Antimicrobial polymers: Antibacterial efficacy of silicone rubber–titanium dioxide composites

Autores
Felice, Betiana; Seitz, Vera; Bach, Maximilian; Rapp, Christin; Wintermantel, Erich
Año de publicación
2017
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Control and reduction of microorganism infections in high-risk environments is up to date a challenge. Traditional techniques imply several limitations including development of antibiotics resistance and ecotoxicity. Then, polymers functionalized with photocatalyts arise as a promising solution against a broad spectrum of microorganisms found at, e.g. sanitary, food, and medical environments. Here, we present silicone rubber–TiO2 composites as novel antibacterial polymers. Four different types of composites with different TiO2 contents were produced and analyzed under UV irradiation and dark conditions in terms of particle distribution, chemical composition, photocatalytic activity, wettability, and antibacterial efficacy against Escherichia coli. Under UV irradiation, antibacterial sensitivity assay showed a 1000 times reduction of colony forming units after 2 h of light exposure so that the antibacterial ability of silicone–TiO2 composites was proved. Photocatalytic activity assessment suggested that reactive oxygen species induced by photocatalytic reaction at TiO2 particles are the main cause of the observed antibacterial effect. Scanning electron microscopy indicated no topographical damage after UV exposure. In addition, chemical analysis through Raman and X-Ray photoelectron spectroscopies demonstrated the stability of the silicone matrix under UV irradiation. Hence, the current work presents silicone–TiO2 composites as stable nonspecific antibacterial polymers for prevention of infections at multiple high-risk environments.
Fil: Felice, Betiana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto Superior de Investigaciones Biológicas. Universidad Nacional de Tucumán. Instituto Superior de Investigaciones Biológicas; Argentina. Universidad Nacional de Tucumán. Facultad de Ciencias Exactas y Tecnología. Departamento de Bioingeniería. Laboratorio de Medios e Interfases; Argentina
Fil: Seitz, Vera. Technische Universitat Munchen; Alemania
Fil: Bach, Maximilian. Technische Universitat Munchen; Alemania
Fil: Rapp, Christin. Technische Universitat Munchen; Alemania
Fil: Wintermantel, Erich. Technische Universitat Munchen; Alemania
Materia
Antibacterial Activity
Antibacterial Polymers
Composites
Silicone Rubber
Titanium Dioxide (Tio2)
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/50609
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/50609
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Antimicrobial polymers: Antibacterial efficacy of silicone rubber–titanium dioxide compositesFelice, BetianaSeitz, VeraBach, MaximilianRapp, ChristinWintermantel, ErichAntibacterial ActivityAntibacterial PolymersCompositesSilicone RubberTitanium Dioxide (Tio2)https://purl.org/becyt/ford/2.5https://purl.org/becyt/ford/2https://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Control and reduction of microorganism infections in high-risk environments is up to date a challenge. Traditional techniques imply several limitations including development of antibiotics resistance and ecotoxicity. Then, polymers functionalized with photocatalyts arise as a promising solution against a broad spectrum of microorganisms found at, e.g. sanitary, food, and medical environments. Here, we present silicone rubber–TiO2 composites as novel antibacterial polymers. Four different types of composites with different TiO2 contents were produced and analyzed under UV irradiation and dark conditions in terms of particle distribution, chemical composition, photocatalytic activity, wettability, and antibacterial efficacy against Escherichia coli. Under UV irradiation, antibacterial sensitivity assay showed a 1000 times reduction of colony forming units after 2 h of light exposure so that the antibacterial ability of silicone–TiO2 composites was proved. Photocatalytic activity assessment suggested that reactive oxygen species induced by photocatalytic reaction at TiO2 particles are the main cause of the observed antibacterial effect. Scanning electron microscopy indicated no topographical damage after UV exposure. In addition, chemical analysis through Raman and X-Ray photoelectron spectroscopies demonstrated the stability of the silicone matrix under UV irradiation. Hence, the current work presents silicone–TiO2 composites as stable nonspecific antibacterial polymers for prevention of infections at multiple high-risk environments.Fil: Felice, Betiana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto Superior de Investigaciones Biológicas. Universidad Nacional de Tucumán. Instituto Superior de Investigaciones Biológicas; Argentina. Universidad Nacional de Tucumán. Facultad de Ciencias Exactas y Tecnología. Departamento de Bioingeniería. Laboratorio de Medios e Interfases; ArgentinaFil: Seitz, Vera. Technische Universitat Munchen; AlemaniaFil: Bach, Maximilian. Technische Universitat Munchen; AlemaniaFil: Rapp, Christin. Technische Universitat Munchen; AlemaniaFil: Wintermantel, Erich. Technische Universitat Munchen; AlemaniaSage Publications Ltd2017-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/50609Felice, Betiana; Seitz, Vera; Bach, Maximilian; Rapp, Christin; Wintermantel, Erich; Antimicrobial polymers: Antibacterial efficacy of silicone rubber–titanium dioxide composites; Sage Publications Ltd; Journal of Composite Materials; 51; 16; 7-2017; 2253-22620021-9983CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1177/0021998316668984info:eu-repo/semantics/altIdentifier/url/http://journals.sagepub.com/doi/10.1177/0021998316668984info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:36:52Zoai:ri.conicet.gov.ar:11336/50609instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:36:52.816CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Antimicrobial polymers: Antibacterial efficacy of silicone rubber–titanium dioxide composites
title Antimicrobial polymers: Antibacterial efficacy of silicone rubber–titanium dioxide composites
spellingShingle Antimicrobial polymers: Antibacterial efficacy of silicone rubber–titanium dioxide composites
