Cost-effectiveness of COVID-19 vaccination in Latin America and the Caribbean: An analysis in Argentina, Brazil, Chile, Colombia, Costa Rica, Mexico, and Peru
- Autores
- Augustovski, Federico Ariel; Bardach, Ariel Esteban; Santoro, Adrián; Rodriguez Cairoli, Federico; López Osornio, Alejandro; Argento, Fernando; Havela, Maissa; Blumenfeld, Alejandro; Ballivian, Jamile; Solioz, Germán; Capula, Analía; López, Analía; Cejas, Cintia; Savedoff, William; Palacios, Alfredo; Rubinstein, Adolfo Luis; Pichón-Riviere, Andres
- Año de publicación
- 2023
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Objective: Our study analyzes the cost-effectiveness of the COVID-19 vaccination campaigns in Argentina, Brazil, Chile, Colombia, Costa Rica, Mexico, and Peru. Methods: Using a previously published SVEIR model, we analyzed the impact of a vaccination campaign (2021) from a national healthcare perspective. The primary outcomes were quality adjusted life years (QALYs) lost and total costs. Other outcomes included COVID-19 cases, hospitalizations, deaths, and life years. We applied a discount rate of 3% for health outcomes. We modeled a realistic vaccination campaign in each country (the realistic country-specific campaign). Additionally, we assessed a standard campaign (similar, “typical“ for all countries), and an optimized campaign (similar in all countries with higher but plausible population coverage). One-way deterministic sensitivity analyses were performed. Findings: Vaccination was health improving as well as cost-saving in almost all countries and scenarios. Our analysis shows that vaccination in this group of countries prevented 573,141 deaths (508,826 standard; 685,442 optimized) and gained 5.07 million QALYs (4.53 standard; 6.03 optimized). Despite the incremental costs of vaccination campaigns, they had a total net cost saving to the health system of US$16.29 billion (US$16.47 standard; US$18.58 optimized). The realistic (base case) vaccination campaign in Chile was the only scenario, which was not cost saving, but it was still highly cost-effective with an ICER of US$22 per QALY gained. Main findings were robust in the sensitivity analyses. Interpretation: The COVID-19 vaccination campaign in seven Latin American and Caribbean countries -that comprise nearly 80% of the region- was beneficial for population health and was also cost-saving or highly cost-effective.
Fil: Augustovski, Federico Ariel. Instituto de Efectividad Clínica y Sanitaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; Argentina
Fil: Bardach, Ariel Esteban. Instituto de Efectividad Clínica y Sanitaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; Argentina
Fil: Santoro, Adrián. Instituto de Efectividad Clínica y Sanitaria; Argentina
Fil: Rodriguez Cairoli, Federico. Instituto de Efectividad Clínica y Sanitaria; Argentina
Fil: López Osornio, Alejandro. Instituto de Efectividad Clínica y Sanitaria; Argentina
Fil: Argento, Fernando. Instituto de Efectividad Clínica y Sanitaria; Argentina
Fil: Havela, Maissa. Instituto de Efectividad Clínica y Sanitaria; Argentina
Fil: Blumenfeld, Alejandro. Instituto de Efectividad Clínica y Sanitaria; Argentina
Fil: Ballivian, Jamile. Instituto de Efectividad Clínica y Sanitaria; Argentina
Fil: Solioz, Germán. Instituto de Efectividad Clínica y Sanitaria; Argentina
Fil: Capula, Analía. Instituto de Efectividad Clínica y Sanitaria; Argentina
Fil: López, Analía. Instituto de Efectividad Clínica y Sanitaria; Argentina
Fil: Cejas, Cintia. Instituto de Efectividad Clínica y Sanitaria; Argentina
Fil: Savedoff, William. Social Insight; Estados Unidos
Fil: Palacios, Alfredo. Instituto de Efectividad Clínica y Sanitaria; Argentina
Fil: Rubinstein, Adolfo Luis. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; Argentina. Instituto de Efectividad Clínica y Sanitaria; Argentina
Fil: Pichón-Riviere, Andres. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; Argentina. Instituto de Efectividad Clínica y Sanitaria; Argentina - Materia
