Hydrogen bonding interactions in fluorinated 1,2,3-triazole derivatives

Autores
Espitia Cogollo, Edeimis; Piro, Oscar Enrique; Echeverría, Gustavo Alberto; Tuttolomondo, María Eugenia; Perez, Hiram; Jios, Jorge Luis; Ulic, Sonia Elizabeth
Año de publicación
2020
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The study of the intra- and intermolecular interactions in the solid state of four related fluorine-containing 1,2,3-triazole derivatives (1: R = -H,2: R = -NO2,3: R = -CH3,4: R = -Cl) was carried out using quantum chemical calculations, vibrational (IR and Raman) and solid phase UV-vis spectroscopy, and single-crystal X-ray diffraction methods. The enol-keto/keto-enol tautomerism on theo-hydroxyacetophenone moiety was analyzed in terms of the synergy between O-H⋯O intramolecular hydrogen bond strengthening and the enhancement of π delocalization within the pseudo ring. The preference of the enol-keto form was attributed to the aromatic stabilization energy. The proton in the triazole ring was located on the intermediate nitrogen atom, with no evidence of prototropy in the studied series. Compounds1and4have similar structural motifs with N-H⋯O hydrogen bonds connecting amino and carbonyl groups of neighboring molecules in a chain along thea-axis. For2, it was found that both oxygen atoms of the nitro substituent participate as acceptors, connecting adjacent molecules by hydrogen bonds through the N-H and O-H groups. In compound3, the crystallization water molecule dominates the hydrogen bonding interactions, which associates three molecules of3, giving rise to a three-dimensional H-bonding network. These intra and intermolecular interactions, which affect the absorption band locations of the involved groups, were also detected in the vibrational spectra of the studied triazoles.
Fil: Espitia Cogollo, Edeimis. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Química Inorgánica "Dr. Pedro J. Aymonino". Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Química Inorgánica "Dr. Pedro J. Aymonino"; Argentina
Fil: Piro, Oscar Enrique. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Física; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Física La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Física La Plata; Argentina
Fil: Echeverría, Gustavo Alberto. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Física; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Física La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Física La Plata; Argentina
Fil: Tuttolomondo, María Eugenia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Química del Noroeste. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Química del Noroeste; Argentina
Fil: Perez, Hiram. Universidad de La Habana; Cuba
Fil: Jios, Jorge Luis. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Química; Argentina. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; Argentina
Fil: Ulic, Sonia Elizabeth. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Química Inorgánica "Dr. Pedro J. Aymonino". Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Química Inorgánica "Dr. Pedro J. Aymonino"; Argentina. Universidad Nacional de Luján. Departamento de Ciencias Básicas; Argentina
Materia
X-ray crystal structure
Molecular Interactions
Vibrational Spectroscopy
Pixel energies
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/143651
Acceder
id CONICETDig_f78eada14566426ec3769dd081859597
oai_identifier_str oai:ri.conicet.gov.ar:11336/143651
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Hydrogen bonding interactions in fluorinated 1,2,3-triazole derivativesEspitia Cogollo, EdeimisPiro, Oscar EnriqueEcheverría, Gustavo AlbertoTuttolomondo, María EugeniaPerez, HiramJios, Jorge LuisUlic, Sonia ElizabethX-ray crystal structureMolecular InteractionsVibrational SpectroscopyPixel energieshttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1The study of the intra- and intermolecular interactions in the solid state of four related fluorine-containing 1,2,3-triazole derivatives (1: R = -H,2: R = -NO2,3: R = -CH3,4: R = -Cl) was carried out using quantum chemical calculations, vibrational (IR and Raman) and solid phase UV-vis spectroscopy, and single-crystal X-ray diffraction methods. The enol-keto/keto-enol tautomerism on theo-hydroxyacetophenone moiety was analyzed in terms of the synergy between O-H⋯O intramolecular hydrogen bond strengthening and the enhancement of π delocalization within the pseudo ring. The preference of the enol-keto form was attributed to the aromatic stabilization energy. The proton in the triazole ring was located on the intermediate nitrogen atom, with no evidence of prototropy in the studied series. Compounds1and4have similar structural motifs with N-H⋯O hydrogen bonds connecting amino and carbonyl groups of neighboring molecules in a chain along thea-axis. For2, it was found that both oxygen atoms of the nitro substituent participate as acceptors, connecting adjacent molecules by hydrogen bonds through the N-H and O-H groups. In compound3, the crystallization water molecule dominates the hydrogen bonding interactions, which associates three molecules of3, giving rise to a three-dimensional H-bonding network. These intra and intermolecular interactions, which affect the absorption band locations of the involved groups, were also detected in the vibrational spectra of the studied triazoles.Fil: Espitia Cogollo, Edeimis. