Evolution of the efficacy of a combined moxidectin-levamisole treatment against resistant gastrointestinal nematodes in lambs

Autores
Luque, Sonia Elisabet; Lloberas, Maria Mercedes; Cardozo, Patricia Alejandra; Lanusse, Carlos Edmundo; Virkel, Guillermo Leon; Farias, Cristina Elena; Viviani, Paula; Lifschitz, Adrian Luis; Alvarez, Luis Ignacio
Año de publicación
2019
Idioma
inglés
Tipo de recurso
documento de conferencia
Estado
versión publicada
Descripción
Nematodicidal combinations can be a valid strategy to achieve effective nematode control in thepresence of drug resistance. The aim of the current trial was to evaluate the pharmaco-parasitological outcome after the continuous use of moxidectin (MXD) and levamisole (LEV) as acombined treatment in lambs naturally parasitized with ivermectin-resistant gastrointestinalnematodes. Forty (40) lambs were divided into four groups (n=10): untreated control andsubcutaneously treated with either MXD (0.2 mg/kg), LEV (8 mg/kg) or with MXD+LEV (0.2and 8 mg/kg, respectively). Blood samples were collected at different times up to 1 (LEV) or 14(MXD) days post-treatment. LEV and MXD plasma concentrations were measured byHPLC. Faecal samples were collected on days 0, 7, and 14 post-treatment to perform the faecalegg count reduction tests (FECRT). No significant pharmacokinetic (PK) adverse changes wereobserved for either MXD or LEV after their co-administration in sheep. The clinical efficacy ofthe MXD+LEV combination was evaluated after its continuous use (3 treatments/year) over five(5) years at the same farm. The initial anthelmintic efficacies (1 st year) were 99% (MXD), 85%(LEV) and 100% (MXD+LEV). Following repeated annual treatments over five years, theclinical response for the combined treatment reached 87% efficacy. The combination reachedefficacies of 100% (1 st year) and 98.5% (5 th year) against Haemonchus contortus. Teladorsagia spp. and Trichostrongylus spp. were the main nematode genera surviving theindividual and combined treatments. The co-administration of MXD+LEV during five yearsresulted in a significant higher anthelmintic effect compared to MXD or LEV given alone. Evenwhen MXD and LEV individual efficacies were reduced during the five-year period, thecombined treatment maintains acceptable efficacy levels against H. contortus.
Fil: Luque, Sonia Elisabet. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina
Fil: Lloberas, Maria Mercedes. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Buenos Aires Sur. Estación Experimental Agropecuaria Balcarce. Agencia de Extensión Rural Balcarce; Argentina
Fil: Cardozo, Patricia Alejandra. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Buenos Aires Sur. Estación Experimental Agropecuaria Balcarce. Agencia de Extensión Rural Balcarce; Argentina
Fil: Lanusse, Carlos Edmundo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina
Fil: Virkel, Guillermo Leon. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina
Fil: Farias, Cristina Elena. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina
Fil: Viviani, Paula. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina
Fil: Lifschitz, Adrian Luis. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina
Fil: Alvarez, Luis Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina
27th Conference of the World Association for the Advancement of Veterinary Parasitology
Wisconsin
Estados Unidos
World Association for the Advancement of Veterinary Parasitology
Materia
Moxidectin
Levamisole
Resistant Gastrointestinal Nematodes
Lambs
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/169431
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/169431
