Role of ABCC2 common variants in intrahepatic cholestasis of pregnancy

Autores
Sookoian, Silvia Cristina; Castaño, Gustavo Osvaldo; Pirola, Carlos José
Año de publicación
2008
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The pathogenesis of intrahepatic cholestasis of pregnancy (ICP), a disorder that adversely affects maternal wellbeing and fetal outcome, is unclear. However, multiple factors probably interact along with a genetic predisposition. We would like to add some comments about a recently published concerning the role of ABCB11 and ABCC2 polymorphisms in both ICP and contraceptive-induced cholestasis, in particular at the light of our recently published findings about a positive association between ICP and ABCC2 common variants.
Fil: Sookoian, Silvia Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina
Fil: Castaño, Gustavo Osvaldo. Gobierno de la Ciudad de Buenos Aires. Hospital "Dr. Abel Zubizarreta"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Pirola, Carlos José. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina
Materia
Intrahepatic cholestasis of pregnancy
ABCC2
MRP2
Gene variants
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/104392
Acceder
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network_acronym_str CONICETDig
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network_name_str CONICET Digital (CONICET)
spelling Role of ABCC2 common variants in intrahepatic cholestasis of pregnancySookoian, Silvia CristinaCastaño, Gustavo OsvaldoPirola, Carlos JoséIntrahepatic cholestasis of pregnancyABCC2MRP2Gene variantshttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1https://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3The pathogenesis of intrahepatic cholestasis of pregnancy (ICP), a disorder that adversely affects maternal wellbeing and fetal outcome, is unclear. However, multiple factors probably interact along with a genetic predisposition. We would like to add some comments about a recently published concerning the role of ABCB11 and ABCC2 polymorphisms in both ICP and contraceptive-induced cholestasis, in particular at the light of our recently published findings about a positive association between ICP and ABCC2 common variants.Fil: Sookoian, Silvia Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; ArgentinaFil: Castaño, Gustavo Osvaldo. Gobierno de la Ciudad de Buenos Aires. Hospital "Dr. Abel Zubizarreta"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Pirola, Carlos José. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; ArgentinaW J G Press2008-04-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/104392Sookoian, Silvia Cristina; Castaño, Gustavo Osvaldo; Pirola, Carlos José; Role of ABCC2 common variants in intrahepatic cholestasis of pregnancy; W J G Press; World Journal of Gastroenterology; 14; 13; 7-4-2008; 2126-21271007-93272219-2840CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.wjgnet.com/1007-9327/full/v14/i13/2126.htminfo:eu-repo/semantics/altIdentifier/doi/10.3748/wjg.14.2126info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:03:08Zoai:ri.conicet.gov.ar:11336/104392instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:03:08.816CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Role of ABCC2 common variants in intrahepatic cholestasis of pregnancy
title Role of ABCC2 common variants in intrahepatic cholestasis of pregnancy
spellingShingle Role of ABCC2 common variants in intrahepatic cholestasis of pregnancy
Sookoian, Silvia Cristina
Intrahepatic cholestasis of pregnancy
ABCC2
MRP2
Gene variants
title_short Role of ABCC2 common variants in intrahepatic cholestasis of pregnancy
title_full Role of ABCC2 common variants in intrahepatic cholestasis of pregnancy
title_fullStr Role of ABCC2 common variants in intrahepatic cholestasis of pregnancy
title_full_unstemmed Role of ABCC2 common variants in intrahepatic cholestasis of pregnancy
title_sort Role of ABCC2 common variants in intrahepatic cholestasis of pregnancy
dc.creator.none.fl_str_mv Sookoian, Silvia Cristina
Castaño, Gustavo Osvaldo
Pirola, Carlos José
author Sookoian, Silvia Cristina
author_facet Sookoian, Silvia Cristina
Castaño, Gustavo Osvaldo
Pirola, Carlos José
author_role author
author2 Castaño, Gustavo Osvaldo
Pirola, Carlos José
author2_role author
author
dc.subject.none.fl_str_mv Intrahepatic cholestasis of pregnancy
ABCC2
MRP2
Gene variants
topic Intrahepatic cholestasis of pregnancy
ABCC2
MRP2
Gene variants
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv The pathogenesis of intrahepatic cholestasis of pregnancy (ICP), a disorder that adversely affects maternal wellbeing and fetal outcome, is unclear. However, multiple factors probably interact along with a genetic predisposition. We would like to add some comments about a recently published concerning the role of ABCB11 and ABCC2 polymorphisms in both ICP and contraceptive-induced cholestasis, in particular at the light of our recently published findings about a positive association between ICP and ABCC2 common variants.
Fil: Sookoian, Silvia Cristina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina
Fil: Castaño, Gustavo Osvaldo. Gobierno de la Ciudad de Buenos Aires. Hospital "Dr. Abel Zubizarreta"; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina
Fil: Pirola, Carlos José. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Médicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; Argentina
description The pathogenesis of intrahepatic cholestasis of pregnancy (ICP), a disorder that adversely affects maternal wellbeing and fetal outcome, is unclear. However, multiple factors probably interact along with a genetic predisposition. We would like to add some comments about a recently published concerning the role of ABCB11 and ABCC2 polymorphisms in both ICP and contraceptive-induced cholestasis, in particular at the light of our recently published findings about a positive association between ICP and ABCC2 common variants.
publishDate 2008
dc.date.none.fl_str_mv 2008-04-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/104392
Sookoian, Silvia Cristina; Castaño, Gustavo Osvaldo; Pirola, Carlos José; Role of ABCC2 common variants in intrahepatic cholestasis of pregnancy; W J G Press; World Journal of Gastroenterology; 14; 13; 7-4-2008; 2126-2127
1007-9327
2219-2840
CONICET Digital
CONICET
url http://hdl.handle.net/11336/104392
identifier_str_mv Sookoian, Silvia Cristina; Castaño, Gustavo Osvaldo; Pirola, Carlos José; Role of ABCC2 common variants in intrahepatic cholestasis of pregnancy; W J G Press; World Journal of Gastroenterology; 14; 13; 7-4-2008; 2126-2127
1007-9327
2219-2840
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.wjgnet.com/1007-9327/full/v14/i13/2126.htm
info:eu-repo/semantics/altIdentifier/doi/10.3748/wjg.14.2126
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv W J G Press
publisher.none.fl_str_mv W J G Press
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1842269784639537152
score 13.13397

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