Multiple functional targets of the immunoregulatory activity of galectin-1 : Control of immune cell trafficking, dendritic cell physiology, and T-cell fate

Autores
Cooper, Dianne; Ilarregui, Juan Martin; Pesoa, Susana A.; Croci Russo, Diego Omar; Perretti, Mauro; Rabinovich, Gabriel Adrian
Año de publicación
2010
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
In the postgenomic era, the study of the glycome- the whole repertoire of saccharides in cells and tissues- has enabled the association of unique glycan structures with specific physiological and pathological processes. The responsability for deciphering this biological information belongs to endogenous glycan-binding proteins or lectins. Galectin-1, a prototype member of a family of structurally-related proteins, has demonstrated selective antiinflammatory and immunoregulatory effects either by controlling immune cell trafficking, fine-tuning dendritic cell physiology and regulating T cell phate. These regulatory functions mediated by an endogenous glycan-binding protein may contribute tuo fullfil the needs for immune cell homeostasis.
Fil: Cooper, Dianne. Queen Mary University of London. The William Harvey Research Institute; Reino Unido
Fil: Ilarregui, Juan Martin. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina; Argentina. Queen Mary University of London. The William Harvey Research Institute; Reino Unido
Fil: Pesoa, Susana A.. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina; Argentina
Fil: Croci Russo, Diego Omar. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina; Argentina
Fil: Perretti, Mauro. Queen Mary University of London. The William Harvey Research Institute; Reino Unido
Fil: Rabinovich, Gabriel Adrian. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica; Argentina
Materia
Galectins
Dendritic Cells
Neutrophils
Trafficking
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/14675
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/14675
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Multiple functional targets of the immunoregulatory activity of galectin-1 : Control of immune cell trafficking, dendritic cell physiology, and T-cell fateCooper, DianneIlarregui, Juan MartinPesoa, Susana A.Croci Russo, Diego OmarPerretti, MauroRabinovich, Gabriel AdrianGalectinsDendritic CellsNeutrophilsTraffickinghttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1https://purl.org/becyt/ford/3.1https://purl.org/becyt/ford/3In the postgenomic era, the study of the glycome- the whole repertoire of saccharides in cells and tissues- has enabled the association of unique glycan structures with specific physiological and pathological processes. The responsability for deciphering this biological information belongs to endogenous glycan-binding proteins or lectins. Galectin-1, a prototype member of a family of structurally-related proteins, has demonstrated selective antiinflammatory and immunoregulatory effects either by controlling immune cell trafficking, fine-tuning dendritic cell physiology and regulating T cell phate. These regulatory functions mediated by an endogenous glycan-binding protein may contribute tuo fullfil the needs for immune cell homeostasis.Fil: Cooper, Dianne. Queen Mary University of London. The William Harvey Research Institute; Reino UnidoFil: Ilarregui, Juan Martin. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina; Argentina. Queen Mary University of London. The William Harvey Research Institute; Reino UnidoFil: Pesoa, Susana A.. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina; ArgentinaFil: Croci Russo, Diego Omar. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina; ArgentinaFil: Perretti, Mauro. Queen Mary University of London. The William Harvey Research Institute; Reino UnidoFil: Rabinovich, Gabriel Adrian. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica; ArgentinaElsevier2010-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/14675Cooper, Dianne; Ilarregui, Juan Martin; Pesoa, Susana A.; Croci Russo, Diego Omar; Perretti, Mauro; et al.; Multiple functional targets of the immunoregulatory activity of galectin-1 : Control of immune cell trafficking, dendritic cell physiology, and T-cell fate; Elsevier; Methods In Enzymology.; 480; 9-2010; 199-2440076-68791557-7988enginfo:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0076687910800114info:eu-repo/semantics/altIdentifier/doi/10.1016/S0076-6879(10)80011-4info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-nd/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2025-09-29T10:18:27Zoai:ri.conicet.gov.ar:11336/14675instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982025-09-29 10:18:27.666CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Multiple functional targets of the immunoregulatory activity of galectin-1 : Control of immune cell trafficking, dendritic cell physiology, and T-cell fate
title Multiple functional targets of the immunoregulatory activity of galectin-1 : Control of immune cell trafficking, dendritic cell physiology, and T-cell fate
spellingShingle Multiple functional targets of the immunoregulatory activity of galectin-1 : Control of immune cell trafficking, dendritic cell physiology, and T-cell fate
Cooper, Dianne
Galectins
Dendritic Cells
Neutrophils
Trafficking
title_short Multiple functional targets of the immunoregulatory activity of galectin-1 : Control of immune cell trafficking, dendritic cell physiology, and T-cell fate
title_full Multiple functional targets of the immunoregulatory activity of galectin-1 : Control of immune cell trafficking, dendritic cell physiology, and T-cell fate
title_fullStr Multiple functional targets of the immunoregulatory activity of galectin-1 : Control of immune cell trafficking, dendritic cell physiology, and T-cell fate
title_full_unstemmed Multiple functional targets of the immunoregulatory activity of galectin-1 : Control of immune cell trafficking, dendritic cell physiology, and T-cell fate
title_sort Multiple functional targets of the immunoregulatory activity of galectin-1 : Control of immune cell trafficking, dendritic cell physiology, and T-cell fate
dc.creator.none.fl_str_mv Cooper, Dianne
Ilarregui, Juan Martin
Pesoa, Susana A.
