Layer-by-layer assembly of polymersomes and polyelectrolytes on planar surfaces and microsized colloidal particles

Autores
Coustet, Marcos Eduardo; Irigoyen, Joseba; Alonso Garcia, Teodoro; Murray, Richard A.; Romero, Gabriela; Cortizo, Maria Susana; Knoll, Wolfgang; Azzaroni, Omar; Moya, Sergio Eduardo
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Hybrid polyelectrolyte multilayer systems were fabricated on top of planar surfaces and colloidal particles via layer by layer (LbL) assembly of polystyrene sulphonate (PSS) and polybenzyl methacrylate-block-poly(dimethylamino)ethyl methacrylate (PBzMA-b-PDMAEMA) polymersomes. Polymersomes were prepared by self assembly of PBzMA-b-PDMAEMA copolymer, synthesised by group transfer polymerisation. Polymersomes display a diameter of 270 nm and a shell thickness of 11 nm. Assembly on planar surfaces was followed by means of the Quartz Crystal Microbalance with Dissipation (QCM-D) and Atomic Force Microscopy (AFM). Detailed information on the assembly mechanism and surface topology of the polymersome/polyelectrolyte films was thereby obtained. The assembly of polymersomes and PSS on top of silica particles of 500 nm in diameter was confirmed by ζ-potential measurements. Confocal laser scanning microscopy (CLSM), scanning electron microscopy (SEM) and transmission electron microscopy (TEM) revealed that polymersome/PSS coated silica particles increase in total diameter up to 3–5 μm. This hints toward the formation of densely packed polymersome layers. In addition, CLSM showed that polymersome/PSS films exhibit a high loading capacity that could potentially be used for encapsulation and delivery of diverse chemical species. These results provide an insight into the formation of multilayered films with compartmentalised hydrophilic/hydrophobic domains and may lead to the successful application of polymersomes in surface-engineered colloidal systems.
Fil: Coustet, Marcos Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas; Argentina
Fil: Irigoyen, Joseba. Centro de Investigación Cooperativa en Biomateriales. San Sebastián; España
Fil: Alonso Garcia, Teodoro. Centro de Investigación Cooperativa en Biomateriales. San Sebastián; España
Fil: Murray, Richard A.. Centro de Investigación Cooperativa en Biomateriales. San Sebastián; España
Fil: Romero, Gabriela. Centro de Investigación Cooperativa en Biomateriales. San Sebastián; España
Fil: Cortizo, Maria Susana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas; Argentina
Fil: Knoll, Wolfgang. Austrian Institute of Technology. Viena; Austria
Fil: Azzaroni, Omar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas; Argentina
Fil: Moya, Sergio Eduardo. Centro de Investigación Cooperativa en Biomateriales. San Sebastián; España
Materia
Layer-By-Layer Assembly
Colloidal Nanomaterials
Polymersomes
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/32272
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/32272
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Layer-by-layer assembly of polymersomes and polyelectrolytes on planar surfaces and microsized colloidal particlesCoustet, Marcos EduardoIrigoyen, JosebaAlonso Garcia, TeodoroMurray, Richard A.Romero, GabrielaCortizo, Maria SusanaKnoll, WolfgangAzzaroni, OmarMoya, Sergio EduardoLayer-By-Layer AssemblyColloidal NanomaterialsPolymersomeshttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1Hybrid polyelectrolyte multilayer systems were fabricated on top of planar surfaces and colloidal particles via layer by layer (LbL) assembly of polystyrene sulphonate (PSS) and polybenzyl methacrylate-block-poly(dimethylamino)ethyl methacrylate (PBzMA-b-PDMAEMA) polymersomes. Polymersomes were prepared by self assembly of PBzMA-b-PDMAEMA copolymer, synthesised by group transfer polymerisation. Polymersomes display a diameter of 270 nm and a shell thickness of 11 nm. Assembly on planar surfaces was followed by means of the Quartz Crystal Microbalance with Dissipation (QCM-D) and Atomic Force Microscopy (AFM). Detailed information on the assembly mechanism and surface topology of the