Palladium-Catalyzed Direct C-H Arylation of 3-(Methylsulfinyl)thiophenes

Autores
Jiang, Hui; Bellomo Peraza, Ana Ines; Zhang, Mengnan; Carroll, Patrick J.; Manor, Brian C.; Jia, Tiezheng; Walsh, Patrick J.
Año de publicación
2018
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
A palladium-catalyzed direct arylation of (3-thiophene)S(O)Me derivatives has been developed. This protocol is effective for the selective synthesis of 2-arylated and 2,5-diarylated sulfinylthiophene derivatives with as low as 0.5 mol % catalyst loading. Various functional groups are well tolerated. A method to install two different aryl groups on 3-(methylsulfinyl)thiophenes is also introduced.
Fil: Jiang, Hui. University of Pennsylvania; Estados Unidos. Southern University Of Science And Technology; China
Fil: Bellomo Peraza, Ana Ines. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. University of Pennsylvania; Estados Unidos
Fil: Zhang, Mengnan. University of Pennsylvania; Estados Unidos
Fil: Carroll, Patrick J.. University of Pennsylvania; Estados Unidos
Fil: Manor, Brian C.. University of Pennsylvania; Estados Unidos
Fil: Jia, Tiezheng. Southern University Of Science And Technology; China
Fil: Walsh, Patrick J.. University of Pennsylvania; Estados Unidos
Materia
DIRECT ARYLATION
HIGH THROUGHPUT SCREENING
SULFINYL THIOPHENES
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/98977
Acceder
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network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Palladium-Catalyzed Direct C-H Arylation of 3-(Methylsulfinyl)thiophenesJiang, HuiBellomo Peraza, Ana InesZhang, MengnanCarroll, Patrick J.Manor, Brian C.Jia, TiezhengWalsh, Patrick J.DIRECT ARYLATIONHIGH THROUGHPUT SCREENINGSULFINYL THIOPHENEShttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1A palladium-catalyzed direct arylation of (3-thiophene)S(O)Me derivatives has been developed. This protocol is effective for the selective synthesis of 2-arylated and 2,5-diarylated sulfinylthiophene derivatives with as low as 0.5 mol % catalyst loading. Various functional groups are well tolerated. A method to install two different aryl groups on 3-(methylsulfinyl)thiophenes is also introduced.Fil: Jiang, Hui. University of Pennsylvania; Estados Unidos. Southern University Of Science And Technology; ChinaFil: Bellomo Peraza, Ana Ines. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. University of Pennsylvania; Estados UnidosFil: Zhang, Mengnan. University of Pennsylvania; Estados UnidosFil: Carroll, Patrick J.. University of Pennsylvania; Estados UnidosFil: Manor, Brian C.. University of Pennsylvania; Estados UnidosFil: Jia, Tiezheng. Southern University Of Science And Technology; ChinaFil: Walsh, Patrick J.. University of Pennsylvania; Estados UnidosAmerican Chemical Society2018-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/98977Jiang, Hui; Bellomo Peraza, Ana Ines; Zhang, Mengnan; Carroll, Patrick J.; Manor, Brian C.; et al.; Palladium-Catalyzed Direct C-H Arylation of 3-(Methylsulfinyl)thiophenes; American Chemical Society; Organic Letters; 20; 9; 5-2018; 2522-25251523-7060CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1021/acs.orglett.8b00599info:eu-repo/semantics/altIdentifier/url/https://pubs.acs.org/doi/10.1021/acs.orglett.8b00599info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:16:44Zoai:ri.conicet.gov.ar:11336/98977instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:16:44.499CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Palladium-Catalyzed Direct C-H Arylation of 3-(Methylsulfinyl)thiophenes
title Palladium-Catalyzed Direct C-H Arylation of 3-(Methylsulfinyl)thiophenes
spellingShingle Palladium-Catalyzed Direct C-H Arylation of 3-(Methylsulfinyl)thiophenes
Jiang, Hui
DIRECT ARYLATION
HIGH THROUGHPUT SCREENING
SULFINYL THIOPHENES
title_short Palladium-Catalyzed Direct C-H Arylation of 3-(Methylsulfinyl)thiophenes
title_full Palladium-Catalyzed Direct C-H Arylation of 3-(Methylsulfinyl)thiophenes
title_fullStr Palladium-Catalyzed Direct C-H Arylation of 3-(Methylsulfinyl)thiophenes
title_full_unstemmed Palladium-Catalyzed Direct C-H Arylation of 3-(Methylsulfinyl)thiophenes
title_sort Palladium-Catalyzed Direct C-H Arylation of 3-(Methylsulfinyl)thiophenes
dc.creator.none.fl_str_mv Jiang, Hui
Bellomo Peraza, Ana Ines
Zhang, Mengnan
Carroll, Patrick J.
