Use of neutron scattering techniques for Antifreeze Protein mechanistic studies

Autores
Howard, Eduardo Ignacio; Blakeley, Matthew P.; Salvay, Andrés Gerardo; Podjarny, Alberto Daniel
Año de publicación
2014
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Antifreeze proteins (AFP) have evolved in organisms living in sub-zero temperatures to avoid freezing of internal fl uids. They bind to ice nuclei lowering the freezing point and inhibiting recrystallization [1]. Even though this protein has been thoroughly studied, including several structures determined by X-ray crystallography, the exact mechanism of binding of ice to the largely hydrophobic Ice Binding Surface (IBS), (i.e. the region of the protein involved in the ice recognition) has remained unclear. In particular, the study of the hydration layers around the protein using X-ray crystallography did not provide a model of the IBS-ice interface.
Fil: Howard, Eduardo Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Física de Líquidos y Sistemas Biológicos. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Física de Líquidos y Sistemas Biológicos; Argentina
Fil: Blakeley, Matthew P.. Institut Laue Langevin; Francia
Fil: Salvay, Andrés Gerardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Física de Líquidos y Sistemas Biológicos. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Física de Líquidos y Sistemas Biológicos; Argentina. Universidad Nacional de Quilmes; Argentina
Fil: Podjarny, Alberto Daniel. Centre National de la Recherche Scientifique; Francia
Materia
X-Ray + Neutron Crystallographic
Small Angle Neutron Scattering
Type-Iii Afp
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/33886
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Use of neutron scattering techniques for Antifreeze Protein mechanistic studiesHoward, Eduardo IgnacioBlakeley, Matthew P.Salvay, Andrés GerardoPodjarny, Alberto DanielX-Ray + Neutron CrystallographicSmall Angle Neutron ScatteringType-Iii Afphttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Antifreeze proteins (AFP) have evolved in organisms living in sub-zero temperatures to avoid freezing of internal fl uids. They bind to ice nuclei lowering the freezing point and inhibiting recrystallization [1]. Even though this protein has been thoroughly studied, including several structures determined by X-ray crystallography, the exact mechanism of binding of ice to the largely hydrophobic Ice Binding Surface (IBS), (i.e. the region of the protein involved in the ice recognition) has remained unclear. In particular, the study of the hydration layers around the protein using X-ray crystallography did not provide a model of the IBS-ice interface.Fil: Howard, Eduardo Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Física de Líquidos y Sistemas Biológicos. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Física de Líquidos y Sistemas Biológicos; ArgentinaFil: Blakeley, Matthew P.. Institut Laue Langevin; FranciaFil: Salvay, Andrés Gerardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Física de Líquidos y Sistemas Biológicos. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Física de Líquidos y Sistemas Biológicos; Argentina. Universidad Nacional de Quilmes; ArgentinaFil: Podjarny, Alberto Daniel. Centre National de la Recherche Scientifique; FranciaTaylor & Francis2014-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/33886Howard, Eduardo Ignacio; Blakeley, Matthew P.; Salvay, Andrés Gerardo; Podjarny, Alberto Daniel; Use of neutron scattering techniques for Antifreeze Protein mechanistic studies; Taylor & Francis; Neutron News; 25; 4; 10-2014; 24-271044-8632CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1080/10448632.2014.955421info:eu-repo/semantics/altIdentifier/url/http://www.tandfonline.com/doi/abs/10.1080/10448632.2014.955421info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T10:08:58Zoai:ri.conicet.gov.ar:11336/33886instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 10:08:59.082CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Use of neutron scattering techniques for Antifreeze Protein mechanistic studies
title Use of neutron scattering techniques for Antifreeze Protein mechanistic studies
spellingShingle Use of neutron scattering techniques for Antifreeze Protein mechanistic studies
Howard, Eduardo Ignacio
X-Ray + Neutron Crystallographic
Small Angle Neutron Scattering
Type-Iii Afp
title_short Use of neutron scattering techniques for Antifreeze Protein mechanistic studies
title_full Use of neutron scattering techniques for Antifreeze Protein mechanistic studies
title_fullStr Use of neutron scattering techniques for Antifreeze Protein mechanistic studies
title_full_unstemmed Use of neutron scattering techniques for Antifreeze Protein mechanistic studies
title_sort Use of neutron scattering techniques for Antifreeze Protein mechanistic studies
dc.creator.none.fl_str_mv Howard, Eduardo Ignacio
Blakeley, Matthew P.
