Lipidic nanoparticules: a model function to predict the transition temperature of DPPC-DMPC mixtures

Autores
Buffo, Flavia Edith; Sierra, Maria Belen; Pedroni, Viviana Isabel; Morini, Marcela Ana
Año de publicación
2017
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Thermotropic behavior of unilamellar liposomes prepared from binary mixtures of phosphatidylcholines in aqueous suspensions was analyzed by means of the temperature dependence of the Zeta Potential (ZP). This technique presents high sensitivity and small amount of sample required, that is, 70% less than that required in the use of conventional calorimeters. A model function is proposed to adjust the thermotropic behavior of the DPPC-DMPC system. From the adjustment, temperature transition (Ttransition) data as a function of the composition are obtained. The objective of this paper is to propose, from those few Ttransition-composition data, a function that allows obtaining Ttransition for any composition of the mentioned system. Moreover, graph of phase boundaries for these mixed-lipid vesicles was constructed by plotting the delimiting temperatures of the main phase transition as a function of the lipid composition of the vesicle. The combination of the zeta potential technique and the mathematical processing of their data would be a simple and useful tool for determining the transition temperatures of more complex mixtures.
Fil: Buffo, Flavia Edith. Universidad Nacional del Sur. Departamento de Matemática; Argentina
Fil: Sierra, Maria Belen. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; Argentina
Fil: Pedroni, Viviana Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; Argentina
Fil: Morini, Marcela Ana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; Argentina
Materia
LIPID MIXTURES
UNILAMELLAR VESICLES
ZETA POTENTIAL
TRANSITION TEMPERATURES
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/56108
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Lipidic nanoparticules: a model function to predict the transition temperature of DPPC-DMPC mixturesBuffo, Flavia EdithSierra, Maria BelenPedroni, Viviana IsabelMorini, Marcela AnaLIPID MIXTURESUNILAMELLAR VESICLESZETA POTENTIALTRANSITION TEMPERATUREShttps://purl.org/becyt/ford/1.1https://purl.org/becyt/ford/1Thermotropic behavior of unilamellar liposomes prepared from binary mixtures of phosphatidylcholines in aqueous suspensions was analyzed by means of the temperature dependence of the Zeta Potential (ZP). This technique presents high sensitivity and small amount of sample required, that is, 70% less than that required in the use of conventional calorimeters. A model function is proposed to adjust the thermotropic behavior of the DPPC-DMPC system. From the adjustment, temperature transition (Ttransition) data as a function of the composition are obtained. The objective of this paper is to propose, from those few Ttransition-composition data, a function that allows obtaining Ttransition for any composition of the mentioned system. Moreover, graph of phase boundaries for these mixed-lipid vesicles was constructed by plotting the delimiting temperatures of the main phase transition as a function of the lipid composition of the vesicle. The combination of the zeta potential technique and the mathematical processing of their data would be a simple and useful tool for determining the transition temperatures of more complex mixtures.Fil: Buffo, Flavia Edith. Universidad Nacional del Sur. Departamento de Matemática; ArgentinaFil: Sierra, Maria Belen. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; ArgentinaFil: Pedroni, Viviana Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; ArgentinaFil: Morini, Marcela Ana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; ArgentinaOpen Access Text2017-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/56108Buffo, Flavia Edith; Sierra, Maria Belen; Pedroni, Viviana Isabel; Morini, Marcela Ana; Lipidic nanoparticules: a model function to predict the transition temperature of DPPC-DMPC mixtures; Open Access Text; Advanced Material Science; 2; 1; 3-2017; 1-62398-6883CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/http://www.oatext.com/Lipidic-nanoparticules-a-model-function-to-predict-the-transition-temperature-of-DPPC-DMPC-mixtures.phpinfo:eu-repo/semantics/altIdentifier/doi/10.15761/AMS.1000117info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:37:55Zoai:ri.conicet.gov.ar:11336/56108instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:37:56.059CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Lipidic nanoparticules: a model function to predict the transition temperature of DPPC-DMPC mixtures
title Lipidic nanoparticules: a model function to predict the transition temperature of DPPC-DMPC mixtures
spellingShingle Lipidic nanoparticules: a model function to predict the transition temperature of DPPC-DMPC mixtures
Buffo, Flavia Edith
LIPID MIXTURES
UNILAMELLAR VESICLES
ZETA POTENTIAL
TRANSITION TEMPERATURES
title_short Lipidic nanoparticules: a model function to predict the transition temperature of DPPC-DMPC mixtures