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Química Inorgánica "Dr. Pedro J. Aymonino". Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Química Inorgánica "Dr. Pedro J. Aymonino"; ArgentinaFil: Piro, Oscar Enrique. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Física; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Física La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Física La Plata; ArgentinaFil: Echeverría, Gustavo Alberto. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Física; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Física La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Física La Plata; ArgentinaFil: Tuttolomondo, María Eugenia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Química del Noroeste. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Química del Noroeste; ArgentinaFil: Perez, Hiram. Universidad de La Habana; CubaFil: Jios, Jorge Luis. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Química; Argentina. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; ArgentinaFil: Ulic, Sonia Elizabeth. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Química Inorgánica "Dr. Pedro J. Aymonino". Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Química Inorgánica "Dr. Pedro J. Aymonino"; Argentina. Universidad Nacional de Luján. Departamento de Ciencias Básicas; ArgentinaRoyal Society of Chemistry2020-08-24info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/143651Espitia Cogollo, Edeimis; Piro, Oscar Enrique; Echeverría, Gustavo Alberto; Tuttolomondo, María Eugenia; Perez, Hiram; et al.; Hydrogen bonding interactions in fluorinated 1,2,3-triazole derivatives; Royal Society of Chemistry; New Journal of Chemistry; 44; 37; 24-8-2020; 16006-160191144-05461369-9261CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://pubs.rsc.org/en/Content/ArticleLanding/2020/NJ/D0NJ02914Ainfo:eu-repo/semantics/altIdentifier/doi/10.1039/D0NJ02914Ainfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-22T11:12:10Zoai:ri.conicet.gov.ar:11336/143651instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-22 11:12:10.514CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Hydrogen bonding interactions in fluorinated 1,2,3-triazole derivatives
title Hydrogen bonding interactions in fluorinated 1,2,3-triazole derivatives
spellingShingle Hydrogen bonding interactions in fluorinated 1,2,3-triazole derivatives
Espitia Cogollo, Edeimis
X-ray crystal structure
Molecular Interactions
Vibrational Spectroscopy
Pixel energies
title_short Hydrogen bonding interactions in fluorinated 1,2,3-triazole derivatives
title_full Hydrogen bonding interactions in fluorinated 1,2,3-triazole derivatives
title_fullStr Hydrogen bonding interactions in fluorinated 1,2,3-triazole derivatives
title_full_unstemmed Hydrogen bonding interactions in fluorinated 1,2,3-triazole derivatives
title_sort Hydrogen bonding interactions in fluorinated 1,2,3-triazole derivatives
dc.creator.none.fl_str_mv Espitia Cogollo, Edeimis
Piro, Oscar Enrique
Echeverría, Gustavo Alberto
Tuttolomondo, María Eugenia
Perez, Hiram
Jios, Jorge Luis
Ulic, Sonia Elizabeth
author Espitia Cogollo, Edeimis
author_facet Espitia Cogollo, Edeimis
Piro, Oscar Enrique
Echeverría, Gustavo Alberto
Tuttolomondo, María Eugenia
Perez, Hiram
Jios, Jorge Luis
Ulic, Sonia Elizabeth
author_role author
author2 Piro, Oscar Enrique
Echeverría, Gustavo Alberto
Tuttolomondo, María Eugenia
Perez, Hiram
Jios, Jorge Luis
Ulic, Sonia Elizabeth
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv X-ray crystal structure
Molecular Interactions
Vibrational Spectroscopy
Pixel energies
topic X-ray crystal structure
Molecular Interactions
Vibrational Spectroscopy
Pixel energies
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv The study of the intra- and intermolecular interactions in the solid state of four related fluorine-containing 1,2,3-triazole derivatives (1: R = -H,2: R = -NO2,3: R = -CH3,4: R = -Cl) was carried out using quantum chemical calculations, vibrational (IR and Raman) and solid phase UV-vis spectroscopy, and single-crystal X-ray diffraction methods. The enol-keto/keto-enol tautomerism on theo-hydroxyacetophenone moiety was analyzed in terms of the synergy between O-H⋯O intramolecular hydrogen bond strengthening and the enhancement of π delocalization within the pseudo ring. The preference of the enol-keto form was attributed to the aromatic stabilization energy. The proton in the triazole ring was located on the intermediate nitrogen atom, with no evidence of prototropy in the studied series. Compounds1and4have similar structural motifs with N-H⋯O hydrogen bonds connecting amino and carbonyl groups of neighboring molecules in a chain along thea-axis. For2, it was found that both oxygen atoms of the nitro substituent participate as acceptors, connecting adjacent molecules by hydrogen bonds through the N-H and O-H groups. In compound3, the crystallization water molecule dominates the hydrogen bonding interactions, which associates three molecules of3, giving rise to a three-dimensional H-bonding network. These intra and intermolecular interactions, which affect the absorption band locations of the involved groups, were also detected in the vibrational spectra of the studied triazoles.
