Contrasting Patterns of Nuclear and mtDNA Diversity in Native American Populations
- Autores
- Yang, Ning Ning; Mazières, Stephane; Bravi, Claudio Marcelo; Ray, Nicolas; Wang, Sijia; Burley, Mari-Wyn; Bedoya Berrío, Gabriel; Rojas, Winston; Parra, María Verónica; Molina, Julio A.; Gallo, Carla; Poletti, Giovanni; Hill, Kim; Hurtado, Ana M.; Petzl Erler, Maria L.; Tsuneto, Luiza T.; Klitz, William; Barrantes, Ramiro; Llop, Elena; Rothhammer, Francisco; Labuda, Damian; Salzano, Francisco M.; Bortolini, María Cátira; Excoffier, Laurent; Dugoujon, Jean Michel; Ruiz-Linares, Andres
- Año de publicación
- 2010
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- We report an integrated analysis of nuclear (autosomal, X- and Y-chromosome) short tandem repeat (STR) data and mtDNA D-loop sequences obtained in the same set of 22 Native populations from across the Americas. A north to south gradient of decreasing population diversity was observed, in agreement with a settlement of the Americas from the extreme northwest of the continent. This correlation is stronger with "least cost distances," which consider the coasts as facilitators of migration. Continent-wide estimates of population structure are highest for the Y-chromosome and lowest for the autosomes, consistent with the effective size of the different marker systems examined. Population differentiation is highest in East South America and lowest in Meso America and the Andean region. Regional analyses suggest a deviation from mutation-drift equilibrium consistent with population expansion in Meso America and the Andes and population contraction in Northwest and East South America. These data hint at an early divergence of Andean and non-Andean South Americans and at a contrasting demographic history for populations from these regions.
Fil: Yang, Ning Ning. Colegio Universitario de Londres; Reino Unido
Fil: Mazières, Stephane. Centre National de la Recherche Scientifique; Francia. Université Paul Sabatier; Francia
Fil: Bravi, Claudio Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; Argentina
Fil: Ray, Nicolas. Universidad de Ginebra; Suiza
Fil: Wang, Sijia. Harvard University; Estados Unidos
Fil: Burley, Mari-Wyn. Colegio Universitario de Londres; Reino Unido
Fil: Bedoya Berrío, Gabriel. Universidad de Antioquia; Colombia
Fil: Rojas, Winston. Universidad de Antioquia; Colombia
Fil: Parra, María Verónica. Universidad de Antioquia; Colombia
Fil: Molina, Julio A.. Centro de Investigaciones Biomédicas de Guatemala; Guatemala
Fil: Gallo, Carla. Universidad Peruana Cayetano Heredia; Perú
Fil: Poletti, Giovanni. Universidad Peruana Cayetano Heredia; Perú
Fil: Hill, Kim. Arizona State University; Estados Unidos
Fil: Hurtado, Ana M.. Arizona State University; Estados Unidos
Fil: Petzl Erler, Maria L.. Universidade Federal do Paraná; Brasil
Fil: Tsuneto, Luiza T.. Universidade Federal do Paraná; Brasil
Fil: Klitz, William. University of California at Berkeley; Estados Unidos. Public Health Institute; Estados Unidos
Fil: Barrantes, Ramiro. Universidad de Costa Rica; Costa Rica
Fil: Llop, Elena. Universidad de Tarapacá; Chile. Universidad de Chile; Chile
Fil: Rothhammer, Francisco. Universidad de Chile; Chile. Universidad de Tarapacá; Chile
Fil: Labuda, Damian. University of Montreal; Canadá
Fil: Salzano, Francisco M.. Universidade Federal do Rio Grande do Sul; Brasil
Fil: Bortolini, María Cátira. Universidade Federal do Rio Grande do Sul; Brasil
Fil: Excoffier, Laurent. Swiss Institute of Bioinformatics; Suiza. University of Bern; Suiza
Fil: Dugoujon, Jean Michel. Université Paul Sabatier; Francia. Centre National de la Recherche Scientifique; Francia
Fil: Ruiz-Linares, Andres. Colegio Universitario de Londres; Reino Unido - Materia
-
AMERIINDIANS
MTDNA
STRS
X-CHROMOSOME
Y-CHROMOSOME - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
.jpg)
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/95481
Ver los metadatos del registro completo
