela
Fil: Torrents, Jorgelina. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias; Argentina
Fil: Sarli, Macarena. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina.
Fil: Rossner, Maria Victoria. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Colonia Benitez; Argentina
Fil: Toffaletti, Jose Rodolfo. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria El Colorado; Argentina
Fil: Morel, Nicolas. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina
Fil: Martinez, Norberto Claudio. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Reconquista. Agencia De Extensión Rural Garabato; Argentina
Fil: Webster, Anelise. Instituto de Pesquisas Veterinárias Desidério Finamor; Brasil
Fil: Mangold, Atilio Jose. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina.
Fil: Guglielmone, Alberto. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina
Fil: Nava, Santiago. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fuente
Research in Veterinary Science 132 : 332-337 (October 2020)
Materia
Ganado Bovino
Rhipicephalus
Plagas de Animales
Control de Plagas
Ivermectina
Resistencia a los Acaricidas
Argentina
Cattle
Pests of Animals
Pest Control
Ivermectin
Resistance to Acaricides
Garrapatas
Rhipicephalus (Boophilus) microplus
Nivel de accesibilidad
acceso restringido
Condiciones de uso
Repositorio
INTA Digital (INTA)
Institución
Instituto Nacional de Tecnología Agropecuaria
OAI Identificador
oai:localhost:20.500.12123/7736
Acceder
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oai_identifier_str oai:localhost:20.500.12123/7736
network_acronym_str INTADig
repository_id_str l
network_name_str INTA Digital (INTA)
spelling Resistance of the cattle tick Rhipicephalus (Boophilus) microplus to ivermectin in ArgentinaTorrents, JorgelinaSarli, MacarenaRossner, Maria VictoriaToffaletti, Jose RodolfoMorel, NicolasMartinez, Norberto ClaudioWebster, AneliseMangold, Atilio JoseGuglielmone, AlbertoNava, SantiagoGanado BovinoRhipicephalusPlagas de AnimalesControl de PlagasIvermectinaResistencia a los AcaricidasArgentinaCattlePests of AnimalsPest ControlIvermectinResistance to AcaricidesGarrapatasRhipicephalus (Boophilus) microplusResistance to ivermectin in populations of the cattle tick Rhipicephalus microplus in Argentina was diagnosed in this work. The in vitro larval immersion test (LIT) was used to determine quantitatively the levels of resistance to ivermectin in different populations of R. microplus. Additionally, field trials to control natural infestations of R. microplus on cattle with a commercial formulation of ivermectin 3.15% were carried and jointly analyzed with the in vitro assays. The phenotypic response of the populations analyzed was not uniform. Five of them were classified as susceptible, four populations as resistant, and one in the category “incipient resistance”. Regarding the field trials, the therapeutic efficacy in a population classified with LIT as susceptible achieved values higher than 94% two weeks after treatment, and no reproductively viable females were observed after the second day post-treatment. Conversely, the values of efficacy percentage in a population (named as “San Martín”) classified with LIT in the category “incipient resistance” never exceeded the 70.8%, and engorged females were collected in practically all counts. The population “San Martín” was classified in the category “incipient resistant” with LIT analysis, but the field trial unambiguously shows that this tick population is resistant. The comparison of the results obtained with LIT in vitro assays and through field trials shows that biased estimations of resistance levels may occur when resistance ratios (RR) values are ≤2, and additional field efficacy trials could be needed to know with precision the status of the tick populations evaluated.EEA RafaelaFil: Torrents, Jorgelina. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias; ArgentinaFil: Sarli, Macarena. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina.Fil: Rossner, Maria Victoria. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Colonia Benitez; ArgentinaFil: Toffaletti, Jose Rodolfo. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria El Colorado; ArgentinaFil: Morel, Nicolas. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; ArgentinaFil: Martinez, Norberto Claudio. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Reconquista. Agencia De Extensión Rural Garabato; ArgentinaFil: Webster, Anelise. Instituto de Pesquisas Veterinárias Desidério Finamor; BrasilFil: Mangold, Atilio Jose. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina.Fil: Guglielmone, Alberto. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; ArgentinaFil: Nava, Santiago. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaElsevier2020-08-19T12:28:21Z2020-08-19T12:28:21Z2020info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://hdl.handle.net/20.500.12123/7736https://www.sciencedirect.com/science/article/abs/pii/S00345288203092550034-5288https://doi.org/10.1016/j.rvsc.2020.07.012Research in Veterinary Science 132 : 332-337 (October 2020)reponame:INTA Digital (INTA)instname:Instituto Nacional de Tecnología Agropecuariaenginfo:eu-repo/semantics/restrictedAccess2025-10-16T09:29:52Zoai:localhost:20.500.12123/7736instacron:INTAInstitucionalhttp://repositorio.inta.gob.ar/Organismo científico-tecnológicoNo correspondehttp://repositorio.inta.gob.ar/oai/requesttripaldi.nicolas@inta.gob.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:l2025-10-16 09:29:52.947INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuariafalse
dc.title.none.fl_str_mv Resistance of the cattle tick Rhipicephalus (Boophilus) microplus to ivermectin in Argentina
title Resistance of the cattle tick Rhipicephalus (Boophilus) microplus to ivermectin in Argentina
spellingShingle Resistance of the cattle tick Rhipicephalus (Boophilus) microplus to ivermectin in Argentina
Torrents, Jorgelina
Ganado Bovino
Rhipicephalus
Plagas de Animales
Control de Plagas
Ivermectina
Resistencia a los Acaricidas
Argentina
Cattle
Pests of Animals
Pest Control
Ivermectin
Resistance to Acaricides
Garrapatas
Rhipicephalus (Boophilus) microplus
title_short Resistance of the cattle tick Rhipicephalus (Boophilus) microplus to ivermectin in Argentina
title_full Resistance of the cattle tick Rhipicephalus (Boophilus) microplus to ivermectin in Argentina
title_fullStr Resistance of the cattle tick Rhipicephalus (Boophilus) microplus to ivermectin in Argentina
title_full_unstemmed Resistance of the cattle tick Rhipicephalus (Boophilus) microplus to ivermectin in Argentina
title_sort Resistance of the cattle tick Rhipicephalus (Boophilus) microplus to ivermectin in Argentina
dc.creator.none.fl_str_mv Torrents, Jorgelina
Sarli, Macarena
Rossner, Maria Victoria
Toffaletti, Jose Rodolfo
Morel, Nicolas
Martinez, Norberto Claudio
Webster, Anelise
Mangold, Atilio Jose
Guglielmone, Alberto
Nava, Santiago
author Torrents, Jorgelina
author_facet Torrents, Jorgelina
Sarli, Macarena
Rossner, Maria Victoria
Toffaletti, Jose Rodolfo
Morel, Nicolas
Martinez, Norberto Claudio
Webster, Anelise
Mangold, Atilio Jose
Guglielmone, Alberto
Nava, Santiago
author_role author
author2 Sarli, Macarena
Rossner, Maria Victoria
Toffaletti, Jose Rodolfo
Morel, Nicolas
Martinez, Norberto Claudio
Webster, Anelise
Mangold, Atilio Jose
Guglielmone, Alberto
Nava, Santiago
author2_role author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Ganado Bovino
Rhipicephalus
Plagas de Animales
Control de Plagas
Ivermectina
Resistencia a los Acaricidas
Argentina
Cattle
Pests of Animals
Pest Control
Ivermectin
Resistance to Acaricides
Garrapatas
Rhipicephalus (Boophilus) microplus
topic Ganado Bovino
Rhipicephalus
Plagas de Animales
Control de Plagas
Ivermectina
Resistencia a los Acaricidas
Argentina
Cattle
Pests of Animals
Pest Control
Ivermectin
Resistance to Acaricides
Garrapatas
Rhipicephalus (Boophilus) microplus
dc.description.none.fl_txt_mv Resistance to ivermectin in populations of the cattle tick Rhipicephalus microplus in Argentina was diagnosed in this work. The in vitro larval immersion test (LIT) was used to determine quantitatively the levels of resistance to ivermectin in different populations of R. microplus. Additionally, field trials to control natural infestations of R. microplus on cattle with a commercial formulation of ivermectin 3.15% were carried and jointly analyzed with the in vitro assays. The phenotypic response of the populations analyzed was not uniform. Five of them were classified as susceptible, four populations as resistant, and one in the category “incipient resistance”. Regarding the field trials, the therapeutic efficacy in a population classified with LIT as susceptible achieved values higher than 94% two weeks after treatment, and no reproductively viable females were observed after the second day post-treatment. Conversely, the values of efficacy percentage in a population (named as “San Martín”) classified with LIT in the category “incipient resistance” never exceeded the 70.8%, and engorged females were collected in practically all counts. The population “San Martín” was classified in the category “incipient resistant” with LIT analysis, but the field trial unambiguously shows that this tick population is resistant. The comparison of the results obtained with LIT in vitro assays and through field trials shows that biased estimations of resistance levels may occur when resistance ratios (RR) values are ≤2, and additional field efficacy trials could be needed to know with precision the status of the tick populations evaluated.