-
COVID-19
Latin America and the Caribbean
Cost-effectiveness - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by/2.5/ar/
- Repositorio
.jpg)
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/229143
Ver los metadatos del registro completo
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Cost-effectiveness of COVID-19 vaccination in Latin America and the Caribbean: An analysis in Argentina, Brazil, Chile, Colombia, Costa Rica, Mexico, and PeruAugustovski, Federico ArielBardach, Ariel EstebanSantoro, AdriánRodriguez Cairoli, FedericoLópez Osornio, AlejandroArgento, FernandoHavela, MaissaBlumenfeld, AlejandroBallivian, JamileSolioz, GermánCapula, AnalíaLópez, AnalíaCejas, CintiaSavedoff, WilliamPalacios, AlfredoRubinstein, Adolfo LuisPichón-Riviere, AndresCOVID-19Latin America and the CaribbeanCost-effectivenesshttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Objective: Our study analyzes the cost-effectiveness of the COVID-19 vaccination campaigns in Argentina, Brazil, Chile, Colombia, Costa Rica, Mexico, and Peru. Methods: Using a previously published SVEIR model, we analyzed the impact of a vaccination campaign (2021) from a national healthcare perspective. The primary outcomes were quality adjusted life years (QALYs) lost and total costs. Other outcomes included COVID-19 cases, hospitalizations, deaths, and life years. We applied a discount rate of 3% for health outcomes. We modeled a realistic vaccination campaign in each country (the realistic country-specific campaign). Additionally, we assessed a standard campaign (similar, “typical“ for all countries), and an optimized campaign (similar in all countries with higher but plausible population coverage). One-way deterministic sensitivity analyses were performed. Findings: Vaccination was health improving as well as cost-saving in almost all countries and scenarios. Our analysis shows that vaccination in this group of countries prevented 573,141 deaths (508,826 standard; 685,442 optimized) and gained 5.07 million QALYs (4.53 standard; 6.03 optimized). Despite the incremental costs of vaccination campaigns, they had a total net cost saving to the health system of US$16.29 billion (US$16.47 standard; US$18.58 optimized). The realistic (base case) vaccination campaign in Chile was the only scenario, which was not cost saving, but it was still highly cost-effective with an ICER of US$22 per QALY gained. Main findings were robust in the sensitivity analyses. Interpretation: The COVID-19 vaccination campaign in seven Latin American and Caribbean countries -that comprise nearly 80% of the region- was beneficial for population health and was also cost-saving or highly cost-effective.Fil: Augustovski, Federico Ariel. Instituto de Efectividad Clínica y Sanitaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; ArgentinaFil: Bardach, Ariel Esteban. Instituto de Efectividad Clínica y Sanitaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; ArgentinaFil: Santoro, Adrián. Instituto de Efectividad Clínica y Sanitaria; ArgentinaFil: Rodriguez Cairoli, Federico. Instituto de Efectividad Clínica y Sanitaria; ArgentinaFil: López Osornio, Alejandro. Instituto de Efectividad Clínica y Sanitaria; ArgentinaFil: Argento, Fernando. Instituto de Efectividad Clínica y Sanitaria; ArgentinaFil: Havela, Maissa. Instituto de Efectividad Clínica y Sanitaria; ArgentinaFil: Blumenfeld, Alejandro. Instituto de Efectividad Clínica y Sanitaria; ArgentinaFil: Ballivian, Jamile. Instituto de Efectividad Clínica y Sanitaria; ArgentinaFil: Solioz, Germán. Instituto de Efectividad Clínica y Sanitaria; ArgentinaFil: Capula, Analía. Instituto de Efectividad Clínica y Sanitaria; ArgentinaFil: López, Analía. Instituto de Efectividad Clínica y Sanitaria; ArgentinaFil: Cejas, Cintia. Instituto de Efectividad Clínica y Sanitaria; ArgentinaFil: Savedoff, William. Social Insight; Estados UnidosFil: Palacios, Alfredo. Instituto de Efectividad Clínica y Sanitaria; ArgentinaFil: Rubinstein, Adolfo Luis. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; Argentina. Instituto de Efectividad Clínica y Sanitaria; ArgentinaFil: Pichón-Riviere, Andres. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; Argentina. Instituto de Efectividad Clínica y Sanitaria; ArgentinaBioMed Central2023-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/229143Augustovski, Federico Ariel; Bardach, Ariel Esteban; Santoro, Adrián; Rodriguez Cairoli, Federico; López Osornio, Alejandro; et al.; Cost-effectiveness of COVID-19 vaccination in Latin America and the Caribbean: An analysis in Argentina, Brazil, Chile, Colombia, Costa Rica, Mexico, and Peru; BioMed Central; Cost Effectiveness and Resource Allocation; 21; 1; 12-2023; 1-131478-7547CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1186/s12962-023-00430-2info:eu-repo/semantics/altIdentifier/url/https://resource-allocation.biomedcentral.com/articles/10.1186/s12962-023-00430-2info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:13:09Zoai:ri.conicet.gov.ar:11336/229143instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:13:09.911CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
| dc.title.none.fl_str_mv |
Cost-effectiveness of COVID-19 vaccination in Latin America and the Caribbean: An analysis in Argentina, Brazil, Chile, Colombia, Costa Rica, Mexico, and Peru |
| title |
Cost-effectiveness of COVID-19 vaccination in Latin America and the Caribbean: An analysis in Argentina, Brazil, Chile, Colombia, Costa Rica, Mexico, and Peru |
| spellingShingle |
Cost-effectiveness of COVID-19 vaccination in Latin America and the Caribbean: An analysis in Argentina, Brazil, Chile, Colombia, Costa Rica, Mexico, and Peru Augustovski, Federico Ariel COVID-19 Latin America and the Caribbean Cost-effectiveness |
| title_short |
Cost-effectiveness of COVID-19 vaccination in Latin America and the Caribbean: An analysis in Argentina, Brazil, Chile, Colombia, Costa Rica, Mexico, and Peru |
| title_full |
Cost-effectiveness of COVID-19 vaccination in Latin America and the Caribbean: An analysis in Argentina, Brazil, Chile, Colombia, Costa Rica, Mexico, and Peru |
| title_fullStr |
Cost-effectiveness of COVID-19 vaccination in Latin America and the Caribbean: An analysis in Argentina, Brazil, Chile, Colombia, Costa Rica, Mexico, and Peru |
| title_full_unstemmed |
Cost-effectiveness of COVID-19 vaccination in Latin America and the Caribbean: An analysis in Argentina, Brazil, Chile, Colombia, Costa Rica, Mexico, and Peru |
| title_sort |
Cost-effectiveness of COVID-19 vaccination in Latin America and the Caribbean: An analysis in Argentina, Brazil, Chile, Colombia, Costa Rica, Mexico, and Peru |
| dc.creator.none.fl_str_mv |
Augustovski, Federico Ariel Bardach, Ariel Esteban Santoro, Adrián Rodriguez Cairoli, Federico López Osornio, Alejandro Argento, Fernando Havela, Maissa Blumenfeld, Alejandro Ballivian, Jamile Solioz, Germán Capula, Analía López, Analía Cejas, Cintia Savedoff, William Palacios, Alfredo Rubinstein, Adolfo Luis Pichón-Riviere, Andres |
| author |
Augustovski, Federico Ariel |
| author_facet |
Augustovski, Federico Ariel Bardach, Ariel Esteban Santoro, Adrián Rodriguez Cairoli, Federico López Osornio, Alejandro Argento, Fernando Havela, Maissa Blumenfeld, Alejandro Ballivian, Jamile Solioz, Germán Capula, Analía López, Analía Cejas, Cintia Savedoff, William Palacios, Alfredo Rubinstein, Adolfo Luis Pichón-Riviere, Andres |
| author_role |
author |
| author2 |
Bardach, Ariel Esteban Santoro, Adrián Rodriguez Cairoli, Federico López Osornio, Alejandro Argento, Fernando Havela, Maissa Blumenfeld, Alejandro Ballivian, Jamile Solioz, Germán Capula, Analía López, Analía Cejas, Cintia Savedoff, William Palacios, Alfredo Rubinstein, Adolfo Luis Pichón-Riviere, Andres |
| author2_role |