Manor, Brian C.
Jia, Tiezheng
Walsh, Patrick J.
author Jiang, Hui
author_facet Jiang, Hui
Bellomo Peraza, Ana Ines
Zhang, Mengnan
Carroll, Patrick J.
Manor, Brian C.
Jia, Tiezheng
Walsh, Patrick J.
author_role author
author2 Bellomo Peraza, Ana Ines
Zhang, Mengnan
Carroll, Patrick J.
Manor, Brian C.
Jia, Tiezheng
Walsh, Patrick J.
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv DIRECT ARYLATION
HIGH THROUGHPUT SCREENING
SULFINYL THIOPHENES
topic DIRECT ARYLATION
HIGH THROUGHPUT SCREENING
SULFINYL THIOPHENES
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv A palladium-catalyzed direct arylation of (3-thiophene)S(O)Me derivatives has been developed. This protocol is effective for the selective synthesis of 2-arylated and 2,5-diarylated sulfinylthiophene derivatives with as low as 0.5 mol % catalyst loading. Various functional groups are well tolerated. A method to install two different aryl groups on 3-(methylsulfinyl)thiophenes is also introduced.
Fil: Jiang, Hui. University of Pennsylvania; Estados Unidos. Southern University Of Science And Technology; China
Fil: Bellomo Peraza, Ana Ines. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. University of Pennsylvania; Estados Unidos
Fil: Zhang, Mengnan. University of Pennsylvania; Estados Unidos
Fil: Carroll, Patrick J.. University of Pennsylvania; Estados Unidos
Fil: Manor, Brian C.. University of Pennsylvania; Estados Unidos
Fil: Jia, Tiezheng. Southern University Of Science And Technology; China
Fil: Walsh, Patrick J.. University of Pennsylvania; Estados Unidos
description A palladium-catalyzed direct arylation of (3-thiophene)S(O)Me derivatives has been developed. This protocol is effective for the selective synthesis of 2-arylated and 2,5-diarylated sulfinylthiophene derivatives with as low as 0.5 mol % catalyst loading. Various functional groups are well tolerated. A method to install two different aryl groups on 3-(methylsulfinyl)thiophenes is also introduced.
publishDate 2018
dc.date.none.fl_str_mv 2018-05
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/98977
Jiang, Hui; Bellomo Peraza, Ana Ines; Zhang, Mengnan; Carroll, Patrick J.; Manor, Brian C.; et al.; Palladium-Catalyzed Direct C-H Arylation of 3-(Methylsulfinyl)thiophenes; American Chemical Society; Organic Letters; 20; 9; 5-2018; 2522-2525
1523-7060
CONICET Digital
CONICET
url http://hdl.handle.net/11336/98977
identifier_str_mv Jiang, Hui; Bellomo Peraza, Ana Ines; Zhang, Mengnan; Carroll, Patrick J.; Manor, Brian C.; et al.; Palladium-Catalyzed Direct C-H Arylation of 3-(Methylsulfinyl)thiophenes; American Chemical Society; Organic Letters; 20; 9; 5-2018; 2522-2525
1523-7060
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1021/acs.orglett.8b00599
info:eu-repo/semantics/altIdentifier/url/https://pubs.acs.org/doi/10.1021/acs.orglett.8b00599
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv American Chemical Society
publisher.none.fl_str_mv American Chemical Society
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.982451

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