Synthesis of multicyclic β-Lactam derivatives via solid-phase- generated ketenes
- Autores
- Mendez, Luciana; Mata, Ernesto Gabino
- Año de publicación
- 2010
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- An efficient approach for the solid-phase synthesis of multicyclic â-lactam derivatives is described. The key step is the cycloaddition reaction between an immobilized ketene and different cyclic imines to afford the corresponding benzofused carbacepham derivatives in high yield for the overall synthetic sequence.
Fil: Mendez, Luciana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Química Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario; Argentina
Fil: Mata, Ernesto Gabino. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Química Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario; Argentina - Materia
-
solid-phase synthesis
beta-lactam derivatives
staudinger cycloaddition - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
- Repositorio
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/127696
Ver los metadatos del registro completo
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Synthesis of multicyclic β-Lactam derivatives via solid-phase- generated ketenesMendez, LucianaMata, Ernesto Gabinosolid-phase synthesisbeta-lactam derivativesstaudinger cycloadditionhttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1An efficient approach for the solid-phase synthesis of multicyclic â-lactam derivatives is described. The key step is the cycloaddition reaction between an immobilized ketene and different cyclic imines to afford the corresponding benzofused carbacepham derivatives in high yield for the overall synthetic sequence.Fil: Mendez, Luciana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Química Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario; ArgentinaFil: Mata, Ernesto Gabino. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Química Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario; ArgentinaAmerican Chemical Society2010-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/127696Mendez, Luciana; Mata, Ernesto Gabino; Synthesis of multicyclic β-Lactam derivatives via solid-phase- generated ketenes; American Chemical Society; J. Comb. Chem.; 12; 6; 9-2010; 810-8131520-4766CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://pubs.acs.org/doi/10.1021/cc100140rinfo:eu-repo/semantics/altIdentifier/doi/10.1021/cc100140rinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T09:55:38Zoai:ri.conicet.gov.ar:11336/127696instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 09:55:38.973CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
dc.title.none.fl_str_mv |
Synthesis of multicyclic β-Lactam derivatives via solid-phase- generated ketenes |
title |
Synthesis of multicyclic β-Lactam derivatives via solid-phase- generated ketenes |
spellingShingle |
Synthesis of multicyclic β-Lactam derivatives via solid-phase- generated ketenes Mendez, Luciana solid-phase synthesis beta-lactam derivatives staudinger cycloaddition |
title_short |
Synthesis of multicyclic β-Lactam derivatives via solid-phase- generated ketenes |
title_full |
Synthesis of multicyclic β-Lactam derivatives via solid-phase- generated ketenes |
title_fullStr |
Synthesis of multicyclic β-Lactam derivatives via solid-phase- generated ketenes |
title_full_unstemmed |
Synthesis of multicyclic β-Lactam derivatives via solid-phase- generated ketenes |
title_sort |
Synthesis of multicyclic β-Lactam derivatives via solid-phase- generated ketenes |
dc.creator.none.fl_str_mv |
Mendez, Luciana Mata, Ernesto Gabino |
author |
Mendez, Luciana |
author_facet |
Mendez, Luciana Mata, Ernesto Gabino |
author_role |
author |
author2 |
Mata, Ernesto Gabino |
author2_role |
author |
dc.subject.none.fl_str_mv |
solid-phase synthesis beta-lactam derivatives staudinger cycloaddition |
topic |
solid-phase synthesis beta-lactam derivatives staudinger cycloaddition |
purl_subject.fl_str_mv |
https://purl.org/becyt/ford/1.4 https://purl.org/becyt/ford/1 |
dc.description.none.fl_txt_mv |
An efficient approach for the solid-phase synthesis of multicyclic â-lactam derivatives is described. The key step is the cycloaddition reaction between an immobilized ketene and different cyclic imines to afford the corresponding benzofused carbacepham derivatives in high yield for the overall synthetic sequence. Fil: Mendez, Luciana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Química Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario; Argentina Fil: Mata, Ernesto Gabino. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Química Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquímicas y Farmacéuticas. Instituto de Química Rosario; Argentina |
description |
An efficient approach for the solid-phase synthesis of multicyclic â-lactam derivatives is described. The key step is the cycloaddition reaction between an immobilized ketene and different cyclic imines to afford the corresponding benzofused carbacepham derivatives in high yield for the overall synthetic sequence. |
publishDate |
2010 |
dc.date.none.fl_str_mv |
2010-09 |
dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
format |
article |
status_str |
publishedVersion |
dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/127696 Mendez, Luciana; Mata, Ernesto Gabino; Synthesis of multicyclic β-Lactam derivatives via solid-phase- generated ketenes; American Chemical Society; J. Comb. Chem.; 12; 6; 9-2010; 810-813 1520-4766 CONICET Digital CONICET |
url |
http://hdl.handle.net/11336/127696 |
identifier_str_mv |
Mendez, Luciana; Mata, Ernesto Gabino; Synthesis of multicyclic β-Lactam derivatives via solid-phase- generated ketenes; American Chemical Society; J. Comb. Chem.; 12; 6; 9-2010; 810-813 1520-4766 CONICET Digital CONICET |
dc.language.none.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/url/https://pubs.acs.org/doi/10.1021/cc100140r info:eu-repo/semantics/altIdentifier/doi/10.1021/cc100140r |
dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
dc.format.none.fl_str_mv |
application/pdf application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
American Chemical Society |
publisher.none.fl_str_mv |
American Chemical Society |
dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
reponame_str |
CONICET Digital (CONICET) |
collection |
CONICET Digital (CONICET) |
instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
_version_ |
1844613676745621504 |
score |
13.070432 |