Fil: Espitia Cogollo, Edeimis. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Química Inorgánica "Dr. Pedro J. Aymonino". Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Química Inorgánica "Dr. Pedro J. Aymonino"; Argentina
Fil: Piro, Oscar Enrique. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Física; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Física La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Física La Plata; Argentina
Fil: Echeverría, Gustavo Alberto. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Física; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Física La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Física La Plata; Argentina
Fil: Tuttolomondo, María Eugenia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto de Química del Noroeste. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia. Instituto de Química del Noroeste; Argentina
Fil: Perez, Hiram. Universidad de La Habana; Cuba
Fil: Jios, Jorge Luis. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Departamento de Química; Argentina. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; Argentina
Fil: Ulic, Sonia Elizabeth. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Química Inorgánica "Dr. Pedro J. Aymonino". Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Química Inorgánica "Dr. Pedro J. Aymonino"; Argentina. Universidad Nacional de Luján. Departamento de Ciencias Básicas; Argentina
description The study of the intra- and intermolecular interactions in the solid state of four related fluorine-containing 1,2,3-triazole derivatives (1: R = -H,2: R = -NO2,3: R = -CH3,4: R = -Cl) was carried out using quantum chemical calculations, vibrational (IR and Raman) and solid phase UV-vis spectroscopy, and single-crystal X-ray diffraction methods. The enol-keto/keto-enol tautomerism on theo-hydroxyacetophenone moiety was analyzed in terms of the synergy between O-H⋯O intramolecular hydrogen bond strengthening and the enhancement of π delocalization within the pseudo ring. The preference of the enol-keto form was attributed to the aromatic stabilization energy. The proton in the triazole ring was located on the intermediate nitrogen atom, with no evidence of prototropy in the studied series. Compounds1and4have similar structural motifs with N-H⋯O hydrogen bonds connecting amino and carbonyl groups of neighboring molecules in a chain along thea-axis. For2, it was found that both oxygen atoms of the nitro substituent participate as acceptors, connecting adjacent molecules by hydrogen bonds through the N-H and O-H groups. In compound3, the crystallization water molecule dominates the hydrogen bonding interactions, which associates three molecules of3, giving rise to a three-dimensional H-bonding network. These intra and intermolecular interactions, which affect the absorption band locations of the involved groups, were also detected in the vibrational spectra of the studied triazoles.
publishDate 2020
dc.date.none.fl_str_mv 2020-08-24
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/143651
Espitia Cogollo, Edeimis; Piro, Oscar Enrique; Echeverría, Gustavo Alberto; Tuttolomondo, María Eugenia; Perez, Hiram; et al.; Hydrogen bonding interactions in fluorinated 1,2,3-triazole derivatives; Royal Society of Chemistry; New Journal of Chemistry; 44; 37; 24-8-2020; 16006-16019
1144-0546
1369-9261
CONICET Digital
CONICET
url http://hdl.handle.net/11336/143651
identifier_str_mv Espitia Cogollo, Edeimis; Piro, Oscar Enrique; Echeverría, Gustavo Alberto; Tuttolomondo, María Eugenia; Perez, Hiram; et al.; Hydrogen bonding interactions in fluorinated 1,2,3-triazole derivatives; Royal Society of Chemistry; New Journal of Chemistry; 44; 37; 24-8-2020; 16006-16019
1144-0546
1369-9261
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://pubs.rsc.org/en/Content/ArticleLanding/2020/NJ/D0NJ02914A
info:eu-repo/semantics/altIdentifier/doi/10.1039/D0NJ02914A
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Royal Society of Chemistry
publisher.none.fl_str_mv Royal Society of Chemistry
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 12.982451

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