polymersome/polyelectrolyte films was thereby obtained. The assembly of polymersomes and PSS on top of silica particles of 500 nm in diameter was confirmed by ζ-potential measurements. Confocal laser scanning microscopy (CLSM), scanning electron microscopy (SEM) and transmission electron microscopy (TEM) revealed that polymersome/PSS coated silica particles increase in total diameter up to 3–5 μm. This hints toward the formation of densely packed polymersome layers. In addition, CLSM showed that polymersome/PSS films exhibit a high loading capacity that could potentially be used for encapsulation and delivery of diverse chemical species. These results provide an insight into the formation of multilayered films with compartmentalised hydrophilic/hydrophobic domains and may lead to the successful application of polymersomes in surface-engineered colloidal systems.Fil: Coustet, Marcos Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas; ArgentinaFil: Irigoyen, Joseba. Centro de Investigación Cooperativa en Biomateriales. San Sebastián; EspañaFil: Alonso Garcia, Teodoro. Centro de Investigación Cooperativa en Biomateriales. San Sebastián; EspañaFil: Murray, Richard A.. Centro de Investigación Cooperativa en Biomateriales. San Sebastián; EspañaFil: Romero, Gabriela. Centro de Investigación Cooperativa en Biomateriales. San Sebastián; EspañaFil: Cortizo, Maria Susana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas; ArgentinaFil: Knoll, Wolfgang. Austrian Institute of Technology. Viena; AustriaFil: Azzaroni, Omar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas; ArgentinaFil: Moya, Sergio Eduardo. Centro de Investigación Cooperativa en Biomateriales. San Sebastián; EspañaAcademic Press Inc Elsevier Science2014-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/32272Alonso Garcia, Teodoro; Coustet, Marcos Eduardo; Azzaroni, Omar; Murray, Richard A.; Irigoyen, Joseba; Romero, Gabriela; et al.; Layer-by-layer assembly of polymersomes and polyelectrolytes on planar surfaces and microsized colloidal particles; Academic Press Inc Elsevier Science; Journal of Colloid and Interface Science; 421; 1-2014; 132-1400021-9797CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.jcis.2014.01.038info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0021979714000617info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:01:27Zoai:ri.conicet.gov.ar:11336/32272instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:01:27.584CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Layer-by-layer assembly of polymersomes and polyelectrolytes on planar surfaces and microsized colloidal particles
title Layer-by-layer assembly of polymersomes and polyelectrolytes on planar surfaces and microsized colloidal particles
spellingShingle Layer-by-layer assembly of polymersomes and polyelectrolytes on planar surfaces and microsized colloidal particles
Coustet, Marcos Eduardo
Layer-By-Layer Assembly
Colloidal Nanomaterials
Polymersomes
title_short Layer-by-layer assembly of polymersomes and polyelectrolytes on planar surfaces and microsized colloidal particles
title_full Layer-by-layer assembly of polymersomes and polyelectrolytes on planar surfaces and microsized colloidal particles
title_fullStr Layer-by-layer assembly of polymersomes and polyelectrolytes on planar surfaces and microsized colloidal particles
title_full_unstemmed Layer-by-layer assembly of polymersomes and polyelectrolytes on planar surfaces and microsized colloidal particles
title_sort Layer-by-layer assembly of polymersomes and polyelectrolytes on planar surfaces and microsized colloidal particles
dc.creator.none.fl_str_mv Coustet, Marcos Eduardo
Irigoyen, Joseba
Alonso Garcia, Teodoro
Murray, Richard A.
Romero, Gabriela
Cortizo, Maria Susana
Knoll, Wolfgang
Azzaroni, Omar
Moya, Sergio Eduardo
author Coustet, Marcos Eduardo
author_facet Coustet, Marcos Eduardo
Irigoyen, Joseba
Alonso Garcia, Teodoro
Murray, Richard A.
Romero, Gabriela
Cortizo, Maria Susana
Knoll, Wolfgang
Azzaroni, Omar
Moya, Sergio Eduardo
author_role author
author2 Irigoyen, Joseba
Alonso Garcia, Teodoro
Murray, Richard A.