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Contrasting Patterns of Nuclear and mtDNA Diversity in Native American PopulationsYang, Ning NingMazières, StephaneBravi, Claudio MarceloRay, NicolasWang, SijiaBurley, Mari-WynBedoya Berrío, GabrielRojas, WinstonParra, María VerónicaMolina, Julio A.Gallo, CarlaPoletti, GiovanniHill, KimHurtado, Ana M.Petzl Erler, Maria L.Tsuneto, Luiza T.Klitz, WilliamBarrantes, RamiroLlop, ElenaRothhammer, FranciscoLabuda, DamianSalzano, Francisco M.Bortolini, María CátiraExcoffier, LaurentDugoujon, Jean MichelRuiz-Linares, AndresAMERIINDIANSMTDNASTRSX-CHROMOSOMEY-CHROMOSOMEhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1We report an integrated analysis of nuclear (autosomal, X- and Y-chromosome) short tandem repeat (STR) data and mtDNA D-loop sequences obtained in the same set of 22 Native populations from across the Americas. A north to south gradient of decreasing population diversity was observed, in agreement with a settlement of the Americas from the extreme northwest of the continent. This correlation is stronger with "least cost distances," which consider the coasts as facilitators of migration. Continent-wide estimates of population structure are highest for the Y-chromosome and lowest for the autosomes, consistent with the effective size of the different marker systems examined. Population differentiation is highest in East South America and lowest in Meso America and the Andean region. Regional analyses suggest a deviation from mutation-drift equilibrium consistent with population expansion in Meso America and the Andes and population contraction in Northwest and East South America. These data hint at an early divergence of Andean and non-Andean South Americans and at a contrasting demographic history for populations from these regions.Fil: Yang, Ning Ning. Colegio Universitario de Londres; Reino UnidoFil: Mazières, Stephane. Centre National de la Recherche Scientifique; Francia. Université Paul Sabatier; FranciaFil: Bravi, Claudio Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; ArgentinaFil: Ray, Nicolas. Universidad de Ginebra; SuizaFil: Wang, Sijia. Harvard University; Estados UnidosFil: Burley, Mari-Wyn. Colegio Universitario de Londres; Reino UnidoFil: Bedoya Berrío, Gabriel. Universidad de Antioquia; ColombiaFil: Rojas, Winston. Universidad de Antioquia; ColombiaFil: Parra, María Verónica. Universidad de Antioquia; ColombiaFil: Molina, Julio A.. Centro de Investigaciones Biomédicas de Guatemala; GuatemalaFil: Gallo, Carla. Universidad Peruana Cayetano Heredia; PerúFil: Poletti, Giovanni. Universidad Peruana Cayetano Heredia; PerúFil: Hill, Kim. Arizona State University; Estados UnidosFil: Hurtado, Ana M.. Arizona State University; Estados UnidosFil: Petzl Erler, Maria L.. Universidade Federal do Paraná; BrasilFil: Tsuneto, Luiza T.. Universidade Federal do Paraná; BrasilFil: Klitz, William. University of California at Berkeley; Estados Unidos. Public Health Institute; Estados UnidosFil: Barrantes, Ramiro. Universidad de Costa Rica; Costa RicaFil: Llop, Elena. Universidad de Tarapacá; Chile. Universidad de Chile; ChileFil: Rothhammer, Francisco. Universidad de Chile; Chile. Universidad de Tarapacá; ChileFil: Labuda, Damian. University of Montreal; CanadáFil: Salzano, Francisco M.. Universidade Federal do Rio Grande do Sul; BrasilFil: Bortolini, María Cátira. Universidade Federal do Rio Grande do Sul; BrasilFil: Excoffier, Laurent. Swiss Institute of Bioinformatics; Suiza. University of Bern; SuizaFil: Dugoujon, Jean Michel. Université Paul Sabatier; Francia. Centre National de la Recherche Scientifique; FranciaFil: Ruiz-Linares, Andres. Colegio Universitario de Londres; Reino UnidoWiley Blackwell Publishing, Inc2010-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/95481Yang, Ning Ning; Mazières, Stephane; Bravi, Claudio Marcelo; Ray, Nicolas; Wang, Sijia; et al.; Contrasting Patterns of Nuclear and mtDNA Diversity in Native American Populations; Wiley Blackwell Publishing, Inc; Annals Of Human Genetics; 74; 6; 11-2010; 525-5380003-4800CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1469-1809.2010.00608.xinfo:eu-repo/semantics/altIdentifier/doi/10.1111/j.1469-1809.2010.00608.xinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-10-15T15:27:05Zoai:ri.conicet.gov.ar:11336/95481instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-10-15 15:27:05.498CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
| dc.title.none.fl_str_mv |
Contrasting Patterns of Nuclear and mtDNA Diversity in Native American Populations |
