Chelation Therapies: A Chemical and Biochemical Perspective

Autores
Baran, Enrique José
Año de publicación
2010
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Chelation therapy occupies a central place in modern medicine and pharmacology, beacuse continuous studies with laboratory animals and extensive clinical experience demonstrate that accute or chronic intoxications with a variety of metals can be considerable improved by administration of a suitable chelating agent. In this review the chemical characteristics, properties and uses of the most common chelating agents as well as those of some new and very promising agents of this type, are discussed. In the second part of the review the biological and biochemical impact of these agents, as well as their use for the treatment of some selected diseases and disorders, are also analyzed and discussed in detail.
Fil: Baran, Enrique José. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Química Inorgánica "Dr. Pedro J. Aymonino". Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Química Inorgánica "Dr. Pedro J. Aymonino"; Argentina
Materia
TOXIC METALS
CHELATING AGENTS
CHEMICAL CHARACTERISTICS
BIOLOGICAL EFFECTS
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/103522
Acceder
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network_name_str CONICET Digital (CONICET)
spelling Chelation Therapies: A Chemical and Biochemical PerspectiveBaran, Enrique JoséTOXIC METALSCHELATING AGENTSCHEMICAL CHARACTERISTICSBIOLOGICAL EFFECTShttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1Chelation therapy occupies a central place in modern medicine and pharmacology, beacuse continuous studies with laboratory animals and extensive clinical experience demonstrate that accute or chronic intoxications with a variety of metals can be considerable improved by administration of a suitable chelating agent. In this review the chemical characteristics, properties and uses of the most common chelating agents as well as those of some new and very promising agents of this type, are discussed. In the second part of the review the biological and biochemical impact of these agents, as well as their use for the treatment of some selected diseases and disorders, are also analyzed and discussed in detail.Fil: Baran, Enrique José. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Química Inorgánica "Dr. Pedro J. Aymonino". Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Química Inorgánica "Dr. Pedro J. Aymonino"; ArgentinaBentham Science Publishers2010-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/103522Baran, Enrique José; Chelation Therapies: A Chemical and Biochemical Perspective; Bentham Science Publishers; Current Medicinal Chemistry; 17; 31; 11-2010; 3658-36720929-86731875-533XCONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pubmed/20846112info:eu-repo/semantics/altIdentifier/url/http://www.eurekaselect.com/72556/articleinfo:eu-repo/semantics/altIdentifier/doi/10.2174/092986710793213760info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:47:06Zoai:ri.conicet.gov.ar:11336/103522instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:47:06.389CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Chelation Therapies: A Chemical and Biochemical Perspective
title Chelation Therapies: A Chemical and Biochemical Perspective
spellingShingle Chelation Therapies: A Chemical and Biochemical Perspective
Baran, Enrique José
TOXIC METALS
CHELATING AGENTS
CHEMICAL CHARACTERISTICS
BIOLOGICAL EFFECTS
title_short Chelation Therapies: A Chemical and Biochemical Perspective
title_full Chelation Therapies: A Chemical and Biochemical Perspective
title_fullStr Chelation Therapies: A Chemical and Biochemical Perspective
title_full_unstemmed Chelation Therapies: A Chemical and Biochemical Perspective
title_sort Chelation Therapies: A Chemical and Biochemical Perspective
dc.creator.none.fl_str_mv Baran, Enrique José
author Baran, Enrique José
author_facet Baran, Enrique José
author_role author
dc.subject.none.fl_str_mv TOXIC METALS
CHELATING AGENTS
CHEMICAL CHARACTERISTICS
BIOLOGICAL EFFECTS
topic TOXIC METALS
CHELATING AGENTS
CHEMICAL CHARACTERISTICS
BIOLOGICAL EFFECTS
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Chelation therapy occupies a central place in modern medicine and pharmacology, beacuse continuous studies with laboratory animals and extensive clinical experience demonstrate that accute or chronic intoxications with a variety of metals can be considerable improved by administration of a suitable chelating agent. In this review the chemical characteristics, properties and uses of the most common chelating agents as well as those of some new and very promising agents of this type, are discussed. In the second part of the review the biological and biochemical impact of these agents, as well as their use for the treatment of some selected diseases and disorders, are also analyzed and discussed in detail.
Fil: Baran, Enrique José. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Química Inorgánica "Dr. Pedro J. Aymonino". Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Química Inorgánica "Dr. Pedro J. Aymonino"; Argentina
description Chelation therapy occupies a central place in modern medicine and pharmacology, beacuse continuous studies with laboratory animals and extensive clinical experience demonstrate that accute or chronic intoxications with a variety of metals can be considerable improved by administration of a suitable chelating agent. In this review the chemical characteristics, properties and uses of the most common chelating agents as well as those of some new and very promising agents of this type, are discussed. In the second part of the review the biological and biochemical impact of these agents, as well as their use for the treatment of some selected diseases and disorders, are also analyzed and discussed in detail.
publishDate 2010
dc.date.none.fl_str_mv 2010-11
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/103522
Baran, Enrique José; Chelation Therapies: A Chemical and Biochemical Perspective; Bentham Science Publishers; Current Medicinal Chemistry; 17; 31; 11-2010; 3658-3672
0929-8673
1875-533X
CONICET Digital
CONICET
url http://hdl.handle.net/11336/103522
identifier_str_mv Baran, Enrique José; Chelation Therapies: A Chemical and Biochemical Perspective; Bentham Science Publishers; Current Medicinal Chemistry; 17; 31; 11-2010; 3658-3672
0929-8673
1875-533X
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.ncbi.nlm.nih.gov/pubmed/20846112
info:eu-repo/semantics/altIdentifier/url/http://www.eurekaselect.com/72556/article
info:eu-repo/semantics/altIdentifier/doi/10.2174/092986710793213760
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Bentham Science Publishers
publisher.none.fl_str_mv Bentham Science Publishers
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1844614514318770176
score 13.070432

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