title_full Lipidic nanoparticules: a model function to predict the transition temperature of DPPC-DMPC mixtures
title_fullStr Lipidic nanoparticules: a model function to predict the transition temperature of DPPC-DMPC mixtures
title_full_unstemmed Lipidic nanoparticules: a model function to predict the transition temperature of DPPC-DMPC mixtures
title_sort Lipidic nanoparticules: a model function to predict the transition temperature of DPPC-DMPC mixtures
dc.creator.none.fl_str_mv Buffo, Flavia Edith
Sierra, Maria Belen
Pedroni, Viviana Isabel
Morini, Marcela Ana
author Buffo, Flavia Edith
author_facet Buffo, Flavia Edith
Sierra, Maria Belen
Pedroni, Viviana Isabel
Morini, Marcela Ana
author_role author
author2 Sierra, Maria Belen
Pedroni, Viviana Isabel
Morini, Marcela Ana
author2_role author
author
author
dc.subject.none.fl_str_mv LIPID MIXTURES
UNILAMELLAR VESICLES
ZETA POTENTIAL
TRANSITION TEMPERATURES
topic LIPID MIXTURES
UNILAMELLAR VESICLES
ZETA POTENTIAL
TRANSITION TEMPERATURES
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.1
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Thermotropic behavior of unilamellar liposomes prepared from binary mixtures of phosphatidylcholines in aqueous suspensions was analyzed by means of the temperature dependence of the Zeta Potential (ZP). This technique presents high sensitivity and small amount of sample required, that is, 70% less than that required in the use of conventional calorimeters. A model function is proposed to adjust the thermotropic behavior of the DPPC-DMPC system. From the adjustment, temperature transition (Ttransition) data as a function of the composition are obtained. The objective of this paper is to propose, from those few Ttransition-composition data, a function that allows obtaining Ttransition for any composition of the mentioned system. Moreover, graph of phase boundaries for these mixed-lipid vesicles was constructed by plotting the delimiting temperatures of the main phase transition as a function of the lipid composition of the vesicle. The combination of the zeta potential technique and the mathematical processing of their data would be a simple and useful tool for determining the transition temperatures of more complex mixtures.
Fil: Buffo, Flavia Edith. Universidad Nacional del Sur. Departamento de Matemática; Argentina
Fil: Sierra, Maria Belen. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; Argentina
Fil: Pedroni, Viviana Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; Argentina
Fil: Morini, Marcela Ana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Química del Sur. Universidad Nacional del Sur. Departamento de Química. Instituto de Química del Sur; Argentina
description Thermotropic behavior of unilamellar liposomes prepared from binary mixtures of phosphatidylcholines in aqueous suspensions was analyzed by means of the temperature dependence of the Zeta Potential (ZP). This technique presents high sensitivity and small amount of sample required, that is, 70% less than that required in the use of conventional calorimeters. A model function is proposed to adjust the thermotropic behavior of the DPPC-DMPC system. From the adjustment, temperature transition (Ttransition) data as a function of the composition are obtained. The objective of this paper is to propose, from those few Ttransition-composition data, a function that allows obtaining Ttransition for any composition of the mentioned system. Moreover, graph of phase boundaries for these mixed-lipid vesicles was constructed by plotting the delimiting temperatures of the main phase transition as a function of the lipid composition of the vesicle. The combination of the zeta potential technique and the mathematical processing of their data would be a simple and useful tool for determining the transition temperatures of more complex mixtures.
publishDate 2017
dc.date.none.fl_str_mv 2017-03
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/56108
Buffo, Flavia Edith; Sierra, Maria Belen; Pedroni, Viviana Isabel; Morini, Marcela Ana; Lipidic nanoparticules: a model function to predict the transition temperature of DPPC-DMPC mixtures; Open Access Text; Advanced Material Science; 2; 1; 3-2017; 1-6
2398-6883
CONICET Digital
CONICET
url http://hdl.handle.net/11336/56108
identifier_str_mv Buffo, Flavia Edith; Sierra, Maria Belen; Pedroni, Viviana Isabel; Morini, Marcela Ana; Lipidic nanoparticules: a model function to predict the transition temperature of DPPC-DMPC mixtures; Open Access Text; Advanced Material Science; 2; 1; 3-2017; 1-6
2398-6883
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.oatext.com/Lipidic-nanoparticules-a-model-function-to-predict-the-transition-temperature-of-DPPC-DMPC-mixtures.php
info:eu-repo/semantics/altIdentifier/doi/10.15761/AMS.1000117
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Open Access Text
publisher.none.fl_str_mv Open Access Text
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.070432

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