| title |
Contrasting Patterns of Nuclear and mtDNA Diversity in Native American Populations |
| spellingShingle |
Contrasting Patterns of Nuclear and mtDNA Diversity in Native American Populations Yang, Ning Ning AMERIINDIANS MTDNA STRS X-CHROMOSOME Y-CHROMOSOME |
| title_short |
Contrasting Patterns of Nuclear and mtDNA Diversity in Native American Populations |
| title_full |
Contrasting Patterns of Nuclear and mtDNA Diversity in Native American Populations |
| title_fullStr |
Contrasting Patterns of Nuclear and mtDNA Diversity in Native American Populations |
| title_full_unstemmed |
Contrasting Patterns of Nuclear and mtDNA Diversity in Native American Populations |
| title_sort |
Contrasting Patterns of Nuclear and mtDNA Diversity in Native American Populations |
| dc.creator.none.fl_str_mv |
Yang, Ning Ning Mazières, Stephane Bravi, Claudio Marcelo Ray, Nicolas Wang, Sijia Burley, Mari-Wyn Bedoya Berrío, Gabriel Rojas, Winston Parra, María Verónica Molina, Julio A. Gallo, Carla Poletti, Giovanni Hill, Kim Hurtado, Ana M. Petzl Erler, Maria L. Tsuneto, Luiza T. Klitz, William Barrantes, Ramiro Llop, Elena Rothhammer, Francisco Labuda, Damian Salzano, Francisco M. Bortolini, María Cátira Excoffier, Laurent Dugoujon, Jean Michel Ruiz-Linares, Andres |
| author |
Yang, Ning Ning |
| author_facet |
Yang, Ning Ning Mazières, Stephane Bravi, Claudio Marcelo Ray, Nicolas Wang, Sijia Burley, Mari-Wyn Bedoya Berrío, Gabriel Rojas, Winston Parra, María Verónica Molina, Julio A. Gallo, Carla Poletti, Giovanni Hill, Kim Hurtado, Ana M. Petzl Erler, Maria L. Tsuneto, Luiza T. Klitz, William Barrantes, Ramiro Llop, Elena Rothhammer, Francisco Labuda, Damian Salzano, Francisco M. Bortolini, María Cátira Excoffier, Laurent Dugoujon, Jean Michel Ruiz-Linares, Andres |
| author_role |
author |
| author2 |
Mazières, Stephane Bravi, Claudio Marcelo Ray, Nicolas Wang, Sijia Burley, Mari-Wyn Bedoya Berrío, Gabriel Rojas, Winston Parra, María Verónica Molina, Julio A. Gallo, Carla Poletti, Giovanni Hill, Kim Hurtado, Ana M. Petzl Erler, Maria L. Tsuneto, Luiza T. Klitz, William Barrantes, Ramiro Llop, Elena Rothhammer, Francisco Labuda, Damian Salzano, Francisco M. Bortolini, María Cátira Excoffier, Laurent Dugoujon, Jean Michel Ruiz-Linares, Andres |
| author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author |
| dc.subject.none.fl_str_mv |
AMERIINDIANS MTDNA STRS X-CHROMOSOME Y-CHROMOSOME |
| topic |
AMERIINDIANS MTDNA STRS X-CHROMOSOME Y-CHROMOSOME |
| purl_subject.fl_str_mv |
https://purl.org/becyt/ford/1.6 https://purl.org/becyt/ford/1 |
| dc.description.none.fl_txt_mv |
We report an integrated analysis of nuclear (autosomal, X- and Y-chromosome) short tandem repeat (STR) data and mtDNA D-loop sequences obtained in the same set of 22 Native populations from across the Americas. A north to south gradient of decreasing population diversity was observed, in agreement with a settlement of the Americas from the extreme northwest of the continent. This correlation is stronger with "least cost distances," which consider the coasts as facilitators of migration. Continent-wide estimates of population structure are highest for the Y-chromosome and lowest for the autosomes, consistent with the effective size of the different marker systems examined. Population differentiation is highest in East South America and lowest in Meso America and the Andean region. Regional analyses suggest a deviation from mutation-drift equilibrium consistent with population expansion in Meso America and the Andes and population contraction in Northwest and East South America. These data hint at an early divergence of Andean and non-Andean South Americans and at a contrasting demographic history for populations from these regions. Fil: Yang, Ning Ning. Colegio Universitario de Londres; Reino Unido Fil: Mazières, Stephane. Centre National de la Recherche Scientifique; Francia. Université Paul Sabatier; Francia Fil: Bravi, Claudio Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto Multidisciplinario de Biología Celular. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Instituto Multidisciplinario de Biología Celular. Universidad Nacional de La Plata. Instituto Multidisciplinario de Biología Celular; Argentina Fil: Ray, Nicolas. Universidad de Ginebra; Suiza Fil: Wang, Sijia. Harvard University; Estados Unidos Fil: Burley, Mari-Wyn. Colegio Universitario de Londres; Reino Unido Fil: Bedoya Berrío, Gabriel. Universidad de Antioquia; Colombia Fil: Rojas, Winston. Universidad de Antioquia; Colombia Fil: Parra, María Verónica. Universidad de Antioquia; Colombia Fil: Molina, Julio A.. Centro de Investigaciones Biomédicas de Guatemala; Guatemala Fil: Gallo, Carla. Universidad Peruana Cayetano Heredia; Perú Fil: Poletti, Giovanni. Universidad Peruana Cayetano Heredia; Perú Fil: Hill, Kim. Arizona State University; Estados Unidos Fil: Hurtado, Ana M.. Arizona State University; Estados Unidos Fil: Petzl Erler, Maria L.. Universidade Federal do Paraná; Brasil Fil: Tsuneto, Luiza T.. Universidade Federal do Paraná; Brasil Fil: Klitz, William. University of California at Berkeley; Estados Unidos. Public Health Institute; Estados Unidos Fil: Barrantes, Ramiro. Universidad de Costa Rica; Costa Rica Fil: Llop, Elena. Universidad de Tarapacá; Chile. Universidad de Chile; Chile Fil: Rothhammer, Francisco. Universidad de Chile; Chile. Universidad de Tarapacá; Chile Fil: Labuda, Damian. University of Montreal; Canadá Fil: Salzano, Francisco M.. Universidade Federal do Rio Grande do Sul; Brasil Fil: Bortolini, María Cátira. Universidade Federal do Rio Grande do Sul; Brasil Fil: Excoffier, Laurent. Swiss Institute of Bioinformatics; Suiza. University of Bern; Suiza Fil: Dugoujon, Jean Michel. Université Paul Sabatier; Francia. Centre National de la Recherche Scientifique; Francia Fil: Ruiz-Linares, Andres. Colegio Universitario de Londres; Reino Unido |
| description |
We report an integrated analysis of nuclear (autosomal, X- and Y-chromosome) short tandem repeat (STR) data and mtDNA D-loop sequences obtained in the same set of 22 Native populations from across the Americas. A north to south gradient of decreasing population diversity was observed, in agreement with a settlement of the Americas from the extreme northwest of the continent. This correlation is stronger with "least cost distances," which consider the coasts as facilitators of migration. Continent-wide estimates of population structure are highest for the Y-chromosome and lowest for the autosomes, consistent with the effective size of the different marker systems examined. Population differentiation is highest in East South America and lowest in Meso America and the Andean region. Regional analyses suggest a deviation from mutation-drift equilibrium consistent with population expansion in Meso America and the Andes and population contraction in Northwest and East South America. These data hint at an early divergence of Andean and non-Andean South Americans and at a contrasting demographic history for populations from these regions. |
| publishDate |
2010 |
| dc.date.none.fl_str_mv |
2010-11 |
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info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
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article |
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publishedVersion |
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http://hdl.handle.net/11336/95481 Yang, Ning Ning; Mazières, Stephane; Bravi, Claudio Marcelo; Ray, Nicolas; Wang, Sijia; et al.; Contrasting Patterns of Nuclear and mtDNA Diversity in Native American Populations; Wiley Blackwell Publishing, Inc; Annals Of Human Genetics; 74; 6; 11-2010; 525-538 0003-4800 CONICET Digital CONICET |
| url |
http://hdl.handle.net/11336/95481 |
| identifier_str_mv |
Yang, Ning Ning; Mazières, Stephane; Bravi, Claudio Marcelo; Ray, Nicolas; Wang, Sijia; et al.; Contrasting Patterns of Nuclear and mtDNA Diversity in Native American Populations; Wiley Blackwell Publishing, Inc; Annals Of Human Genetics; 74; 6; 11-2010; 525-538 0003-4800 CONICET Digital CONICET |
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eng |
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eng |
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Wiley Blackwell Publishing, Inc |
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Wiley Blackwell Publishing, Inc |
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