EEA Rafaela
Fil: Torrents, Jorgelina. Universidad Nacional del Litoral. Facultad de Ciencias Veterinarias; Argentina
Fil: Sarli, Macarena. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina.
Fil: Rossner, Maria Victoria. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Colonia Benitez; Argentina
Fil: Toffaletti, Jose Rodolfo. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria El Colorado; Argentina
Fil: Morel, Nicolas. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina
Fil: Martinez, Norberto Claudio. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Reconquista. Agencia De Extensión Rural Garabato; Argentina
Fil: Webster, Anelise. Instituto de Pesquisas Veterinárias Desidério Finamor; Brasil
Fil: Mangold, Atilio Jose. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina.
Fil: Guglielmone, Alberto. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina
Fil: Nava, Santiago. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
description Resistance to ivermectin in populations of the cattle tick Rhipicephalus microplus in Argentina was diagnosed in this work. The in vitro larval immersion test (LIT) was used to determine quantitatively the levels of resistance to ivermectin in different populations of R. microplus. Additionally, field trials to control natural infestations of R. microplus on cattle with a commercial formulation of ivermectin 3.15% were carried and jointly analyzed with the in vitro assays. The phenotypic response of the populations analyzed was not uniform. Five of them were classified as susceptible, four populations as resistant, and one in the category “incipient resistance”. Regarding the field trials, the therapeutic efficacy in a population classified with LIT as susceptible achieved values higher than 94% two weeks after treatment, and no reproductively viable females were observed after the second day post-treatment. Conversely, the values of efficacy percentage in a population (named as “San Martín”) classified with LIT in the category “incipient resistance” never exceeded the 70.8%, and engorged females were collected in practically all counts. The population “San Martín” was classified in the category “incipient resistant” with LIT analysis, but the field trial unambiguously shows that this tick population is resistant. The comparison of the results obtained with LIT in vitro assays and through field trials shows that biased estimations of resistance levels may occur when resistance ratios (RR) values are ≤2, and additional field efficacy trials could be needed to know with precision the status of the tick populations evaluated.
publishDate 2020
dc.date.none.fl_str_mv 2020-08-19T12:28:21Z
2020-08-19T12:28:21Z
2020
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12123/7736
https://www.sciencedirect.com/science/article/abs/pii/S0034528820309255
0034-5288
https://doi.org/10.1016/j.rvsc.2020.07.012
url http://hdl.handle.net/20.500.12123/7736
https://www.sciencedirect.com/science/article/abs/pii/S0034528820309255
https://doi.org/10.1016/j.rvsc.2020.07.012
identifier_str_mv 0034-5288
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/restrictedAccess
eu_rights_str_mv restrictedAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv Research in Veterinary Science 132 : 332-337 (October 2020)
reponame:INTA Digital (INTA)
instname:Instituto Nacional de Tecnología Agropecuaria
reponame_str INTA Digital (INTA)
collection INTA Digital (INTA)
instname_str Instituto Nacional de Tecnología Agropecuaria
repository.name.fl_str_mv INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuaria
repository.mail.fl_str_mv tripaldi.nicolas@inta.gob.ar
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score 12.6140175

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