Felice, Betiana
Antibacterial Activity
Antibacterial Polymers
Composites
Silicone Rubber
Titanium Dioxide (Tio2)
title_short Antimicrobial polymers: Antibacterial efficacy of silicone rubber–titanium dioxide composites
title_full Antimicrobial polymers: Antibacterial efficacy of silicone rubber–titanium dioxide composites
title_fullStr Antimicrobial polymers: Antibacterial efficacy of silicone rubber–titanium dioxide composites
title_full_unstemmed Antimicrobial polymers: Antibacterial efficacy of silicone rubber–titanium dioxide composites
title_sort Antimicrobial polymers: Antibacterial efficacy of silicone rubber–titanium dioxide composites
dc.creator.none.fl_str_mv Felice, Betiana
Seitz, Vera
Bach, Maximilian
Rapp, Christin
Wintermantel, Erich
author Felice, Betiana
author_facet Felice, Betiana
Seitz, Vera
Bach, Maximilian
Rapp, Christin
Wintermantel, Erich
author_role author
author2 Seitz, Vera
Bach, Maximilian
Rapp, Christin
Wintermantel, Erich
author2_role author
author
author
author
dc.subject.none.fl_str_mv Antibacterial Activity
Antibacterial Polymers
Composites
Silicone Rubber
Titanium Dioxide (Tio2)
topic Antibacterial Activity
Antibacterial Polymers
Composites
Silicone Rubber
Titanium Dioxide (Tio2)
purl_subject.fl_str_mv https://purl.org/becyt/ford/2.5
https://purl.org/becyt/ford/2
https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Control and reduction of microorganism infections in high-risk environments is up to date a challenge. Traditional techniques imply several limitations including development of antibiotics resistance and ecotoxicity. Then, polymers functionalized with photocatalyts arise as a promising solution against a broad spectrum of microorganisms found at, e.g. sanitary, food, and medical environments. Here, we present silicone rubber–TiO2 composites as novel antibacterial polymers. Four different types of composites with different TiO2 contents were produced and analyzed under UV irradiation and dark conditions in terms of particle distribution, chemical composition, photocatalytic activity, wettability, and antibacterial efficacy against Escherichia coli. Under UV irradiation, antibacterial sensitivity assay showed a 1000 times reduction of colony forming units after 2 h of light exposure so that the antibacterial ability of silicone–TiO2 composites was proved. Photocatalytic activity assessment suggested that reactive oxygen species induced by photocatalytic reaction at TiO2 particles are the main cause of the observed antibacterial effect. Scanning electron microscopy indicated no topographical damage after UV exposure. In addition, chemical analysis through Raman and X-Ray photoelectron spectroscopies demonstrated the stability of the silicone matrix under UV irradiation. Hence, the current work presents silicone–TiO2 composites as stable nonspecific antibacterial polymers for prevention of infections at multiple high-risk environments.
Fil: Felice, Betiana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Instituto Superior de Investigaciones Biológicas. Universidad Nacional de Tucumán. Instituto Superior de Investigaciones Biológicas; Argentina. Universidad Nacional de Tucumán. Facultad de Ciencias Exactas y Tecnología. Departamento de Bioingeniería. Laboratorio de Medios e Interfases; Argentina
Fil: Seitz, Vera. Technische Universitat Munchen; Alemania
Fil: Bach, Maximilian. Technische Universitat Munchen; Alemania
Fil: Rapp, Christin. Technische Universitat Munchen; Alemania
Fil: Wintermantel, Erich. Technische Universitat Munchen; Alemania
description Control and reduction of microorganism infections in high-risk environments is up to date a challenge. Traditional techniques imply several limitations including development of antibiotics resistance and ecotoxicity. Then, polymers functionalized with photocatalyts arise as a promising solution against a broad spectrum of microorganisms found at, e.g. sanitary, food, and medical environments. Here, we present silicone rubber–TiO2 composites as novel antibacterial polymers. Four different types of composites with different TiO2 contents were produced and analyzed under UV irradiation and dark conditions in terms of particle distribution, chemical composition, photocatalytic activity, wettability, and antibacterial efficacy against Escherichia coli. Under UV irradiation, antibacterial sensitivity assay showed a 1000 times reduction of colony forming units after 2 h of light exposure so that the antibacterial ability of silicone–TiO2 composites was proved. Photocatalytic activity assessment suggested that reactive oxygen species induced by photocatalytic reaction at TiO2 particles are the main cause of the observed antibacterial effect. Scanning electron microscopy indicated no topographical damage after UV exposure. In addition, chemical analysis through Raman and X-Ray photoelectron spectroscopies demonstrated the stability of the silicone matrix under UV irradiation. Hence, the current work presents silicone–TiO2 composites as stable nonspecific antibacterial polymers for prevention of infections at multiple high-risk environments.
publishDate 2017
dc.date.none.fl_str_mv 2017-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/50609
Felice, Betiana; Seitz, Vera; Bach, Maximilian; Rapp, Christin; Wintermantel, Erich; Antimicrobial polymers: Antibacterial efficacy of silicone rubber–titanium dioxide composites; Sage Publications Ltd; Journal of Composite Materials; 51; 16; 7-2017; 2253-2262
0021-9983
CONICET Digital
CONICET
url http://hdl.handle.net/11336/50609
identifier_str_mv Felice, Betiana; Seitz, Vera; Bach, Maximilian; Rapp, Christin; Wintermantel, Erich; Antimicrobial polymers: Antibacterial efficacy of silicone rubber–titanium dioxide composites; Sage Publications Ltd; Journal of Composite Materials; 51; 16; 7-2017; 2253-2262
0021-9983
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1177/0021998316668984
info:eu-repo/semantics/altIdentifier/url/http://journals.sagepub.com/doi/10.1177/0021998316668984
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Sage Publications Ltd
publisher.none.fl_str_mv Sage Publications Ltd
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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