author author author author author author author author author author author author author author author author |
| dc.subject.none.fl_str_mv |
COVID-19 Latin America and the Caribbean Cost-effectiveness |
| topic |
COVID-19 Latin America and the Caribbean Cost-effectiveness |
| purl_subject.fl_str_mv |
https://purl.org/becyt/ford/3.3 https://purl.org/becyt/ford/3 |
| dc.description.none.fl_txt_mv |
Objective: Our study analyzes the cost-effectiveness of the COVID-19 vaccination campaigns in Argentina, Brazil, Chile, Colombia, Costa Rica, Mexico, and Peru. Methods: Using a previously published SVEIR model, we analyzed the impact of a vaccination campaign (2021) from a national healthcare perspective. The primary outcomes were quality adjusted life years (QALYs) lost and total costs. Other outcomes included COVID-19 cases, hospitalizations, deaths, and life years. We applied a discount rate of 3% for health outcomes. We modeled a realistic vaccination campaign in each country (the realistic country-specific campaign). Additionally, we assessed a standard campaign (similar, “typical“ for all countries), and an optimized campaign (similar in all countries with higher but plausible population coverage). One-way deterministic sensitivity analyses were performed. Findings: Vaccination was health improving as well as cost-saving in almost all countries and scenarios. Our analysis shows that vaccination in this group of countries prevented 573,141 deaths (508,826 standard; 685,442 optimized) and gained 5.07 million QALYs (4.53 standard; 6.03 optimized). Despite the incremental costs of vaccination campaigns, they had a total net cost saving to the health system of US$16.29 billion (US$16.47 standard; US$18.58 optimized). The realistic (base case) vaccination campaign in Chile was the only scenario, which was not cost saving, but it was still highly cost-effective with an ICER of US$22 per QALY gained. Main findings were robust in the sensitivity analyses. Interpretation: The COVID-19 vaccination campaign in seven Latin American and Caribbean countries -that comprise nearly 80% of the region- was beneficial for population health and was also cost-saving or highly cost-effective. Fil: Augustovski, Federico Ariel. Instituto de Efectividad Clínica y Sanitaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; Argentina Fil: Bardach, Ariel Esteban. Instituto de Efectividad Clínica y Sanitaria; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; Argentina Fil: Santoro, Adrián. Instituto de Efectividad Clínica y Sanitaria; Argentina Fil: Rodriguez Cairoli, Federico. Instituto de Efectividad Clínica y Sanitaria; Argentina Fil: López Osornio, Alejandro. Instituto de Efectividad Clínica y Sanitaria; Argentina Fil: Argento, Fernando. Instituto de Efectividad Clínica y Sanitaria; Argentina Fil: Havela, Maissa. Instituto de Efectividad Clínica y Sanitaria; Argentina Fil: Blumenfeld, Alejandro. Instituto de Efectividad Clínica y Sanitaria; Argentina Fil: Ballivian, Jamile. Instituto de Efectividad Clínica y Sanitaria; Argentina Fil: Solioz, Germán. Instituto de Efectividad Clínica y Sanitaria; Argentina Fil: Capula, Analía. Instituto de Efectividad Clínica y Sanitaria; Argentina Fil: López, Analía. Instituto de Efectividad Clínica y Sanitaria; Argentina Fil: Cejas, Cintia. Instituto de Efectividad Clínica y Sanitaria; Argentina Fil: Savedoff, William. Social Insight; Estados Unidos Fil: Palacios, Alfredo. Instituto de Efectividad Clínica y Sanitaria; Argentina Fil: Rubinstein, Adolfo Luis. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; Argentina. Instituto de Efectividad Clínica y Sanitaria; Argentina Fil: Pichón-Riviere, Andres. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; Argentina. Instituto de Efectividad Clínica y Sanitaria; Argentina |
| description |