Salvay, Andrés Gerardo
Podjarny, Alberto Daniel
author Howard, Eduardo Ignacio
author_facet Howard, Eduardo Ignacio
Blakeley, Matthew P.
Salvay, Andrés Gerardo
Podjarny, Alberto Daniel
author_role author
author2 Blakeley, Matthew P.
Salvay, Andrés Gerardo
Podjarny, Alberto Daniel
author2_role author
author
author
dc.subject.none.fl_str_mv X-Ray + Neutron Crystallographic
Small Angle Neutron Scattering
Type-Iii Afp
topic X-Ray + Neutron Crystallographic
Small Angle Neutron Scattering
Type-Iii Afp
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Antifreeze proteins (AFP) have evolved in organisms living in sub-zero temperatures to avoid freezing of internal fl uids. They bind to ice nuclei lowering the freezing point and inhibiting recrystallization [1]. Even though this protein has been thoroughly studied, including several structures determined by X-ray crystallography, the exact mechanism of binding of ice to the largely hydrophobic Ice Binding Surface (IBS), (i.e. the region of the protein involved in the ice recognition) has remained unclear. In particular, the study of the hydration layers around the protein using X-ray crystallography did not provide a model of the IBS-ice interface.
Fil: Howard, Eduardo Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Física de Líquidos y Sistemas Biológicos. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Física de Líquidos y Sistemas Biológicos; Argentina
Fil: Blakeley, Matthew P.. Institut Laue Langevin; Francia
Fil: Salvay, Andrés Gerardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Física de Líquidos y Sistemas Biológicos. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Física de Líquidos y Sistemas Biológicos; Argentina. Universidad Nacional de Quilmes; Argentina
Fil: Podjarny, Alberto Daniel. Centre National de la Recherche Scientifique; Francia
description Antifreeze proteins (AFP) have evolved in organisms living in sub-zero temperatures to avoid freezing of internal fl uids. They bind to ice nuclei lowering the freezing point and inhibiting recrystallization [1]. Even though this protein has been thoroughly studied, including several structures determined by X-ray crystallography, the exact mechanism of binding of ice to the largely hydrophobic Ice Binding Surface (IBS), (i.e. the region of the protein involved in the ice recognition) has remained unclear. In particular, the study of the hydration layers around the protein using X-ray crystallography did not provide a model of the IBS-ice interface.
publishDate 2014
dc.date.none.fl_str_mv 2014-10
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/33886
Howard, Eduardo Ignacio; Blakeley, Matthew P.; Salvay, Andrés Gerardo; Podjarny, Alberto Daniel; Use of neutron scattering techniques for Antifreeze Protein mechanistic studies; Taylor & Francis; Neutron News; 25; 4; 10-2014; 24-27
1044-8632
CONICET Digital
CONICET
url http://hdl.handle.net/11336/33886
identifier_str_mv Howard, Eduardo Ignacio; Blakeley, Matthew P.; Salvay, Andrés Gerardo; Podjarny, Alberto Daniel; Use of neutron scattering techniques for Antifreeze Protein mechanistic studies; Taylor & Francis; Neutron News; 25; 4; 10-2014; 24-27
1044-8632
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1080/10448632.2014.955421
info:eu-repo/semantics/altIdentifier/url/http://www.tandfonline.com/doi/abs/10.1080/10448632.2014.955421
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Taylor & Francis
publisher.none.fl_str_mv Taylor & Francis
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.13397

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