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Evolution of the efficacy of a combined moxidectin-levamisole treatment against resistant gastrointestinal nematodes in lambsLuque, Sonia ElisabetLloberas, Maria MercedesCardozo, Patricia AlejandraLanusse, Carlos EdmundoVirkel, Guillermo LeonFarias, Cristina ElenaViviani, PaulaLifschitz, Adrian LuisAlvarez, Luis IgnacioMoxidectinLevamisoleResistant Gastrointestinal NematodesLambshttps://purl.org/becyt/ford/4.3https://purl.org/becyt/ford/4Nematodicidal combinations can be a valid strategy to achieve effective nematode control in thepresence of drug resistance. The aim of the current trial was to evaluate the pharmaco-parasitological outcome after the continuous use of moxidectin (MXD) and levamisole (LEV) as acombined treatment in lambs naturally parasitized with ivermectin-resistant gastrointestinalnematodes. Forty (40) lambs were divided into four groups (n=10): untreated control andsubcutaneously treated with either MXD (0.2 mg/kg), LEV (8 mg/kg) or with MXD+LEV (0.2and 8 mg/kg, respectively). Blood samples were collected at different times up to 1 (LEV) or 14(MXD) days post-treatment. LEV and MXD plasma concentrations were measured byHPLC. Faecal samples were collected on days 0, 7, and 14 post-treatment to perform the faecalegg count reduction tests (FECRT). No significant pharmacokinetic (PK) adverse changes wereobserved for either MXD or LEV after their co-administration in sheep. The clinical efficacy ofthe MXD+LEV combination was evaluated after its continuous use (3 treatments/year) over five(5) years at the same farm. The initial anthelmintic efficacies (1 st year) were 99% (MXD), 85%(LEV) and 100% (MXD+LEV). Following repeated annual treatments over five years, theclinical response for the combined treatment reached 87% efficacy. The combination reachedefficacies of 100% (1 st year) and 98.5% (5 th year) against Haemonchus contortus. Teladorsagia spp. and Trichostrongylus spp. were the main nematode genera surviving theindividual and combined treatments. The co-administration of MXD+LEV during five yearsresulted in a significant higher anthelmintic effect compared to MXD or LEV given alone. Evenwhen MXD and LEV individual efficacies were reduced during the five-year period, thecombined treatment maintains acceptable efficacy levels against H. contortus.Fil: Luque, Sonia Elisabet. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; ArgentinaFil: Lloberas, Maria Mercedes. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Buenos Aires Sur. Estación Experimental Agropecuaria Balcarce. Agencia de Extensión Rural Balcarce; ArgentinaFil: Cardozo, Patricia Alejandra. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Buenos Aires Sur. Estación Experimental Agropecuaria Balcarce. Agencia de Extensión Rural Balcarce; ArgentinaFil: Lanusse, Carlos Edmundo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; ArgentinaFil: Virkel, Guillermo Leon. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; ArgentinaFil: Farias, Cristina Elena. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; ArgentinaFil: Viviani, Paula. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; ArgentinaFil: Lifschitz, Adrian Luis. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; ArgentinaFil: Alvarez, Luis Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina27th Conference of the World Association for the Advancement of Veterinary ParasitologyWisconsinEstados UnidosWorld Association for the Advancement of Veterinary ParasitologyWorld Association of the Advancement of Veterinary Parasitology2019info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectConferenciaBookhttp://purl.org/coar/resource_type/c_5794info:ar-repo/semantics/documentoDeConferenciaapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/169431Evolution of the efficacy of a combined moxidectin-levamisole treatment against resistant gastrointestinal nematodes in lambs; 27th Conference of the World Association for the Advancement of Veterinary Parasitology; Wisconsin; Estados Unidos; 2019; 320-321CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.waavp2019.com/wp-content/uploads/2019/07/WAAVP2019-Abstract-Book.pdfInternacionalinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-03T09:44:02Zoai:ri.conicet.gov.ar:11336/169431instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-03 09:44:02.975CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Evolution of the efficacy of a combined moxidectin-levamisole treatment against resistant gastrointestinal nematodes in lambs