Romero, Gabriela
Cortizo, Maria Susana
Knoll, Wolfgang
Azzaroni, Omar
Moya, Sergio Eduardo
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Layer-By-Layer Assembly
Colloidal Nanomaterials
Polymersomes
topic Layer-By-Layer Assembly
Colloidal Nanomaterials
Polymersomes
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Hybrid polyelectrolyte multilayer systems were fabricated on top of planar surfaces and colloidal particles via layer by layer (LbL) assembly of polystyrene sulphonate (PSS) and polybenzyl methacrylate-block-poly(dimethylamino)ethyl methacrylate (PBzMA-b-PDMAEMA) polymersomes. Polymersomes were prepared by self assembly of PBzMA-b-PDMAEMA copolymer, synthesised by group transfer polymerisation. Polymersomes display a diameter of 270 nm and a shell thickness of 11 nm. Assembly on planar surfaces was followed by means of the Quartz Crystal Microbalance with Dissipation (QCM-D) and Atomic Force Microscopy (AFM). Detailed information on the assembly mechanism and surface topology of the polymersome/polyelectrolyte films was thereby obtained. The assembly of polymersomes and PSS on top of silica particles of 500 nm in diameter was confirmed by ζ-potential measurements. Confocal laser scanning microscopy (CLSM), scanning electron microscopy (SEM) and transmission electron microscopy (TEM) revealed that polymersome/PSS coated silica particles increase in total diameter up to 3–5 μm. This hints toward the formation of densely packed polymersome layers. In addition, CLSM showed that polymersome/PSS films exhibit a high loading capacity that could potentially be used for encapsulation and delivery of diverse chemical species. These results provide an insight into the formation of multilayered films with compartmentalised hydrophilic/hydrophobic domains and may lead to the successful application of polymersomes in surface-engineered colloidal systems.
Fil: Coustet, Marcos Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas; Argentina
Fil: Irigoyen, Joseba. Centro de Investigación Cooperativa en Biomateriales. San Sebastián; España
Fil: Alonso Garcia, Teodoro. Centro de Investigación Cooperativa en Biomateriales. San Sebastián; España
Fil: Murray, Richard A.. Centro de Investigación Cooperativa en Biomateriales. San Sebastián; España
Fil: Romero, Gabriela. Centro de Investigación Cooperativa en Biomateriales. San Sebastián; España
Fil: Cortizo, Maria Susana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas; Argentina
Fil: Knoll, Wolfgang. Austrian Institute of Technology. Viena; Austria
Fil: Azzaroni, Omar. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas; Argentina
Fil: Moya, Sergio Eduardo. Centro de Investigación Cooperativa en Biomateriales. San Sebastián; España
description Hybrid polyelectrolyte multilayer systems were fabricated on top of planar surfaces and colloidal particles via layer by layer (LbL) assembly of polystyrene sulphonate (PSS) and polybenzyl methacrylate-block-poly(dimethylamino)ethyl methacrylate (PBzMA-b-PDMAEMA) polymersomes. Polymersomes were prepared by self assembly of PBzMA-b-PDMAEMA copolymer, synthesised by group transfer polymerisation. Polymersomes display a diameter of 270 nm and a shell thickness of 11 nm. Assembly on planar surfaces was followed by means of the Quartz Crystal Microbalance with Dissipation (QCM-D) and Atomic Force Microscopy (AFM). Detailed information on the assembly mechanism and surface topology of the polymersome/polyelectrolyte films was thereby obtained. The assembly of polymersomes and PSS on top of silica particles of 500 nm in diameter was confirmed by ζ-potential measurements. Confocal laser scanning microscopy (CLSM), scanning electron microscopy (SEM) and transmission electron microscopy (TEM) revealed that polymersome/PSS coated silica particles increase in total diameter up to 3–5 μm. This hints toward the formation of densely packed polymersome layers. In addition, CLSM showed that polymersome/PSS films exhibit a high loading capacity that could potentially be used for encapsulation and delivery of diverse chemical species. These results provide an insight into the formation of multilayered films with compartmentalised hydrophilic/hydrophobic domains and may lead to the successful application of polymersomes in surface-engineered colloidal systems.
publishDate 2014
dc.date.none.fl_str_mv 2014-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/32272
Alonso Garcia, Teodoro; Coustet, Marcos Eduardo; Azzaroni, Omar; Murray, Richard A.; Irigoyen, Joseba; Romero, Gabriela; et al.; Layer-by-layer assembly of polymersomes and polyelectrolytes on planar surfaces and microsized colloidal particles; Academic Press Inc Elsevier Science; Journal of Colloid and Interface Science; 421; 1-2014; 132-140
0021-9797
CONICET Digital
CONICET
url http://hdl.handle.net/11336/32272
identifier_str_mv Alonso Garcia, Teodoro; Coustet, Marcos Eduardo; Azzaroni, Omar; Murray, Richard A.; Irigoyen, Joseba; Romero, Gabriela; et al.; Layer-by-layer assembly of polymersomes and polyelectrolytes on planar surfaces and microsized colloidal particles; Academic Press Inc Elsevier Science; Journal of Colloid and Interface Science; 421; 1-2014; 132-140
0021-9797
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.jcis.2014.01.038
info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0021979714000617
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Academic Press Inc Elsevier Science
publisher.none.fl_str_mv Academic Press Inc Elsevier Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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