Objective: Our study analyzes the cost-effectiveness of the COVID-19 vaccination campaigns in Argentina, Brazil, Chile, Colombia, Costa Rica, Mexico, and Peru. Methods: Using a previously published SVEIR model, we analyzed the impact of a vaccination campaign (2021) from a national healthcare perspective. The primary outcomes were quality adjusted life years (QALYs) lost and total costs. Other outcomes included COVID-19 cases, hospitalizations, deaths, and life years. We applied a discount rate of 3% for health outcomes. We modeled a realistic vaccination campaign in each country (the realistic country-specific campaign). Additionally, we assessed a standard campaign (similar, “typical“ for all countries), and an optimized campaign (similar in all countries with higher but plausible population coverage). One-way deterministic sensitivity analyses were performed. Findings: Vaccination was health improving as well as cost-saving in almost all countries and scenarios. Our analysis shows that vaccination in this group of countries prevented 573,141 deaths (508,826 standard; 685,442 optimized) and gained 5.07 million QALYs (4.53 standard; 6.03 optimized). Despite the incremental costs of vaccination campaigns, they had a total net cost saving to the health system of US$16.29 billion (US$16.47 standard; US$18.58 optimized). The realistic (base case) vaccination campaign in Chile was the only scenario, which was not cost saving, but it was still highly cost-effective with an ICER of US$22 per QALY gained. Main findings were robust in the sensitivity analyses. Interpretation: The COVID-19 vaccination campaign in seven Latin American and Caribbean countries -that comprise nearly 80% of the region- was beneficial for population health and was also cost-saving or highly cost-effective. |
| publishDate |
2023 |
| dc.date.none.fl_str_mv |
2023-12 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
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article |
| status_str |
publishedVersion |
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http://hdl.handle.net/11336/229143 Augustovski, Federico Ariel; Bardach, Ariel Esteban; Santoro, Adrián; Rodriguez Cairoli, Federico; López Osornio, Alejandro; et al.; Cost-effectiveness of COVID-19 vaccination in Latin America and the Caribbean: An analysis in Argentina, Brazil, Chile, Colombia, Costa Rica, Mexico, and Peru; BioMed Central; Cost Effectiveness and Resource Allocation; 21; 1; 12-2023; 1-13 1478-7547 CONICET Digital CONICET |
| url |
http://hdl.handle.net/11336/229143 |
| identifier_str_mv |
Augustovski, Federico Ariel; Bardach, Ariel Esteban; Santoro, Adrián; Rodriguez Cairoli, Federico; López Osornio, Alejandro; et al.; Cost-effectiveness of COVID-19 vaccination in Latin America and the Caribbean: An analysis in Argentina, Brazil, Chile, Colombia, Costa Rica, Mexico, and Peru; BioMed Central; Cost Effectiveness and Resource Allocation; 21; 1; 12-2023; 1-13 1478-7547 CONICET Digital CONICET |
| dc.language.none.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/doi/10.1186/s12962-023-00430-2 info:eu-repo/semantics/altIdentifier/url/https://resource-allocation.biomedcentral.com/articles/10.1186/s12962-023-00430-2 |
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info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/2.5/ar/ |
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openAccess |
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https://creativecommons.org/licenses/by/2.5/ar/ |
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application/pdf application/pdf application/pdf application/pdf application/pdf |
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BioMed Central |
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BioMed Central |
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CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
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dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
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