title Evolution of the efficacy of a combined moxidectin-levamisole treatment against resistant gastrointestinal nematodes in lambs
spellingShingle Evolution of the efficacy of a combined moxidectin-levamisole treatment against resistant gastrointestinal nematodes in lambs
Luque, Sonia Elisabet
Moxidectin
Levamisole
Resistant Gastrointestinal Nematodes
Lambs
title_short Evolution of the efficacy of a combined moxidectin-levamisole treatment against resistant gastrointestinal nematodes in lambs
title_full Evolution of the efficacy of a combined moxidectin-levamisole treatment against resistant gastrointestinal nematodes in lambs
title_fullStr Evolution of the efficacy of a combined moxidectin-levamisole treatment against resistant gastrointestinal nematodes in lambs
title_full_unstemmed Evolution of the efficacy of a combined moxidectin-levamisole treatment against resistant gastrointestinal nematodes in lambs
title_sort Evolution of the efficacy of a combined moxidectin-levamisole treatment against resistant gastrointestinal nematodes in lambs
dc.creator.none.fl_str_mv Luque, Sonia Elisabet
Lloberas, Maria Mercedes
Cardozo, Patricia Alejandra
Lanusse, Carlos Edmundo
Virkel, Guillermo Leon
Farias, Cristina Elena
Viviani, Paula
Lifschitz, Adrian Luis
Alvarez, Luis Ignacio
author Luque, Sonia Elisabet
author_facet Luque, Sonia Elisabet
Lloberas, Maria Mercedes
Cardozo, Patricia Alejandra
Lanusse, Carlos Edmundo
Virkel, Guillermo Leon
Farias, Cristina Elena
Viviani, Paula
Lifschitz, Adrian Luis
Alvarez, Luis Ignacio
author_role author
author2 Lloberas, Maria Mercedes
Cardozo, Patricia Alejandra
Lanusse, Carlos Edmundo
Virkel, Guillermo Leon
Farias, Cristina Elena
Viviani, Paula
Lifschitz, Adrian Luis
Alvarez, Luis Ignacio
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Moxidectin
Levamisole
Resistant Gastrointestinal Nematodes
Lambs
topic Moxidectin
Levamisole
Resistant Gastrointestinal Nematodes
Lambs
purl_subject.fl_str_mv https://purl.org/becyt/ford/4.3
https://purl.org/becyt/ford/4
dc.description.none.fl_txt_mv Nematodicidal combinations can be a valid strategy to achieve effective nematode control in thepresence of drug resistance. The aim of the current trial was to evaluate the pharmaco-parasitological outcome after the continuous use of moxidectin (MXD) and levamisole (LEV) as acombined treatment in lambs naturally parasitized with ivermectin-resistant gastrointestinalnematodes. Forty (40) lambs were divided into four groups (n=10): untreated control andsubcutaneously treated with either MXD (0.2 mg/kg), LEV (8 mg/kg) or with MXD+LEV (0.2and 8 mg/kg, respectively). Blood samples were collected at different times up to 1 (LEV) or 14(MXD) days post-treatment. LEV and MXD plasma concentrations were measured byHPLC. Faecal samples were collected on days 0, 7, and 14 post-treatment to perform the faecalegg count reduction tests (FECRT). No significant pharmacokinetic (PK) adverse changes wereobserved for either MXD or LEV after their co-administration in sheep. The clinical efficacy ofthe MXD+LEV combination was evaluated after its continuous use (3 treatments/year) over five(5) years at the same farm. The initial anthelmintic efficacies (1 st year) were 99% (MXD), 85%(LEV) and 100% (MXD+LEV). Following repeated annual treatments over five years, theclinical response for the combined treatment reached 87% efficacy. The combination reachedefficacies of 100% (1 st year) and 98.5% (5 th year) against Haemonchus contortus. Teladorsagia spp. and Trichostrongylus spp. were the main nematode genera surviving theindividual and combined treatments. The co-administration of MXD+LEV during five yearsresulted in a significant higher anthelmintic effect compared to MXD or LEV given alone. Evenwhen MXD and LEV individual efficacies were reduced during the five-year period, thecombined treatment maintains acceptable efficacy levels against H. contortus.
