Emergence of Pseudomonas aeruginosa strains producing metallo-β-lactamases of the IMP-15 and VIM-2 types in Mexico
- Autores
- Quinones Falconi, F.; Galicia Velasco, M.; Marchiaro, P.; Mussi, María Alejandra; Ballerini, V.; Vila, Alejandro Jose; Viale, Alejandro Miguel; Bermejo Morales, K.; Limansky, Adriana Sara
- Año de publicación
- 2010
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Eighty-six carbapenem non-susceptible Pseudomonas aeruginosa isolates collected in the National Institute of Respiratory Diseases of Mexico City were screened for the presence of metallo-beta-lactamase (MBL) activity using both E-test strips and a microbiological assay with EDTA-imipenem. Genomic comparisons and sequence analyses conducted with these isolates revealed the presence of bla(VIM-2) in two clonally related isolates, and bla(IMP-15) in a clonally unrelated isolate. Both genes were found to be carried by class 1 integrons, and bla(IMP-15) was additionally present on a broad host-range plasmid. This is the first report of co-existing P. aeruginosa strains producing different MBLs in a Mexican hospital, highlighting the necessity of appropriate surveillance to prevent dissemination of carbapenem resistance.
Fil: Quinones Falconi, F.. Instituto Nacional de Enfermedades Respiratorias; México
Fil: Galicia Velasco, M.. Instituto Nacional de Enfermedades Respiratorias; México
Fil: Marchiaro, P.. No especifíca;
Fil: Mussi, María Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Centro de Estudios Fotosintéticos y Bioquímicos. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Centro de Estudios Fotosintéticos y Bioquímicos; Argentina
Fil: Ballerini, V.. Hospital Intendente Carrasco; Argentina
Fil: Vila, Alejandro Jose. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Biología Molecular y Celular de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario; Argentina
Fil: Viale, Alejandro Miguel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Biología Molecular y Celular de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario; Argentina
Fil: Bermejo Morales, K.. Instituto Nacional de Enfermedades Respiratorias; México
Fil: Limansky, Adriana Sara. No especifíca; - Materia
-
Metalo-B-lactamasas
IMP-15
VIM-2 - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
.jpg)
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/278097
Ver los metadatos del registro completo
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Emergence of Pseudomonas aeruginosa strains producing metallo-β-lactamases of the IMP-15 and VIM-2 types in MexicoQuinones Falconi, F.Galicia Velasco, M.Marchiaro, P.Mussi, María AlejandraBallerini, V.Vila, Alejandro JoseViale, Alejandro MiguelBermejo Morales, K.Limansky, Adriana SaraMetalo-B-lactamasasIMP-15VIM-2https://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Eighty-six carbapenem non-susceptible Pseudomonas aeruginosa isolates collected in the National Institute of Respiratory Diseases of Mexico City were screened for the presence of metallo-beta-lactamase (MBL) activity using both E-test strips and a microbiological assay with EDTA-imipenem. Genomic comparisons and sequence analyses conducted with these isolates revealed the presence of bla(VIM-2) in two clonally related isolates, and bla(IMP-15) in a clonally unrelated isolate. Both genes were found to be carried by class 1 integrons, and bla(IMP-15) was additionally present on a broad host-range plasmid. This is the first report of co-existing P. aeruginosa strains producing different MBLs in a Mexican hospital, highlighting the necessity of appropriate surveillance to prevent dissemination of carbapenem resistance.Fil: Quinones Falconi, F.. Instituto Nacional de Enfermedades Respiratorias; MéxicoFil: Galicia Velasco, M.. Instituto Nacional de Enfermedades Respiratorias; MéxicoFil: Marchiaro, P.. No especifíca;Fil: Mussi, María Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Centro de Estudios Fotosintéticos y Bioquímicos. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Centro de Estudios Fotosintéticos y Bioquímicos; ArgentinaFil: Ballerini, V.. Hospital Intendente Carrasco; ArgentinaFil: Vila, Alejandro Jose. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Biología Molecular y Celular de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario; ArgentinaFil: Viale, Alejandro Miguel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Biología Molecular y Celular de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario; ArgentinaFil: Bermejo Morales, K.. Instituto Nacional de Enfermedades Respiratorias; MéxicoFil: Limansky, Adriana Sara. No especifíca;Wiley Blackwell Publishing, Inc2010-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/278097Quinones Falconi, F.; Galicia Velasco, M.; Marchiaro, P.; Mussi, María Alejandra; Ballerini, V.; et al.; Emergence of Pseudomonas aeruginosa strains producing metallo-β-lactamases of the IMP-15 and VIM-2 types in Mexico; Wiley Blackwell Publishing, Inc; Clinical Microbiology And Infection; 16; 2; 12-2010; 126-1311198-743XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://onlinelibrary.wiley.com/doi/10.1111/j.1469-0691.2009.02780.x/fullinfo:eu-repo/semantics/altIdentifier/doi/10.1111/j.1469-0691.2009.02780.xinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-12-23T14:13:21Zoai:ri.conicet.gov.ar:11336/278097instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-12-23 14:13:22.217CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
| dc.title.none.fl_str_mv |
Emergence of Pseudomonas aeruginosa strains producing metallo-β-lactamases of the IMP-15 and VIM-2 types in Mexico |
| title |
Emergence of Pseudomonas aeruginosa strains producing metallo-β-lactamases of the IMP-15 and VIM-2 types in Mexico |
| spellingShingle |
