Lactobacillus fermentum CRL 722 is able to deliver active α-galactosidase activity in the small intestine of rats

Autores
Leblanc, Jean Guy Joseph; Piard, Jean-Christophe; Sesma, Fernando Juan Manuel; Savoy, Graciela
Año de publicación
2005
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
α-galactooligosaccharides (α-GOS) found in legumes such as soybeans can cause gastrointestinal disorders since mammals lack α-galactosidase (α-Gal) in the small intestine which is necessary for their hydrolysis. Lactobacillus fermentum CRL 722 is a lactic acid bacterium (LAB) capable of degrading α-GOS due to its elevated α-Gal activity. When conventional rats were fed live L. fermentum CRL 722 or cell-free extracts of this strain, a short-lived α-Gal activity was detected in the upper gastrointestinal tract. The safety of this LAB was also assessed. L. fermentum CRL 722 could thus be used as a vehicle to safely confer α-Gal in the small intestine of monogastric animal.
Fil: Leblanc, Jean Guy Joseph. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; Argentina
Fil: Piard, Jean-Christophe. Institut National de la Recherche Agronomique; Francia
Fil: Sesma, Fernando Juan Manuel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; Argentina
Fil: Savoy, Graciela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; Argentina. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia; Argentina
Materia
Α-Galactosidase
Α-Gos
Flatulence
Gut
Lactic Acid Bacteria
Soymilk
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/58823
Acceder
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network_acronym_str CONICETDig
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network_name_str CONICET Digital (CONICET)
spelling Lactobacillus fermentum CRL 722 is able to deliver active α-galactosidase activity in the small intestine of ratsLeblanc, Jean Guy JosephPiard, Jean-ChristopheSesma, Fernando Juan ManuelSavoy, GracielaΑ-GalactosidaseΑ-GosFlatulenceGutLactic Acid BacteriaSoymilkα-galactooligosaccharides (α-GOS) found in legumes such as soybeans can cause gastrointestinal disorders since mammals lack α-galactosidase (α-Gal) in the small intestine which is necessary for their hydrolysis. Lactobacillus fermentum CRL 722 is a lactic acid bacterium (LAB) capable of degrading α-GOS due to its elevated α-Gal activity. When conventional rats were fed live L. fermentum CRL 722 or cell-free extracts of this strain, a short-lived α-Gal activity was detected in the upper gastrointestinal tract. The safety of this LAB was also assessed. L. fermentum CRL 722 could thus be used as a vehicle to safely confer α-Gal in the small intestine of monogastric animal.Fil: Leblanc, Jean Guy Joseph. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; ArgentinaFil: Piard, Jean-Christophe. Institut National de la Recherche Agronomique; FranciaFil: Sesma, Fernando Juan Manuel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; ArgentinaFil: Savoy, Graciela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; Argentina. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia; ArgentinaOxford University Press2005-07-15info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/58823Leblanc, Jean Guy Joseph; Piard, Jean-Christophe; Sesma, Fernando Juan Manuel; Savoy, Graciela; Lactobacillus fermentum CRL 722 is able to deliver active α-galactosidase activity in the small intestine of rats; Oxford University Press; FEMS Microbiology Letters; 248; 2; 15-7-2005; 177-1820378-10971574-6968CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/doi/10.1016/j.femsle.2005.05.054info:eu-repo/semantics/altIdentifier/url/https://academic.oup.com/femsle/article/248/2/177/522551info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:13:52Zoai:ri.conicet.gov.ar:11336/58823instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:13:52.29CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Lactobacillus fermentum CRL 722 is able to deliver active α-galactosidase activity in the small intestine of rats
title Lactobacillus fermentum CRL 722 is able to deliver active α-galactosidase activity in the small intestine of rats
spellingShingle Lactobacillus fermentum CRL 722 is able to deliver active α-galactosidase activity in the small intestine of rats
Leblanc, Jean Guy Joseph
Α-Galactosidase
Α-Gos