Croci Russo, Diego Omar
Perretti, Mauro
Rabinovich, Gabriel Adrian
author Cooper, Dianne
author_facet Cooper, Dianne
Ilarregui, Juan Martin
Pesoa, Susana A.
Croci Russo, Diego Omar
Perretti, Mauro
Rabinovich, Gabriel Adrian
author_role author
author2 Ilarregui, Juan Martin
Pesoa, Susana A.
Croci Russo, Diego Omar
Perretti, Mauro
Rabinovich, Gabriel Adrian
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Galectins
Dendritic Cells
Neutrophils
Trafficking
topic Galectins
Dendritic Cells
Neutrophils
Trafficking
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
https://purl.org/becyt/ford/3.1
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv In the postgenomic era, the study of the glycome- the whole repertoire of saccharides in cells and tissues- has enabled the association of unique glycan structures with specific physiological and pathological processes. The responsability for deciphering this biological information belongs to endogenous glycan-binding proteins or lectins. Galectin-1, a prototype member of a family of structurally-related proteins, has demonstrated selective antiinflammatory and immunoregulatory effects either by controlling immune cell trafficking, fine-tuning dendritic cell physiology and regulating T cell phate. These regulatory functions mediated by an endogenous glycan-binding protein may contribute tuo fullfil the needs for immune cell homeostasis.
Fil: Cooper, Dianne. Queen Mary University of London. The William Harvey Research Institute; Reino Unido
Fil: Ilarregui, Juan Martin. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina; Argentina. Queen Mary University of London. The William Harvey Research Institute; Reino Unido
Fil: Pesoa, Susana A.. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina; Argentina
Fil: Croci Russo, Diego Omar. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina; Argentina
Fil: Perretti, Mauro. Queen Mary University of London. The William Harvey Research Institute; Reino Unido
Fil: Rabinovich, Gabriel Adrian. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental (i); Argentina; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Biológica; Argentina
description In the postgenomic era, the study of the glycome- the whole repertoire of saccharides in cells and tissues- has enabled the association of unique glycan structures with specific physiological and pathological processes. The responsability for deciphering this biological information belongs to endogenous glycan-binding proteins or lectins. Galectin-1, a prototype member of a family of structurally-related proteins, has demonstrated selective antiinflammatory and immunoregulatory effects either by controlling immune cell trafficking, fine-tuning dendritic cell physiology and regulating T cell phate. These regulatory functions mediated by an endogenous glycan-binding protein may contribute tuo fullfil the needs for immune cell homeostasis.
publishDate 2010
dc.date.none.fl_str_mv 2010-09
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/14675
Cooper, Dianne; Ilarregui, Juan Martin; Pesoa, Susana A.; Croci Russo, Diego Omar; Perretti, Mauro; et al.; Multiple functional targets of the immunoregulatory activity of galectin-1 : Control of immune cell trafficking, dendritic cell physiology, and T-cell fate; Elsevier; Methods In Enzymology.; 480; 9-2010; 199-244
0076-6879
1557-7988
url http://hdl.handle.net/11336/14675
identifier_str_mv Cooper, Dianne; Ilarregui, Juan Martin; Pesoa, Susana A.; Croci Russo, Diego Omar; Perretti, Mauro; et al.; Multiple functional targets of the immunoregulatory activity of galectin-1 : Control of immune cell trafficking, dendritic cell physiology, and T-cell fate; Elsevier; Methods In Enzymology.; 480; 9-2010; 199-244
0076-6879
1557-7988
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.sciencedirect.com/science/article/pii/S0076687910800114
info:eu-repo/semantics/altIdentifier/doi/10.1016/S0076-6879(10)80011-4
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-nd/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1844614146875719680
score 13.070432

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