Emergence of Pseudomonas aeruginosa strains producing metallo-β-lactamases of the IMP-15 and VIM-2 types in Mexico Quinones Falconi, F. Metalo-B-lactamasas IMP-15 VIM-2 |
| title_short |
Emergence of Pseudomonas aeruginosa strains producing metallo-β-lactamases of the IMP-15 and VIM-2 types in Mexico |
| title_full |
Emergence of Pseudomonas aeruginosa strains producing metallo-β-lactamases of the IMP-15 and VIM-2 types in Mexico |
| title_fullStr |
Emergence of Pseudomonas aeruginosa strains producing metallo-β-lactamases of the IMP-15 and VIM-2 types in Mexico |
| title_full_unstemmed |
Emergence of Pseudomonas aeruginosa strains producing metallo-β-lactamases of the IMP-15 and VIM-2 types in Mexico |
| title_sort |
Emergence of Pseudomonas aeruginosa strains producing metallo-β-lactamases of the IMP-15 and VIM-2 types in Mexico |
| dc.creator.none.fl_str_mv |
Quinones Falconi, F. Galicia Velasco, M. Marchiaro, P. Mussi, María Alejandra Ballerini, V. Vila, Alejandro Jose Viale, Alejandro Miguel Bermejo Morales, K. Limansky, Adriana Sara |
| author |
Quinones Falconi, F. |
| author_facet |
Quinones Falconi, F. Galicia Velasco, M. Marchiaro, P. Mussi, María Alejandra Ballerini, V. Vila, Alejandro Jose Viale, Alejandro Miguel Bermejo Morales, K. Limansky, Adriana Sara |
| author_role |
author |
| author2 |
Galicia Velasco, M. Marchiaro, P. Mussi, María Alejandra Ballerini, V. Vila, Alejandro Jose Viale, Alejandro Miguel Bermejo Morales, K. Limansky, Adriana Sara |
| author2_role |
author author author author author author author author |
| dc.subject.none.fl_str_mv |
Metalo-B-lactamasas IMP-15 VIM-2 |
| topic |
Metalo-B-lactamasas IMP-15 VIM-2 |
| purl_subject.fl_str_mv |
https://purl.org/becyt/ford/3.3 https://purl.org/becyt/ford/3 |
| dc.description.none.fl_txt_mv |
Eighty-six carbapenem non-susceptible Pseudomonas aeruginosa isolates collected in the National Institute of Respiratory Diseases of Mexico City were screened for the presence of metallo-beta-lactamase (MBL) activity using both E-test strips and a microbiological assay with EDTA-imipenem. Genomic comparisons and sequence analyses conducted with these isolates revealed the presence of bla(VIM-2) in two clonally related isolates, and bla(IMP-15) in a clonally unrelated isolate. Both genes were found to be carried by class 1 integrons, and bla(IMP-15) was additionally present on a broad host-range plasmid. This is the first report of co-existing P. aeruginosa strains producing different MBLs in a Mexican hospital, highlighting the necessity of appropriate surveillance to prevent dissemination of carbapenem resistance. Fil: Quinones Falconi, F.. Instituto Nacional de Enfermedades Respiratorias; México Fil: Galicia Velasco, M.. Instituto Nacional de Enfermedades Respiratorias; México Fil: Marchiaro, P.. No especifíca; Fil: Mussi, María Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Centro de Estudios Fotosintéticos y Bioquímicos. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Centro de Estudios Fotosintéticos y Bioquímicos; Argentina Fil: Ballerini, V.. Hospital Intendente Carrasco; Argentina Fil: Vila, Alejandro Jose. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Biología Molecular y Celular de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario; Argentina Fil: Viale, Alejandro Miguel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Biología Molecular y Celular de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Biología Molecular y Celular de Rosario; Argentina Fil: Bermejo Morales, K.. Instituto Nacional de Enfermedades Respiratorias; México Fil: Limansky, Adriana Sara. No especifíca; |
| description |
Eighty-six carbapenem non-susceptible Pseudomonas aeruginosa isolates collected in the National Institute of Respiratory Diseases of Mexico City were screened for the presence of metallo-beta-lactamase (MBL) activity using both E-test strips and a microbiological assay with EDTA-imipenem. Genomic comparisons and sequence analyses conducted with these isolates revealed the presence of bla(VIM-2) in two clonally related isolates, and bla(IMP-15) in a clonally unrelated isolate. Both genes were found to be carried by class 1 integrons, and bla(IMP-15) was additionally present on a broad host-range plasmid. This is the first report of co-existing P. aeruginosa strains producing different MBLs in a Mexican hospital, highlighting the necessity of appropriate surveillance to prevent dissemination of carbapenem resistance. |
| publishDate |
2010 |
| dc.date.none.fl_str_mv |
2010-12 |
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info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
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article |
| status_str |
publishedVersion |
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http://hdl.handle.net/11336/278097 Quinones Falconi, F.; Galicia Velasco, M.; Marchiaro, P.; Mussi, María Alejandra; Ballerini, V.; et al.; Emergence of Pseudomonas aeruginosa strains producing metallo-β-lactamases of the IMP-15 and VIM-2 types in Mexico; Wiley Blackwell Publishing, Inc; Clinical Microbiology And Infection; 16; 2; 12-2010; 126-131 1198-743X CONICET Digital CONICET |
| url |
http://hdl.handle.net/11336/278097 |
| identifier_str_mv |
Quinones Falconi, F.; Galicia Velasco, M.; Marchiaro, P.; Mussi, María Alejandra; Ballerini, V.; et al.; Emergence of Pseudomonas aeruginosa strains producing metallo-β-lactamases of the IMP-15 and VIM-2 types in Mexico; Wiley Blackwell Publishing, Inc; Clinical Microbiology And Infection; 16; 2; 12-2010; 126-131 1198-743X CONICET Digital CONICET |
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eng |
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eng |
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