Fil: Luque, Sonia Elisabet. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina
Fil: Lloberas, Maria Mercedes. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Buenos Aires Sur. Estación Experimental Agropecuaria Balcarce. Agencia de Extensión Rural Balcarce; Argentina
Fil: Cardozo, Patricia Alejandra. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Buenos Aires Sur. Estación Experimental Agropecuaria Balcarce. Agencia de Extensión Rural Balcarce; Argentina
Fil: Lanusse, Carlos Edmundo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina
Fil: Virkel, Guillermo Leon. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina
Fil: Farias, Cristina Elena. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina
Fil: Viviani, Paula. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina
Fil: Lifschitz, Adrian Luis. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina
Fil: Alvarez, Luis Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina
27th Conference of the World Association for the Advancement of Veterinary Parasitology
Wisconsin
Estados Unidos
World Association for the Advancement of Veterinary Parasitology
description Nematodicidal combinations can be a valid strategy to achieve effective nematode control in thepresence of drug resistance. The aim of the current trial was to evaluate the pharmaco-parasitological outcome after the continuous use of moxidectin (MXD) and levamisole (LEV) as acombined treatment in lambs naturally parasitized with ivermectin-resistant gastrointestinalnematodes. Forty (40) lambs were divided into four groups (n=10): untreated control andsubcutaneously treated with either MXD (0.2 mg/kg), LEV (8 mg/kg) or with MXD+LEV (0.2and 8 mg/kg, respectively). Blood samples were collected at different times up to 1 (LEV) or 14(MXD) days post-treatment. LEV and MXD plasma concentrations were measured byHPLC. Faecal samples were collected on days 0, 7, and 14 post-treatment to perform the faecalegg count reduction tests (FECRT). No significant pharmacokinetic (PK) adverse changes wereobserved for either MXD or LEV after their co-administration in sheep. The clinical efficacy ofthe MXD+LEV combination was evaluated after its continuous use (3 treatments/year) over five(5) years at the same farm. The initial anthelmintic efficacies (1 st year) were 99% (MXD), 85%(LEV) and 100% (MXD+LEV). Following repeated annual treatments over five years, theclinical response for the combined treatment reached 87% efficacy. The combination reachedefficacies of 100% (1 st year) and 98.5% (5 th year) against Haemonchus contortus. Teladorsagia spp. and Trichostrongylus spp. were the main nematode genera surviving theindividual and combined treatments. The co-administration of MXD+LEV during five yearsresulted in a significant higher anthelmintic effect compared to MXD or LEV given alone. Evenwhen MXD and LEV individual efficacies were reduced during the five-year period, thecombined treatment maintains acceptable efficacy levels against H. contortus.
publishDate 2019
dc.date.none.fl_str_mv 2019
dc.type.none.fl_str_mv info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/conferenceObject
Conferencia
Book
http://purl.org/coar/resource_type/c_5794
info:ar-repo/semantics/documentoDeConferencia
status_str publishedVersion
format conferenceObject
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/169431
Evolution of the efficacy of a combined moxidectin-levamisole treatment against resistant gastrointestinal nematodes in lambs; 27th Conference of the World Association for the Advancement of Veterinary Parasitology; Wisconsin; Estados Unidos; 2019; 320-321
CONICET Digital
CONICET
url http://hdl.handle.net/11336/169431
identifier_str_mv Evolution of the efficacy of a combined moxidectin-levamisole treatment against resistant gastrointestinal nematodes in lambs; 27th Conference of the World Association for the Advancement of Veterinary Parasitology; Wisconsin; Estados Unidos; 2019; 320-321
CONICET Digital
CONICET
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language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.waavp2019.com/wp-content/uploads/2019/07/WAAVP2019-Abstract-Book.pdf
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rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
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dc.coverage.none.fl_str_mv Internacional
dc.publisher.none.fl_str_mv World Association of the Advancement of Veterinary Parasitology
publisher.none.fl_str_mv World Association of the Advancement of Veterinary Parasitology
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