Flatulence
Gut
Lactic Acid Bacteria
Soymilk
title_short Lactobacillus fermentum CRL 722 is able to deliver active α-galactosidase activity in the small intestine of rats
title_full Lactobacillus fermentum CRL 722 is able to deliver active α-galactosidase activity in the small intestine of rats
title_fullStr Lactobacillus fermentum CRL 722 is able to deliver active α-galactosidase activity in the small intestine of rats
title_full_unstemmed Lactobacillus fermentum CRL 722 is able to deliver active α-galactosidase activity in the small intestine of rats
title_sort Lactobacillus fermentum CRL 722 is able to deliver active α-galactosidase activity in the small intestine of rats
dc.creator.none.fl_str_mv Leblanc, Jean Guy Joseph
Piard, Jean-Christophe
Sesma, Fernando Juan Manuel
Savoy, Graciela
author Leblanc, Jean Guy Joseph
author_facet Leblanc, Jean Guy Joseph
Piard, Jean-Christophe
Sesma, Fernando Juan Manuel
Savoy, Graciela
author_role author
author2 Piard, Jean-Christophe
Sesma, Fernando Juan Manuel
Savoy, Graciela
author2_role author
author
author
dc.subject.none.fl_str_mv Α-Galactosidase
Α-Gos
Flatulence
Gut
Lactic Acid Bacteria
Soymilk
topic Α-Galactosidase
Α-Gos
Flatulence
Gut
Lactic Acid Bacteria
Soymilk
dc.description.none.fl_txt_mv α-galactooligosaccharides (α-GOS) found in legumes such as soybeans can cause gastrointestinal disorders since mammals lack α-galactosidase (α-Gal) in the small intestine which is necessary for their hydrolysis. Lactobacillus fermentum CRL 722 is a lactic acid bacterium (LAB) capable of degrading α-GOS due to its elevated α-Gal activity. When conventional rats were fed live L. fermentum CRL 722 or cell-free extracts of this strain, a short-lived α-Gal activity was detected in the upper gastrointestinal tract. The safety of this LAB was also assessed. L. fermentum CRL 722 could thus be used as a vehicle to safely confer α-Gal in the small intestine of monogastric animal.
Fil: Leblanc, Jean Guy Joseph. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; Argentina
Fil: Piard, Jean-Christophe. Institut National de la Recherche Agronomique; Francia
Fil: Sesma, Fernando Juan Manuel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; Argentina
Fil: Savoy, Graciela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; Argentina. Universidad Nacional de Tucumán. Facultad de Bioquímica, Química y Farmacia; Argentina
description α-galactooligosaccharides (α-GOS) found in legumes such as soybeans can cause gastrointestinal disorders since mammals lack α-galactosidase (α-Gal) in the small intestine which is necessary for their hydrolysis. Lactobacillus fermentum CRL 722 is a lactic acid bacterium (LAB) capable of degrading α-GOS due to its elevated α-Gal activity. When conventional rats were fed live L. fermentum CRL 722 or cell-free extracts of this strain, a short-lived α-Gal activity was detected in the upper gastrointestinal tract. The safety of this LAB was also assessed. L. fermentum CRL 722 could thus be used as a vehicle to safely confer α-Gal in the small intestine of monogastric animal.
publishDate 2005
dc.date.none.fl_str_mv 2005-07-15
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/58823
Leblanc, Jean Guy Joseph; Piard, Jean-Christophe; Sesma, Fernando Juan Manuel; Savoy, Graciela; Lactobacillus fermentum CRL 722 is able to deliver active α-galactosidase activity in the small intestine of rats; Oxford University Press; FEMS Microbiology Letters; 248; 2; 15-7-2005; 177-182
0378-1097
1574-6968
CONICET Digital
CONICET
url http://hdl.handle.net/11336/58823
identifier_str_mv Leblanc, Jean Guy Joseph; Piard, Jean-Christophe; Sesma, Fernando Juan Manuel; Savoy, Graciela; Lactobacillus fermentum CRL 722 is able to deliver active α-galactosidase activity in the small intestine of rats; Oxford University Press; FEMS Microbiology Letters; 248; 2; 15-7-2005; 177-182
0378-1097
1574-6968
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/doi/10.1016/j.femsle.2005.05.054
info:eu-repo/semantics/altIdentifier/url/https://academic.oup.com/femsle/article/248/2/177/522551
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Oxford University Press
publisher.none.fl_str_mv Oxford University Press
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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